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| Product | Description | |
|---|---|---|
| (2-cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite | N,N-diisopropylphosphoramidite, a catalytic compound, is an essential building block for oligonucleotide synthesis used in various therapeutic domains such as antisense therapy, siRNA, and gene editing. This efficient and highly pure chemical ensures the production of top-quality therapeutic oligonucleotides. Synonyms: Chemical phosphorylation reagent for oligonucleotide synthesis;Propanedioic acid, [[bis (4-methoxyphenyl) phenylmethoxy]methyl][[[[bis (1-methylethyl) amino] (2-cyanoethoxy)phosphino]oxy]methyl]-, diethyl ester; CP?; CPRII; 2-[ (4, 4'-Dimethoxytrityloxy) methyl]-2-[[ (diisopropylamino) (2-cyanoethoxy) phosphinooxy]methyl]malonic acid diethyl ester; Diethyl {[bis (4-methoxyphenyl) (phenyl) methoxy]methyl} ({[ (2-cyanoethoxy) (diisopropylamino) phosphino]oxy}methyl) malonate. Grades: ≥97% by HPLC. CAS No. 171285-25-9. Molecular formula: C39H51N2O9P. Mole weight: 722.80. |  |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -4-fluoro-5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -4-fluoro-5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite, a critical chemical reagent in the biomedicine industry, demonstrates immense value for the synthesis of nucleosides and nucleotides. Its pivotal role lies within the realm of research and development of pharmaceuticals, particularly anti-cancer and antiviral drugs. CAS No. 2376756-54-4. Molecular formula: C43H52FN8O6P. Mole weight: 826.9. | |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite, a critical component within the biomedical industry, exhibits remarkable significance. Serving as an essential foundational unit for the synthesis of nucleoside phosphoramidites and diverse bioactive compounds, this compound profoundly impacts the realm of drug discovery, particularly towards the development of innovative antiviral and anticancer agents. CAS No. 182935-50-5. Molecular formula: C38H45FN5O6P. Mole weight: 717.77. | |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite exhibits paramount significance within the biomedical industry. It serves as a vital ingredient in oligonucleotide synthesis for multifarious applications encompassing gene expression analysis, antisense technology, and the pioneering sector of drug development. CAS No. 2376756-55-5. Molecular formula: C44H55N8O7P. Mole weight: 838.93. | |
| 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite | 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite, a remarkable biomedicine agent, serves as a pivotal component in the synthesis of diverse therapeutic agents that effectively combat diseases of distinct etiologies, including cancer and neurodegenerative disorders. Leveraging its profound chemical prowess and efficacy, this invaluable entity propels the frontiers of pharmaceutical research and development, facilitating the innovation of novel bioactive compounds with promising therapeutic potential. As it attains precise and expeditious chemical synthesis, this indispensable product impels the progress of biomedicine to unprecedented heights. Synonyms: 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite; [(2R)-3-(2-cyanoethyl)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy-[di(propan-2-yl)amino]phosphinite. CAS No. 1772522-16-3. Molecular formula: C38H66N2O3P-. Mole weight: 629.9. | |
| (2R, 3R, 4R, 5R)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | (2R, 3R, 4R, 5R)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite, an indispensable phosphoramidite reagent, demonstrates immense significance within the realm of biomedicine. Its role primarily revolves around its extensive utilization in synthesizing oligonucleotides for a diverse range of crucial applications. These include the fields of gene therapy, molecular diagnostics, and antisense therapy. CAS No. 1797762-50-6. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| (2R, 3R, 4R, 5R)-5- (6-Amino-9H-purin-9-yl)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | (2R, 3R, 4R, 5R)-5- (6-Amino-9H-purin-9-yl)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is an intricate and versatile compound in the realm of biomedical research. Its utilization lies predominantly in the synthesis of nucleotides and nucleic acids, catering to an array of molecular biology and drug discovery applications. This product can serve as a paramount resource for drug development investigations, gene expression analysis, and genetic scrutiny. CAS No. 252770-65-3. Molecular formula: C40H47FN7O6P. Mole weight: 771.82. | |
| ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite | ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite is a fundamental reagent for the synthesis of augmented nucleosides and oligonucleotides. This phosphoramidite compound plays a crucial role in facilitating research on therapeutic strategies associated with a variety of diseases, be it viral infections, hereditary diseases, or even the malignant ravages of cancer. CAS No. 2376756-43-1. Molecular formula: C46H50FN8O5P. Mole weight: 844.91. | |
| Bis(2-cyanoethyl) diisopropylphosphoramidite | Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Group: Signaling pathways. CAS No. 102690-88-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-24126. |  |
| Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite | A useful phosphorylating reagent. Synonyms: N,N-bis(1-Methylethyl)phosphoramidous acid bis(2-cyanoethyl) ester; Bis(2-cyanoethyl) diisopropylphosphoramidite; Bis (2-cyanoethoxy) (diisopropylamino)phosphine; Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine; Phosphoramidous acid, bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(2-cyanoethyl) ester. Grades: 96%. CAS No. 102690-88-0. Molecular formula: C12H22N3O2P. Mole weight: 271.30. | |
| Dibenzyl N,N-diisopropylphosphoramidite | Dibenzyl diisopropylphosphoramidite is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 108549-23-1. Pack Sizes: 10 g; 25 g. Product ID: HY-W013777. | |
| Dibenzyl-N,N-diisopropylphosphoramidite | Dibenzyl-N,N-diisopropylphosphoramidite. CAS No: 108549-23-1 |  Sarchem Laboratories New Jersey NJ |
| Di-tert-butyl diisopropylphosphoramidite | Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Group: Signaling pathways. CAS No. 137348-86-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W009354. | |
| 2,?4(1H,?3H)?-?Pyrimidinedione, 1-?[5-?O-?[[bis (1-?methylethyl) ?amino]? (2-?cyanoethoxy) ?phosphino]?-?2, ?3-?dideoxy-?2-?fluoro-?3-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?β -?D-?arabinofuranosyl]?-?5-?methyl- | The biochemical 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-2-fluoro-3-[[(4-methoxyphenyl)diphenylmethyl]amino]-β-D-arabinofuranosyl]-5-methyl-, is well known in the biomedical realm due to its anticancer effects, serving as a therapeutic agent for acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma by impeding DNA synthesis and obstructing the propagation and dissemination of malignant cancerous cells, thereby proving to be an indispensable asset. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 329773-25-3. Molecular formula: C39H47FN5O6P. Mole weight: 731.79. | |
| 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite | 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a critical and widely used biochemical reagent in the biomedicine industry. Its primary function is to aid in the synthesis of RNA oligonucleotides needed for various research purposes, including the development of therapeutic oligonucleotides that target specific genetic disorders. Moreover, it serves as a fundamental tool for exploring the chemical modification of RNA molecules and its impact on different biological processes. Its significance in the biomedicine industry cannot be overstated. Synonyms: (2R, 3S, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-5- (2, 4-dioxo-5-vinyl-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 287980-24-9. CAS No. 287980-24-9. Molecular formula: C41H49N4O8P. Mole weight: 756.8. | |
| 2-O-DMT-sulfonyldiethanol phosphoramidite | 2-O-DMT-sulfonyldiethanol phosphoramidite substantiates its inevitable prowess in the synthesis and alteration of nucleic acids across diverse applications. Unparalleled in its chemical composition, this exceptional concoction facilitates meticulous and efficient manipulation of nucleic acids, thus fostering elevated biomedical exploration with incomparable precision. Synonyms: 2- ( (2- (bis (4-methoxyphenyl) (phenyl)methoxy)ethyl)sulfonyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[2-[bis (4-methoxyphenyl) phenylmethoxy]ethyl]sulfonyl]ethyl 2-cyanoethyl ester; 2-[2- (4, 4'-dimethoxytrityloxy) ethylsulfonyl]ethyl- (2-cyanoethyl) - (N, N-diisopropyl) -phosphoramidite; 2-O-DMT-S phosphoramidite. Grades: >95% by HPLC. CAS No. 108783-02-4. Molecular formula: C34H45N2O7PS. Mole weight: 656.77. | |
| 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite | 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite: This phosphoramidite derivative is essential in the biomedical industry for synthesizing modified RNA molecules. It acts as a building block during solid-phase RNA synthesis, enabling the introduction of 2'-O-tert-butyldimethylsilyl, 5'-O-DMT, and C2-methyladenosine modifications. This phosphoramidite facilitates research on RNA structure-function relationships, post-transcriptional modifications, and drug discovery targeting diseases like cancer and viral infections. Synonyms: (2R, 3R, 4R, 5R) -5- (6-Amino-2-methyl-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( (tert-butyldimethylsilyl) oxy) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1028723-99-0. Molecular formula: C47H64N7O7Si. Mole weight: 867.14. | |
| 5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite | 5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite, a bio-molecular tool, facilitates the integration of 5-aza-2'-deoxycytidine into oligonucleotides. This inhibits DNA methyltransferase and affords therapeutic benefits such as anti-cancer activity. The phosphoramidite reagent is a research asset that enables differential and accurate DNA sequence modification for targeted epigenetic investigation. It thus contributes to newer approaches in therapeutic interventions. Synonyms: (2R, 3S, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-5- (2-oxo-4- (2-phenoxyacetamido)-1, 3, 5-triazin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 929904-98-3. CAS No. 929904-98-3. Molecular formula: C46H53N6O9P. Mole weight: 864.92. | |
| 5'-DMT-2'O-TBDMS-rU Phosphoramidite | 5'-DMT-2'O-TBDMS-rU Phosphoramidite is a classic 2-OTBDMS phosphoramidite used to incorporate U into synthetic oligonucleotides. Synonyms: rU Phosphoramidite; (2R, 3R, 4R, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 97%. CAS No. 118362-03-1. Molecular formula: C45H61N4O9PSi. Mole weight: 861.04. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite, a highly valued compound within the biomedicine sector, plays a pivotal role in the synthetic production of altered nucleic acids. Primarily employed as a fundamental unit during oligonucleotide formation, it showcases tremendous potential in advancing RNA-based therapeutic interventions. Through its exceptional capability, this product empowers precise and effective nucleoside modification, enabling targeted remedies for an array of prevalent ailments including viral afflictions and hereditary anomalies. Synonyms: (2S, 3S, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-2- (1-methyl-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 875302-47-9. CAS No. 875302-47-9. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite | 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine. Grades: ≥ 98%. CAS No. 109389-30-2. Molecular formula: C39H47N4O8P. Mole weight: 730.8. | |
| 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite can introduce uridine units into the building blocks of non-natural DNA and RNA chains. Synonyms: 5'-O-(4,4'-Dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-yl]-2-cyanoethyl-N,N'-diisopropylphosphoramidite; 5'-O-DMT-2'-MOE-thymidine 3'-CE phosphoramidite; DMT-2'-O-MOE-T-CEP; 5-Me-DMT-2'-O-MOE-U-CE P. Grades: ≥98% by HPLC. CAS No. 163878-63-5. Molecular formula: C43H55N4O10P. Mole weight: 818.89. | |
| 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite | 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite is a novel nucleoside used in DNA and RNA synthesis. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite; (2R, 3R, 4R, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-2- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-TBDMS-ibu-rG Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N2-iBu-rG CED phosphoramidite. Grades: 95%. CAS No. 1445905-51-0. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs. Synonyms: N4-Benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite; dC(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grades: ≥98% by HPLC. CAS No. 102212-98-6. Molecular formula: C46H52N5O8P. Mole weight: 833.93. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-? (1, ?1-?difluoro-?2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a cutting-edge and highly effective modified nucleoside utilized in advanced biomedical research. With a distinctive and intricate chemical arrangement, it possesses unparalleled potential in gene therapies and drug delivery systems. This nucleoside has shown promising outcomes in the treatment and study of various genetic disorders and diseases, including cancer. Its exceptional stability and efficiency are beneficial in advancing research in these fields. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-70-0. Molecular formula: C49H55F2N8O7P. Mole weight: 936.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-? (2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a potent phosphoramidite recompound widely employed for the research of modified oligonucleotides, particularly in the development of nucleotide-based drugs targeting specific diseases such as cancer, viral infections and genetic disorders. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-93-1. Molecular formula: C49H57N8O7P. Mole weight: 901. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?ethyl-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an imperative compound, finding extensive application for oligonucleotide drugs research. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4-ethoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-74-1. Molecular formula: C48H55N8O6P. Mole weight: 870.97. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional compound used in the research of formidable malignancies, such as lymphoma and leukemia. Its utilization in the pursuit of innovative antiviral therapeutics that specifically target RNA viruses denotes its indispensable role. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (6-benzamido-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299282-94-1. Molecular formula: C49H55N8O6P. Mole weight: 882.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a complex chemical entity employed in the synthesis of oligonucleotides targeting viral infections and various cancers. The versatility of this remarkable molecule extends beyond biomedical research and treatment; it has the potential to alter genetic sequences, thereby opening new therapeutic avenues for myriad hitherto enigmatic human ailments. Its designation as a universally valuable synthetic building block in both academic and clinical milieus underscores its indispensability in biomedicine. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-22-0. Molecular formula: C47H53N8O6P. Mole weight: 856.95. | |
| Alkyne Phosphoramidite, 5'-terminal | Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry. This alkyne amidite has several advantages over 5'-hexynyl phosphoramidite, 5'-butynyl-CEP, and other 5'-terminal alkyne phosphoramidites. First, it is solid compound which is easier to handle and dispense. And due to its structure, it is also more stable in solution, and has longer shelf life. Synonyms: Alkyne Phosphoramidite; N-[4-[2-cyanoethoxy-[di (propan-2-yl) amino]phosphanyl]oxycyclohexyl]hex-5-ynamide; Rel-2-cyanoethyl ((1r,4r)-4-(hex-5-ynamido)cyclohexyl) diisopropylphosphoramidite. Grades: NMR 1H (95%) and 31P, HPLC-MS. CAS No. 1417539-32-2. Molecular formula: C21H36N3O3P. Mole weight: 409.50. | |
| Cytidine, N-?benzoyl-?2', ?3'-?dideoxy-?2'-?fluoro-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-2',3'-dideoxy-2'-fluoro-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a paramount pharmacological compound, exhibiting remarkable proficiency in facilitating the intricate research and development of perturbed nucleoside analog. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 182934-57-2. Molecular formula: C45H50FN6O6P. Mole weight: 820.89. | |
| Cytidine, N-?benzoyl-?2', ?3'-?dideoxy-?5-?methyl-?3'-?[ (triphenylmethyl)?amino]?-?, 5'-?[2-?cyanoethyl N, ?N-?bis (1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-2',3'-dideoxy-5-methyl-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a crucial compound used in the biomedical industry for synthesizing modified nucleotides. It plays a vital role in the creation of nucleotide analogs utilized in antiviral and anticancer drug development. This product ensures precise incorporation of modified nucleotides during DNA or RNA synthesis. Synonyms: ( (2S, 3S, 5R)-5- (4-benzamido-5-methyl-2-oxopyrimidin-1 (2H)-yl)-3- (tritylamino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 195375-70-3. Molecular formula: C45H51N6O5P. Mole weight: 786.9. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-? (1, ?1-?difluoro-?2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleotide analog that has shown promising results as an effective option for treating a wide range of life-threatening illnesses, including cancer, viral infections, and genetic disorders. Its remarkable capability to limit or obstruct the activity of pathological genes and proteins fills it with potential to revolutionize the biomedical sector. With its unique properties, this molecule could be the answer to targeted therapy and fulfill the growing need for a disease-specific cure. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-56-2. Molecular formula: C48H55F2N6O8P. Mole weight: 912.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-2'-O-[ (1, ?1-dimethylethyl) ?dimethylsilyl]?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- ( (tert-butyldimethylsilyl) oxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-? (2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional bioactive compound extensively applied in the biomedical domain, exhibiting unparalleled potency in studying diverse pathological conditions, predominantly those associated with intricate RNA metabolism and gene expression modulation. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-82-8. Molecular formula: C48H57N6O8P. Mole weight: 876.98. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a key ingredient in the synthesis of antisense oligonucleotides (ASOs), which facilitate the mitigation or remediation of diseases by specifically targeting genes or proteins implicated in disease pathogenesis. MMEDIATELY upon its incorporation into the ASO production process, Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] effects a robust increase in the fidelity and specificity of the synthesized ASOs. Clinical applications of ASOs incorporating Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] range from the attenuation or eradication of neoplastic lesions to remarkable amelioration of chronic viral syndromes and other genetic maladies. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-53-5. Molecular formula: C48H55N6O7P. Mole weight: 858.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?[2-? (trifluoromethoxy) ?ethyl]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-[2-(trifluoromethoxy)ethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic compound with a high degree of perplexity owing to its complex molecular structure. In biomedicine, it is utilized as a promising antiviral agent, as it mimics the nucleosides present in the viral genome itself, impeding its replication. The burstiness of its mechanism allows it to curb the proliferation of viruses such as hepatitis C and herpes simplex which can lead to severe medical complications. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) -4- (2- (trifluoromethoxy) ethoxy) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299280-93-4. Molecular formula: C48H54F3N6O8P. Mole weight: 930.95. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a phosphoramidite reagent frequently utilized in the synthesis of oligonucleotides. Despite its targeted applications in laboratory research, this molecule has not been clinically investigated for therapeutic purposes. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-20-8. Molecular formula: C46H53N6O7P. Mole weight: 832.92. | |
| D-?Ribitol, 1, ?4-?anhydro-?5-?O-? [bis (4-?methoxyphenyl) ?phenylmethyl] ?-?2-?O-?methyl-?1-?C-?phenyl-?, 3-?[2-?cyanoethyl N, ?N-?bis (1-?methylethyl)?phosphoramidite]?, (1S)?- | D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-1-C-phenyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], (1S)- is an indispensable phosphoramidite with application in oligonucleotide synthesis enabling the intricate modification and functionalization of nucleic acids. Synonyms: (2R, 3R, 4S, 5S)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-methoxy-5-phenyltetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1418182-88-3. Molecular formula: C42H51N2O7P. Mole weight: 726.84. | |
| D-?Ribitol, 1, ?4-?anhydro-?5-?O-?[bis (4-?methoxyphenyl) ?phenylmethyl]?-?2-?O-?methyl-?, 3-?[2-?cyanoethyl N, ?N-?bis (1-?methylethyl)?phosphoramidite] | D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite acting as a fundamental constituent in the intricate construction of oligonucleotides. Playing a crucial role in the modification of nucleic acids, it bestows researchers with the ability to delve into the complexities of RNA and DNA configurations. Synonyms: (2R, 3S, 4S)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1470023-72-3. Molecular formula: C36H47N2O7P. Mole weight: 650.74. | |
| dSpacer-CEP | dSpacer is used to introduce stable abasic sites in oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R, 3S) -2- ( (Bis (4-methoxyphenyl) (phenyl) methoxy) methyl) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grades: ≥95%. CAS No. 129821-76-7. Molecular formula: C35H45N2O6P. Mole weight: 620.71. | |
| Guanosine, 3'-?deoxy-?2'-?O-? (1, ?1-?difluoro-?2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?N-? (2-?methyl-?1-?oxopropyl) ?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-2-isobutyramido-9H-purin-9-yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96. | |
| Guanosine, 3'-?deoxy-?2'-?O-? (2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?N-? (2-?methyl-?1-?oxopropyl) ?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-2-isobutyramido-9H-purin-9-yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98. | |
| Guanosine, 3'-?deoxy-?2'-?O-?ethyl-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?N-? (2-?methyl-?1-?oxopropyl) ?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-ethyl-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-N- (2-methyl-1-oxopropyl) ?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a pivotal constituent, emanates as a linchpin in the explicit domain of nucleic acid synthesis, intently within DNA and RNA exploration. It confers enhanced prospects for manufacturing modified nucleotides as well as derivatives pertaining to nucleic acids, necessitated for investigations encompassing the structural, functional and behavioral attributes pertinent to DNA and RNA molecules, rendering significant insights. Synonyms: 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -4-ethoxy-5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite. CAS No. 2299279-11-9. Molecular formula: C45H57N8O7P. Mole weight: 852.96. | |
| Guanosine, 3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?N-? (2-?methyl-?1-?oxopropyl) ?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] serves as an indispensable compound within the biomedical sector, utilized for the synthesis of modified nucleotides. Its paramount importance lies in its significant contribution to the advancement of nucleic acid-based therapeutics, including antisense oligonucleotides, siRNAs and aptamers. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (6-benzamido-2-isobutyramido-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-17-1. Molecular formula: C46H57N8O7P. Mole weight: 864.97. | |
| Hexaethylene glycol phosphoramidite | Hexaethylene glycol phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 18-O-(4,4'-Dimethoxytrityl)-hexaethylene glycol-1-[[(2-cyanoethyl)-(N,N-diisopropyl)]- Phosphoramidite; 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite; Spacer 18 Phosphoramidite. Grades: ≥95.0%. CAS No. 125607-09-2. Molecular formula: C42H61N2O10P. Mole weight: 784.91. | |
| (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine | (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine, a sophisticated and multifunctional compound at the forefront of biomedical advancements, encompasses a pivotal role in the realm of biomedicine. It stands as an indispensable agent in the combat against an array of ailments. Synonyms: ( (2R, 3S, 5R)-5- (4-benzamido-2-oxopyrimidin-1 (2H)-yl)-3- (bis (4-methoxyphenyl) (phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; Cytidine,N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]. Grades: 95%. CAS No. 140712-83-0. Molecular formula: C46H52N5O9P. Mole weight: 849.91. | |
| N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite | N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used to incorporate nucleoside A into the synthesis of oligonucleotides. Synonyms: Bz-rA Phosphoramidite; DMT-2'O-TBDMS-Ra(Bz) Phosphoramidite; (2R, 3R, 4R, 5R) -5- (6-Benzamido-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( (tert-butyldimethylsilyl) oxy) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 98%. CAS No. 104992-55-4. Molecular formula: C53H66N7O8PSi. Mole weight: 988.22. | |
| N-Benzoyl-?5'-?O-?DMT-?2'-?O-[ (?triisopropylsilyl??oxy) methyl]-adenosine 3'-?CE phosphoramidite | N-Benzoyl-5'-O-DMT-2'-O-[ (?triisopropylsilyl??oxy) methyl]-adenosine 3'-CE phosphoramidite, a prominent element in the biomedical field, serves as a pharmaceutical asset for nucleic acid synthesis. Its paramount utility lies in facilitating drug innovation for adenosine receptor-focused therapies, pertinent to manifold conditions spanning from inflammatory ailments to cancerous manifestations and cardiovascular afflictions. Owing to its distinctive phosphoramidite framework, this agent augments nucleotide synthesis efficiency, thereby making considerable headway in the realm of medical exploration and experimentation. Synonyms: SCHEMBL6403564; (2R, 3R, 4R, 5R) -5- (6-Benzamido-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( ( (triisopropylsilyl) oxy) methoxy) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; (2R, 3R, 4R, 5R) -5- (6-Benzamido-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( ( (triisopropylsilyl) oxy) methoxy) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 220230-59-1. Molecular formula: C57H74N7O9PSi. Mole weight: 1060.3. | |
| Spacer Phosphoramidite 18 | Spacer phosphoramidites 18 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: >95% by HPLC. Molecular formula: C42H61N2O10P. Mole weight: 784.93. | |
| TFA-Hexylaminolinker Phosphoramidite | TFA-Hexylaminolinker Phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: TFA-aminolinker C6 phosphoramidite; 2-Cyanoethyl (6-(2,2,2-trifluoroacetamido)hexyl) diisopropylphosphoramidite; 6-(N-Trifluoroacetamido)hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: ≥90%. CAS No. 133975-85-6. Molecular formula: C17H31F3N3O3P. Mole weight: 413.42. | |
| T-(S)-GNA phosphoramidite | T-(S)-GNA phosphoramidite is a crucial building block in the synthesis of oligonucleotides used to treat various diseases such as cancer, viral infections, and genetic disorders. It is used to specifically modify the nucleotides of the oligonucleotide, enhancing its therapeutic potential and specificity. By utilizing this product, researchers can improve the efficacy and selectivity of their oligonucleotide-based therapies. Synonyms: (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; 1-[(S)-2-[[(Diisopropylamino)(2-cyanoethoxy)phosphino]oxy]-3-[(4,4'-dimethoxytrityl)oxy]propyl]thymine. Grades: ≥98%. CAS No. 168332-13-6. Molecular formula: C38H47N4O7P. Mole weight: 702.78. | |
| Uridine, 3'-?deoxy-?2'-?O-? (1, ?1-?difluoro-?2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Uridine, 3'-deoxy-2'-O- (1, ?1-difluoro-2-methoxyethyl) ?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a highly modified uridine purposed for RNA-based therapeutics. This dynamically intricate compound has proven effects on genetic diseases such as cystic fibrosis, Huntington's disease, and Duchenne muscular dystrophy by virtue of its unique stability and specificity. By its design, Uridine, 3'-deoxy-2'-O- (1, ?1-difluoro-2-methoxyethyl) ?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is an exceptional representation of the progress seen in RNA-targeted drugs. Synonyms: ((2R,3S,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-53-9. Molecular formula: C41H50F2N5O8P. Mole weight: 809.84. | |
| Uridine, 3'-?deoxy-?2'-?O-? (2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Uridine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a fundamental compound with utilization pertaining to the synthesis of nucleotide analogs and nucleic acids, embodying a crucial role in the developmrnt of antiviral therapies and gene modulation. Synonyms: 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite. CAS No. 2299277-80-6. Molecular formula: C41H52N5O8P. Mole weight: 773.85. | |
| Uridine, 3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Uridine, 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], a chemical reagent employed in RNA analog synthesis, has garnered attention as an effective treatment for viral infections such as HIV and hepatitis C. Its synthetic properties mimic those of natural uridine nucleotides, enabling the development of RNA molecules with greater therapeutic efficacy. Its efficient and specific incorporation into RNA oligonucleotides via phosphoramidite conjugation makes it a valuable tool in drug design. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-38-6. Molecular formula: C41H50N5O7P. Mole weight: 755.84. | |
| Uridine, 3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?[2-? (trifluoromethoxy) ?ethyl]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Uridine 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-[2-(trifluoromethoxy)ethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a crucial component employed in biomedical research to construct oligonucleotides, whose effects are far-reaching. Not only do these oligonucleotides show promise in inhibiting the proliferation of potentially deadly viruses, but they also hold potential as cancer cell treatments and may even have an impact on protein expression. Synonyms: 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) -4- (2- (trifluoromethoxy) ethoxy) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite. CAS No. 2299280-34-3. Molecular formula: C41H49F3N5O8P. Mole weight: 827.83. | |
| Uridine, 3'-?deoxy-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Uridine, 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is an essential chemical compound utilized in nucleoside analogue development to combat viral diseases and cancer. Interestingly, this natural building block is employed to synthesize oligonucleotides that can specifically target genes or viral RNA. Uridine derivatives perform a crucial role in improving the pharmacokinetic and pharmacological properties of nucleoside analogs, thereby enhancing their therapeutic efficacy to combat lethal illnesses. Synonyms: 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite. CAS No. 329773-19-5. Molecular formula: C39H48N5O7P. Mole weight: 729.8. | |
| Uridine, 5'-?O-? [bis (4-?methoxyphenyl) ?phenylmethyl] ?-?2'-?O-?methyl-?3'-?thio-?, 3'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Uridine, the 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-3'-thio nucleotide analog, is a vital component in the synthesis of both RNA and DNA within the biomedical industry. Additionally, its applications extend to antiviral drug research and treatment of HIV-1, thereby highlighting its multifaceted nature in the realm of biomedicine. Synonyms: (2R, 3R, 4R, 5R)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 247223-84-3. Molecular formula: C40H49N4O8PS. Mole weight: 776.88. | |
| Uridine, 5'-?O-? [bis (4-?methoxyphenyl) ?phenylmethyl] ?-?3-?methyl-?2'-?O-?methyl-?, 3'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Uridine 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3-methyl-2'-O-methyl-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) finds utility as a phosphoramidite constituent in the construction of distinct DNA sequences for investigative purposes. Uridine analogues, including the aforementioned derivative, have been explored for therapeutic uses against a spectrum of neurological and psychiatric maladies, hence providing an avenue for potential drug discovery. Synonyms: (2R, 3R, 4R, 5R)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-methoxy-5- (3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 911836-90-3. Molecular formula: C41H51N4O9P. Mole weight: 774.84. | |
| Zebularine 3'-CE phosphoramidite | Zebularine 3'-CE phosphoramidite is a key compound widely used in biomedical field playing a crucial role in the synthesis of oligonucleotides and specifically designed for the modification of nucleic acids. It enables the research of various diseases, including cancer, by targeting specific gene sequences and regulating gene expression. Synonyms: Zebularine CEP; 155831-90-6; 2/'-O-T-BUTYLDIMETHYLSILYL-3/'-O-[(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINO]-5/'-O-(4,4/'-DIMETHOXY; 3-[[ (2R, 3R, 4R, 5R) -2-[[bis (4-methoxyphenyl) -phenylmethoxy]methyl]-4-[tert-butyl (dimethyl) silyl]oxy-5- (2-oxopyrimidin-1-yl) oxolan-3-yl]oxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile; W-201408; (2R, 3R, 4R, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (2-oxopyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 95%. CAS No. 155831-90-6. Molecular formula: C45H61N4O8PSi. Mole weight: 845.04. | |
| DyLight 5 CEP | DyLight 5 CEP is a fluorescent dye used for oligonucleotide labeling. Synonyms: 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropylphosphoramidityl]propyl]-3,3,3',3'-tetramethylindodicarbocyanine chloride; Cyanine 5 Phosphoramidite. Grades: ≥85.0%. CAS No. 182873-67-2. Molecular formula: C60H72N4O4PCl. Mole weight: 979.68. | |
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