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Echinocandin B is the major analogue of a family of lipopeptides isolated from several species of Aspergillus, reported in 1974. Echinocandin B is a potent antifungal and acts by inhibition of the synthesis of b(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 54651-05-7. Pack Sizes: 1mg. US Biological Life Sciences.
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Echinocandin B
It is produced by the strain of Aspergillus rugulosus. Echinocandin can inhibit (1,3)-β-Glucan synthase, an essential component of the cell wall of susceptible fungi, and has anti-fungal activity against candida. Synonyms: NSC 287461; 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-[(9Z,12Z)-octadeca-9,12-dienoyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline}; Antibiotic A 22082; Antibiotic A 30912 factor A; Antibiotic A 30912A; Antibiotic SL 7810; Antibiotic SL 7810F. Grade: >95% by HPLC. CAS No. 54651-05-7. Molecular formula: C52H81N7O16. Mole weight: 1060.23.
1-?[(4R,?5R)?-?4,?5-?dihydroxy-?L-?ornithine]?-Echinocandin B
1-[(4R,?5R)?-4,?5-dihydroxy-L-ornithine]?-Echinocandin B is an intermediate of Anidulafungin, an echinocandin antifungal drug. Synonyms: Echinocandin B nucleus; (2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-9-Amino-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methylhexadecahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosine-5,8,14,19,22,25(9H,25aH)-hexone; Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-. Grade: 95%. CAS No. 79411-15-7. Molecular formula: C34H51N7O15. Mole weight: 797.81.
1-?[(4R,?5R)?-?4,?5-?Dihydroxy-?L-?ornithine]?-Echinocandin B
Echinocandin B is a lipopeptide antifungal agent produced by several species of Aspergillus. Group: Biochemicals. Grades: Highly Purified. CAS No. 79411-15-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C34H51N7O15. US Biological Life Sciences.
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1-?[(4R,?5R)?-?4,?5-?Dihydroxy-?L-?ornithine]?-Echinocandin B Hydrochloride
1-[(4R,?5R)?-4,?5-Dihydroxy-L-ornithine]?-Echinocandin B Hydrochloride is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Synonyms: ECBN hydrochloride; ECBN HCL; A-30912A nucleus (hydrochloride). CAS No. 1029890-89-8. Molecular formula: C34H52ClN7O15. Mole weight: 834.27.
1-?[(4R,?5R)?-?4,?5-?Dihydroxy-?L-?ornithine]?-Echinocandin B Hydrochloride
1-?[(4R,?5R)?-?4,?5-?Dihydroxy-?L-?ornithine]?-Echinocandin B Hydrochloride is used in the commercialization and late-stage development of a semisynthetic antifungal anidulafungin/D-fructose. Group: Biochemicals. Grades: Highly Purified. CAS No. 1029890-89-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C34H51N7O15; HCl, Molecular Weight: 797.813645999999. US Biological Life Sciences.
Worldwide
Tetrahydroechinocandin B
Tetrahydroechinocandin B, a cyclic hexapeptide containing a fatty acyl side chain, inhibits 1,3-beta-D-glucan synthesis. It is an intermediate of anidulafungin. Synonyms: Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-N2-(1-oxooctadecyl)-L-ornithine]-; Echinocandin B, tetrahydro-; L 687,901; Octadecanimidic acid, N-[(2R,6S,7E,9S,11R,12R,14aS,15S,16S,20S,23R,24E,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,3,5,6,9,10,11,12,14a,15,16,17,19,20,23,25a-hexadecahydro-2,8,11,12,14,15,22,25-octahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,19-dioxo-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosin-9-yl]-; L-687901. Grade: 95% by HPLC. CAS No. 54651-06-8. Molecular formula: C52H85N7O16. Mole weight: 1064.27.
1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. CAS No. 198706-35-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C56H84N8O16S. US Biological Life Sciences.
1-[(4R,5R)-N2-(10,12-Dimethyl-N-tetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C56H86N8O15S. US Biological Life Sciences.
1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. CAS No. 935739-50-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C56H87ClN8O15S. US Biological Life Sciences.
Worldwide
Aminocandin
Aminocandin, a new representative of the echinocandins, has broad-spectrum in vitro activity against Aspergillus and Candida spp. It is used as an anti-infective agent and antifungal drug. It acts by targeting glucans in the fungal cell walls. Synonyms: IP960; HMR3270; NXL201; L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)-; N-[(2R,6S,9S,14aS,15S,16S,20S,23S,25aS)-11-[(2-Aminoethyl)amino]-2,15-dihydroxy-6-[(1R)-1-hydroxyethyl]-23-[(1R)-1-hydroxy-2-(4-hydroxyphenyl)ethyl]-20-(hydroxymethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl]-4'-(octyloxy)-4-biphenylcarboxamide. Grade: 95% by HPLC. CAS No. 227472-48-2. Molecular formula: C56H79N9O14. Mole weight: 1102.28.
Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug. Synonyms: Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B. Grade: >98%. CAS No. 166663-25-8. Molecular formula: C58H73N7O17. Mole weight: 1140.24.
Anidulafungin
Glucan synthase inhibitor. Anidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of - - -(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Group: Biochemicals. Alternative Names: 1-[(4R, 5R)-4, 5-dihydroxy-N2-[[4''-(pentyloxy)[1, 1':4', 1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B; LY 303366; Ecalta; Eraxis. Grades: Highly Purified. CAS No. 166663-25-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C58H73N7O17, Molecular Weight: 1140.25. US Biological Life Sciences.
Worldwide
Anidulafungin-d11
Anidulafungin-d11 is a labelled Anidulafungin. Anidulafungin is a semi-synthetic echinocandin used as an antifungal drug. It acts via inhibiting glucan synthase. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]echinocandin B-d11; Ecalta-d11; Eraxis-d11; LY 303366-d11. Grade: > 95%. Molecular formula: C58H62N7O17D11. Mole weight: 1151.33.
Anidulafungin Impurity 3
Anidulafungin Impurity 3 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Synonyms: 4-[4-(4-pentoxyphenyl)phenyl]benzoic acid; 4-[4-(4-pentoxyphenyl)phenyl]benzoic acid. Grade: ≥95%. CAS No. 158938-08-0. Molecular formula: C24H24O3. Mole weight: 360.45.
Anidulafungin Impurity A
Anidulafungin Impurity A is a degradation impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Synonyms: Anidulafungin Open-chain Degradant. Molecular formula: C58H73N7O17. Mole weight: 1140.25.
Anidulafungin Impurity B
Anidulafungin Impurity B is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity C
Anidulafungin Impurity C is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity D
Anidulafungin Impurity D is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C59H75N7O17. Mole weight: 1154.28.
Anidulafungin Impurity E
Anidulafungin Impurity E is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity F
Anidulafungin Impurity F is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C82H95N7O19. Mole weight: 1482.69.
Biafungin acetate
Biafungin acetate is a next-generation, broad-spectrum, and long-lasting echinocandin. It shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. Synonyms: Rezafungin acetate; CD101 acetate; CD-101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Molecular formula: C65H88N8O19. Mole weight: 1285.44.
Caspofungin Acetate
An echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate; Cancidas; Caspofungin Diacetate; L 743872; L 743873; MK 0991; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate. Grades: Highly Purified. CAS No. 179463-17-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N??O??, Molecular Weight: 1213.42. US Biological Life Sciences.
Worldwide
Caspofungin Acetate-d4
Isotope labelled Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate-d4; Cancidas-d4; Caspofungin Diacetate-d4; L 743872-d4; L 743873-d4; MK 0991-d4; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate-d4. Grades: Highly Purified. CAS No. 1131958-73-0, Unlabelled: 179463-17-3. Pack Sizes: 500ug. Molecular Formula: C??H??D?N??O??, Molecular Weight: 1217.44. US Biological Life Sciences.
Worldwide
Caspofungin Impurity A
Caspofungin Impurity A, is a metabolite of Caspofungin, which is an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall, and thus used as an antifungal drug. Synonyms: (3S)-(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithyl-L-seryl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-ornithyl-3-hydroxy-L-proline; EX-A3042. Grade: 90%. CAS No. 1202167-57-4. Molecular formula: C51H86N10O15. Mole weight: 1097.31.
Caspofungin Impurity B
Caspofungin Impurity B is the primary degradation product of Caspofungin, an antifungal agent in echinocandin class. Caspofungi is effective against infections with Aspergillus and Candida and functions via inhibiting β(1,3)-D-Glucan of the fungal cell wall. Molecular formula: C52H88N10O15. Mole weight: 1093.31.
Caspofungin Impurity C
Caspofungin Impurity C is a degradation product of Caspofungin, an antifungal agent in echinocandin class. Caspofungi is effective against infections with Aspergillus and Candida and functions via inhibiting β(1,3)-D-Glucan of the fungal cell wall. CAS No. 251095-73-5. Molecular formula: C52H88N10O15. Mole weight: 1093.31.
Caspofungin Impurity D
Caspofungin Impurity D is an impurity of Caspofungin, an antifungal agent in echinocandin class. Caspofungi is effective against infections with Aspergillus and Candida and functions via inhibiting β(1,3)-D-Glucan of the fungal cell wall. Molecular formula: C50H82N8O16. Mole weight: 1051.23.
Caspofungin Impurity E
Caspofungin Impurity E is an impurity of Caspofungin, an antifungal agent in echinocandin class. Caspofungi is effective against infections with Aspergillus and Candida and functions via inhibiting β(1,3)-D-Glucan of the fungal cell wall. Molecular formula: C50H82N8O16. Mole weight: 1051.23.
Deoxy micafungin
Deoxy micafungin is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Synonyms: Deoxy Micafungin Impurity; Sodium 5-((1S,2S)-2-((2R,6S,9S,12R,14aS,15S,16S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,12,15-trihydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sulfate. Grade: 90%. CAS No. 1392514-06-5. Molecular formula: C56H70N9NaO22S. Mole weight: 1276.26.
Deoxymulundocandin
Deoxymulundocandin is an echinocandin antifungal agent isolated from Aspergillus sydowii. Synonyms: L-Proline, (4R,5R)-4,5-dihydroxy-N2-(12-methyl-1-oxotetradecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, cyclic (6-1)-peptide, (2alpha,3beta,4beta)-. Grade: 90%. CAS No. 138626-63-8. Molecular formula: C48H77N7O15. Mole weight: 992.16.
Desmethyl Micafungin Sodium salt
Desmethyl Micafungin Sodium salt is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Synonyms: 5-((1S,2S)-2-((2R,9S,11R,12R,14aS,15S,20S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate, sodium salt; Micafungin Impurity B. CAS No. 1392514-03-2. Molecular formula: C55H68N9NaO23S. Mole weight: 1178.24.
FR 901379
FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6→1)-Peptide; 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine Cyclic Peptide Deriv. Grade: ≥90%. CAS No. 144371-88-0. Molecular formula: C51H82N8O21S. Mole weight: 1175.30.
Micafungin sodium
Micafungin sodium a cyclic hexapeptide echinocandin lipopeptide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FK463; FK 463; FK-463; Micafungin sodium. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 208538-73-2. Molecular formula: C56H70N9NaO23S. Mole weight: 1292.27. Purity: >98%. IUPACName: sodium 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sulfate. Canonical SMILES: [Na+].CCCCCOc1ccc(cc1)c2onc(c2)c3ccc(cc3)C(=O)N[C@H]4C[C@@H](O)[C@@H](O)NC(=O)[C@@H]5[C@@H](O)[C@@H](C)CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@@H](O)CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)[C@H](O)[C@@H](O)c7ccc(O)c(OS(=O)(=O)[O-])c7)[C@H](O)CC(=O)N. Product ID: ACM208538732. Alfa Chemistry ISO 9001:2015 Certified.
Papulacandin A
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-(1-oxo-2,4-decadienyl)-β-D-galactopyranosyl]-α-D-glucopyranose3-(7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[(7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraenyl)oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-(2,4-decadienoate). CAS No. 61036-46-2. Molecular formula: C47H66O16. Mole weight: 887.02.
Papulacandin B
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. The mechanism of B is to inhibit the synthesis of glucan in yeast cell wall. Synonyms: alpha-D-Glucopyranose, 1,16-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4,6-decatrienyl)-beta-D-galactopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-2,4,8,10-hexadecatetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[[(2E,4E,8E,10E)-7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraen-1-yl]oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-[(2E,4Z,6E)-8-hydroxy-2,4,6-decatrienoate]. CAS No. 61032-80-2. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin C
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: (1S,3'R,4'R,5'R,6'R)-3',5,7-trihydroxy-5'-({6-O-[(2E,4E,6E)-8-hydroxydeca-2,4,6-trienoyl]-beta-D-galactopyranosyl}oxy)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate; 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-[(2E,4E,6E)-1-oxo-8-hydroxy-2,4,6-decatrienyl]-beta-D-galactopyranosyl]-alpha-D-glucopyranose 3-[(2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate]. CAS No. 61036-48-4. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin D
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: (+)-papulacandin D; (1S,3'R,4'S,5'R,6'R)-3',5,5',7-tetrahydroxy-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate. CAS No. 61036-49-5. Molecular formula: C31H42O10. Mole weight: 574.66.
Pneumocandin B0
Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis , is a synthetic intermediate of Cancidas [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: L-688786. CAS No. 135575-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17578.
Rezafungin
Rezafungin, a next-generation, broad-spectrum and long-lasting echinocandin, has potent antifungal activity against Candida spp., Aspergillus spp. and Pneumocystis spp. Synonyms: Biafungin; CD101; SP-3025; 2-{[(2R,6S,9S,11R,12S,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-({[4''-(pentyloxy)-1,1':4',1''-terphenyl-4-yl]carbonyl}amino)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl]oxy}-N,N,N-trimethylethanaminium. Grade: ≥95%. CAS No. 1396640-59-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.39.
Rezafungin acetate
Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp. , Aspergillus spp. , and Pneumocystis spp. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Biafungin acetate; CD101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108009A.
trans-4-Hydroxy-L-proline, ≥99%
Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids. Uses: Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes. Additional or Alternative Names: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp. Product Category: Amino Acids. CAS No. 51-35-4. Mole weight: 131.13. Canonical SMILES: O[C@H]1CN[C@@H](C1)C(O)=O. ECNumber: 200-091-9. Product ID: ACM51354-4. Alfa Chemistry ISO 9001:2015 Certified.
Anidulafungin Impurity 1
Anidulafungin Impurity 1 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C58H73N7O17. Mole weight: 1140.25.
Anidulafungin Impurity 2
Anidulafungin Impurity 2 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C5H12N2O4. Mole weight: 164.16.
Anidulafungin Impurity 4
Anidulafungin Impurity 4 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. CAS No. 54615-51-9. Molecular formula: C6H11NO3. Mole weight: 145.16.
Anidulafungin Impurity 5
Anidulafungin Impurity 5 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C25H23NO7. Mole weight: 449.46.
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