Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Dihydrotestosterone-2,3,4-13C3 solution | 0.1 mg/mL in methanol, 99 atom % 13C, 97% (CP). Group: Fluorescence/luminescence spectroscopy. |  |
| 5?-Dihydrotestosterone-D3 (16,16,17-D3) solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| 17α-Hydroxy-5α-androstan-3-one | 17α-Hydroxy-5α-androstan-3-one. Group: Biochemicals. Alternative Names: 17-epi-Dihydrotestosterone; 17α-Hydroxy-5α-androstane-3-one; 5α-Androstan-17α-ol-3-one; Di hydroepitestosterone; epi-Dihydrotestosterone. Grades: Highly Purified. CAS No. 571-24-4. Pack Sizes: 10mg. Molecular Formula: C19H30O2, Molecular Weight: 290.44. US Biological Life Sciences. |  Worldwide |
| 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol | 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT). Group: Biochemicals. Grades: Highly Purified. CAS No. 1375064-29-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences. | Worldwide |
| 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol-d3 | 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol-d3 is the isotope labelled analog of 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol. 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H31D3O3, Molecular Weight: 325.5. US Biological Life Sciences. | Worldwide |
| 17α-Methyl-androstan-3-hydroxyimine-17 β-ol | 17α-Methyl-androstan-3-hydroxyimine-17 β-ol is an analog of Mestanolone (M225790), a 17α-methylated version of dihydrotestosterone and is a designer anabolic androgenic steroid. Group: Biochemicals. Grades: Highly Purified. CAS No. 2722-75-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H33NO2, Molecular Weight: 319.48. US Biological Life Sciences. | Worldwide |
| 17 β-Acetoxy-2α-bromo-5α-androstanone | A steroid analog with inhibitive effects in progesterone synthesis and in dihydrotestosterone binding to receptor protein. Group: Biochemicals. Alternative Names: 17 β-Acetoxy-2α-bromo-5α-androstan-3-one; 2α-Bromo-17 β-hydroxy-5α-androstan-3-one Acetate. Grades: Highly Purified. CAS No. 6173-35-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 17Beta-hydroxy-5alpha-androstan-3-one propionate | 17Beta-hydroxy-5alpha-androstan-3-one propionate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 17beta-hydroxy-5alpha-androstan-3-one propionate;(5α)-4,5-Dihydrotestosterone 17-propionate;17β-(Propionyloxy)-5α-androstane-3-one;17β-Propionyloxy-5α-androstan-3-one;Androstanolone propionate;DHTP;[(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5. Product Category: Heterocyclic Organic Compound. CAS No. 855-22-1. Molecular formula: C22H34O3. Mole weight: 346.50356. Product ID: ACM855221. Alfa Chemistry ISO 9001:2015 Certified. Categories: Dihydrotestosterone propionate. |  |
| 2-a-Methyl-5-a-androstan-3-a-ol-17-one glucuronide | 2-a-Methyl-5-a-androstan-3-a-ol-17-one glucuronide is a biomedical product extensively employed in the realm of biomedicine for conducting steroid metabolism studies, demonstrating remarkable utility as a substrate by being intricately metabolized by a multitude of enzymes. This unique attribute enables the thorough assessment and comprehensive analysis of crucial steroid hormones, including but not limited to testosterone and dihydrotestosterone. Molecular formula: C26H39O8.Na. Mole weight: 502.57. |  |
| 3α-hydroxysteroid 3-dehydrogenase | The enzyme acts on multiple 3α-hydroxysteroids, such as androsterone and 5 α-dihydrotestosterone. The mammalian enzymes are involved in inactivation of steroid hormones, while the bacterial enzymes are involved in steroid degradation. This entry stands for enzymes whose stereo-specificity with respect to NAD+ or NADP+ is not known. [cf. EC 1.1.1.50, 3α-hydroxysteroid 3-dehydrogenase (Si-specific) and EC 1.1.1.213, 3α-hydroxysteroid 3-dehydrogenase (Re-specific)]. Group: Enzymes. Synonyms: 3α-hydroxysteroid dehydrogenase; AKR1C4 (gene name); AKR1C2 (gene name); hsdA (gene name). Enzyme Commission Number: EC 1.1.1.357. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0273; 3α-hydroxysteroid 3-dehydrogenase; EC 1.1.1.357; 3α-hydroxysteroid dehydrogenase; AKR1C4 (gene name); AKR1C2 (gene name); hsdA (gene name). Cat No: EXWM-0273. |  |
| 3-Fluoro-4-desfluoro Bicalutamide | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: (RS)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(3-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide; Bicalutamide 3-fluoro isomer; Bicalutamide Related Compound B; Bicalutamide USP Related Compound B; USP Bicalutamide Related Compound B; 3-Fluorophenyl Bicalutamide; Bicalutamide USP RC B. Grade: >95%. CAS No. 1166228-30-3. Molecular formula: C18H14F4N2O4S. Mole weight: 430.38. | |
| 3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17 β-carboxylic Acid Methyl Ester | 3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17 β-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1026013-15-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid | An intermediate in the synthesis of Finasteride, am onhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-Oxo-4-azaandrosta-1,5,7-triene-17-carboxylic Acid Methyl Ester | 3-Oxo-4-azaandrosta-1,5,7-triene-17-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Group: Biochemicals. Alternative Names: [4aR-(4aα,4b β, 6aα, 7α, 9a β)]-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a-Decahydro-4a, 6a-dimethyl-3-oxo-1H-indeno[5, 4-f]quinoline-7-carboxylic Acid Methyl Ester; (4aR, 4bS, 6aS, 7S, 9aR)-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a-Decahydro-4a, 6a-dimethyl-3-oxo-1H-indeno[5, 4-f]quinoline-7-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 166896-63-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5α-Androstan-3α-ol-17-one-[16,16-d2] 3-glucuronide | 5α-Androstan-3α-ol-17-one-[16,16-d2] 3-glucuronide is the labelled analogue of Androsterone glucuronide, which is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT). Synonyms: β-D-Glucopyranosiduronic acid, (3α,5α)-17-oxoandrostan-3-yl-16,16-d2; (3α,5α)-17-Oxo(16,16-d2)androstan-3-yl β-D-glucopyranosiduronic acid; Androstan-17-one-16,16-d2, 3-(β-D-glucopyranuronosyloxy)-, (3α,5α)-; Androsterone-16,16-d2 glucuronide; 5α-Androstan-3α-ol-17-one-16,16-d2-glucosiduronate; 17-Oxo-5α-androstan-3α-yl-16,16-d2 β-D-glucopyranosiduronic acid. Grade: ≥95%; 99% atom D. CAS No. 362049-52-3. Molecular formula: C25H36D2O8. Mole weight: 468.58. | |
| 5-Amino-2-cyanobenzotrifluoride | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity D; Bicalutamide EP Impurity D; 4-Amino-α,α,α-trifluoro-o-tolunitrile; 2-Trifluoromethyl-4-aminobenzonitrile; 4-Cyano-3-(trifluoromethyl)aniline; 4-Amino-2-trifluoromethylbenzonitrile; 4-Cyano-3-(trifluoromethyl)aniline; Bicalutamide aminobenzonitrile; 2-Cyano-5-aminobenzotrifluoride. Grade: >95%. CAS No. 654-70-6. Molecular formula: C8H5F3N2. Mole weight: 186.14. | |
| (6aS,7S,9aR)-2,5,6,6a,7,8,9,9a-Octahydro-6a-methyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester | (6aS,7S,9aR)-2,5,6,6a,7,8,9,9a-Octahydro-6a-methyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Group: Biochemicals. Alternative Names: [6aS-(6aα,7α,9a β)]-2,5,6,6a,7,8,9,9a-Octahydro-6a-methyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester; (17 β)-3-Oxo-4-azaestra-1,5,7,9-tetraene-17-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 166896-66-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ack1 Inhibitor, AIM-100 (Activated Cdc42 Kinase 1 Inhibitor, (S)-5,6-Diphenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine) | A cell-permeable furopyrimidine that acts as a potent, ATP-binding site-targeting, Ack1-selective inhibitor (IC50 = 22nM) and effectively prevents receptor-mediated Ack1 activation (by >90% in MEF & LAPC4 cultures; 16h 800nM), while exhibiting much reduced potency against Lyn, Lck, Abl1 and BTK (IC50 ≥346.7nM) and no inhibitory activity toward 25 other kinases. Shown to completely inhibit EGF-induced, but not androgen DHT- (dihydrotestosterone) stimulated, AR transcription activity in serum- and androgen-deprived prostate cancer LAPC4 cutlures. Effectively inhibits androgen-independent LNCaP prostate cancer growth both in vitro (by 60%; 72h 8uM) and in castrated mice in vivo (4mg/kg/96h injections on day 7/11/15/19/23/27 post tumor transplant). Group: Biochemicals. Grades: Highly Purified. CAS No. 873305-35-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Androstanolone acetate | Androstanolone acetate. Group: Biochemicals. Alternative Names: 5a-Dihydrotestosterone acetate; Androstanolone acetate; Dihydrotestosterone acetate. Grades: Highly Purified. CAS No. 1164-91-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C21H32O3. US Biological Life Sciences. | Worldwide |
| Androstanolone acetate | Androstanolone acetate is an androgen ligand, which targets androgen receptor. Androstanolone acetate binds to cIAP1 ligand Bestatin via a linker to form PROTACs. Synonyms: Dihydrotestosterone acetate; 17-O-Acetyl Androstanolone; Stanolone Acetate; 5α-Dihydrotestosterone Acetate. Grade: 95%. CAS No. 1164-91-6. Molecular formula: C21H32O3. Mole weight: 332.48. | |
| Bicalutamide EP Impurity E | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity E; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(RS)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| Bicalutamide EP Impurity F | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity F; (2SR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(RS)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| Bicalutamide EP Impurity H | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity H; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-[(4-fluorophenyl)sulfonyl]-3-hydroxy-2-methylpropanamide; N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-[(4-fluorophenyl)sulfonyl]-3-hydroxy-2-methylpropanamide. Grade: ≥95%. CAS No. 2512198-58-0. Molecular formula: C18H14F4N2O4S. Mole weight: 430.37. | |
| Bicalutamide EP Impurity K | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity K; (2R,2'S)-3,3'-Sulfonylbis[N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide]; (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(((R)-3-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-hydroxy-2-methyl-3-oxopropyl)sulfonyl)-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C24H20F6N4O6S. Mole weight: 606.49. | |
| Bicalutamide EP Impurity L | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity L; (2RS,2'RS)-3,3'-Sulfonylbis[N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide]; 3,3'-Sulfonylbis(N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide). Grade: ≥95%. CAS No. 2711603-77-7. Molecular formula: C24H20F6N4O6S. Mole weight: 606.49. | |
| Bicalutamide EP Impurity M | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity M; (2RS)-3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic acid; 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic acid; (+/-)-3-((4-Fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanoic acid. Grade: >95%. CAS No. 151262-57-6. Molecular formula: C10H11FO5S. Mole weight: 262.26. | |
| Bicalutamide related compound A isomer A | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| Bicalutamide related compound A isomer B | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| Bicalutamide Sulfide | An intermediate of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity J; N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenylthio)-2-hydroxy-2-methylpropanamide; (+/-)-Bicalutamide sulfide; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfanyl]-2-hydroxy-2-methylpropanamide; (+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methyl-propanamide; (R,S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide; Bicalutamide EP Impurity J. Grade: >95%. CAS No. 90356-78-8. Molecular formula: C18H14F4N2O2S. Mole weight: 398.38. | |
| Bicalutamide Sulfoxide | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Related Compound A; Bicalutamide USP RC A; N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide; N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide; USP Bicalutamide Related Compound A; Bicalutamide USP Related Compound A. Grade: >95%. CAS No. 945419-64-7. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| CGP-53153 | CGP-53153 is a steroidal inhibitor of 5 alpha reductase is a steroidal which effects the conversion of testosterone (T) to 5α-dihydrotestosterone (DHT). In vitro, CGP 53153 competitively inhibited rat microsomal 5α-reductase from prostate by 50% (ICs0) at a concentration of 36 nM compared to the reference compound finasteride which inhibited 5α-reductase with an ICs0 of 11 nM in the same system. In vivo, inhibition of 5α-reductase activity was characterized in three different test systems. Synonyms: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-(2-cyanopropan-2-yl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide; wt1-ricin a; SCHEMBL8823373; CGP 53153; CGP-53153; CGP53153. CAS No. 149281-19-6. Molecular formula: C23H33N3O2. Mole weight: 383.53. | |
| Cl-4AS-1 | Cl-4AS-1 is a mouse mammary tumor virus (MMTV) promoter and represses MMP1 promoter activity. It also inhibits 5α-Reductase type I and II with IC50 values of 6 and 10 nM respectively, as well as is a potent steroidal androgen receptor agonist with IC50 value of 12 nM. It mimics the action of 5α-dihydrotestosterone (DHT). Synonyms: (4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: ≥99% by HPLC. CAS No. 188589-66-4. Molecular formula: C26H33ClN2O2. Mole weight: 441.01. | |
| D-3263 | D-3263 is a TRPM8 agonist ( transient receptor potential melastatin member 8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer. Synonyms: 3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one; 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥95%. CAS No. 947257-66-1. Molecular formula: C21H31N3O3. Mole weight: 373.49. | |
| Desfluoro Bicalutamide | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity A; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide; (+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide; N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide; Bicalutamide EP Impurity A; (+/-)-Desfluoro bicalutamide. Grade: >95%. CAS No. 90357-05-4. Molecular formula: C18H15F3N2O4S. Mole weight: 412.39. | |
| Deshydroxy Bicalutamide | An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity C; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-methylpropanamide; Bicalutamide EP Impurity C; Deoxybicalutamide; Dehydroxybicalutamide; Bicalutamide Deshydroxy Impurity. Grade: >95%. CAS No. 906008-94-4. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38. | |
| Dutasteride | Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Synonyms: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5α,17β)-; (5α,17β)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide; Avodart; Avolve; GG 745; GI 198745; Veltride. Grade: >98%. CAS No. 164656-23-9. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. | |
| Dutasteride-[13C6] | Dutasteride-[13C6] is the labelled analogue of Dutasteride. Dutasteride is a triple 5α-reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone. Dutasteride is a medication primarily used to treat the symptoms of an enlarged prostate. Synonyms: Dutasteride 13C6. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1217685-27-2. Molecular formula: C21[13C]6H30F6N2O2. Mole weight: 534.49. | |
| Epristeride | Epristeride is a medication primarily used to treat benign prostatic hyperplasia (BPH), which is an enlarged prostate gland. Epristeride is a 5-alpha-reductase inhibitor. It works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT). DHT is a potent androgen that contributes to prostate growth. By reducing DHT levels, epristeride helps decrease the size of the prostate and alleviate symptoms of BPH. Epristeride is used to manage symptoms of BPH, such as difficulty in urination, increased urinary frequency, and urinary retention. Synonyms: ONO-9302; 17β-(tert-Butylaminocarbonyl)androsta-3,5-diene-3-carboxylic acid; Androsta-3,5-diene-3-carboxylic acid, 17-(((1,1-dimethylethyl)amino)carbonyl)-, (17β)-; SKF105657. Grade: 95%. CAS No. 119169-78-7. Molecular formula: C25H37NO3. Mole weight: 399.57. | |
| Finasteride | Finasteride (INN, USAN, BAN) (brand names Proscar, and Propecia by Merck, among other generic names; former developmental code name MK-906) is a drug used for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). It is a type II and type III 5α-reductase inhibitor; 5α-reductase, an enzyme, converts testosterone to dihydrotestosterone (DHT). Uses: Api. Synonyms: MK-906; MK 906; MK906; Propecia; Proscar; N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide; N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide. Grade: 99%. CAS No. 98319-26-7. Molecular formula: C23H36N2O2. Mole weight: 372.5. | |
| Finasteride | Finasteride is a basic drug for the treatment of prostatic hyperplasia and prostatitis in China. It is a synthetic 4-nitrosteric hormone compound and a resistant hormone drug. It can selectively inhibit 5α - reductase, inhibit the process of transforming testosterone into 5α - dihydrotestosterone (DHT), and reduce the level of androgen Chemicalbook in prostate cells. Serum prostate-specific antigen decreased, enlarged prostate volume decreased, urine flow rate increased, thereby reducing the symptoms of patients, to achieve the purpose of treating prostate hyperplasia. The action of the drug is characterized by the selective blocking of androgen stimulation of the prostate gland, but it rarely affects the sexual function of men. CAS No. 98319-26-7. Product ID: PAP-0090. Molecular formula: C23H36N2O2. Product Keywords: Other Active Pharmaceutical Ingredients; Finasteride; PAP-0090; ; C23H36N2O2; 98319-26-7. Appearance: Solid. Grade: GMP. Color: white to beige. EC Number: 620-534-3. Physical State: solid. Solubility: DMSO: 32 mg/mL, soluble. Storage: room temp. Applications: Finasteride is a specific inhibitor of intracellular enzyme type II 5A-reductase in the process of testosterone metabolism to dihydrotestosterone, which can effectively reduce the dihydrotestosterone in the blood and prostate, that is, by inhibiting the conversion of testosterone into dihydrotestosterone (DHT), reduce the size of the pros |  |
| Finasteride-d9 | The labeled version of Finasteride. An inhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Finasteride (MK 906, L-652,931, BRN 4269024 ) | Potent, specific and competitive inhibitor of type II 5alpha-reductase (enzyme which converts testosterone to the more potent 5alpha-dihydrotestosterone). Anticancer compound. Apoptosis modulator. Enhances the action of GABA at GABA(A) receptors, which leads to neurological implications. Inhibit testosterone-induced type I procollagen and TGF-b1 expression in human scalp dermal fibroblasts in a model of androgenic alopecia. Drug for the treatment of male androgenetic alopecia. Potential role in neuropsychiatric disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 98319-26-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C23H36N2O2, Form: Supplied as a white to off-white. US Biological Life Sciences. | Worldwide |
| Finasteride (MK-906, Proscar, Prostide, Finastid,) | Inhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Group: Biochemicals. Alternative Names: MK-906, Proscar, Prostide, Finastid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Methyl 1-Testosterone | Methyl-1-Testosterone is a derivative of dihydrotestosterone. Methyl-1-Testosterone is a designer anabolic steroid that is on the world anti-doping agencyÂs (WADA) prohibited list. Group: Biochemicals. Grades: Highly Purified. CAS No. 65-04-3. Pack Sizes: 25mg, 100mg. Molecular Formula: C20H30O2. US Biological Life Sciences. | Worldwide |
| Neoaureothin | Neoaureothin is a metabolite produced by Streptomyces. It acts as an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM). Synonyms: 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrien-1-ylidene]-2-furanyl]-; 2-Methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrien-1-ylidene]-2-furanyl]-4H-pyran-4-one; 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[tetrahydro-4-[2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrienylidene]-2-furanyl]-, (Z,E,E,E)-(+)-; (+)-Spectinabilin; NSC 260179; Spectinabilin; Spectinabiline. Grade: ≥98%. CAS No. 59795-94-7. Molecular formula: C28H31NO6. Mole weight: 477.55. | |
| Saw Palmeto Berry Extract (Standard) | Saw Palmetto (Serenoa Repens): The medicinal parts are the partially dried ripe fruit, the ripe fresh fruit and the ripe dried fruit, The plant is indigenous to the coastal regions of the southern states of the U.S., from South Carolina to Florida and southern California. Applications: Anti-androgenic effects: the lipophilic extract of the herb inhibits binding of dihydrotestosterone (dht) to the cytosolic androgenic receptor and alpha-1 adrenergic receptor in the prostate, thus preventing accumulation of the steroid, which may lead to prostate hyperplasia.anti-inflammatory effects: the extracts of the herb have demonstrated anti-inflammatory activity. inhibition of the synthesis of arachidonic acid inflammatory metobolits, through a double blocking of cyclooxygenas and 5-lipoxy-genase pathways results in anti-inflammatory properties. Group: Others. Purity: 25.0%,45.0% Fatty Acids GC. Saw Palmeto Berry Extract (Standard). Cat No: EXTW-014. | |
| Stanozolol-d3 | Isotope labelled analogue of Stanozolol (S684500), a synthetic anabolic steroid derived from dihydrotestosterone (A637540). Group: Biochemicals. Grades: Highly Purified. CAS No. 792214-66-5. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C21H29D3N2O. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
