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Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogenesis through inhibiting JNK and p38 MAPK pathways in AMD, glaucoma, DR, and RVO animal models. Group: Biochemicals. Alternative Names: 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one; 1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one; methyl phenylpyrazolone; NCI-C 03952; NSC 12;NSC 26139; NSC 2629; Norantipyrine; Norphenazone; Radicut; USP Antipyrine Related Compound A. Grades: Purified. CAS No. 89-25-8. Pack Sizes: 10g, 25g, 50g. Molecular Formula: C??H??N?O, Molecular Weight: 174.2. US Biological Life Sciences.
Worldwide
Edaravone
Edaravone is a novel free radical scavenger, which was first marketed in Japan in April 2001 and is mainly used in the treatment of ischemic stroke. CAS No. 89-25-8. Product ID: PAP-0070. Molecular formula: C10H10N2O. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Edaravone; PAP-0070; Cardiovascular; C10H10N2O; 89-25-8. Appearance: Crystalline Powder. Color: Yellow to beige. Physical State: Crystalline Powder. Solubility: 3.30g/l. Storage: 2-8°C. Applications: Edala is considered a brain protectant (free radical scavenger). It is mainly used to treat the acute attack of cerebral infarction and improve the neurological symptoms, activities of daily living and functional disorders caused by acute cerebral infarction. Boiling Point: 287 °C265 mm Hg(lit.). Melting Point: 126-128 °C(lit.). Density: 1,12 g/cm3.
Edaravone
Edaravone is a strong novel free radical scavenger, and inhibits MMP -9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-186. CAS No. 89-25-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-B0099.
Edaravone-d5
Edaravone-d 5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MCI-186-d5. CAS No. 1228765-67-0. Pack Sizes: 1 mg. Product ID: HY-B0099S.
Edaravone D5
2H Labeled Compounds. Alternative Names: 5-methyl-2-(phenyl-d5)-2,4-dihydro-3H-pyrazol-3-one. CAS No. 1228765-67-0. Mole weight: 179.23. Purity: >95%. Catalog: ACM1228765670.
Edaravone Impurity 1
Edaravone Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,3'-dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazole]-5,5'-diol. CAS No. 177415-76-8. Molecular Formula: C20H18N4O2. Mole Weight: 346.38. Catalog: APB177415768.
Edaravone impurity 10
Edaravone impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 2-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-sulfonatopropanoate. Molecular Formula: C13H12N2Na2O6S. Mole Weight: 370.29. Catalog: APB05487.
Edaravone Impurity 16
Edaravone Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole 2-oxide. Molecular Formula: C10H10N2O2. Mole Weight: 190.2. Catalog: APB05484.
Edaravone Impurity 17
Edaravone Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-hydroxy-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one. Molecular Formula: C10H10N2O2. Mole Weight: 190.2. Catalog: APB05483.
Edaravone Impurity 18
Edaravone Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-3-oxobutane-2-sulfonic acid. Molecular Formula: C14H16N2O5S. Mole Weight: 324.35. Catalog: APB05485.
Edaravone Impurity 19
Edaravone Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-oxo-N-phenylbutanehydrazide. Molecular Formula: C10H12N2O2. Mole Weight: 192.21. Catalog: APB05482.
Edaravone Impurity 2
Edaravone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5,5''-dihydroxy-3,3'',5'-trimethyl-1,1'',2'-triphenyl-1H,1''H-[4,4':4',4''-terpyrazol]-3'(2'H)-one. CAS No. 124009-63-8. Molecular Formula: C30H26N6O3. Mole Weight: 518.57. Catalog: APB124009638.
Edaravone Impurity 2
Edaravone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H14N2O6S. Mole Weight: 326.32. Catalog: APB11686.
Edaravone Impurity 3
Edaravone Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-5-methyl-1-phenyl-1H-pyrazole. CAS No. 300543-31-1. Molecular Formula: C12H14N2O. Mole Weight: 202.25. Catalog: APB300543311.
Edaravone Impurity 4
Edaravone Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-ethoxy-3-methyl-1-phenyl-1H-pyrazole. CAS No. 1016-41-7. Molecular Formula: C12H14N2O. Mole Weight: 202.25. Catalog: APB1016417.
Edaravone Impurity 4
Edaravone Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H16N2O4S. Mole Weight: 296.34. Catalog: APB11687.
Edaravone Impurity 5
Edaravone Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-ethyl 3-acetoxybut-2-enoate. CAS No. 29214-62-8. Molecular Formula: C8H12O4. Mole Weight: 172.18. Catalog: APB29214628.
Edaravone Impurity 5
Edaravone Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C10H10N2O2. Mole Weight: 190.2. Catalog: APB11688.
Edaravone Impurity 6
Edaravone Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H16N4O3. Mole Weight: 360.37. Catalog: APB11689.
Edaravone impurity B
Edaravone impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,3'',5'-trimethyl-1,1'',2'-triphenyl-1H,1''H-[4,4':4',4''-terpyrazole]-3',5,5''(2'H,4H,4''H)-trione. CAS No. 68195-63-1. Molecular Formula: C30H26N6O3. Mole Weight: 518.57. Catalog: APB68195631.
Edaravone impurity DEE
Edaravone impurity DEE. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5,5'-Dimethyl-1-oxy-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione. Molecular Formula: C20H16N4O3. Mole Weight: 360.37. Catalog: APB05486.
Edaravone impurity DO
Edaravone impurity DO. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-Methyl-2-phenyl-2H-pyrazole-3,4-diol. CAS No. 5393-61-3. Molecular Formula: C10H10N2O2. Mole Weight: 190.2. Catalog: APB5393613.
Edaravone impurity EPH
Edaravone impurity EPH. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(Phenyl-hydrazono)-butyric acid ethyl ester. CAS No. 6078-46-2. Molecular Formula: C12H16N2O2. Mole Weight: 220.27. Catalog: APB6078462.
Edaravone impurity HPO
Edaravone impurity HPO. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-hydroxy-3-methyl-1-phenyl-1H-pyrazole 2-oxide. CAS No. 152494-76-3. Molecular Formula: C10H10N2O2. Mole Weight: 190.20. Catalog: APB152494763.
Edaravone Impurity IV is an impurity of Edaravone, which is a potent free radical scavenger used to treat stroke and amyotrophic lateral sclerosis (ALS). Synonyms: Bispyrazolone; 2,2',4,4'-Tetrahydro-5,5'-dimethyl-2,2'-diphenyl-[4,4'-Bi-3H-pyrazole]-3,3'-dione; 3,3'-Dimethyl-1,1'-diphenyl-[4,4'-bi-2-pyrazoline]-5,5'-dione; 4,4'-Bis(1-phenyl-3-methyl-5-pyrazolone); NSC 37393; NSC 401001; Edaravone dimer; 3-Methyl-4-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-1-phenyl-4,5-dihydro-1H-pyrazol-5-one. Grades: ≥95%. CAS No. 7477-67-0. Molecular formula: C20H18N4O2. Mole weight: 346.38.
Edaravone impurity P1
Edaravone impurity P1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoic acid. CAS No. 1357477-99-6. Molecular Formula: C13H14N2O6S. Mole Weight: 326.33. Catalog: APB1357477996.
Edaravone impurity P3
Edaravone impurity P3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic acid. CAS No. 1323485-71-7. Molecular Formula: C13H16N2O4S. Mole Weight: 296.34. Catalog: APB1323485717.
Edaravone impurity P3
Edaravone Impurity. Synonyms: Edaravone Impurity VI. Grades: > 95%. CAS No. 1323485-71-7. Molecular formula: C13H16N2O4S. Mole weight: 296.35.
Edaravone Impurity P4
Edaravone Impurity P4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-hydroxy-2-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)propane-2-sulfonic acid. CAS No. 1242471-40-4. Molecular Formula: C13H16N2O5S. Mole Weight: 312.34. Catalog: APB1242471404.
Edaravone impurity PBH
Edaravone impurity PBH. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-Oxo-butyric acid N'-phenyl-hydrazide. CAS No. 710307-89-4. Molecular Formula: C10H12N2O2. Mole Weight: 192.21. Catalog: APB710307894.
Edaravone Impurity V
An impurity of Edaravone, a medication for the recovery from stroke. Synonyms: 4,4-Bis(1-phenyl-3-methyl-5-oxo-3-pyrazoline-4-yl)-1-phenyl-3-methyl-1H-pyrazole-5(4H)-one. Grades: >95%. CAS No. 124009-63-8. Molecular formula: C30H26N6O3. Mole weight: 518.577.
Edaravone (Standard)
Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. CAS No. 89-25-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0099R.
Edaravone Trimer
Edaravone Trimer is an impurity of Edaravone. Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibits apoptosis, and blocks nonenzymatic peroxidation and lipoxygenase activity. Synonyms: 5,?5',?5''-trimethyl-2,?2',?2''-triphenyl-[4,?4':4',?4''-Ter-4H-pyrazole]?-3,?3',?3''(2H,?2'H,?2''H)?-trione; 4,4-bis(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-3-methyl-1-phenyl-2-pyrazol in-5-one; 2-Phenyl-5-methyl-4,4-bis(2-phenyl-3-oxo-5-methyl-3,4-dihydro-2H-pyrazole-4-yl)-3,4-dihydro-2H-pyrazole-3-one. CAS No. 68195-63-1. Molecular formula: C30H26N6O3. Mole weight: 518.577.
1-Phenyl-3-ethoxy-5-methyl-1H-pyrazole
An impurity of Edaravone, a medication for the recovery from stroke. Synonyms: 3-ethoxy-5-methyl-1-phenyl-1H-pyrazole; 1H-Pyrazole, 3-ethoxy-5-methyl-1-phenyl-. CAS No. 300543-31-1. Molecular formula: C12H14N2O. Mole weight: 202.257.
2,4-Dihydro-5-methyl-2-(4-methylphenyl)-3H-Pyrazol-3-one is used as an antioxidant. Edaravone (E335000) derivative. Group: Biochemicals. Alternative Names: 1-(p-Tolyl)-3-methylpyrazolone-5; 1-p-Tolyl-3-methyl-5-pyrazolone; 2,4-Dihydro-5-methyl-2-(4-methylphenyl)-3H-pyrazol-3-one; 3-Methyl-1-(4-methylphenyl)-2-pyrazolin-5-one; 3-Methyl-1-(4-methylphenyl)-5-pyrazolone; 3-Methyl-1-(p-tolyl)-2-pyrazolin-5-one; 3-Methyl-1-p-tolyl-5-pyrazolone. Grades: Highly Purified. CAS No. 86-92-0. Pack Sizes: 50g. US Biological Life Sciences.
An impurity of Edaravone, a medication for the recovery from stroke. Synonyms: 3,3'-dimethyl-1,1'-diphenyl-1h,1'h-4,4'-bipyrazole-5,5'-diol. CAS No. 177415-76-8. Molecular formula: C20H18N4O2. Mole weight: 346.39.