Dna Ligase Suppliers USA
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Product | Description | |
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DNA Ligase, T4, Recombinant, BioAssay Kit, T4 DNA Ligase Quick inquiry Where to buy Suppliers range | DNA Ligase, T4, Recombinant, BioAssay Kit, T4 DNA Ligase. Group: Molecular Biology. Grades: Purified. Pack Sizes: 20KU. US Biological Life Sciences. | Worldwide |
DNA ligase 3 isoform alpha precursor (790-806) Quick inquiry Where to buy Suppliers range | DNA ligase 3. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-172. | |
DNA Ligase T4 Reaction Buffer, 10X Quick inquiry Where to buy Suppliers range | DNA Ligase T4 Reaction Buffer, 10X. Group: Molecular Biology. Grades: Molecular Biology Grade. CAS No. 9015-85-4. Pack Sizes: 1.5ml. US Biological Life Sciences. | Worldwide |
DNA Ligase, T4, Recombinant, BioAssay Kit, 10mM ATP Quick inquiry Where to buy Suppliers range | DNA Ligase, T4, Recombinant, BioAssay Kit, 10mM ATP. Group: Molecular Biology. Grades: Purified. Pack Sizes: 100ul. US Biological Life Sciences. | Worldwide |
DNA Ligase, T4, Recombinant, BioAssay Kit, Reaction Buffer (10X) Quick inquiry Where to buy Suppliers range | DNA Ligase, T4, Recombinant, BioAssay Kit, Reaction Buffer (10X). Group: Molecular Biology. Grades: Purified. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
7-Propargylamino-7-deaza-dATP - 6-FAM Quick inquiry Where to buy Suppliers range | 7-Propargylamino-7-deaza-dATP - 6-FAM is a vital tool in the biomedical industry for studying DNA replication and repair mechanisms. It is commonly used as a substrate in enzymatic assays to investigate the activity of DNA polymerases and ligases. Furthermore, this compound plays a crucial role in labeling and detection of DNA during fluorescence-based techniques, assisting in the research of various genetic disorders. Synonyms: 7-Deaza-7-propargylamino-2'-deoxyadenosine-5'-triphosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C35H30N5O18P3 (free acid). Mole weight: 901.56 (free acid). | |
Ara-CTP Quick inquiry Where to buy Suppliers range | ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia. Uses: Nucleic acid synthesis inhibitors. Synonyms: 1-β-D-arabinofuranosylcytosine TP; Aracytidine-5'-Triphosphate; ara-Cytidine-5'-triphosphate; Arabinofuranosylcytosine triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 13191-15-6. Molecular formula: C9H16N3O14P3 (free acid). Mole weight: 483.15 (free acid). | |
β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate Quick inquiry Where to buy Suppliers range | β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(Trihydrogen Diphosphate), P'?5'-Ester with 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium Hydroxide Sodium Salt Hydrate; Adenine-nicotinamide Dinucleotide Sodium Salt Hydrate; CO-I Sodium Salt Hydrate; Codehydrase I Sodium Salt Hydrate; Codehydrogenase I Sodium Salt Hydrate; Coenzyme I Sodium Salt Hydrate; Cozymase I Sodium Salt Hydrate; DPN Sodium Salt Hydrate; Diphosphopyridine Nucleotide Sodium Salt Hydrate; Enzopride Sodium Salt Hydrate; NAD Sodium Salt Hydrate; NAD+ Sodium Salt Hydrate; NSC 20272 Sodium Salt Hydrate; Nadide Sodium Salt Hydrate; Nicotinamide-adenine Dinucleotide Sodium Salt Hydrate; Oxidized diphosphopyridine Nucleotide Sodium Salt Hydrate; β-Diphosphopyridine Nucleotide Sodium Salt Hydrate; β-NAD Sodium Salt Hydrate; β-NAD+ Sodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7NaO14P2 X(H2O). Mole weight: 685.41. | |
Cdc25A (80-93) (human) Quick inquiry Where to buy Suppliers range | Cdc25A abundance fluctuates periodically during the cell division cycle and is mainly regulated by the ubiquitin-proteasome system, through the action of two ubiquitin ligase complexes, which later promote complex/cyclosome and Skp1/Cul1/F-box proteins. Due to the presence of the destruction motif (KEN-box) in Cdc25A, ubiquitination and degradation occur at the mitotic outlet and G1, while phosphorylation events modulate the stability of Cdc25A protein in the S phase, both in undisturbed cells and in cells exposed to DNA damage agents or DNA replication inhibitors. Synonyms: H-Thr-Asp-Ser-Gly-Phe-Cys-Leu-Asp-Ser-Pro-Gly-Pro-Leu-Asp-OH. Grades: ≥95%. CAS No. 851538-67-5. Molecular formula: C60H90N14O24S. Mole weight: 1423.52. | |
L189 Quick inquiry Where to buy Suppliers range | L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding. L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. Synonyms: L189; L 189; L-189. Grades: 98%. CAS No. 64232-83-3. Molecular formula: C11H10N4OS. Mole weight: 246.29. | |
L67 Quick inquiry Where to buy Suppliers range | L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC50 values of 10 μM and 10 μM.). Synonyms: L67; L-67; L 67. Grades: 98%. CAS No. 325970-71-6. Molecular formula: C16H14Br2N4O4. Mole weight: 486.12. | |
Mant-dATP Quick inquiry Where to buy Suppliers range | Mant-dATP is a vital tool acting as a modified form of deoxyadenosine triphosphate (dATP) labeled with the mant fluorophore. Mant-dATP is beneficial for studying various enzymatic activities, including DNA polymerases, DNA ligases and helicases, due to its ability to monitor nucleotide incorporation during DNA synthesis. Additionally, it plays a crucial role in investigating diseases related to DNA replication and repair mechanisms. Synonyms: 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyadenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 128113-53-1. Molecular formula: C18H23N6O13P3(free acid). Mole weight: 624.33 (free acid). | |
N6-(6-Amino)hexyl-dATP - 5-FAM Quick inquiry Where to buy Suppliers range | N6-(6-Amino)hexyl-dATP - 5-FAM, a fluorescently labeled nucleotide analog, finds its remarkable applicability in molecular biology for DNA synthesis, repair, and replication studies. One can efficiently detect polymerases, nicking enzymes, DNA ligases, and helicases, besides employing it in real-time PCR (polymerase chain reaction) and DNA sequencing. Remarkably, it can serve as a facile substrate for DNA polymerases in DNA synthesis reactions, making it a versatile compound paving new avenues for intriguing scientific pursuits. Synonyms: N; -(6-Amino)hexyl-2'-deoxyadenosine-5'-triphosphate, labeled with 5 FAM, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C37H39N6O18P3(free acid). Mole weight: 948.66 (free acid). | |
Nicotinic Acid Adenine Dinucleotide Quick inquiry Where to buy Suppliers range | Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide; a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(trihydrogen diphosphate), P'?5'-ester with 3-carboxy-1-β-D-ribofuranosylpyridinium, inner salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt; Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5'?5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt; 1: PN: WO2006081329 PAGE: 47 claimed sequence; Adenine-nicotinic Acid Dinucleotide; Codehydrogenase I, carboxy deamido analog; Codehydrogenase I, nicotinic acid analog; Deamido-NAD; Deamidodiphosphopyridine Nucleotide; Desamido NAD; Nicotinate Adenine Dinucleotide; Nicotinic Acid-adenine Dinucleotide. CAS No. 6450-77-7. Molecular formula: C21H26N6O15P2. Mole weight: 664.41. | |
NSC 207895 Quick inquiry Where to buy Suppliers range | NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. Synonyms: NSC 207895; NSC-207895; NSC207895; XI-006; XI006; XI 006. Grades: >98%. CAS No. 58131-57-0. Molecular formula: C11H13N5O4. Mole weight: 279.25. | |
Sarafloxacin hydrochloride Quick inquiry Where to buy Suppliers range | Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Synonyms: Sarafloxacin HCl; A-56620; A 56620; A56620. Grades: >98%. CAS No. 91296-87-6. Molecular formula: C20H17F2N3O3.HCl. Mole weight: 421.83. | |
SCR7 pyrazine Quick inquiry Where to buy Suppliers range | SCR7 pyrazine is a DNA Ligase IV inhibitor. SCR7 pyrazine has been shown to potentiate CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold, and inhibits nonhomologous end-joining (NHEJ). Synonyms: SCR7 pyrazine; SCR-7 pyrazine; SCR 7 pyrazine; 2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone; 2-mercapto-6,7-diphenylpteridin-4-ol; 6,7-diphenyl-2-sulfanylpteridin-4-ol. Grades: ≥98% by HPLC. CAS No. 14892-97-8. Molecular formula: C18H12N4OS. Mole weight: 332.38. | |
SCR7 Pyrazine Quick inquiry Where to buy Suppliers range | SCR7 pyrazine also is a potent inhibitor of nonhomologous endjoining (NHEJ) mediated by DNA ligase IV. It enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro upt to 19-fold. SCR7 pyrazine is a product of spontaneous cyclization of CRISPR enhancer SCR7 first reported by Srivastava, M., et al.DNA ligase IV seals double-strand breaks during the process of nonhomologous end-joining in DNA repair. Inhibiting this function in cancer cells is one strategy to prevent deleterious cell growth. SCR7 is a small molecule inhibitor of DNA ligase IV that prevents nonhomologous end-joining by interfering with ligase binding and activating apoptosis.1 It also inhibits ligase III, but does not affect the activity of T4 DNA ligase or ligase I. SCR7 has been used to increase the rate of homology directed repair triggered by DNA double-strand breaks and to inhibit cancer cell growth in vitro (IC50s = 8-120 µM) and in mouse models when co-administered with double-strand break-inducing therapeutic compounds.1,2,3,4. Group: Biochemicals. Alternative Names: 2,3-Dihydro-6,7-diphenyl-2-thioxo-4 (1H)-pteridinone; 6,7-Diphenyl-2-thio-lumazine. Grades: Highly Purified. CAS No. 14892-97-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS, Molecular Weight: 332.38. US Biological Life Sciences. | Worldwide |