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1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C50H74O14. CAS No. 117704-25-3. Prepack ID 48672805-1g. Molecular Weight 899.11. See USA prepack pricing.
Doramectin
25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin. CAS No. 117704-25-3. Product ID: 2-08527. Molecular formula: C50H74O14. Mole weight: 899.11. Purity: 0.95. Source : veterinary use anti-parasitic.
Doramectin
Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Doramectin
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 117704-25-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17035.
Doramectin
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN;DORAMECTIN;Doramectin VETRANAL;Doromectin;_x00B_25-Cclohexyl-avermectin B1;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A;Dectoma;UK-67994. Product Category: Inhibitors. Appearance: Solid. CAS No. 117704-25-3. Molecular formula: C50H74O14. Mole weight: 899.11. Purity: 0.9896. Canonical SMILES: CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]\7(O)[C@@]4([H])C=C(C)[C@H]8O)C1. Product ID: ACM117704253. Alfa Chemistry ISO 9001:2015 Certified.
Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Alternative Names: 25-Cyclohexyl-5-O-demethyl-25-de (1-methylpropyl) avermectin A1A; 25-Cylohexyl-avermectin B1; UK-67994; Dectomax. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Doramectin aglycone
It is an acid degradation product produced by hydrolysis of the disaccharide unit of doramectin. It is an inhibitor of nematode larval development and an anthelmintic in animal health. It has no paralytic activity. Synonyms: 25R-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6R,28-epoxy-13S-hydroxy-milbemycin B. Grades: >95% by HPLC. CAS No. 1987883-26-0. Molecular formula: C36H50O8. Mole weight: 610.78.
Doramectin Impurity 1
Doramectin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H76O15. Mole Weight: 917.13. Catalog: APB05513.
Doramectin Impurity 2
Doramectin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Doramectin Impurity 2. CAS No. 65195-56-4. Molecular Formula: C47H70O14. Mole Weight: 859.05. Catalog: APB65195564.
Doramectin Impurity 3
Doramectin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Doramectin Impurity 3. CAS No. 65195-55-3. Molecular Formula: C48H72O14. Mole Weight: 873.08. Catalog: APB65195553.
Doramectin Impurity 4
Doramectin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H76O14. Mole Weight: 901.13. Catalog: APB05512.
Doramectin Impurity 5
Doramectin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H72O14. Mole Weight: 885.09. Catalog: APB05511.
Doramectin Impurity 6
Doramectin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H74O14. Mole Weight: 899.11. Catalog: APB05509.
Doramectin Impurity 7
Doramectin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C51H76O14. Mole Weight: 913.14. Catalog: APB05510.
Doramectin monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is a potent inhibitor of nematode larval development and an anthelmintic in animal health. Synonyms: 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a. Grades: >95% by HPLC. CAS No. 165108-44-1. Molecular formula: C43H62O11. Mole weight: 754.95.
Doramectin (Standard)
Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 117704-25-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17035R.
delta2-Doramectin
An irreversible base degradation product of doramectin found in animals treated with doramectin and in the environment. It is formed by rearrangement of the naturally occurring 3-group in doramectin to the 2-position. It is an anthelmintic in animal health. Synonyms: (4S)-25-cyclohexyl-2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-3,4-dihydro-avermectin A1a; Doramectin, delta2-; Δ2-Doramectin. Grades: >95% by HPLC. CAS No. 1987882-63-2. Molecular formula: C50H74O14. Mole weight: 899.11.
It is a base-catalysed intermediate in the decomposition of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Synonyms: (2S)-25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a; Doramectin, epi-. Grades: >95% by HPLC. CAS No. 1987882-62-1. Molecular formula: C50H74O14. Mole weight: 899.11.
Epidoramectin Aglycone
It is a base-catalysed intermediate produced by hydrolysis of the disaccharide unit of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Synonyms: 2-Epidoramectin Aglycone. Molecular formula: C36H50O8. Mole weight: 610.78.
Epidoramectin Monosaccharide
It is a base-catalysed intermediate produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Synonyms: 2-Epidoramectin Monosaccharide. Molecular formula: C43H62O11. Mole weight: 754.94.
Duramycin
Duramycin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ancovenin,2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-,cyclic 6-19)-imine; LANCOVUTIDE; Leucopeptin; UNII-BPR0F3X56H; Lancovutide [INN]. CAS No. 1391-36-2. Molecular formula: C89H125N23O25S3. Mole weight: 2013.28. Purity: 90+%. IUPACName: Duramycin. Canonical SMILES: CC1C2C(=O)NC(C(=O)NC(C(=O)NC3CSCC4C(=O)NC(CS1)C(=O)NC(CNCCCCC(NC(=O)C(CSCC(C(=O)NC(C(=O)NC(C(=O)N4)CCC(=O)N)CCCCN)N)NC(=O)C(NC(=O)CNC(=O)C(NC3=O)C(C(=O)O)O)CC(=O)N)C(=O)O)C(=O)NC(C(=O)NCC(=O)N5CCCC5C(=O)NC(C(=O)N2)CC6=CC=CC=C6)CC7=CC=CC=C7)C(C)C)CC8=CC=CC=C8. Product ID: ACM1391362. Alfa Chemistry ISO 9001:2015 Certified. Categories: Doramectin.
Selamectin Impurity D
An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a; 22,23-Dihydro-5-hydroxyimino Doramectin; 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin. Grades: > 95%. CAS No. 301849-46-7. Molecular formula: C50H75NO14. Mole weight: 914.15.
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