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Phosphine Ligands. Alternative Names: Benzo[d][1,3]benzodioxepin-1-yl(dicyclohexyl)phosphane. CAS No. 1256170-06-5. Molecular formula: C25H31O2P. Mole weight: 394.49. Purity: 0.98. IUPACName: benzo[d][1,3]benzodioxepin-1-yl(dicyclohexyl)phosphane. Catalog: ACM1256170065.
n-Propyl Dioxepin
N-Propyl Dioxepin, a chemical compound, has been found to hold immense potential in the field of neuroscience due to its ability to be leveraged in the creation of new pharmaceuticals that are aimed at treating a range of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. This compound has been shown to be a wonderfully proficient antagonist of the dopamine receptors, as evidenced by preclinical studies. Synonyms: 2-Propyl-4,7-dihydro-1,3-dioxepine. CAS No. 4469-34-5. Molecular formula: C8H14O2. Mole weight: 142.198.
11-Azaartemisinin
11-Azaartemisinin. Group: Biochemicals. Alternative Names: (3R, 5aS, 6R, 8aS, 9R, 12R, 12aR)-Decahydro-3, 6, 9-trimethyl-3, 12-epoxy-1, 2-dioxepino[4, 3-i]isoquinolin-10(3H)-one; (-)-11-Azaartemisinin. Grades: Highly Purified. CAS No. 162791-23-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H23NO4. US Biological Life Sciences.
Worldwide
2-Chlorovirensic acid
2-Chlorovirensic acid is a derivative of Virensic acid, which is produced by the strain of Sulcaria sulcata (lichenized Ascomycotina). Synonyms: Chlorovirensic acid; 2-Chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid; 5-Chlorovirensic acid. CAS No. 103805-92-1. Molecular formula: C18H13ClO8. Mole weight: 392.74.
2-Methoxypsoromic acid
2-Methoxypsoromic acid is a lichen depsidone from Pertusaria and Sulcaria species. Synonyms: 4-Formyl-3-hydroxy-2,8-dimethoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid. CAS No. 253161-37-4. Molecular formula: C19H16O9. Mole weight: 388.32.
It is a novel phthalide catabolite of depsidone and new metabolite of the lichen Buellia canescens(dicks.) de not. Synonyms: 2,7,9-trichloro-3,8-dimethoxy-1,6-dimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one; Dechloro-O-methyldiploicin. Molecular formula: C17H13Cl3O5. Mole weight: 403.64.
3-Dechlorodiploicin
It is a chlorinated depsidone isolated from the lichen Diploicia canescens. Synonyms: 2,7,9-Trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-dibenzo[b,e][1,4]dioxepin-11-one; dechlorodiploicin. CAS No. 69709-90-6. Molecular formula: C16H11Cl3O5. Mole weight: 389.62.
4-O-Methyldiploicin
4-O-Methyldiploicin is a chlorine-containing derivative from lichen. Synonyms: o-Toluic acid, 3,5-dichloro-6-[(3,5-dichloro-6-hydroxy-4-methoxy-o-tolyl)oxy]-4-methoxy-, ε-lactone (7CI); 2,4,7,9-Tetrachloro-3,8-dimethoxy-1,6-dimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,4,7,9-tetrachloro-3,8-dimethoxy-1,6-dimethyl-. CAS No. 19314-80-8. Molecular formula: C17H12Cl4O5. Mole weight: 438.09.
It is the constituent of Psoroma allorhizum. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-6-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,4,9-trimethyl-11-oxo-. CAS No. 84592-16-5. Molecular formula: C18H14Cl2O6. Mole weight: 397.21.
Artemotil is a fast-acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria. Uses: Amebicides. Synonyms: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran; 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, [3R-(3α, 5aβ, 6β, 8aβ, 9α, 10α, 12β, 12aR*)]-; (+)-Arteether; Artemotil; Dihydroartemisinin ethyl ether; Dihydroqinghaosu ethyl ether; NSC 665971; SM 227; β-Arteether; β-Dihydroartemisinin ethyl ether. Grades: ≥95%. CAS No. 75887-54-6. Molecular formula: C17H28O5. Mole weight: 312.41.
Artesunate
Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1). Group: Inhibitors. Alternative Names: 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid. CAS No. 88495-63-0. Molecular formula: C19H28O8. Mole weight: 384.42. Appearance: White powder. Purity: 0.98. IUPACName: 4-Oxo-4-[[(1R, 4S, 5R, 8S, 9R, 10S, 12R, 13R)-1, 5, 9-trimethyl-11, 14, 15, 16-tetraoxatetracyclo[10.3.1.04, 13.08, 13]hexadecan-10-yl]oxy]butanoic acid. Canonical SMILES: C[C@@H]1CC[C@H]2[C@H] ([C@@H] (O[C@H]3[C@@]24[C@H]1CC[C@] (O3) (OO4)C)OC (=O)CCC (=O)O)C. Density: 1.21 g/ml. Catalog: ACM88495630.
It is the depsidone isolated from the lichen Xanthoparmelia xanthosorediata. Synonyms: 3,8-Dihydroxy-1-pentanoyl-6-propyl-dibenzo[b,e][1,4]dioxepin-11-one; Conlorlobaridon; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 3,8-dihydroxy-1-(1-oxopentyl)-6-propyl-. CAS No. 71521-80-7. Molecular formula: C21H22O6. Mole weight: 370.40.
Conprotocetraric acid
Conprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Usnea trichodeoides. Synonyms: 6,14-dihydroxy-7,15-bis(hydroxymethyl)-4,12-dimethyl-10-oxo-2,9-dioxatricyclo[9.4.0.0(3,8)]pentadeca-1(11),3(8),4,6,12,14-hexaene-5-carboxylic acid; 3,8-dihydroxy-4,9-bis(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C18H16O9. Mole weight: 376.31.
Consuccinprotocetraric acid
Consuccinprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Flavoparmelia succinprotocetrarica. Synonyms: 9-(((3-carboxypropanoyl)oxy)methyl)-3,8-dihydroxy-4-(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C22H20O12. Mole weight: 476.39.
Depsidone is a metabolite of fungi such as Aspergillus, Emericella and Preussia. Synonyms: 11H-Dibenzo[B,E][1,4]Dioxepin-11-One. CAS No. 3580-77-6. Molecular formula: C13H8O3. Mole weight: 212.20.
Diacetylcercosporin
It is a minor hydrophobic analogue of cercosporin produced by several species of the fungal genera, cercospora and septoria. It has moderate in vitro activity against leishmania and chloroquine-sensitive strains of plasmodium falciparum. It exhibits antitumor activity. Synonyms: [S-(R*,R*)]-8,9-bis[2-(acetyloxy)propyl]-5,12-dihydroxy-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-6,11-dione; 2',2''-Diacetylcercosporin. Grades: >95% by HPLC. CAS No. 62574-06-5. Molecular formula: C33H30O12. Mole weight: 618.58.
Diploicin
It is produced by the strain of Diplocia canescens (Bullia canescens). It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Diploicine; 2,4,7,9-Tetrachloro-3-hydroxy-8-methoxy-1,6-dimethyl-11H-dibenzo[b,E][1,4]dioxepin-11-one; 11H-Dibenzo[b,e][1,4]dioxepin-11-one,2,4,7,9-tetrachloro-3-hydroxy-8-methoxy-1,6-dimethyl-; 5,6'-Dimethyl-2',3-dihydroxy-4'-methoxy-2,3',4,5'-tetrachloro-6-carboxydiphenyl ether 2',6-Lactone. CAS No. 527-93-5. Molecular formula: C16H10O5Cl4. Mole weight: 424.06.
It is a dichlorodepsidone from the lichen erioderma physcioides. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-4-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-; 2,8-dichloro-9-hydroxy-3-methoxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; 4-formyl-2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyldi-benzo[b,e][1,4]dioxepin-11-one; Eriodermine. CAS No. 92070-80-9. Molecular formula: C17H12Cl2O6. Mole weight: 383.18.
Folipastatin
Folipastatin is a fungal metabolite that is produced by A. unguis. Folipastatin is also an inhibitor of phospholipase A2 (PLA2) with an IC50 of 39 μM. Synonyms: 3,8-dihydroxy-4,9-dimethyl-1,6-bis[(1Z)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one; E323392EAO. Grades: ≥95%. CAS No. 139959-71-0. Molecular formula: C23H24O5. Mole weight: 380.43.
Fulgidin
It is the isomeric lichen depsidone of isofulgidin isolated from the lichen Rinodina dissa. Synonyms: 2,4,7-trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-dibenzo[b,e][1,4]dioxepin-11-one; Isofulgidin; 11H-dibenzo[b,e][1,4]dioxepin-11-one, 2,4,7-trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-. CAS No. 71339-43-0. Molecular formula: C16H11Cl3O5. Mole weight: 389.61.
Fumarprotocetraric acid
Fumarprotocetraric acid is originally isolated from Cetraria islandica. Synonyms: Fumarylprotocetraric acid; NSC-249984; NCGC00095467-02; [(7-carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-yl)methyl] hydrogen fumarate. Grades: >95%. CAS No. 489-50-9. Molecular formula: C22H16O12. Mole weight: 472.35.
Gadobutrol Impurity 29
Gadobutrol Impurity 29 is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Synonyms: 2,2-dimethyl-4,7-dihydro-1,3-dioxepine. CAS No. 1003-83-4. Molecular formula: C7H12O2. Mole weight: 128.17.
Glomelliferonic acid
Glomelliferonic acid is a depside from the Lichen Neofuscelia subincerta. Synonyms: ACMC-20miur; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-pentyl-; 8-Hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-pentyl-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. CAS No. 113706-23-3. Molecular formula: C25H28O8. Mole weight: 456.48.
Grayanic acid
Grayanic acid is an orcinol-type depsidone isolated from Cladonia Grayi MERRILL. Synonyms: 6-Heptyl-8-hydroxy-3-methoxy-1-methyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 6-heptyl-8-hydroxy-3-methoxy-1-methyl-11-oxo-. CAS No. 17636-19-0. Molecular formula: C23H26O7. Mole weight: 414.45.
Hypoconstictic acid
It is isolated from Usnea undulata Stirton (Usneaaceae), a fruticose lichen. Synonyms: 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-3,7(1H)-dione, 1,4-dihydroxy-5-(hydroxymethyl)-10-methoxy-8,11-dimethyl-; 1, 4-Dihydroxy-5-hydroxymethyl-10-methoxy-8, 11-dimethyl-1H-benzo[e]furo[3', 4':3, 4]benzo[b][1, 4]dioxepine-3, 7-dione. CAS No. 78916-52-6. Molecular formula: C19H16O9. Mole weight: 388.32.
Hypophysciosporin
It is isolated from the lichen Erioderma phaeorhizum. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2-chloro-3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-, methyl ester; 2-chloro-3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid methyl ester. Grades: ≥95%. CAS No. 64662-23-3. Molecular formula: C19H17ClO7. Mole weight: 392.79.
Hypoprotocetraric acid
It is a depsidone from lichen species of Cladonia genus (C. fimbriata, C. furcata, C. subulata, C. foliacea and C. rangiferina). Synonyms: Coquimboic acid; 3,9-dihydroxy-1,4,7,10-tetramethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; Hypoprotocetrarsaeure; 3,8-Dihydroxy-1,4,6,9-tetramethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carbonsaeure; 1,4,6,9-Tetramethyl-3,8-dihydroxy-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid; Benzoic acid, 3-(2-carboxy-5-hydroxy-3,6-dimethylphenoxy)-4,6-dihydroxy-2,5-dimethyl-, ε-lactone. CAS No. 4665-2-5. Molecular formula: C18H16O7. Mole weight: 344.32.
Hypostictic acid
It has moderate inhibitory activity against the growth of Mycobacterium tuberculosis. Synonyms: Hypostatic acid; 1, 4-Dihydroxy-10-methoxy-5, 8, 11-trimethyl-1H-benzo[e]furo[3', 4':3, 4]benzo[b][1, 4]dioxepine-3, 7-dione; 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-3,7(1H)-dione, 1,4-dihydroxy-10-methoxy-5,8,11-trimethyl-. Grades: ≥98%. CAS No. 68729-11-3. Molecular formula: C19H16O8. Mole weight: 372.33.
Isonotatic acid
It has been detected in strains of the lichen Parmelia notata Kurok. Synonyms: 11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid, 8-hydroxy-3-methoxy-1,6,9-trimethyl-11-oxo-. CAS No. 90689-48-8. Molecular formula: C18H16O7. Mole weight: 344.32.
Isovicanicin
It has been isolated from Psoroma lichens. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-8-hydroxy-3-methoxy-1,4,6,9-tetramethyl-. CAS No. 84592-15-4. Molecular formula: C18H16Cl2O5. Mole weight: 383.22.
Lecideoidin
It is the depsidone isolated from a Lecidea sp. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,9-dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-, methyl ester; 2,9-Dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid methyl ester. CAS No. 72458-10-7. Molecular formula: C17H12Cl2O7. Mole weight: 399.18.
Loxodellonic acid is a depside from the Lichen Neofuscelia subincerta. Synonyms: ACMC-20mit2; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 8-hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-propyl-. CAS No. 113689-49-9. Molecular formula: C23H24O8. Mole weight: 428.43.
Loxodin
Loxodin is a depsidone isolated from Parmelia flavescentireagens Gyel. Synonyms: Neoloxodic acid; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-11-oxo-6-pentyl-1-valeryl-, methyl ester (8CI). CAS No. 29813-50-1. Molecular formula: C25H28O8. Mole weight: 456.48.
Methyl 2,7-dichloropsoromate, the depsidone, has been isolated from the lichen Phyllopsora corallina var. ochroxantha. Synonyms: 2,7-Dichloro-4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid methyl ester. CAS No. 131840-47-6. Molecular formula: C19H14Cl2O8. Mole weight: 441.22.
Methyl 2-chloropsoromate
Methyl 2-chloropsoromate, the depsidone, has been isolated from the lichen Phyllopsora corallina var. ochroxantha. Synonyms: 2-chloro-4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid methyl ester. Molecular formula: C19H15ClO8. Mole weight: 406.77.
It is isolated from an unidentified Lecanora sp. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-11-oxo-1,6-dipentyl-; 3,9-dihydroxy-6-oxo-1,7-dipentylbenzo[b][1,4]benzodioxepine-2-carboxylic acid. CAS No. 79579-61-6. Molecular formula: C24H28O7. Mole weight: 428.47.
Norgangaleoidin
It is a new dichlorodepsidone isolated from Lecanora chlarotera. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,4-dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-, methyl ester; 3'-Dechlorolecideiodin. CAS No. 71478-26-7. Molecular formula: C17H12Cl2O7. Mole weight: 399.18.
A depsidone produced by several fungal species; has potent and selective antibacterial activity; has potential as an anti-inflammatory agent. Synonyms: Ustin; 2,4,7-Trichloro-3,8-dihydroxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo(b,E)(1,4)dioxepin-11-one. Grades: >99% by HPLC. CAS No. 33403-37-1. Molecular formula: C19H15Cl3O5. Mole weight: 429.68.
It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2,5-Ethanoanthra[2,3-d]-1,3-dioxepin-7,12-dione, 4,5-dihydro-6,8,10-trihydroxy-2-methyl-, (1R,17R)-. CAS No. 162797-36-6. Molecular formula: C20H16O7. Mole weight: 368.34.
Pannarin
It is a lichen metabolite isolated from several Psoroma species. Synonyms: 8-chloro-9-hydroxy-3-methoxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; Pannarine; NSC 646008; 11H-Dibenzo(b,e)(1,4)dioxepin-4-carboxaldehyde, 2-chloro-3-hydroxy-8-methoxy-1,6,9-trimethyl-11-oxo-. CAS No. 55609-84-2. Molecular formula: C18H15ClO6. Mole weight: 362.76.
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