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10 β-Desmethoxy-10 β-(4-methoxy-butoxy) Cabazitaxel is an impurity of the anti-mitotic agent Docetaxel (D494420) or the A microtubule inhibitor Cabazitaxel (C046500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C49H65NO15, Molecular Weight: 908.04. US Biological Life Sciences.
10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel is a derivative of baccatin III (B101000), an inhibitor of tubulin disassembly in human cancer cells and also the synthetic precursor of Paclitaxel (P132500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C58H72N2O18, Molecular Weight: 1085.19. US Biological Life Sciences.
10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2α, 5β, 7β, 10β, 13α)-4-Acetoxy-1-hydroxy-7, 13-bis{[(2R, 3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-10-methoxy-9-oxo-5, 20-epoxytax-11-en-2-yl benzoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,9-diyl ester, (αR,βS)-. Molecular formula: C58H72N2O18. Mole weight: 1085.19.
10-Methyl Docetaxel
10-Methyl Docetaxel is a metabolite of Docetaxel (D494420), a microtubule inhibitor that has the potential to be used in treating hormone refractory prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 160084-81-1. Pack Sizes: 5mg, 50mg. Molecular Formula: C44H55NO14, Molecular Weight: 821.91. US Biological Life Sciences.
Worldwide
10-Methyl Docetaxel-D3
10-Methyl Docetaxel-D3 is a labelled analogue of 10-methyl Docetaxel (M320020). Group: Biochemicals. Grades: Highly Purified. CAS No. 1383561-32-7. Pack Sizes: 1mg. Molecular Formula: C44H52D3NO14, Molecular Weight: 824.92. US Biological Life Sciences.
10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel is an impurity of Docetaxel Hydrate (D494420), a semisynthetic derivative of Paclitaxel(P132500), which is an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C52H69Cl2NO16Si, Molecular Weight: 1063.08999999999. US Biological Life Sciences.
10-(O-2,2-Dichloroethoxycarbonyl) 13-(3-O-TES) 7-Epi Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2α, 5β, 7α, 10β, 13α)-4-Acetoxy-10-{[(2, 2-dichloroethoxy)carbonyl]oxy}-1, 7-dihydroxy-13-({(2R, 3S)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenyl-2-[(triethylsilyl)oxy]propanoyl}oxy)-9-oxo-5, 20-epoxytax-11-en-2-yl benzoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-[(triethylsilyl)oxy]-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-6-[[(2,2-dichloroethoxy)carbonyl]oxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Molecular formula: C52H69Cl2NO16Si. Mole weight: 1063.09.
10-O-2,2-Dichloroethoxycarbonyl Docetaxel
10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 158810-73-2. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C46H55Cl2NO16. US Biological Life Sciences.
10-Oxo 20-seco-2'-Dehydro 7,8-seco-Docetaxel Acrylaldehyde Di-triethylsilane is an intermediate in synthesizing Docetaxel Crotonaldehyde Analog (D525620), an impurity of Docetaxel (D494420). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C55H79NO14Si2, Molecular Weight: 1034.39. US Biological Life Sciences.
Worldwide
10-Oxo 7,8-Seco-docetaxel
10-Oxo 7,8-seco-Docetaxel is an intermediate in synthesizing Docetaxel Crotonaldehyde Analog (D525620), an impurity of Docetaxel (D494420). Group: Biochemicals. Grades: Highly Purified. CAS No. 177556-02-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C43H53NO14, Molecular Weight: 807.88. US Biological Life Sciences.
Worldwide
10-Oxo 7,8-Seco-docetaxel Tri-triethylsilane
10-Oxo 7,8-seco-Docetaxel Tri-triethylsilane is an intermediate in synthesizing Docetaxel Crotonaldehyde Analog, an impurity of Docetaxel. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C61H95NO14Si3, Molecular Weight: 1150.66. US Biological Life Sciences.
Worldwide
10-Oxo Docetaxel
A novel taxoid having remarkable anti-tumor properties. Docetaxel. Group: Biochemicals. Grades: Highly Purified. CAS No. 167074-97-7. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
10-Oxo t-Butyldimethylsilyl 7-rac-Docetaxel
10-Oxo t-Butyldimethylsilyl 7-rac-Docetaxel is an intermediate in synthesizing Docetaxel Crotonaldehyde Analog (D525620), an impurity of Docetaxel (D494420). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C49H65NO14Si, Molecular Weight: 920.12. US Biological Life Sciences.
Worldwide
1,1-Diethoxy-2-methyl-2-propanol
1,1-Diethoxy-2-methyl-2-propanol is an intermediate in the synthesis of metabolites of docetaxel (D494420), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 108994-55-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H18O3. US Biological Life Sciences.
Worldwide
13,14-Anhydro-10-desacetyl Baccatin
13,14-Anhydro-10-desacetyl Baccatin is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: Docetaxel Impurity 24. CAS No. 1217248-58-2. Molecular formula: C29H34O9. Mole weight: 526.57.
An intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
13-O-(trans-3-Phenyl-glycidyl)-7,10-bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
Baccatin III derivative. Intermediate for the preparation of Docetaxel. Group: Biochemicals. Alternative Names: 13-O-(trans-3-Phenyloxirane-2-carboxylate)-7,10-bis[O-(triethylsilyl)]-10-deacetyl Baccatin III. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Intermediate in the preparation of Docetaxel Metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246819-38-4. Pack Sizes: 100mg. US Biological Life Sciences.
Intermediate in the preparation of labeled Docetaxel Metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246816-85-2. Pack Sizes: 10mg. US Biological Life Sciences.
2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) is an intermediate in the synthesis of 10-O-2,2-Dichloroethoxycarbonyl Docetaxel (D434415). 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an anti-neoplastic and anti-mitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C2H4Cl2O + C4H3Cl5O3 + C3H3Cl3O2, Molecular Weight: 114.96276331774. US Biological Life Sciences.
2-Desbenzoyl-2-pentonyl Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2α, 5β, 7β, 10β, 13α)-4-Acetoxy-1, 7, 10-trihydroxy-13-{[(2R, 3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5, 20-epoxytax-11-en-2-yl valerate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Molecular formula: C41H57NO14. Mole weight: 787.89.
2-Desbenzoyl-2-tiglyl Docetaxel
Docetaxel injection impurity A. Group: Biochemicals. Alternative Names: (2b,5b,7a,10b,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl (2E)-2-Methylbut-2-enoate; Docetaxel Impurity A. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
2-Methyl-1-(4-methoxyphenyl)methoxy-2-propanol-d6 is an intermediate in the synthesis of Docetaxel Hydroxy tert-Butylcarbamate-d6 (D494427), which is is the labeled analogue of Docetaxel Hydroxy tert-Butylcarbamate (D494425), the main metabolite of Docetaxel (D494420), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H12D6O3. US Biological Life Sciences.
2-[Methyl-1- (4-methoxyphenyl) methoxy]propyl-4-nitrophenyl-d6 Carbonate is an intermediate in the synthesis of Docetaxel Hydroxy tert-Butylcarbamate-d6 (D494427), which is is the labeled analogue of Docetaxel Hydroxy tert-Butylcarbamate (D494425), the main metabolite of Docetaxel (D494420), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H15D6NO7. US Biological Life Sciences.
Worldwide
2'-Oxo Docetaxel
2'-Oxo Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Molecular formula: C43H51NO14. Mole weight: 805.86.
2-Oxo Docetaxel
2-Oxo Docetaxel is an impurity of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C43H51NO14, Molecular Weight: 805.86. US Biological Life Sciences.
Worldwide
2R,3R-Docetaxel
2R,3R-Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid Derivative; R-Erythro-taxotere; 3'-epi-docetaxel; 3'(S)-Docetaxel; Paclitaxel Impurity 62; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βR)-; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα, 4β, 4aβ, 6β, 9α(αR*, βR*), 11α, 12α, 12aα, 12bα]]-. Grades: ≥90%. CAS No. 133577-32-9. Molecular formula: C43H53NO14. Mole weight: 807.88.
(2S,3R)-3-Phenyl Isoserine Methyl Ester Hydrochloride acts as a reagent for the synthesis of Docetaxel and its isomers in high yields, which are know for cancer treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H13NO3; HCl, Molecular Weight: 195.223598. US Biological Life Sciences.
Worldwide
2'-Triethylsilyldocetaxel
Used in the preparation of ester-linked docetaxel-monosaccharide conjugates. Group: Biochemicals. Alternative Names: (αR, βS)- β -[[ (1, 1-Dimethylethoxy) carbonyl]amino]-α -[ (triethylsilyl) oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 6, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 162871-12-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
3-Deoxy-3-acetyl abiraterone-3-ene
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethanone. Grades: 95%. Molecular formula: C26H31NO. Mole weight: 373.54.
3-Deoxy 3-chloroabiraterone
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-((8R,9S,10R,13S,14S)-3-Chloro-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grades: 95%. Molecular formula: C24H30ClN. Mole weight: 367.95.
(3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3R,4S)-1-T-BUTOXYCARBONYL-3-ACETOXY-4-PHENYL-2-AZETIDINONE;(3R,4S)-1-TERT-BUTOXYCARBONYL-3-ACETOXY-4-PHENYL-2-AZETIDINONE;(3R,4S)-1-T-Butoxycarbonyl-3-A;(3R,4S)-1-T-BUTOXYCARBONYL-3-ACETOXY -4-PHENYL-2-AZETIDINONE,98+%;SIDE CHAINS OF DOCETAXEL--3. Product Category: Heterocyclic Organic Compound. CAS No. 161183-22-8. Molecular formula: C16H19NO5. Mole weight: 305.33. Purity: 0.96. IUPACName: tert-butyl (3R,4S)-3-acetyloxy-2-oxo-4-phenylazetidine-1-carboxylate. Canonical SMILES: CC(=O)OC1C(N(C1=O)C(=O)OC(C)(C)C)C2=CC=CC=C2. Density: 1.237 g/cm³. Product ID: ACM161183228. Alfa Chemistry ISO 9001:2015 Certified.
(3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone
Docetaxel or Paclitaxel intermediate. Group: Biochemicals. Alternative Names: (3R-cis)-3-Hydroxy-4-phenyl-2-azetidinone. Grades: Highly Purified. CAS No. 132127-34-5. Pack Sizes: 250mg. US Biological Life Sciences.
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DOCETAXEL SIDE CHAIN NO 2;(3R,4S)-TERT-BUTYL 2-OXO-4-PHENYL-3-(TRIETHYLSILYLOXY)AZETIDINE-1-CARBOXYLATE;(3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester;(3r,4s)-1-Azetidine Carboxylic Acid-2-Oxo-4-Phenyl-3-. Product Category: Heterocyclic Organic Compound. Appearance: Syrup. CAS No. 149198-47-0. Molecular formula: C20H31NO4Si. Mole weight: 377.55. Density: 1.07. Product ID: ACM149198470. Alfa Chemistry ISO 9001:2015 Certified.
6-Oxo-7-epi Docetaxel
6-Oxo-7-epi Docetaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C43H51NO15. Mole weight: 821.86.
7, 10, 13-tri -O-tri chloroethoxycarbonyl-10-deacetyl Baccatin III
A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
Intermediate for the preparation of Docetaxel. Group: Biochemicals. Alternative Names: (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b- (Acetyloxy)-12- (benzoyloxy)-1, 2a, 3, 4, 4a, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-9, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-4, 6-bis[ (triethylsilyl)oxy]-7, 11-methano-5H-cyclodeca[3, 4]benz[1, 2-b]oxet-5-one. Grades: Highly Purified. CAS No. 149107-84-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Intermediate for the preparation of isotope Labeled Docetaxel. Group: Biochemicals. Alternative Names: (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b- (Acetyloxy)-12- (benzoyloxy)-1, 2a, 3, 4, 4a, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-9, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-4, 6-bis[ (triethylsilyl)oxy]-7, 11-methano-5H-cyclodeca[3, 4]benz[1, 2-b]oxet-5-one-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
7, 10-Di-O-tri chloroethoxycarbonyl-10-deacetyl Baccatin III
A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Labeled Docetaxel derivative as antitumor agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
7-epi-10-Oxo-10-deacetyl Baccatin III
7-epi-10-Oxo-10-deacetyl Baccatin III is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2aR,4R,4aS,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,9,10,11,12,12a,12b-decahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,6-dione; 10-Deacetyl-10-oxo-baccatin V; 10-Dehydrobaccatin V; Docetaxel Impurity 20; 7-epi-10-oxo-10-DAB. Grades: 97%. CAS No. 151636-94-1. Molecular formula: C29H34O10. Mole weight: 542.57.
7-Epi-10-oxo Docetaxel
Docetaxel injection. Group: Biochemicals. Alternative Names: (2b,5b,7a,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7-dihydroxy-9,10-dioxo-5,20-epoxytax-11-en-2-yl Benzoate. Grades: Highly Purified. CAS No. 162784-72-7. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
7-Epi Docetaxel
An isomer of Docetaxel. Docetaxel injection. Group: Biochemicals. Alternative Names: (2b,5b,7a,10b,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl Benzoate; 7-Epidocetaxel; 7-Epitaxotere. Grades: Highly Purified. CAS No. 153381-68-1. Pack Sizes: 1mg. US Biological Life Sciences.
7-Methyl-10-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel is a derivative of is a derivative of baccatin III. Synonyms: 7-Methyl-10-(2-Hydroxy-3-N-Boc-3-Phenylpropionyl) Docetaxel; 1714967-25-5. Grades: > 95%. CAS No. 1714967-25-5. Molecular formula: C58H72N2O18. Mole weight: 1085.19.
7-Methyl Docetaxel
7-Methyl Docetaxel is a metabolite of Docetaxel. Synonyms: (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4-methoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-me. Grades: > 95%. CAS No. 1420767-25-4. Molecular formula: C44H55NO14. Mole weight: 821.91.
7-Oxo Docetaxel
7-Oxo Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Molecular formula: C43H51NO14. Mole weight: 805.86.
α-Epoxyabiraterone acetate
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: (4S, 6aR, 6bS, 8aS, 8bR, 9aR, 10aS, 10bR)-6a, 8a-Dimethyl-8b-(pyridin-3-yl)-3, 4, 5, 6, 6a, 6b, 7, 8, 8a, 8b, 9a, 10, 10a, 10b-tetradecahydro-1H-naphtho[2', 1':4, 5]indeno[1, 2-b]oxiren-4-yl Acetate. Grades: 95%. Molecular formula: C26H33NO3. Mole weight: 407.55.
Anhydro abiraterone
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. Grades: 95%. CAS No. 154229-20-6. Molecular formula: C24H29N. Mole weight: 331.49.
Cabazitaxel Impurity (DiTroc)
A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic. Synonyms: Carbonic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,6-diyl bis(2,2,2-trichloroethyl) E. Grades: > 95%. CAS No. 95603-44-4. Molecular formula: C35H38Cl6O14. Mole weight: 895.4.
CG200745
CG200745 is a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI). Like other inhibitors, CG200745 has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. CG200745 inhibited deacetylation of histone H3 and tubulin as much as vorinostat and belinostat did. CG200745 also inhibited growth of prostate cancer cells, increased sub-G1 population, and activated caspase-9, -3 and -8 in LNCaP, DU145 and PC3 cells. These results indicate that CG200745 induces apoptosis. The preclinical results show that combination treatment with docetaxel and new HDACI, CG200745, potentiated anti-tumor effect in hormone-refractory prostate cancer (HRPC) cells via activation of apoptosis. Synonyms: Ivaltinostat; CG-200745; CG-2; (E)-N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalen-1-yloxy)methyl)oct-2-enediamide. CAS No. 936221-33-9. Molecular formula: C24H33N3O4. Mole weight: 427.55.
CYP1B1-IN-7
CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 ( IC 50 : 75 nM). CYP1B1-IN-7 also reverses resistance ( IC 50 : 29 μM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel (HY-B0011) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52601-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-157942.
Desbenzoyl Docetaxel
Desbenzoyl Docetaxel. Group: Biochemicals. Grades: Highly Purified. CAS No. 160972-48-5. Pack Sizes: 5mg. Molecular Formula: C36H49NO13, Molecular Weight: 703.77. US Biological Life Sciences.
Worldwide
Desbenzoyl Docetaxel
Desbenzoyl Docetaxel is an impurity of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2α, 5β, 7β, 10β, 13α)-4-Acetoxy-1, 2, 7, 10-tetrahydroxy-9-oxo-5, 20-epoxytax-11-en-13-yl (2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11,12-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα, 4β, 4aβ, 6β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11,12-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Grades: ≥90%. CAS No. 160972-48-5. Molecular formula: C36H49NO13. Mole weight: 703.77.
Docetaxel
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C43H53NO14. CAS No. 114977-28-5. Prepack ID 75180981-100mg. Molecular Weight 807.88. See USA prepack pricing.
Docetaxel
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C43H53NO14. CAS No. 114977-28-5. Prepack ID 75180981-1g. Molecular Weight 807.88. See USA prepack pricing.
Docetaxel
500mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C43H53NO14. CAS No. 114977-28-5. Prepack ID 75180981-500mg. Molecular Weight 807.88. See USA prepack pricing.
Docetaxel
An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin. Docetaxel is of the chemotherapy drug class; taxane, and is a semi-synthetic analogue of paclitaxel (Taxol), an extract from the bark of the rare Pacific yew tree Taxus brevifolia. Due to scarcity of paclitaxel, extensive research was carried out leading to the formulation of docetaxel - an esterified product of 10-deacetyl baccatin III, which is extracted from the renewable and more readily available leaves of the European yew tree. Group: Biochemicals. Alternative Names: Docecad; N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol; NSC 628503; RP 56976; Taxoltere metro; docetaxol; Taxotere. Grades: Highly Purified. CAS No. 114977-28-5. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Docetaxel
Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC 50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity [1] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: RP-56976. CAS No. 114977-28-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0011.
Docetaxel
Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TAXOTERE;n-debenzoyl-n-tert-butoxycarbonyl-10-deacetyl taxol;)benz(1,2-b)oxet-9-ylester,(2ar-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alph;-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydr;benzenepropanoicacid,beta-(((1,1-dimethylethoxy)carbonyl)amino)-alpha-hydroxy;beta-s*),11-alpha,12-alpha,12a-alpha,12b-alpha))-a-r;o-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1h-cyclodeca(3,4;rp56976. Product Category: Inhibitors. Appearance: Solid. CAS No. 114977-28-5. Molecular formula: C43H53NO14. Mole weight: 807.88. Purity: 0.9942. Canonical SMILES: O=C(OC(C)(C)C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](O)C([C@@]3(C)[C@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O. Product ID: ACM114977285-1. Alfa Chemistry ISO 9001:2015 Certified.
Docetaxel
N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl Taxol. CAS No. 114977-28-5. Product ID: 8-01305. Molecular formula: Purity: 0.975. Source : ex Taxus brevifolia. Reference:
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