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| Product | Description | |
|---|---|---|
| DL-threo-PDMP hydrochloride | DL-threo-PDMP hydrochloride is the hydrochloride form of DL-threo-PDMP that is a competitive glucosylceramide synthase ( GCS ) inhibitor. DL-threo-PDMP resensitizes refractory testicular germ cell tumors and epithelial ovarian cancer orthoxenografts to cisplatin in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80938-69-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116392B. |  |
| DL-threo-PDMP hydrochloride | DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP: D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 μM. It reduces the synthesis of glucosylceramide, increases cellular ceramide, and induces cell cycle arrest in vitro. Synonyms: DL-PDMP; D,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; SMR000326846. Grades: ≥98%. CAS No. 80938-69-8. Molecular formula: C23H38N2O3·HCl. Mole weight: 427. |  |
| (+)-D-threo-PDMP hydrochloride | (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. (+)-D-threo-PDMP is an inhibitor of glucosylceramide synthase. Synonyms: d-threo-PDMP; 109836-82-0; 80938-69-8; (+)-D-threo-PDMP (hydrochloride); DL-threo-PDMP (hydrochloride); 139889-62-6; N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]decanamide; hydrochloride; N-[(1R,2R)-2-Hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride; SMR000326846; DL-threo-PDMP; (+/-)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride; D-Threo-pdmp-HCl; MLS000859987; MLS002153295; BML3-D11; CHEMBL1255585; EX-A8002H; DTXSID401017468; D-THREO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL; AKOS040755898; J-002336; D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol*HCl; N-((1R,2R)-1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide hydrochloride; Decanamide,N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-,hydrochloride(1:1),rel-. Grades: ≥98%. CAS No. 139889-62-6. Molecular formula: C23H38N2O3·HCl. Mole weight: 427.03. | |
| PDMP hydrochloride | PDMP is an inhibitor of glucosyl ceramide synthase that inhibits the synthesis and shedding of gangliosides. It reduces lysosomal activity, enhances lysosomal permeability and cytotoxicity in cells. PDMP has been used as a tool for studying various effects of endogenous glycosphingolipids. Synonyms: DL-threo-PDMP hydrochloride; DL-erythro/threo-PDMP hydrochloride; 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; (+/-)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride. Grades: ≥98%. CAS No. 73257-80-4. Molecular formula: C23H38N2O3·HCl. Mole weight: 427. | |
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