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| Product | Description | |
|---|---|---|
| EGA | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| EGA | EGA is an inhibitor of endosomal trafficking. EGA is a small molecule that blocks the entry of anthrax lethal toxin by inhibiting trafficking pathways in acidified endosomes, without affecting endosome pH. It also blocks trafficking of other toxins, except ricin. Synonyms: 2-[(4-bromophenyl)methylene]-N-(2,6-dimethylphenyl)-hydrazinecarboxamide. Grades: ≥98%. CAS No. 415687-81-9. Molecular formula: C16H16BrN3O. Mole weight: 346.2. |  |
| EGA | EGA is an inhibitor that selectively targets the endosomal trafficking pathways. EGA targets the proteins involved in the endosomal trafficking pathways through which multiple toxins and viruses enter cells. EGA exerts its activity by inhibiting the trafficking from early endosomes to late endosomes, blocking the entry of multiple acid-dependent bacterial toxins and viruses into mammalian cells and delaying the lysosomal targeting and degradation of EGFR [1]. X. Uses: Scientific research. Group: Signaling pathways. CAS No. 415687-81-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125168. |  |
| Egalognastat | Egalognastat is a specific and orally active O-GlcNAcase (OGA) enzyme inhibitor with IC 50 value of 10.2 nM. Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASN90. CAS No. 1884154-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156586. | |
| Eganelisib | Eganelisib (IPI549) is a potent and selective PI3Kγ inhibitor with an IC 50 of 16 nM. Eganelisib shows >100-fold selectivity over other lipid and protein kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-549. CAS No. 1693758-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100716. | |
| 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole (Triclabendazole) | Triclabendazole is a member of the benzimidazole family of anthelmintics. It is effective against F. hepatica helminths that cause fascioliasis, reducing secreted protease enzyme activities that are critical for the invasion, migration, nutrition, and survival of the parasite.1 In yeast and mammalian cells, triclabendazole was shown to inhibit adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway and to prevent apoptosis induced by the Parkinsons disease-related protein α-synuclein, demonstrating a protective role during various cellular stresses.2,3. Group: Biochemicals. Alternative Names: 5-Chloro-6- (2, 3-dichlorophenoxy) -2- methyl thiobenzimidazole; CGA-89317, egaten; Fasinex; Triclabendazole. Grades: Highly Purified. CAS No. 68786-66-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C14H9Cl3N2OS, Molecular Weight: 359.66. US Biological Life Sciences. |  Worldwide |
| L-Glutamate Decarboxylase (Crude Enzyme) | Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO 2. In mammals, GAD exists in two isoforms encoded by two different genes - GAD1 and GAD2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD1 and GAD2 are expressed in the brain where GABA is used as a neurotransmitter, GAD2 is also expressed in the pancreas. At least two more forms, GAD25 and GAD44 (embryonic; EGAD) are described in the developing brain. They are coded by the alternative transcripts of GAD1, I-80 and I-86: GAD25 is coded by both, GAD44 - only by I-80.This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Medicine; synthesis; diagnostics; food industry. Group: Enzymes. Synonyms: L-glutamic acid. Enzyme Commission Number: EC 4.1.1.15. CAS No. 9024-58-2. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. L-glutamic acid decarboxylase; L-glutamic decarboxylase; cysteic acid decarboxylase; L-glutamate α-decarboxylase; aspartate 1-decarboxylase; aspartic α-decarboxylase; L-aspartate-α-decarboxylase; γ-glutamate decarboxylase; L-glutamate 1-carboxy-lyase. Pack: 100ml. Cat No: NATE-1846. |  |
| ORANGE I | ORANGE I. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Naphthol orange, Tropaeolin G, Tropaeolin 1, Orange I, Orange S, Aizen Orange I, Orange IM, Acid Orange I, Eniacid Orange I, Java Orange I, Egacid Orange GG, Acid phosphine CL, Certiqual Orange I, Hispacid Orange 1, Neklacid Orange 1, Tertracid Orange I, FDC Orange I, Acid Orange 20, Elgacid Orange 2G, Naphthalene Orange I. Product Category: Acid Dyes. CAS No. 523-44-4. Molecular formula: C16H11N2NaO4S. Mole weight: 350.32. Purity: Dye conten >95%. IUPACName: sodium 4-[2-(4-oxonaphthalen-1-ylidene)hydrazinyl]benzenesulfonic acid. Product ID: ACM523444. Alfa Chemistry ISO 9001:2015 Certified. Categories: Orange Is the New Black. |  |
| THIP | THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors ( eGABARs ) agonist (with blood-brain barrier permeability), shows an EC 50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA -mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gaboxadol. CAS No. 64603-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10232. | |
| Triclabendazole | Triclabendazole is a benzimidazole, and it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis. It is a new type of imidazole anthelmintic. It is effective for Fasciola hepatica in ruminants such as cattle, sheep, goats, and Fasciola hepatica, Fasciola deer, Fasciola hepatica, Fasciola hepatica, etc. Synonyms: 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthiobenzimidazole; CGA-89317, Egaten; Fasinex. Grades: >98%. CAS No. 68786-66-3. Molecular formula: C14H9Cl3N2OS. Mole weight: 359.66. | |
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