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| Product | Description | |
|---|---|---|
| 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite | 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite, a critical chemical reagent in the biomedicine industry, demonstrates immense value for the synthesis of nucleosides and nucleotides. Its pivotal role lies within the realm of research and development of pharmaceuticals, particularly anti-cancer and antiviral drugs. CAS No. 2376756-54-4. Molecular formula: C43H52FN8O6P. Mole weight: 826.9. |  |
| 2-cyanoethyl (((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite | 2-cyanoethyl (((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite, a critical component within the biomedical industry, exhibits remarkable significance. Serving as an essential foundational unit for the synthesis of nucleoside phosphoramidites and diverse bioactive compounds, this compound profoundly impacts the realm of drug discovery, particularly towards the development of innovative antiviral and anticancer agents. CAS No. 182935-50-5. Molecular formula: C38H45FN5O6P. Mole weight: 717.77. | |
| 2-cyanoethyl (((2S,3R,4R,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite | 2-cyanoethyl (((2S,3R,4R,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite exhibits paramount significance within the biomedical industry. It serves as a vital ingredient in oligonucleotide synthesis for multifarious applications encompassing gene expression analysis, antisense technology, and the pioneering sector of drug development. CAS No. 2376756-55-5. Molecular formula: C44H55N8O7P. Mole weight: 838.93. | |
| 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite | 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite, a remarkable biomedicine agent, serves as a pivotal component in the synthesis of diverse therapeutic agents that effectively combat diseases of distinct etiologies, including cancer and neurodegenerative disorders. Leveraging its profound chemical prowess and efficacy, this invaluable entity propels the frontiers of pharmaceutical research and development, facilitating the innovation of novel bioactive compounds with promising therapeutic potential. As it attains precise and expeditious chemical synthesis, this indispensable product impels the progress of biomedicine to unprecedented heights. Synonyms: 2-Cyanoethyl((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite; [(2R)-3-(2-cyanoethyl)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy-[di(propan-2-yl)amino]phosphinite. CAS No. 1772522-16-3. Molecular formula: C38H66N2O3P-. Mole weight: 629.9. | |
| (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite, an indispensable phosphoramidite reagent, demonstrates immense significance within the realm of biomedicine. Its role primarily revolves around its extensive utilization in synthesizing oligonucleotides for a diverse range of crucial applications. These include the fields of gene therapy, molecular diagnostics, and antisense therapy. CAS No. 1797762-50-6. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is an intricate and versatile compound in the realm of biomedical research. Its utilization lies predominantly in the synthesis of nucleotides and nucleic acids, catering to an array of molecular biology and drug discovery applications. This product can serve as a paramount resource for drug development investigations, gene expression analysis, and genetic scrutiny. CAS No. 252770-65-3. Molecular formula: C40H47FN7O6P. Mole weight: 771.82. | |
| ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite | ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite is a fundamental reagent for the synthesis of augmented nucleosides and oligonucleotides. This phosphoramidite compound plays a crucial role in facilitating research on therapeutic strategies associated with a variety of diseases, be it viral infections, hereditary diseases, or even the malignant ravages of cancer. CAS No. 2376756-43-1. Molecular formula: C46H50FN8O5P. Mole weight: 844.91. | |
| Bis(2-cyanoethyl) diisopropylphosphoramidite | Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Group: Signaling pathways. CAS No. 102690-88-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-24126. |  |
| Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite | A useful phosphorylating reagent. Synonyms: N,N-bis(1-Methylethyl)phosphoramidous acid bis(2-cyanoethyl) ester; Bis(2-cyanoethyl) diisopropylphosphoramidite; Bis(2-cyanoethoxy)(diisopropylamino)phosphine; Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine; Phosphoramidous acid, bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Bis-cyanoethyl-N,N-diisopropyl CED phosphoramidite. Grade: 96%. CAS No. 102690-88-0. Molecular formula: C12H22N3O2P. Mole weight: 271.30. | |
| Dibenzyl N,N-diisopropylphosphoramidite | Dibenzyl diisopropylphosphoramidite is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 108549-23-1. Pack Sizes: 10 g; 25 g. Product ID: HY-W013777. | |
| Dibenzyl-N,N-diisopropylphosphoramidite | Dibenzyl-N,N-diisopropylphosphoramidite. CAS No: 108549-23-1 |  Sarchem Laboratories New Jersey NJ |
| Di-tert-butyl diisopropylphosphoramidite | Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Group: Signaling pathways. CAS No. 137348-86-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W009354. | |
| 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione | 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-threo-pentofuranose; (2R,3S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-ara-dU Phosphoramidite; 5'-O-DMTr-3'-deoxyuridine ara-2'-phosphoramidite. Grade: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79. | |
| 2',3'-ddA(N-Bz) CE Phosphoramidite | 2',3'-ddA(N-Bz) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyadenosine (ddA) with an N-benzoyl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddA(N-Bz) Phosphoramidite; 2',3'-Dideoxyadenosine (N-bz) 5'-phosphoramidite; N6-Benzoyl-2',3'-dideoxyadenosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-ddA(Bz) CE Phosphoramidite; ((2S,5R)-5-(6-Benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C26H34N7O4P. Mole weight: 539.58. | |
| 2',3'-ddG(N-dmf) CE Phosphoramidite | 2',3'-ddG(N-dmf) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyguanosine (ddG) with an N-dimethylformamidine (N-dmf) protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddG(N-dmf) Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite; N2-Dimethylaminomethylidene-2',3'-dideoxyguanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-Dideoxyguanosine (N-DMF) 5'-phosphoramidite; 2',3'-ddG(DMF) CE Phosphoramidite. Grade: ≥97%. Molecular formula: C22H35N8O4P. Mole weight: 506.55. | |
| 2',3'-ddG(N-iBu) CE Phosphoramidite | 2',3'-ddG(N-iBu) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyguanosine (ddG) with an N-isobutyryl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddG(N-iBu) Phosphoramidite; N2-Isobutyryl-2',3'-dideoxyguanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-Dideoxyguanosine (N-iBu) 5'-phosphoramidite; 2',3'-ddG(iBu) CE Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C23H36N7O5P. Mole weight: 521.56. | |
| 2',3'-ddT CE Phosphoramidite | 2',3'-ddT CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxythymidine (ddT). This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddT Phosphoramidite; 2',3'-Dideoxythymine 5'-phosphoramidite; 2',3'-Dideoxythymine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-ddT 5'-CE Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C19H31N4O5P. Mole weight: 426.45. | |
| 2,?4(1H,?3H)?-?Pyrimidinedione, 1-?[5-?O-?[[bis(1-?methylethyl)?amino]?(2-?cyanoethoxy)?phosphino]?-?2,?3-?dideoxy-?2-?fluoro-?3-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?β-?D-?arabinofuranosyl]?-?5-?methyl- | The biochemical 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-2-fluoro-3-[[(4-methoxyphenyl)diphenylmethyl]amino]-β-D-arabinofuranosyl]-5-methyl-, is well known in the biomedical realm due to its anticancer effects, serving as a therapeutic agent for acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma by impeding DNA synthesis and obstructing the propagation and dissemination of malignant cancerous cells, thereby proving to be an indispensable asset. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 329773-25-3. Molecular formula: C39H47FN5O6P. Mole weight: 731.79. | |
| 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite | 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a critical and widely used biochemical reagent in the biomedicine industry. Its primary function is to aid in the synthesis of RNA oligonucleotides needed for various research purposes, including the development of therapeutic oligonucleotides that target specific genetic disorders. Moreover, it serves as a fundamental tool for exploring the chemical modification of RNA molecules and its impact on different biological processes. Its significance in the biomedicine industry cannot be overstated. Synonyms: (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-5-vinyl-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 287980-24-9. CAS No. 287980-24-9. Molecular formula: C41H49N4O8P. Mole weight: 756.8. | |
| 2-O-DMT-sulfonyldiethanol phosphoramidite | 2-O-DMT-sulfonyldiethanol phosphoramidite substantiates its inevitable prowess in the synthesis and alteration of nucleic acids across diverse applications. Unparalleled in its chemical composition, this exceptional concoction facilitates meticulous and efficient manipulation of nucleic acids, thus fostering elevated biomedical exploration with incomparable precision. Synonyms: 2-((2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)sulfonyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl]sulfonyl]ethyl 2-cyanoethyl ester; 2-[2-(4,4'-dimethoxytrityloxy)ethylsulfonyl]ethyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 2-O-DMT-S phosphoramidite; 5'-Phosphate-Amidite; O-DMT-2,2'-sulfonyldiethanol phosphoramidite; 5'-Phosphate-ON Reagent. Grade: >95% by HPLC. CAS No. 108783-02-4. Molecular formula: C34H45N2O7PS. Mole weight: 656.77. | |
| 2-O-MOE-Spacer Phosphoramidite | 2-O-MOE-Spacer Phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides, incorporating a 2'-O-methoxyethyl (MOE) modification on the ribose sugar. The MOE modification enhances the stability, nuclease resistance, and hybridization properties of the oligonucleotide, improving its performance in biological applications. The spacer refers to a chemical linker that separates the modified nucleoside from the rest of the oligonucleotide chain, often used to introduce flexibility or to provide a region for further functionalization, such as conjugation to other molecules like drugs, probes, or proteins. The phosphoramidite group at the 5'-position allows for the incorporation of this modified nucleotide into the growing oligonucleotide chain during synthesis. This phosphoramidite is useful for creating oligonucleotides with enhanced properties, such as improved cellular uptake, stability, and functionality, in applications like antisense therapy, RNA-based therapeutics, or gene editing. Synonyms: (2R,3S,4S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5-O-DMT-2-O-MOE-D-Ribose 3-CE phosphoramidite; DMT-2'-O-MOE-D-Ribitol phosphoramidite; 5'-O-DMTr-2'-O-MOE-3'-Phosphoramidite; Abasic 2'-O-MOE amidite; DMT-2'-O-MOE-D-Ribitol 3-CE phosphoramidite. Grade: ≥95%. CAS No. 2934665-30-0. Molecular formula: | |
| 2'-OTBS N3-Me-U amidite | 2'-OTBS N3-Me-U amidite is a vital compound used in the field of biomedicine. With its therapeutic properties, this product is utilized for the development of targeted drugs catering to specific drug delivery systems, gene therapy, and immunotherapy. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-3-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; N3-Methyl Uridine CED phosphoramidite. Grade: >95%. CAS No. 179762-50-6. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite | 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite: This phosphoramidite derivative is essential in the biomedical industry for synthesizing modified RNA molecules. It acts as a building block during solid-phase RNA synthesis, enabling the introduction of 2'-O-tert-butyldimethylsilyl, 5'-O-DMT, and C2-methyladenosine modifications. This phosphoramidite facilitates research on RNA structure-function relationships, post-transcriptional modifications, and drug discovery targeting diseases like cancer and viral infections. Synonyms: (2R,3R,4R,5R)-5-(6-Amino-2-methyl-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1028723-99-0. Molecular formula: C47H64N7O7Si. Mole weight: 867.14. | |
| 2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite | 2'-tBDSilyl Adenosine (n-PAC) CED Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It incorporates a 2'-tert-butyldimethylsilyl (tBDSilyl) group onto the adenosine (A) nucleoside at the 2'-position. Additionally, it features a nitrilotriacetic acid (n-PAC) group for chelating metal ions and a controlled-efficiency (CED) phosphoramidite for efficient incorporation during solid-phase synthesis. This reagent enables the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies. Synonyms: PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Pac-A-CE phosphoramidite; rA (Pac) CE-Phosphoramidite; 2'-TBDMS Adenosine (n-PAC) CED phosphoramidite. Grade: 95%. CAS No. 121058-86-4. Molecular formula: C54H68N7O9PSi. Mole weight: 1018.22. | |
| 3'-NH-Tr-2',3'-ddA(Bz)-5'-CE-Phosphoramidite | 3'-NH-Tr-2',3'-ddA(Bz)-5'-CE-Phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis, particularly for introducing specific modifications into DNA sequences. Overall, this phosphoramidite can be used in custom oligonucleotide synthesis, where modifications like chain termination, functionalization, or base protection are required. Synonyms: Adenosine, N-benzoyl-2',3'-dideoxy-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Adenosine, N-benzoyl-2',3'-dideoxy-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Benzoyl-3'-(trityl)amino-2',3'-dideoxyadenosine-5'-cyanoethyl phosphoramidite; ((2S,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; 3'-Tritylamino-N6-benzoyl-2',3'-dideoxyadenosine-5'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite. Grade: ≥95%. CAS No. 195375-64-5. Molecular formula: C45H49N8O4P. Mole weight: 796.90. | |
| 3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite | 3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite is a specialized phosphoramidite compound used in the synthesis of oligonucleotides, specifically designed for creating modified nucleic acids with potential applications in molecular biology and medicine. Synonyms: Cytidine, N-benzoyl-2',3'-dideoxy-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; ((2S,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; N4-Benzoyl-3'-(trityl)amino-2',3'-dideoxycytidine-5'-cyanoethyl Phosphoramidite; N4-Benzoyl-3'-(trityl)amino-2', 3'-dideoxycytidine 5'-(2-cyanoethyl N,N-diisopropylphosphoramidite). Grade: ≥97%. CAS No. 195375-65-6. Molecular formula: C44H49N6O5P. Mole weight: 772.87. | |
| 3'-NH-Tr-2',3'-ddT-5'-CE-phosphoramidite | 3'-NH-Tr-2',3'-ddT-5'-CE-Phosphoramidite is a specific phosphoramidite compound used in the synthesis of oligonucleotides and nucleic acid analogs. Phosphoramidites are key intermediates in the chemical synthesis of nucleic acids, playing a crucial role in creating modified DNA or RNA strands that have various applications in molecular biology, biotechnology, and medicine. Synonyms: Thymidine, 3'-deoxy-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Thymidine, 3'-deoxy-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 3'-(Trityl)amino-2',3'-dideoxythymidine-5'-cyanoethyl phosphoramidite; 2-Cyanoethyl (((2S,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite; 3-TRNH-DT-5-CEPA; 3'-NH-trityl-3'-aminothymidine 5'-O-cyanoethyl-N,N-diisopropylaminophosphoramidite. Grade: ≥95%. CAS No. 195375-68-9. Molecular formula: C38H46N5O5P. Mole weight: 683.78. | |
| 3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite | TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement. Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite. Grade: 98%. CAS No. 325683-96-3. Molecular formula: C45H50N5O8P. Mole weight: 819.90. | |
| 5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite | 5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite, a bio-molecular tool, facilitates the integration of 5-aza-2'-deoxycytidine into oligonucleotides. This inhibits DNA methyltransferase and affords therapeutic benefits such as anti-cancer activity. The phosphoramidite reagent is a research asset that enables differential and accurate DNA sequence modification for targeted epigenetic investigation. It thus contributes to newer approaches in therapeutic interventions. Synonyms: (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-oxo-4-(2-phenoxyacetamido)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 929904-98-3. CAS No. 929904-98-3. Molecular formula: C46H53N6O9P. Mole weight: 864.92. | |
| 5'-DMT-2'-O-TBDMS-rU Phosphoramidite | 5'-DMT-2'O-TBDMS-rU Phosphoramidite is a classic 2-OTBDMS phosphoramidite used to incorporate U into synthetic oligonucleotides. Synonyms: rU Phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DMT-2'-O-TBDMS-rU Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite; 5'-DMT-2'-O-TBDMS-Uridine Phosphoramidite; DMT-2'-O-TBDMS-U-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-uridine-3'-cyanoethyl Phosphoramidite. Grade: ≥97%. CAS No. 118362-03-1. Molecular formula: C45H61N4O9PSi. Mole weight: 861.04. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite, a highly valued compound within the biomedicine sector, plays a pivotal role in the synthetic production of altered nucleic acids. Primarily employed as a fundamental unit during oligonucleotide formation, it showcases tremendous potential in advancing RNA-based therapeutic interventions. Through its exceptional capability, this product empowers precise and effective nucleoside modification, enabling targeted remedies for an array of prevalent ailments including viral afflictions and hereditary anomalies. Synonyms: 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. CAS No. 875302-47-9. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite, an indispensable compound in the thriving biomedical sector, serves as a pivotal component for oligonucleotide synthesis. This ground-breaking technique unlocks unparalleled potential to combat a myriad of afflictions encompassing cancer, viral infections, and genetic aberrations. Synonyms: 5'-DMT-3'-O-TBDMS-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-Hexynyl CE Phosphoramidite | 5'-Hexynyl CE Phosphoramidite, an essential reagent in biomedical research for oligonucleotide synthesis, offers versatility in sequencing modification through its alkyne functionality, enabling conjugation with diverse biomolecules. The reagent presents vast potential in critical fields such as gene therapy, drug discovery, and disease diagnosis and management. Its unique characteristics position it as a promising asset in achieving complex nucleotide sequencing, furthering our understanding of genetic health and disease. Synonyms: 2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite; 5-Hexyn-1-yl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Grade: 95%. CAS No. 1048985-37-0. Molecular formula: C15H27N2O2P. Mole weight: 298.37. | |
| 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(methyl-N,N-diisopropyl)phosphoramidite | dA(Bz)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for specialized oligonucleotide synthesis. The adenine base is protected with a benzoyl (Bz) group at the N6 position to prevent side reactions during synthesis. At the 3' position, the methoxy group replaces the standard hydroxyl group, providing unique structural properties and increased chemical stability to the oligonucleotide. The phosphoramidite functionality ensures efficient incorporation into oligonucleotide chains via automated synthesis. This modification is particularly useful in applications requiring oligonucleotides with altered backbone properties, improved hybridization characteristics, or enhanced resistance to enzymatic degradation, such as in therapeutic nucleic acids and molecular biology studies. Synonyms: dA(Bz)-3'-Methoxy Phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Me phosphonamidite; (2R,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite; 2'-Deoxy Adenosine (n-Bz) methyl phosphoramidite; DNA A(Bz) OMe-amidite; dA(Bz) OMe-amidite. Grade: ≥98%. CAS No. 84416-82-0. Molecular formula: C45H51N6O7P. Mole weight: 818.90. | |
| 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite | 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine. Grade: ≥95%. CAS No. 109389-30-2. Molecular formula: C39H47N4O8P. Mole weight: 730.80. | |
| 5'-O-DMT-2'-O-(2-Methoxyethyl)-5-methyluridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite can introduce uridine units into the building blocks of non-natural DNA and RNA chains. Synonyms: 5'-O-(4,4'-Dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-yl]-2-cyanoethyl-N,N'-diisopropylphosphoramidite; 5'-O-DMT-2'-MOE-thymidine 3'-CE phosphoramidite; DMT-2'-O-MOE-T-CEP; 5-Me-DMT-2'-O-MOE-U-CE P; DMT-2'-O-MOE-T-CE-Phosphoramidite; 5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl Phosphoramidite; 5'-O-DMT-2'-O-MOE-MeU 3'-CE phosphoramidite; 2'-O-MOE-5MeU-3'-phosphoramidite. Grade: ≥98% by HPLC. CAS No. 163878-63-5. Molecular formula: C43H55N4O10P. Mole weight: 818.89. | |
| 5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a phosphoramidite derivative used for the solid-phase research and development of modified RNA sequences. With its 5'-O-DMT protection, 2'-O-TBDMS modification and 2-thiouridine incorporation, it enables the controlled research and development of RNA molecules for studying RNA-protein interactions and RNA-based therapeutics targeting diseases like cancer and viral infections. Synonyms: 2'-OTBS 2-Thio-U amidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: >95%. CAS No. 163496-21-7. Molecular formula: C45H61N4O8PSSi. Mole weight: 877.11. | |
| 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite | 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite is a specialized phosphoramidite used for the synthesis of oligonucleotides. It includes a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 3'-tert-butyldimethylsilyl (TBDMS) group for 3'-hydroxyl protection, and an N2-isobutyryl group to protect the exocyclic amine of the guanine base. Additionally, it has a cyanoethyl (CE) group at the 2'-position of the phosphoramidite. These protective groups help facilitate efficient synthesis and stability of the oligonucleotides, making this compound valuable for research, diagnostic, and therapeutic applications. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite; (2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-TBDMS-ibu-rG Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N2-iBu-rG CED phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥95%. CAS No. 1445905-51-0. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs. Synonyms: N4-Benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite; dC(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 102212-98-6. Molecular formula: C46H52N5O8P. Mole weight: 833.93. | |
| 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite | 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite is a modified phosphoramidite used in solid-phase oligonucleotide synthesis. This compound is used for the preparation of custom oligonucleotides, such as for DNA sequencing, gene synthesis, or other nucleic acid-based applications. The L-configuration of the sugar in the name may imply a chiral modification, which could influence the nucleic acid's properties in certain contexts. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-L-erythro-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3R,5S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; L-DNA T amidite; beta-L-dT-CE Phosphoramidite; 5'-Dimethoxytrityl-beta-L-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-O-DMTr-L-dT-3'-CED phosphoramidite. Grade: ≥95%. CAS No. 141846-55-1. Molecular formula: C40H49N4O8P. Mole weight: 744.83. | |
| 5'-Thiol-Modifier C6 | 5'-Thiol-Modifier C6, a biomedical agent, serves as a transformative tool for DNA sequence modification, gear towards tailor-made treatment of neoplastic disorders, viral contagions, as well as genetic anomalies. By minimizing harm to healthy cells while directing medicines to diseased cells, its role in therapeutic regimes for cancer, viral infections, and genetics is eminent and valuable. Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(triphenylmethyl)thio]hexyl ester; 2-Cyanoethyl 6-[(triphenylmethyl)thio]hexyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 6-[(triphenylmethyl)thio]hexyl ester; 2-cyanoethyl (6-(tritylthio)hexyl) diisopropylphosphoramidite; S-Trityl-6-mercaptohexyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N,N-Diisopropylamide phosphorous acid (2-cyanoethyl)[6-(tritylthio)hexyl] ester; Tr-Thio-C6-linker amidite; 5' Thio C6 Modifier; Trityl-6-Thiohexyl Amidite; 5'-Thiol (S-Trityl)-hexyl-C6-Modifier phosphoramidite; 5'-Thiol (S-Trityl)-hexyl-C6-Modifier (2-cyanoethyl)-(N,N-diisopropyl)-Phosphoramidite; 5'-Thiol (S-Trityl)-hexyl-C6-Modifier; 5'-Thiol Modifier Hexyl CED phosphoramidite. CAS No. 116919-17-6. Molecular formula: C34H45N2O2PS. Mole weight: 576.78. | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-dG(ibu) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6,8-dioxo-1,6,7,8-tetrahydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DNA 8-oxo-G(iBu) amidite. Grade: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a cutting-edge and highly effective modified nucleoside utilized in advanced biomedical research. With a distinctive and intricate chemical arrangement, it possesses unparalleled potential in gene therapies and drug delivery systems. This nucleoside has shown promising outcomes in the treatment and study of various genetic disorders and diseases, including cancer. Its exceptional stability and efficiency are beneficial in advancing research in these fields. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-70-0. Molecular formula: C49H55F2N8O7P. Mole weight: 936.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a potent phosphoramidite recompound widely employed for the research of modified oligonucleotides, particularly in the development of nucleotide-based drugs targeting specific diseases such as cancer, viral infections and genetic disorders. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-93-1. Molecular formula: C49H57N8O7P. Mole weight: 901. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?ethyl-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an imperative compound, finding extensive application for oligonucleotide drugs research. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-ethoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-74-1. Molecular formula: C48H55N8O6P. Mole weight: 870.97. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional compound used in the research of formidable malignancies, such as lymphoma and leukemia. Its utilization in the pursuit of innovative antiviral therapeutics that specifically target RNA viruses denotes its indispensable role. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(6-benzamido-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299282-94-1. Molecular formula: C49H55N8O6P. Mole weight: 882.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a complex chemical entity employed in the synthesis of oligonucleotides targeting viral infections and various cancers. The versatility of this remarkable molecule extends beyond biomedical research and treatment; it has the potential to alter genetic sequences, thereby opening new therapeutic avenues for myriad hitherto enigmatic human ailments. Its designation as a universally valuable synthetic building block in both academic and clinical milieus underscores its indispensability in biomedicine. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-22-0. Molecular formula: C47H53N8O6P. Mole weight: 856.95. | |
| Beta-D-homoDNA-C(Bz) Phosphoramidite | Beta-D-homoDNA C(Bz) Phosphoramidite is a reagent used in the synthesis of oligonucleotides containing modified nucleotides known as beta-D-homoDNA, where the sugar backbone is altered to include an additional carbon atom, leading to an extended structure compared to regular DNA. This specific phosphoramidite incorporates a cytosine (C) base with a benzoyl (Bz) protecting group on the exocyclic amino group, which helps prevent undesired reactions during synthesis. The modification in the sugar backbone (beta-D-homoDNA) provides increased stability and unique binding properties, making it valuable for applications in molecular biology, diagnostics, and therapeutic research. Synonyms: Benzamide, N-[1-[6-O-[bis(4-methoxyphenyl)phenylmethyl]-4-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-β-D-erythro-hexopyranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-, (S)-; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[1-[6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-β-D-erythro-hexopyranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide, (S)-; (2R,3S,6R)-6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydro-2H-pyran-3-yl (2-cyanoethyl) (S)-diisopropylphosphoramidite. Grade: ≥98%. CAS No. 145610-77-1. Molecular formula: C47H54N5O8P. Mole weight: 847.94. | |
| Biotin-dT CE-Phosphoramidite | Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques. Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT. Grade: 95%. CAS No. 198080-40-9. Molecular formula: C69H89N8O12PS. Mole weight: 1285.55. | |
| Biotin Phosphoramidite | Biotin Phosphoramidite is a reagent used to incorporate biotin into oligonucleotides during solid-phase synthesis. The biotin moiety, known for its strong affinity to streptavidin, allows for easy detection, purification, and immobilization of the modified oligonucleotides. This makes it a valuable tool in molecular biology for labeling, assays, and targeted delivery applications. Biotinylated oligonucleotides are commonly used in techniques such as ELISA, Western blotting, and nucleic acid hybridization, providing a versatile and efficient way to enhance the functionality of DNA and RNA sequences. Synonyms: 1-Dimethoxytrityloxy-2-(N-biotinyl-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl ester; 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[Bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Biotin-amidite; DMTr-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥96%. CAS No. 1217500-22-5. Molecular formula: C46H64N5O8PS. Mole weight: 878.07. | |
| Cytidine, N-?acetyl-?5'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?N-?methyl-?, 3'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional and multifarious pharmaceutical compound. With its distinctive chemical configuration, this exquisite compound exerts effects in research of a range of maladies including cancers and viral infections. Synonyms: 2'-OTBS C(Me,Ac) amidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-(N-methylacetamido)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-N4-methyl cytidine 3'-CED phosphoramidite. Grade: >95%. CAS No. 1253796-11-0. Molecular formula: C48H66N5O9PSi. Mole weight: 916.12. | |
| Cytidine, N-?benzoyl-?2',?3'-?dideoxy-?2'-?fluoro-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-2',3'-dideoxy-2'-fluoro-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a paramount pharmacological compound, exhibiting remarkable proficiency in facilitating the intricate research and development of perturbed nucleoside analog. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 182934-57-2. Molecular formula: C45H50FN6O6P. Mole weight: 820.89. | |
| Cytidine, N-?benzoyl-?2',?3'-?dideoxy-?5-?methyl-?3'-?[(triphenylmethyl)?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-2',3'-dideoxy-5-methyl-3'-[(triphenylmethyl)amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a crucial compound used in the biomedical industry for synthesizing modified nucleotides. It plays a vital role in the creation of nucleotide analogs utilized in antiviral and anticancer drug development. This product ensures precise incorporation of modified nucleotides during DNA or RNA synthesis. Synonyms: ((2S,3S,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 195375-70-3. Molecular formula: C45H51N6O5P. Mole weight: 786.9. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleotide analog that has shown promising results as an effective option for treating a wide range of life-threatening illnesses, including cancer, viral infections, and genetic disorders. Its remarkable capability to limit or obstruct the activity of pathological genes and proteins fills it with potential to revolutionize the biomedical sector. With its unique properties, this molecule could be the answer to targeted therapy and fulfill the growing need for a disease-specific cure. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-56-2. Molecular formula: C48H55F2N6O8P. Mole weight: 912.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-2'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((tert-butyldimethylsilyl)oxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional bioactive compound extensively applied in the biomedical domain, exhibiting unparalleled potency in studying diverse pathological conditions, predominantly those associated with intricate RNA metabolism and gene expression modulation. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-82-8. Molecular formula: C48H57N6O8P. Mole weight: 876.98. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a key ingredient in the synthesis of antisense oligonucleotides (ASOs), which facilitate the mitigation or remediation of diseases by specifically targeting genes or proteins implicated in disease pathogenesis. MMEDIATELY upon its incorporation into the ASO production process, Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] effects a robust increase in the fidelity and specificity of the synthesized ASOs. Clinical applications of ASOs incorporating Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] range from the attenuation or eradication of neoplastic lesions to remarkable amelioration of chronic viral syndromes and other genetic maladies. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-53-5. Molecular formula: C48H55N6O7P. Mole weight: 858.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?[2-?(trifluoromethoxy)?ethyl]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-[2-(trifluoromethoxy)ethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic compound with a high degree of perplexity owing to its complex molecular structure. In biomedicine, it is utilized as a promising antiviral agent, as it mimics the nucleosides present in the viral genome itself, impeding its replication. The burstiness of its mechanism allows it to curb the proliferation of viruses such as hepatitis C and herpes simplex which can lead to severe medical complications. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)-4-(2-(trifluoromethoxy)ethoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299280-93-4. Molecular formula: C48H54F3N6O8P. Mole weight: 930.95. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a phosphoramidite reagent frequently utilized in the synthesis of oligonucleotides. Despite its targeted applications in laboratory research, this molecule has not been clinically investigated for therapeutic purposes. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-20-8. Molecular formula: C46H53N6O7P. Mole weight: 832.92. | |
| dC(Ac)-CE-Reverse Phosphoramidite | dC(Ac)-CE-Reverse Phosphoramidite is a cytidine-derived phosphoramidite designed for the reverse incorporation of nucleotides during oligonucleotide synthesis. It features a 3'-cyanoethyl (CE) phosphoramidite group at the 5'-position, enabling the addition of nucleotides in the reverse (3'→5') direction instead of the conventional 5'→3' direction. The cytosine base is protected with an acetyl (Ac) group at the N4 position to prevent side reactions during synthesis. This reverse phosphoramidite is commonly used for specialized oligonucleotide designs, such as branched structures, probes, and complex synthetic constructs, where reverse polarity is required for functionality or stability. Synonyms: 3'-DMT-dC(Ac)-CE Reverse; Cytidine, N-acetyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Acetyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-5'-cyanoethyl phosphoramidite; ((2R,3S,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; 3'-O-DMTr-dC(Ac)-CE-Reverse-Phosphoramidite; DNA C(Ac) 3'-DMTr 5'-amidite. Grade: ≥98%. CAS No. 1632243-18-5. Molecular formula: C41H50N5O8P. Mole weight: 771.84. | |
| Desthiobiotin TEG CE Phosphoramidite | Desthiobiotin TEG CE Phosphoramidite is a chemical used in the synthesis of oligonucleotides. It contains a desthiobiotin group attached to a TEG linker with a CE phosphoramidite moiety. This product is commonly used in affinity chromatography to selectively bind avidin or streptavidin proteins, and for applications in protein purification, drug delivery, and diagnostics. Synonyms: Desthiobiotin TEG Phosphoramidite; 1,1-Bis(4-methoxyphenyl)-25-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-20-oxo-1-phenyl-2,6,9,12,15-pentaoxa-19-azapentacosan-4-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: >95% by HPLC. Molecular formula: C52H78N5O11P. Mole weight: 980.19. | |
| DesthiobiotinTEG Phosphoramidite | DesthiobiotinTEG Phosphoramidite is a vital tool in molecular biology for the synthesis of labeled oligonucleotides. By incorporating this innovative phosphoramidite during DNA synthesis, researchers can generate biotinylated oligonucleotides lacking the intrinsic biotin-avidin affinity. This product is highly beneficial for applications such as DNA labeling is affinity chromatography and bioconjugation for studying biomolecular interactions. Synonyms: 1-Dimethoxytrityloxy-3-O-(N-desthiobiotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 1,1-bis(4-methoxyphenyl)-25-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-20-oxo-1-phenyl-2,6,9,12,15-pentaoxa-19-azapentacosan-4-yl (2-cyanoethyl) diisopropylphosphoramidite. Molecular formula: C52H78N5O11P. Mole weight: 980.19. | |
| DMT-2'-F-dC(dmf)-CE-Phosphoramidite | DMT-2'-F-dC(dmf)-CE-Phosphoramidite is a phosphoramidite compound used in the synthesis of modified oligonucleotides. This molecule is derived from deoxycytidine (dC) and features several modifications: a dimethoxytrityl (DMT) group at the 5' position, a fluorine atom at the 2' position, and a dimethylformamidine (dmf) protecting group on the exocyclic amino group of the cytosine base. The phosphoramidite group is attached to the 3' position, enabling its incorporation into synthetic DNA sequences. DMT-2'-F-dC(dmf)-CE-Phosphoramidite is particularly valuable in creating stable and effective oligonucleotides for diagnostic tools, therapeutic agents, and in studying nucleic acid interactions. The fluorine substitution at the 2' position also contributes to improved binding affinity and specificity in hybridization assays, making this compound a versatile tool in molecular biology and medical research. Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxopyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-N4-DMF-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; 2'-F C(DMF) amidite; 2'-Fluoro-C(DMF)-3'-phosphoramidite; N4-DMF-5'-O-DMT-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; N4-Dimethy. Grade: ≥98%. Molecular formula: C42H52FN6O7P. Mole weight: 802.89. | |
| DMTr-FNA-C(Bz)phosphoramidite | DMTr-FNA-C(Bz)phosphoramidite is an essential compound assuming the role of a phosphoramidite foundational component, expediting the fabrication of nucleic acid analogs. Through its distinctive configuration, it is harnessed in the fabrication of modified oligonucleotides, specifically tailored for investigative applications, notably in the precise targeting of disease-correlated DNA or RNA sequences encompassing afflictions like cancer and viral infections. Synonyms: FNA C(Bz) amidite; N4-Benzoyl-1-[[2-O-(4,4'-dimethoxytrityloxy)-1-(hydroxymethyl)ethoxy]methyl]cytosine CED phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]methoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; 2-((4-Benzamido-2-oxopyrimidin-1(2H)-yl)methoxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. CAS No. 326802-62-4. Molecular formula: C45H52N5O8P. Mole weight: 821.90. | |
| DMTr-TNA-U amidite | DMTr-TNA-U amidite is a phosphoramidite monomer used in the RNA synthesis. Synonyms: TNA-U CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-4-[bis(4-methoxyphenyl)phenylmethoxy]-2-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)tetrahydro-3-furanyl 2-cyanoethyl ester; (2R,3R,4S)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DMTr-TNA-U-Phosphoramidite. CAS No. 325683-95-2. Molecular formula: C38H45N4O8P. Mole weight: 716.76. | |
| D-?Ribitol, 1,?4-?anhydro-?5-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2-?O-?methyl-?1-?C-?phenyl-?, 3-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite]?, (1S)?- | D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-1-C-phenyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], (1S)- is an indispensable phosphoramidite with application in oligonucleotide synthesis enabling the intricate modification and functionalization of nucleic acids. Synonyms: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-phenyltetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1418182-88-3. Molecular formula: C42H51N2O7P. Mole weight: 726.84. | |
| dSpacer-CEP | dSpacer is used to introduce stable abasic sites in oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 129821-76-7. Molecular formula: C35H45N2O6P. Mole weight: 620.71. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98. | |
| Guanosine, 3'-?deoxy-?2'-?O-?ethyl-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-N-(2-methyl-1-oxopropyl)?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a pivotal constituent, emanates as a linchpin in the explicit domain of nucleic acid synthesis, intently within DNA and RNA exploration. It confers enhanced prospects for manufacturing modified nucleotides as well as derivatives pertaining to nucleic acids, necessitated for investigations encompassing the structural, functional and behavioral attributes pertinent to DNA and RNA molecules, rendering significant insights. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-ethoxy-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 2299279-11-9. Molecular formula: C45H57N8O7P. Mole weight: 852.96. | |
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