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| Product | Description | |
|---|---|---|
| Dynorphin (1-17) | Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Synonyms: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grades: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51. |  |
| Dynorphin A | Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 80448-90-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1333. |  |
| Dynorphin A 1-10 | Dynorphin A 1-10 is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with IC50 of 42.0 μM. Synonyms: Dynorphin A, porcine, fragment 1-10; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline; Dynorphin A (1-10), porcine. Grades: ≥95%. CAS No. 79994-24-4. Molecular formula: C57H91N19O12. Mole weight: 1234.45. | |
| Dynorphin A 1-10 acetate | Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Synonyms: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grades: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53. | |
| Dynorphin A (1-13) | Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grades: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95. | |
| Dynorphin A (1-13) amide | Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Synonyms: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grades: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97. | |
| Dynorphin A (1-17) (Kappa Opioid Receptor Agonist) | An endogenous agonist for kappa opioid receptors. Involved in several neurological disorders, including neuropathic pain, stress, depression, and Alzheimer's and Parkinson's diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 80448-90-4. Pack Sizes: 500ug, 1mg, 5mg, 10mg. Molecular Formula: C99H155N31O23, Molecular Weight: 2147.5. US Biological Life Sciences. |  Worldwide |
| Dynorphin A (1-8) | Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Synonyms: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grades: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15. | |
| Dynorphin A (1-8) | Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC 50 =303 nM) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 75790-53-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P2159. | |
| Dynorphin A acetate | Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58. | |
| Dynorphin B 1-13 | Dynorphin B is a 13-residue opioid peptide, which is derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an opioid peptide and a κ-opioid receptor agonists. It has been implicated in antinociceptive functions. It has also been used to prime cardiogenesis in pluripotent embryonic stem cells. Synonyms: Prodynorphin (226-238) (human); Prodynorphin (228-240) (porcine); Rimorphin; Dynorphin B 1-13; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonine. Grades: ≥95%. CAS No. 83335-41-5. Molecular formula: C74H115N21O17. Mole weight: 1570.84. | |
| Dynorphin B (1-9) trifluoroacetate salt | Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. Dynorphin B (1-9) is a competitive inhibitor of dynorphin A (1-9). Grades: ≥95%. Molecular formula: C54H78N16O12·xCF3COOH. Mole weight: 1143.30. | |
| (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) | (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) is a highly stable dynorphin-like analgesic peptide. Synonyms: E-2078; E2078; 1-N-Me-Tyr(1)-7-N-Me-arg-8-N-Et-leunh2-dynorphin(1-8); Dynorphin(1-8), N-Me-tyr(1)-N-Me-arg(7)-N-Et-leunh2(8)-; Dynorphin(1-8), N-methyltyrosyl(1)-N-methylarginyl(7)-N-ethylleucinamide(8)-; N-Me-Tyr-Gly-Gly-Phe-Leu-Arg-N-Me-Arg-D-Leu-NHEt; N-methyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-N-methyl-L-arginyl-D-leucine ethylamide; N-Me-Tyr-gly-gly-phe-leu-arg-N-Me-arg-leu-NH-C2H5. Grades: ≥90%. CAS No. 103613-84-9. Molecular formula: C50H81N15O9. Mole weight: 1036.29. | |
| Porcine dynorphin A(1-13) | Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Uses: Scientific research. Group: Peptides. Alternative Names: Dynorphin A Porcine Fragment 1-13. CAS No. 72957-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0088. | |
| Porcine dynorphin A (1-13) acetate | Porcine dynorphin A(1-13) acetate is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13 acetate; Dynorphin A (1-13) acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine acetic acid; Dynorphin A (swine), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); Dynorphin A (pig), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); 1-13-Dynorphin A (swine) acetate. Grades: ≥95%. Molecular formula: C77H130N24O17. Mole weight: 1664.00. | |
| Allomatrine | Sourced from herbs of Sophora alopecuroides L. Either (+)-matrine or (+)-Allomatrine when given i.c.v. may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord, and this phenomenon in turn produces the antinociception in mice. Allomatrine is a natural compound used in cosmetics material. Uses: Inhibit the central nervous anti-inflammatory. Synonyms: 6-Allomatrine; Tetrahydroisosophoramine. Grades: >98%. CAS No. 641-39-4. Molecular formula: C15H24N2O. Mole weight: 248.36. | |
| H-Tyr-gly-gly-phe-leu-D-arg-arg-ile-arg-pro-lys-leu-lys-oh | H-Tyr-gly-gly-phe-leu-D-arg-arg-ile-arg-pro-lys-leu-lys-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS;YGGFLD-RRIRPKLK;(D-ARG6)-DYNORPHIN A (1-13);[D-ARG6]-DYNORPHIN A (1-13), PORCINE;DYNORPHIN A PORCINE [D-ARG6]-FRAGMENT 1-13;H-TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-OH;dynorphin A D-arg. Product Category: Heterocyclic Organic Compound. CAS No. 75921-87-8. Molecular formula: C75H126N24O15. Mole weight: 1603.95. Purity: 0.96. IUPACName: 6-amino-2-[[2-[[6-amino-2-[[1-[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)p. Product ID: ACM75921878. Alfa Chemistry ISO 9001:2015 Certified. |  |
| neurolysin | No absolute requirement for a prolyl bond: the enzyme acts on some peptides, such as dynorphin 1-8, that do not contain proline, and does not act on some others that do. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Enzyme Commission Number: EC 3.4.24.16. CAS No. 149371-24-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4297; neurolysin; EC 3.4.24.16; 149371-24-4; neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Cat No: EXWM-4297. |  |
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