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Dizocilpine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. Synonyms: MK-801; MK 801; MK801; (5S)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene. Grades: ≥98%. CAS No. 77086-21-6. Molecular formula: C16H15N. Mole weight: 221.303.
Dizocilpine
Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a K d of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca 2+ flux [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-801. CAS No. 77086-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15084B.
Dizocilpine
Dizocilpine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dizocilpine;(5S)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5α,10α-imine;[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine;[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5α,10α-imine;C13737;MK-801 (Dizocilpine);5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-. CAS No. 77086-21-6. Molecular formula: C16H15N. Mole weight: 0. Purity: 99+%. IUPACName: 5H-Dibenzo[a,?d]?cyclohepten-5,?10-imine, 10,?11-dihydro-. Product ID: ACM77086216. Alfa Chemistry ISO 9001:2015 Certified.
Dizocilpine maleate
Dizocilpine maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with K d of 37.2 nM in rat brain membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-MK 801 Maleate. CAS No. 77086-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15084.
(-)-Dizocilpine maleate
(-)-Dizocilpine maleate ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-Dizocilpine maleate is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a K i of 211.7 nM. (-)-Dizocilpine maleate has antidepressant effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-MK-801 maleate. CAS No. 121917-57-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15084A.
AS 19
Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced. Group: Biochemicals. Alternative Names: (2S) - (+) -5- (1, 3, 5-Trimethylpyrazol-4-yl) -2- (dimethylamino) tetralin. Grades: Highly Purified. CAS No. 1000578-26-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 283.41. US Biological Life Sciences.
(-)-MK-801 maleate is a potent, selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM that acts at the NMDA receptor-operated ion channel as an open channel blocker. It blocks NMDA receptors in a use- and voltage-dependent manner, since the channel must open for the drug to bind inside it. It anti-convulsant and likely has dissociative anesthetic properties, but it is not used clinically for this purpose due to the discovery of brain lesions, called Olney's lesions in test rats. It were used to treat hyperalgesia in the diabetic neuropathic pain (DNP). It is used in various ischemia treatments. It has been shown to be protective in various models of ischemia as well as to inhibit behavioral sensitization to certain psychostimulants. Uses: (-)-mk-801 maleate blocks nmda receptors in a use- and voltage-dependent manner, since the channel must open for the drug to bind inside it. it were used to treat hyperalgesia in the diabetic neuropathic pain (dnp). it is used in various ischemia treatments. it has been shown to be protective in various models of ischemia as well as to inhibit behavioral sensitization to certain psychostimulants. Synonyms: (-)-MK-801 maleate; (-)-MK 801 maleate; (-)-MK801 maleate; (+)-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-diyldiammonium maleate;Dizocilpine maleate;(5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate;Dizocilpine maleate;Dizocilpine hydrogen maleate;(+)-MK-801 hydrogen maleate. Grades: >99 %. CAS No. 77086-22-7. Molecular formula: C20H19NO4. Mole weight: 337.37.
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