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A thiol-activated peptidase from cabbage (Brassica oleracea). Tetrapeptides are formed from Ala-Ala, Gly-Gly, Ala-Gly and Gly-Ala. Group: Enzymes. Synonyms: dipeptidyl tetrapeptide hydrolase; dipeptidyl ligase; tetrapeptide dipeptidase. Enzyme Commission Number: EC 3.4.14.6. CAS No. 91608-92-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4051; dipeptidyl-dipeptidase; EC 3.4.14.6; 91608-92-3; dipeptidyl tetrapeptide hydrolase; dipeptidyl ligase; tetrapeptide dipeptidase. Cat No: EXWM-4051.
Dipeptidyl Peptidase 3 (DPP3), GST-Tag, Recombinant, Human (Lyophilized)
Human DPP3 (GenBank Accession No. NM_130443), (full length) with N-terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. Group: Molecular Biology. Grades: Purified. Pack Sizes: custom. US Biological Life Sciences.
Worldwide
dipeptidyl-peptidase I
A Cl--dependent, lysosomal cysteine-type peptidase maximally active at acidic pH. Also polymerizes dipeptide amides, arylamides and esters at neutral pH. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: cathepsin C; dipeptidyl aminopeptidase I; dipeptidyl transferase; cathepsin C; dipeptidyl transferase; dipeptide arylamidase I; DAP I. Enzyme Commission Number: EC 3.4.14.1. CAS No. 9032-68-2. CTSC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4043; dipeptidyl-peptidase I; EC 3.4.14.1; 9032-68-2; cathepsin C; dipeptidyl aminopeptidase I; dipeptidyl transferase; cathepsin C; dipeptidyl transferase; dipeptide arylamidase I; DAP I. Cat No: EXWM-4043.
dipeptidyl-peptidase II
A lysosomal serine-type peptidase in family S28 (Pro-X carboxypeptidase family); maximally active at acidic pH. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase II; dipeptidyl arylamidase II; carboxytripeptidase; dipeptidyl peptidase II; dipeptidyl arylamidase II; DAP II; dipeptidyl(amino)peptidase II; dipeptidylarylamidase. Enzyme Commission Number: EC 3.4.14.2. CAS No. 76199-23-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4048; dipeptidyl-peptidase II; EC 3.4.14.2; 76199-23-0; dipeptidyl aminopeptidase II; dipeptidyl arylamidase II; carboxytripeptidase; dipeptidyl peptidase II; dipeptidyl arylamidase II; DAP II; dipeptidyl(amino)peptidase II; dipeptidylarylamidase. Cat No: EXWM-4048.
dipeptidyl-peptidase III
A cytosolic peptidase that is active at neutral pH. It has broad activity on peptides, although it is highly selective for Arg-Arg-2-naphthylamide, at pH 9.2. Active in the hydrolysis of enkephalins. A metallopeptidase, the type example of peptidase family M49. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Enzyme Commission Number: EC 3.4.14.4. CAS No. 77464-87-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4049; dipeptidyl-peptidase III; EC 3.4.14.4; 77464-87-0; dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Cat No: EXWM-4049.
dipeptidyl-peptidase IV
A homodimer. An integral protein of the plasma membrane of lymphocytes and other mammalian cells, in peptidase family S9 (prolyl oligopeptidase family). The reaction is similar to that of the unrelated EC 3.4.14.11 Xaa-Pro dipeptidyl-peptidase of lactococci. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptida. Enzyme Commission Number: EC 3.4.14.5. CAS No. 54249-88-6. DPP IV. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4050; dipeptidyl-peptidase IV; EC 3.4.14.5; 54249-88-6; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidyl-aminopeptidase IV; DPP IV/CD26; amino acyl-prolyl dipeptidyl aminopeptidase; T cell triggering molecule Tp103; X-PDAP. Cat No: EXWM-4050.
Dipeptidyl peptidase IV
Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPP-IV. CAS No. 54249-88-6. Pack Sizes: 10 mU. Product ID: HY-E70397.
Dipeptidyl Peptidase IV from Human, Recombinant
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide, which functions as the membrane anchoring domain. There is an 88% sequence homology between the human and porcine kidney enzymes. Both exist as homodimers with a subunit molecular weight of ~30 kDa. The high mannose 100 kDa DPPIV precursor is processed in the Golgi to yield a 124 kDa heavily N-and O-linked mature glycoprotein. It is then sorted to the apical membrane through the concerted action of both N-and O-linked glycans and its association with lipid microdomains. The porcine enzyme contai...zyme from creative enzymes has been used to study the lc-ms (liquid chromatography-mass spectrometry) based assay method for dpp-iv inhibitor screening and substrate discovery. Group: Enzymes. Synonyms: EC 3.4.14.5; 54249-88-6; DPPIV; DPP4; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidy
DPP7 is essential for maintaining lymphocytes and fibroblasts in G (0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53. DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. Contains amino acids 29 to end with a c-terminal his tag, mw=89.1 kda. Applications: Dipeptidyl peptidase vii (dpp7), also known as dpp2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymph ocytes. dpp7 is used to study the regulation of cell quiescence. like dpp4, dpp7 may be useful in diabetes and vascular disease research. Group: Enzymes. Synonyms: EC 3.4.14.-; DPP7; Quiescent cell proline dipeptidase; Dipeptidyl Peptidase VII; DPP VII. Enzyme Commission Number: EC 3.4.14.-. DPP VII. Mole weight: 89.1 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 130 mM NaCl, 0.05% Tween-20, 10% glycerol. Source: Sf9 cells. Species: Human. EC 3.4.14.-; DPP7; Quiescent cell proline dipeptidase; Dipeptidyl Peptidase VII; DPP VII. Cat No: NATE-0206.
γ-D-glutamyl-L-lysine dipeptidyl-peptidase
The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the recycling of the murein peptide. Group: Enzymes. Synonyms: YkfC. Enzyme Commission Number: EC 3.4.14.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4047; γ-D-glutamyl-L-lysine dipeptidyl-peptidase; EC 3.4.14.13; YkfC. Cat No: EXWM-4047.
Native Human Dipeptidyl Peptidase-4
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide, which functions as the membrane anchoring domain. There is an 88% sequence homology between the human and porcine kidney enzymes. Both exist as homodimers with a subunit molecular weight of ~30 kDa. The high mannose 100 kDa DPPIV precursor is processed in the Golgi to yield a 124 kDa heavily N-and O-linked mature glycoprotein. It is then sorted to the apical membrane through the concerted action of both N-and O-linked glycans and its association with lipid microdomains. The porcine enzyme contains 18....Store at -20°C. Form: Liquid. Source: Human Placenta. Species: Human. EC 3.4.14.5; 54249-88-6; DPPIV; DPP4; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidyl-aminopeptidase IV; DPP IV/CD26; amino acyl-prolyl dipeptidyl aminopeptidase; T cell triggering molecule Tp103; X-PDAP. Cat No: NATE-0962.
Native Porcine Dipeptidyl Peptidase IV
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide, which functions as the membrane anchoring domain. There is an 88% sequence homology between the human and porcine kidney enzymes. Both exist as homodimers with a subunit molecular weight of ~30 kDa. The high mannose 100 kDa DPPIV precursor is processed in the Golgi to yield a 124 kDa heavily N-and O-linked mature glycoprotein. It is then sorted to the apical membrane through the concerted action of both N-and O-linked glycans and its association with lipid microdomains. The porcine enzyme contains 18...ukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidyl-aminopeptidase IV; DPP IV/CD26; amino acyl-prolyl dipeptidyl aminopeptidase; T cell triggering molecule Tp103; X-PDAP. Enzyme Commission Number: EC 3.4.14.5. CAS No. 54249-88-6. Purity: >94% by SDS-PAGE. DPP IV. Activity: 1.0 U/mg; Specific Activity >40 U/mg protein. Storage: at -70°C, Avoid freeze/thaw. Form: Liquid. In 20 mM Tris-HCl, 5 mM CaCl?, 1 uM ZnCl?, 0.05% NaN?, pH 8.0. Source: Porcine Kidney. Species: Porcine. EC 3.4.14.5; 54249-88-6; DPPIV; DPP4; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidas
Xaa-Pro dipeptidyl-peptidase
The intracellular enzyme from Lactococcus lactis (190-kDa) is the type example of peptidase family S15. The reaction is similar to that catalysed by dipeptidyl-peptidase IV of animals. Group: Enzymes. Synonyms: X-prolyl dipeptidyl aminopeptidase; PepX; X-prolyl dipeptidyl peptidase; X-Pro dipeptidyl-peptidase. Enzyme Commission Number: EC 3.4.14.11. CAS No. 54249-88-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4045; Xaa-Pro dipeptidyl-peptidase; EC 3.4.14.11; 54249-88-6; X-prolyl dipeptidyl aminopeptidase; PepX; X-prolyl dipeptidyl peptidase; X-Pro dipeptidyl-peptidase. Cat No: EXWM-4045.
An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: Carbamic acid, N-[(3R)-1-[(2-cyanophenyl)methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester. CAS No. 1353254-15-5. Molecular formula: C18H25N3O2. Mole weight: 315.41.
1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine
1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 401566-79-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C14H18N4. US Biological Life Sciences.
Worldwide
14-3-3 Antagonist I, 2-5 ( (S) -2- (2- (4-Azidobenzamido) acetamido) -3- ( (4-hydroxyphenethyl) amino) -3-oxopropyl-dihydrogen Phosphate)
A cell-permeable dipeptidyl-phosphoserine compound that effectively disrupts 14-3-3 interaction with its ligands (IC50=2.6uM against TMR-GG-RLSHpSSLPG binding to human 14-3-3 sigma), including Raf-1 and p53. Shown to induce caspase-3 activation and apoptotic cell death in human lung adenocarcinoma A549 cultures (100uM) in a time-dependent manner. Group: Biochemicals. Grades: Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?P, Molecular Weight: 506.4. US Biological Life Sciences.
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1253056-01-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H14F6N4O2. US Biological Life Sciences.
Worldwide
1-Amino-3-nitroadamantane
1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 243145-00-8. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H16N2O2, Molecular Weight: 196.25. US Biological Life Sciences.
(1aS, 4S, 6aR, 7aS)-6-Amino-4-(3, 5-dihydroxytricyclo[3. 3. 1. 13, 7]dec-1-yl)-1, 1a, 4, 6a, 7, 7a-hexahydro-3H-cyclopropa[4, 5]pyrrolo[1, 2-a]pyrazin-3-one is a metabolite of Saxagliptin (S143500); a potent dipeptidyl peptidase-4 inhibitor approved for the treatment of type 2 diabetes mellitus. Group: Biochemicals. Grades: Highly Purified. CAS No. 1429782-93-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H25N3O3, Molecular Weight: 331.41. US Biological Life Sciences.
Worldwide
1-Bromo-3-methyl-2-butene (90%)
1-Bromo-3-methyl-2-butene is used to prepare xanthine dipeptidyl peptidase inhibitors for treatment of type 2 diabetes. It can also be used to synthesize natural and non-natural prenylated chalcones with antitumor, antioxidant activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 870-63-3. Pack Sizes: 1g, 5g. Molecular Formula: C5H9Br, Molecular Weight: 149.03. US Biological Life Sciences.
Worldwide
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 2,2,2-Trifluoroacetic Acid 2-(2-Chloroacetyl)hydrazide; N'-(chloroacetyl)-2,2,2-trifluoroacetohydrazide. Grades: >95%. CAS No. 762240-99-3. Molecular formula: C4H4ClF3N2O2. Mole weight: 204.53.
1- (Ethylamino) cyclopentanemethanol
1- (Ethylamino) cyclopentanemethanol is a potent and selective inhibitor of dipeptidyl peptidase IV, a critical enzyme of potential value in the treatment of type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 852108-25-9. Pack Sizes: 250mg, 1g. Molecular Formula: C8H17NO, Molecular Weight: 143.229999999999. US Biological Life Sciences.
Worldwide
1-Methylcyclopentanol
1-Methylcyclopentanol is used as a reagent in the synthesis of cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV. It is also used in the preparation of Lomifylline (L470200) which is a methylxanthine analog that induces Ca2+-release from intracellular stores via the ryanodine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1462-03-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H12O. US Biological Life Sciences.
It is a substrate for the fluorescent assay of angiotensin I-converting enzyme and of the bacterial dipeptidyl carboxypeptidase from Escherichia coli. Synonyms: 2-Aminobenzoylglycyl-4-nitrophenylalanyl-proline; Abz-Gly-p-nitro-Phe-Pro-OH; L-Proline,N-(2-aminobenzoyl)glycyl-4-nitro-L-phenylalanyl-; o-Aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline. CAS No. 67482-93-3. Molecular formula: C23H25N5O7. Mole weight: 483.47.
(1S, 3S, 5S)-2-Azabicyclo[3. 1. 0]hexane-3-carboxamide is an intermediate used to prepare dipeptidyl peptidase IV (DDP-IV) inhibitors as potential antidiabetes agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 361440-68-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H10N2O, Molecular Weight: 126.16. US Biological Life Sciences.
(1S, 3S, 5S)-2-Azabicyclo[3. 1. 0]hexane-3-carboxamide is an intermediate used to prepare dipeptidyl peptidase IV (DDP-IV) inhibitors as potential antidiabetes agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 709031-39-0. Pack Sizes: 100mg, 500mg. Molecular Formula: C6H11ClN2O. US Biological Life Sciences.
(1S, 3S, 5S)-2-Boc-2-azabicyclo[3. 1. 0]hexane-3-carboxylic Acid is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. Group: Biochemicals. Grades: Highly Purified. CAS No. 197142-36-2. Pack Sizes: 10mg, 100mg. Molecular Formula: C11H17NO4, Molecular Weight: 227.26. US Biological Life Sciences.
Boc-1-aminocyclobutane-1-carboxylic Acid is used in the synthesis of dipeptidyl nitriles with cathepsin-inhibiting activities. It is also used to prepare alkyl-oxo-aryl amides as novel antagonists of TRPA1 receptor. Synonyms: Boc-Acb(1)-OH; N-Boc-1-Aminocyclobutanecarboxylic acid; 1-(Boc-amino)cyclobutanecarboxylic Acid; 1- ( (tert-Butoxycarbonyl) amino) cyclobutanecarboxylic acid; 1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclobutane-1-carboxylic acid; N-α-(t-Butoxycarbonyl)cyclovaline. Grades: ≥ 95% (Assay). CAS No. 120728-10-1. Molecular formula: C10H17NO4. Mole weight: 215.25.
2- (2, 4, 5-Trifluorophenyl) acetaldehyde
2- (2, 4, 5-Trifluorophenyl) acetaldehyde is derived from 2,4,5-Trifluorobenzeneacetic Acid (T792625), which is used in the synthesis of EGFR/ErbB-2-kinase inhibitors. Also used in the synthesis of new imidazopyrazinone derivatives as potnetial dipeptidyl peptidase IV inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 111991-20-9. Pack Sizes: 250mg, 1g. Molecular Formula: C8H5F3O, Molecular Weight: 174.12. US Biological Life Sciences.
An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: Benzonitrile, 2-[[3,4-dihydro-3-methyl-2,4-dioxo-6-[(3R)-3-piperidinylamino]-1(2H)-pyrimidinyl]methyl]-. CAS No. 2089611-85-6. Molecular formula: C18H21N5O2. Mole weight: 339.39.
2, ?4, ?5-?Trifluoro Benzene acetic Acid
2,4,5-Trifluorobenzeneacetic Acid is used in the synthesis of EGFR/ErbB-2-kinase inhibitors. Also used in the synthesis of new imidazopyrazinone derivatives as potnetial dipeptidyl peptidase IV inhibitors. Group: Biochemicals. Alternative Names: (2,4,5-Trifluorophenyl)acetic Acid. Grades: Highly Purified. CAS No. 209995-38-0. Pack Sizes: 2.5g. US Biological Life Sciences.
2,?4,?5-?Trifluoro-benzeneacetic acid methyl ester is used for the synthesis of Dipeptidyl Peptidase-?4 (DPP-?4) Inhibitor, (R)?-?Sitagliptin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036273-20-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C9H7F3O2, Molecular Weight: 204.15. US Biological Life Sciences.
Worldwide
2,4-Dichloro-5-ethylpyrimidine
2,4-Dichloro-5-ethylpyrimidine is a reactant used for the synthesis of pyrimidine derivatives as inhibitors of dipeptidyl peptidase IV, TBK1/IKKε kinases, and as an inhibitor of a hedgehog signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 34171-40-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C6H6Cl2N2, Molecular Weight: 177.03. US Biological Life Sciences.
Worldwide
2,4-Dichloro-5-nitrophenol
2,4-Dichloro-5-nitrophenol is an intermediate used to prepare (5-Substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as Potent Dipeptidyl Peptidase IV Inhibitors. It is also used to synthesize cyanopyrrolo[2,3-d]pyrimidine derivatives as Hsp90 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 39489-77-5. Pack Sizes: 1g, 5 g. Molecular Formula: C6H3Cl2NO3. US Biological Life Sciences.
Worldwide
2,5-Dichlorophenylboronic Acid
2,5-Dichlorophenylboronic Acid is a reactant in the synthesis of of Dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 135145-90-3. Pack Sizes: 1g, 5g. Molecular Formula: C6H5BCl2O2. US Biological Life Sciences.
Worldwide
2',5'-Difluoroacetophenone
2',5'-Difluoroacetophenone is used in the synthesis of pyrazole compounds as inhibitors of dipeptidyl peptidases. These compounds have been shown to produce anti-hyperglycemic effects. Group: Biochemicals. Alternative Names: 1- (2, 5-Difluorophenyl) ethanone; 1- (2, 5-Difluorophenyl) ethanone; 2,5-Difluorophenyl Methyl Ketone. Grades: Highly Purified. CAS No. 1979-36-8. Pack Sizes: 10g. US Biological Life Sciences.
2-[(6-Chloro-3-ethyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile is an impurity of alogliptin (A575425), which is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Group: Biochemicals. Grades: Highly Purified. CAS No. 1430222-06-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H12ClN3O2, Molecular Weight: 289.72. US Biological Life Sciences.
Worldwide
2-(aminomethyl)benzonitrile hydrochloride
2-(aminomethyl)benzonitrile hydrochloride is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: 2-(aminomethyl)benzonitrile; hydrochloride; 2-(aminomethyl)benzonitrile; hydrochloride. CAS No. 1134529-25-1. Molecular formula: C8H9ClN2. Mole weight: 168.62.
2- (Bromomethyl) benzonitrile
2- (Bromomethyl) benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 22115-41-9. Pack Sizes: 1g, 5g. Molecular Formula: C8H6BrN. US Biological Life Sciences.
2-?Chloro-?6,?7-?dimethoxy-?3H-?quinazolin-?4-?one has been used as a reactant for the synthesis of Alogliptin, a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV. Group: Biochemicals. Grades: Highly Purified. CAS No. 20197-86-8. Pack Sizes: 1g, 10g. Molecular Formula: C10H9ClN2O3, Molecular Weight: 240.64. US Biological Life Sciences.
2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 2-Chloromethyl-5-trifluoromethyl-1,3,4-oxadiazole. Grades: 98.0 %. CAS No. 723286-98-4. Molecular formula: C4H2ClF3N2O. Mole weight: 186.52.
2-Dibromomethyl-benzonitrile
2-Dibromomethyl-benzonitrile is an impurity of Alogliptin (A575425), which is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Group: Biochemicals. Grades: Highly Purified. CAS No. 655-63-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H5Br2N. US Biological Life Sciences.
Worldwide
2-Hydrazinopyrazine
2-Hydrazinopyrazine is used as a reagent in the synthesis of Sitagliptin (S491000, H3PO4) and its analogs. Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor that has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 54608-52-5. Pack Sizes: 250mg, 1g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences.
Worldwide
2-Oxobutanal
2-Oxobutanal was used as a reagent in the preparation of dipeptidyl enoates which may act as potent rhodesain inhibitors. It was under investigation as a mutagen that reacts with 2'-deoxyguanosine in model systems of lipid peroxidation to form an adduct. Group: Biochemicals. Grades: Highly Purified. CAS No. 4417-81-6. Pack Sizes: 250mg, 500mg. Molecular Formula: C4H6O2, Molecular Weight: 86.09. US Biological Life Sciences.
Worldwide
(2R,2S,cis)-Deoxy-saxagliptin
(2R,2S,cis)-Deoxy-saxagliptin is an impurity of Saxagliptin (S143500) which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C18H25N3O, Molecular Weight: 299.41. US Biological Life Sciences.
Worldwide
(2'R,2S,cis)-Saxagliptin
An impurity of Saxagliptin. Saxagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) used as a hypoglycemic drug. It was approved to treat type 2 diabetes. Synonyms: (1S,3S,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Grades: 95%. CAS No. 1564265-93-5. Molecular formula: C18H25N3O2. Mole weight: 315.417.
(2R,2S,trans)-Deoxy-saxagliptin
(2R,2S,trans)-Deoxy-saxagliptin is an impurity of Saxagliptin (S143500) which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C18H25N3O, Molecular Weight: 299.41. US Biological Life Sciences.
Worldwide
(2R,3R,5R)-Omarigliptin
(2R,3R,5R)-Omarigliptin is an isomer of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H20F2N4O3S, Molecular Weight: 398.43. US Biological Life Sciences.
Worldwide
(2R,3R,5R)-Omarigliptin-d3
(2R,3R,5R)-Omarigliptin-d3 is a labelled impurity of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H17D3F2N4O3S, Molecular Weight: 401.45. US Biological Life Sciences.
Worldwide
(2R,3R,5S)-Omarigliptin
(2R,3R,5S)-Omarigliptin is an isomer of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H20F2N4O3S, Molecular Weight: 398.43. US Biological Life Sciences.
Worldwide
(2R,3R,5S)-Omarigliptin-d3
(2R,3R,5S)-Omarigliptin-d3 is a labelled impurity of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H17D3F2N4O3S, Molecular Weight: 401.45. US Biological Life Sciences.
Worldwide
(2R,3S,5S)-Omarigliptin
(2R,3S,5S)-Omarigliptin is an isomer of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C17H20F2N4O3S, Molecular Weight: 398.43. US Biological Life Sciences.
Worldwide
(2R,3S,5S)-Omarigliptin-d3
(2R,3S,5S)-Omarigliptin-d3 is a labelled impurity of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H17D3F2N4O3S, Molecular Weight: 401.45. US Biological Life Sciences.
2-[[(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]amino]succinic Acid is a derivative of the parent compound Sitagliptin Phosphate (S491000), which is a trizolopyrazine dipeptidyl peptidase IV inhibitor and it has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C24H17F6N5O3, Molecular Weight: 537.41. US Biological Life Sciences.
Worldwide
(2R,4R)-Teneligliptin
(2R,4R)-Teneligliptin is a stereoisomer of Teneligliptin (T018300, HBr); a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body. Group: Biochemicals. Grades: Highly Purified. CAS No. 1404559-17-6. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C22H30N6OS, Molecular Weight: 426.58. US Biological Life Sciences.
Worldwide
(2R,4R)-Teneligliptin-d8
(2R,4R)-Teneligliptin-d8 is the isotope labelled analog of (2R,4R)-Teneligliptin (T018320); a stereoisomer of Teneligliptin (T018300, HBr) which is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C22H22D8N6OS, Molecular Weight: 434.63. US Biological Life Sciences.
Worldwide
(2R,4S)-Teneligliptin
(2R,4S)-Teneligliptin is a stereoisomer of Teneligliptin (T018300, HBr); a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C22H30N6OS, Molecular Weight: 426.58. US Biological Life Sciences.
Worldwide
(2R,4S)-Teneligliptin-d8
(2R,4S)-Teneligliptin-d8 is the isotope labelled analog of (2R,4S)-Teneligliptin (T018315); a stereoisomer of Teneligliptin (T018300, HBr) which is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C22H22D8N6OS, Molecular Weight: 434.63. US Biological Life Sciences.
Worldwide
(2R)-Vildagliptin
(2R)-Vildagliptin is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4) which can act as a serine exopeptidase. Aside from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036959-27-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H25N3O2. US Biological Life Sciences.
Worldwide
(2R)-Vildagliptin
(2R)-Vildagliptin is an R-enantiomer of Vildagliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor used as an anti-hyperglycemic agent and an anti-diabetic drug. Synonyms: Vildagliptin Related Compound A; (2R)-1-[2-[[(5S,7R)-3-hydroxy-1-adamantyl]amino]acetyl]pyrrolidine-2-carbonitrile. Grades: ≥ 98%. CAS No. 1036959-27-9. Molecular formula: C17H25N3O2. Mole weight: 303.406.
(2S,2R,cis)-Saxagliptin
(2S,2R,cis)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1564265-94-6. Pack Sizes: 500ug, 5mg. Molecular Formula: C18H25N3O2, Molecular Weight: 315.41. US Biological Life Sciences.
Worldwide
(2S,2R,trans)-Saxagliptin
(2S,2R,trans)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1564266-00-7. Pack Sizes: 500ug, 5mg. Molecular Formula: C18H25N3O2, Molecular Weight: 315.41. US Biological Life Sciences.
(2S, 2'S) -1, 1'- [ [ (3- hydroxytri cyclo [3. 3. 1. 13, 7] dec-1-yl) imino] bis (1-oxo-2, 1-ethane diyl) ] bis-2-pyrrolidinecarbonitri le is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4). Group: Biochemicals. Grades: Highly Purified. CAS No. 1036959-23-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H33N5O3. US Biological Life Sciences.
Worldwide
(2S,3R,5R)-Omarigliptin
(2S,3R,5R)-Omarigliptin is an isomer of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H20F2N4O3S, Molecular Weight: 398.43. US Biological Life Sciences.
Worldwide
(2S,3R,5R)-Omarigliptin-d3
(2S,3R,5R)-Omarigliptin-d3 is a labelled impurity of Omarigliptin (O633100), a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C17H17D3F2N4O3S, Molecular Weight: 401.45. US Biological Life Sciences.
Worldwide
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