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Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a K i of 2.93 nM and exhibits an IC 95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DMP 266; EFV; L-743726. CAS No. 154598-52-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10572.
Efavirenz
Heterocyclic Organic Compound. CAS No. 5278-11-8. Catalog: ACM1234103.
Efavirenz 1-Desamine
Efavirenz 1-Desamine is an analog of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Alternative Names: 7-Chloro-1- (cyclopropylethynyl) -1- (trifluoromethyl) isochroman-3-one. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C15H10ClF3O2. US Biological Life Sciences.
Worldwide
Efavirenz Benzoylaminoalcohol Impurity
An impurity arising in the synthesis of Efavirenz. Synonyms: rac N-[4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl]phenyl]-4-methoxybenzamide. Grades: > 95%. CAS No. 1189491-03-9. Molecular formula: C21H17ClF3NO3. Mole weight: 423.81.
Efavirenz Impurity 1
Efavirenz Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. CAS No. 154801-74-8. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB154801748.
Efavirenz Impurity 10
Efavirenz Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-methyl (4-chloro-2-(4-cyclopropyl-1,1,1-trifluoro-2-hydroxybut-3-yn-2-yl)phenyl)carbamate. CAS No. 211563-40-5. Molecular Formula: C15H13ClF3NO3. Mole Weight: 347.72. Catalog: APB211563405.
Efavirenz Impurity 11
Efavirenz Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R,E)-6-chloro-4-(2-cyclopropylvinyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H11ClF3NO2. Mole Weight: 317.69. Catalog: APB06088.
Efavirenz Impurity 12
Efavirenz Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-ethyl (4-chloro-2-(4-cyclopropyl-2-((ethoxycarbonyl)oxy)-1,1,1-trifluorobut-3-yn-2-yl)phenyl)carbamate. CAS No. 2733280-20-9. Molecular Formula: C19H19ClF3NO5. Mole Weight: 433.81. Catalog: APB2733280209.
Efavirenz Impurity 13
Efavirenz Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4S)-6-chloro-4-(cyclopropylethynyl)-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2,4-dihydro-1H-benzo[d][1,3]oxazine. CAS No. 209414-26-6. Molecular Formula: C21H17ClF3NO2. Mole Weight: 407.81. Catalog: APB209414266.
Efavirenz Impurity 14
Efavirenz Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(5-chloro-2-((4-methoxybenzyl)amino)phenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol. CAS No. 173676-60-3. Molecular Formula: C21H19ClF3NO2. Mole Weight: 409.83. Catalog: APB173676603.
Efavirenz Impurity 15
Efavirenz Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-chloro-4-(cyclopropylethynyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. CAS No. 174819-21-7. Molecular Formula: C22H17ClF3NO3. Mole Weight: 435.82. Catalog: APB174819217.
Efavirenz Impurity 16
Efavirenz Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-chloro-4-(3-methylbut-3-en-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB06087.
Efavirenz Impurity 17
Efavirenz Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-chloro-4-(pent-3-en-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. CAS No. 2125704-30-3. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB2125704303.
Efavirenz Impurity 18
Efavirenz Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloro-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. CAS No. 1627575-36-3. Molecular Formula: C14H11ClF3NO2. Mole Weight: 317.69. Catalog: APB1627575363.
Efavirenz Impurity 19
Efavirenz Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 5-chloro-2-(cyclobut-1-en-1-yl)-3-(trifluoromethyl)-1H-indole-1-carboxylate. CAS No. 2177283-35-9. Molecular Formula: C16H13ClF3NO2. Mole Weight: 343.73. Catalog: APB2177283359.
Efavirenz Impurity 2
Efavirenz Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloro-4-(3-methylbut-3-en-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB06093.
Efavirenz Impurity 20
Efavirenz Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,3-bis(4-chloro-2-((S)-4-cyclopropyl-1,1,1-trifluoro-2-hydroxybut-3-yn-2-yl)phenyl)urea. Molecular Formula: C27H20Cl2F6N2O3. Mole Weight: 605.36. Catalog: APB06086.
Efavirenz Impurity 3
Efavirenz Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloro-4-(pent-3-en-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB06094.
Efavirenz Impurity 4
Efavirenz Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-6-chloro-4-(pent-3-en-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.67. Catalog: APB06092.
Efavirenz Impurity 6
Efavirenz Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloro-4-(5-chloropent-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one. Molecular Formula: C14H10Cl2F3NO2. Mole Weight: 352.14. Catalog: APB06089.
Efavirenz impurity (6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) is an impurity of Efavirenz, a medication used to treat HIV/AIDS. Grades: > 95%. CAS No. 1217623-65-8. Molecular formula: C15H11ClF3NO2. Mole weight: 329.71.
Heterocyclic Organic Compound. CAS No. 5278-11-19. Catalog: ACM1234114.
Efavirenz Related Compound A
Cas No. 209414-27-7.
Efavirenz Related Compound B
Efavirenz impurity. Synonyms: (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one; USP Efavirenz Related Compound B. Grades: > 95%. CAS No. 440124-96-9. Molecular formula: C14H11ClF3NO2. Mole weight: 317.69.
Efavirenz Related Compound C
An impurity of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent. Synonyms: 2-Cyclopropyl-6-chloro-4-(trifluoromethyl)quinoline, USP Efavirenz Related Compound C. Grades: > 95%. CAS No. 391860-73-4. Molecular formula: C13H9ClF3N. Mole weight: 271.67.
Efavirenz (Sustiva, MDP-266, L-743726)
A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266; L 743726; Stocrin; Sustiva. Grades: Highly Purified. CAS No. 154598-52-4. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C14H9ClF3NO2, Molecular Weight: 315.67. US Biological Life Sciences.
Worldwide
2-Deoxo-3-desoxy Efavirenz
2-Deoxo-3-desoxy Efavirenz is a derivative of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C15H13ClF3N, Molecular Weight: 299.72. US Biological Life Sciences.
Worldwide
8-Hydroxy Efavirenz
8-Hydroxy Efavirenz is a metabolite of Efavirenz. Synonyms: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz. Grades: > 95%. CAS No. 205754-33-2. Molecular formula: C14H9ClF3NO3. Mole weight: 331.67.
(E)-Dihydro Efavirenz is an impurity of the nonnucleoside HIV-1 reverse transcriptase inhibitor Efavirenz. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one; SR 695. Grades: Highly Purified. CAS No. 440124-96-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(E)-Dihydro Efavirenz
(E)-Dihydro Efavirenz. Uses: For analytical and research use. Group: Impurity standards. CAS No. 440124-96-9. Pack Sizes: 5MG. IUPAC Name: (4S)-6-chloro-4-[(E)-2-cyclopropylethenyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Molecular Formula: C14H11ClF3NO2. Mole Weight: 317.69. Catalog: APS440124969. SMILES: FC (F) (F)[C@]1 (OC (=O)Nc2ccc (Cl)cc12)\C=C\C3CC3. Format: Neat. Shipping: Room Temperature.
ent-Efavirenz
A nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Alternative Names: (4R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; L 743725. Grades: Highly Purified. CAS No. 154801-74-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
rac 7-Hydroxy Efavirenz
A metabolite of Efavirenz (minor). Group: Biochemicals. Alternative Names: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 205754-50-3. Pack Sizes: 500ug, 1mg, 2mg. US Biological Life Sciences.
Worldwide
rac 7-Hydroxy Efavirenz-d4 (Major)
An isotope labeled metabolite of Efavirenz (minor). A representative lot was 84% d4, 12% d5, 2% d3 and 1% d6. Group: Biochemicals. Alternative Names: 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac 8,14-Dihydroxy Efavirenz
A metabolite of Efavirenz (secondary metabolism. Group: Biochemicals. Alternative Names: 6-Chloro-1, 4-dihydro-8-hydroxy-4-[ (1-hydroxycyclopropyl) ethynyl]-4- (trifluoromethyl) -2H-3, 1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 1189909-96-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac 8,14-Dihydroxy Efavirenz-d4
A labeled metabolite of Efavirenz (secondary metabolism. Group: Biochemicals. Alternative Names: 6-Chloro-1,4-dihydro-8-hydroxy-4-[(1-hydroxycyclopropyl-d4)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 1189859-26-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac 8-Hydroxy Efavirenz
A metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac 8-Hydroxy Efavirenz
A metabolite of Efavirenz , a nonnucleoside HIV-1 reverse transcriptase inhibitor. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 205754-32-1. Molecular formula: C14H9ClF3NO3. Mole weight: 331.68.
rac 8-Hydroxy Efavirenz-d4
A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
rac Efavirenz
rac Efavirenz is a mixture of both enantiomers for Efavirenz. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 177530-93-7. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67.
rac Efavirenz-d4
Labelled Efavirenz (E42500). A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-4-(2-cyclopropyl-d4-ethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266-d4; L 743726-d4; Stocrin-d4; Sustiva-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Efavirenz-d5 (major)
Labeled Efavirenz. A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-4-(2-cyclopropyl-d5-ethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266-d5; L 743726-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
1- (2- ( (tert-Butyldimethylsilyl) oxy) -5-chlorophenyl) -2, 2, 2-trifluoroethanone is an intermediate in the synthesis of Efavirenz De(1-amino-3-oxo)-1-oxo-3-amine, which is an analog of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C14H18ClF3O2Si. US Biological Life Sciences.
Worldwide
1,3-Bis(methoxymethyl)-2-nitrobenzene
1,3-Bis(methoxymethyl)-2-nitrobenzene is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H13NO4. US Biological Life Sciences.
Worldwide
(1Z)-Rilpivirine
(1Z)-Rilpivirine is a stereoisomer of Rilpivirine (R509800) which is a non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. Group: Biochemicals. Grades: Highly Purified. CAS No. 500287-94-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H18N6, Molecular Weight: 366.42. US Biological Life Sciences.
2- (2- (2- ( (tert-Butyldimethylsilyl) oxy) ethyl) -5-chlorophenyl) -4-cyclopropyl-1, 1, 1-trifluorobut-3-yn-2-ol is an analog of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H28ClF3O2Si. US Biological Life Sciences.
Worldwide
2,2,2-Trifluoroethanol-1,1-d2
Isotope labelled 2,2,2-Trifluoroethanol (T790175), is used in the synthesis of competitive inhibitors for phospholipase A2. Used in the preparation of a key Efavirenz (E425000) intermediate, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 132248-58-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C2HD2F3O, Molecular Weight: 102.05. US Biological Life Sciences.
2-(5-Chloro-2-(2-hydroxyethyl)phenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol is an analog of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H14ClF3O2. US Biological Life Sciences.
2- (5-Chloro-2- (4-methoxybenzamido) phenyl) -4-cyclopropyl-1, 1, 1-trifluorobut-3-yn-2-yl 4-Methoxybenzoate is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2, 6-Bis (methoxymethyl)aniline
2, 6-Bis (methoxymethyl)aniline is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H15NO2. US Biological Life Sciences.
2-Amino-5-chloro-α - (cyclopropylethynyl) -α - (trifluoromethyl) benzenemethanol-d4 is an isotope labelled impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H7D4ClF3NO. US Biological Life Sciences.
Worldwide
2-Hydroxymethyl Rilpivirine
2-Hydroxymethyl Rilpivirine is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1798429-64-7. Pack Sizes: 500ug, 5mg. Molecular Formula: C22H18N6O. US Biological Life Sciences.
Worldwide
2-Nitro-1,3-benzenedimethanol
2-Nitro-1,3-benzenedimethanol is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16578-60-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C8H9NO4. US Biological Life Sciences.
(2S, 3R, 4R, 5S) -6- ( (2- ( (2- ( (4-Cyanophenyl) amino) pyrimidin-4-yl) amino) -5- ( (E) -2-cyanovinyl) -3- (hydroxymethyl) benzyl) oxy) -3, 4, 5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is a metabolite of Rilpivirine (R509800), which is a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine is an anti-HIV agent that seems to be well tolerated with less CNS disturbance than Efavirenz and has non-teratogenic potential. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C28H26N6O8, Molecular Weight: 574.54. US Biological Life Sciences.
(2S, 3R, 4R, 5S) -6- ( (2- ( (2- ( (4-Cyanophenyl) amino) pyrimidin-4-yl) amino) -5- ( (E) -2-cyanovinyl) -3-methylbenzyl) oxy) -3, 4, 5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is a metabolite of Rilpivirine (R509800), which is a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine is an anti-HIV agent that seems to be well tolerated with less CNS disturbance than Efavirenz and has non-teratogenic potential. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C28H26N6O7, Molecular Weight: 558.54. US Biological Life Sciences.
Worldwide
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