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Doxazosin is a quinazoline-derivative and long-lasting α1 adrenergic receptor blocker. It inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. It is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms. It may have an inhibitory effect on cholesterol synthesis independent of the LDL receptor. It also shows high affinity to alpha-1c adrenoceptor which may partially attribute to its effect in treatment of benign prostatic hyperplasia. It has been found to help reduce the intensity of and/or stop posttraumatic stress disorder night terrors and nightmares. Synonyms: [4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-(2,5-dioxabi cyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone; Piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-; UK 33274; Doxazosin; Cardura; Alfamedin. Grades: 98%. CAS No. 74191-85-8. Molecular formula: C23H25N5O5. Mole weight: 451.48.
Doxazosin
Doxazosin (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Uses: Scientific research. Group: Natural products. Alternative Names: UK 33274. CAS No. 74191-85-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0098.
Doxazosin-d8
Labeled Doxazosin, a selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Doxazosin EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(piperazine-1,4-diyl)bis(6,7-dimethoxyquinazolin-4-amine). CAS No. 102839-00-9. Molecular formula: C24H28N8O4. Mole weight: 492.53. Catalog: APB102839009.
Doxazosin Impurity 10
Doxazosin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(6-hydroxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone. CAS No. 102932-28-5. Molecular formula: C23H25N5O6. Mole weight: 467.47. Catalog: APB102932285.
Doxazosin Impurity 9
Doxazosin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(4-amino-6-hydroxy-7-methoxyquinazolin-2-yl)piperazin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone. CAS No. 102932-26-3. Molecular formula: C22H23N5O5. Mole weight: 437.45. Catalog: APB102932263.
Doxazosin mesilate
Doxazosin mesilate. Group: Biochemicals. Alternative Names: UK-33274-27; Alfadil; Cardenalin. Grades: Highly Purified. CAS No. 77883-43-3. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C24H29N5O8S. US Biological Life Sciences.
Doxazosin mesylate. Group: Biochemicals. Grades: Purified. CAS No. 77883-43-3. Pack Sizes: 50mg. US Biological Life Sciences.
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Doxazosin mesylate
Doxazosin mesylate (UK 33274 mesylate) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 33274 mesylate. CAS No. 77883-43-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0098A.
Doxazosin Mesylate
Doxazosin mesylate is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. Grades: >98%. CAS No. 77883-43-3. Molecular formula: C24H29N5O8S. Mole weight: 547.58.
A selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: UK-33274-27, Alfadil, Cardenalin. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
6-Hydroxy doxazosin. Group: Biochemicals. Alternative Names: 1-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl-piperazine. Grades: Highly Purified. CAS No. 102932-26-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H23N5O5. US Biological Life Sciences.
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6'-Hydroxy doxazosin
6'-Hydroxy doxazosin. Group: Biochemicals. Alternative Names: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-6-hydroxy-1,4-benzodioxin-2-yl)carbonyl-piperazine. Grades: Highly Purified. CAS No. 102932-29-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C23H25N5O6. US Biological Life Sciences.
Worldwide
7-Hydroxy doxazosin
7-Hydroxy doxazosin. Group: Biochemicals. Alternative Names: 1-(4-Amino-7-hydroxy-2-methoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl-piperazine. Grades: Highly Purified. CAS No. 102932-25-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H23N5O5. US Biological Life Sciences.
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R-Doxazosin
(R)-Doxazosin is an Isomer of Doxazosin Mesylate. Synonyms: (R)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine. Grades: > 95%. CAS No. 70918-17-1. Molecular formula: C23H25N5O5. Mole weight: 451.49.
S-Doxazosin
(S)-(+)-Doxazosin is an Isomer of Doxazosin Mesylate. Synonyms: (S)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]carbonyl]piperazine. Grades: > 95%. CAS No. 104874-86-4. Molecular formula: C23H25N5O5. Mole weight: 451.48.
1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine-d8
A labeled intermediate of Doxazosin. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1,4-benzodioxin-2-yl)-1-piperazinyl-d8-methanone;1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine-d8. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate. Group: Biochemicals. Grades: Highly Purified. CAS No. 70918-74-0. Pack Sizes: 1g, 2g. Molecular Formula: C13H17ClN2O3. US Biological Life Sciences.
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