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| Product | Description | |
|---|---|---|
| Eicosanoic acid | Liquid; OtherSolid;Solid. Group: Solubility enhancing reagents. Alternative Names: Arachidic acid. CAS No. 506-30-9. Product ID: icosanoic acid. Molecular formula: 312.53. Mole weight: C20H40O2. CCCCCCCCCCCCCCCCCCCC(=O)O. InChI= 1S / C20H40O2 / c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15- 16-17-18-19-20 (21) 22 / h2-19H2, 1H3, (H, 21, 22). VKOBVWXKNCXXDE-UHFFFAOYSA-N. 99%+. |  |
| 2-Hexadecyleicosanoic acid | 2-Hexadecyleicosanoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-hexadecylicosanoic acid;Eicosanoic acid, 2-hexadecyl-;2-Hexadecyleicosanoic acid;Einecs 260-078-9. Product Category: Heterocyclic Organic Compound. CAS No. 56253-91-9. Molecular formula: C36H72O2. Mole weight: 536.95568. Product ID: ACM56253919. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Arachidic acid | Arachidonic acid (Icosanoic acid), an orally active long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant saturated fatty acids present in human tissue. Moreover, Arachidonic acid is an important mediator of inflammation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Eicosanoic acid. CAS No. 506-30-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W004260. |  |
| Arachidic acid (Standard) | Arachidic acid (Standard) is the analytical standard of Arachidic acid. This product is intended for research and analytical applications. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Eicosanoic acid (Standard). CAS No. 506-30-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W004260R. | |
| Ethyl eicosanoate | Ethyl eicosanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosanoic acid ethyl ester. Product Category: Fatty Acids and Ester Homologs. Appearance: Solid. CAS No. 18281-05-5. Molecular formula: C22H44O2. Mole weight: 340.58. Purity: 99%+. Product ID: ACM18281055-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ethyl arachidate. | |
| Methyl arachidate | Methyl arachidate is a natural compound which can be isolated from Lepidium meyenii, Begonia heracleifolia, etc. Synonyms: Methyl eicosanoate; Arachidic acid methyl ester; Eicosanoic acid, methyl ester. Grades: 98%. CAS No. 1120-28-1. Molecular formula: C21H42O2. Mole weight: 326.56. |  |
| Methyl eicosanoate | Methyl eicosanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosanoic acid methyl ester. Product Category: Heterocyclic Organic CompoundFatty Acids and Ester Homologs. Appearance: Solid. CAS No. 1120-28-1. Molecular formula: C21H42O2. Mole weight: 326.57. Purity: 99%+. Product ID: ACM1120281. Alfa Chemistry ISO 9001:2015 Certified. Categories: Methyl arachidate. | |
| (±)17(18)-EpETE | The epoxygenase pathway is one of the three major branches of eicosanoid biosynthesis. Synonyms: (±)17,18-EEQ; (±)17,18-epoxy Eicosatetraenoic Acid; (5Z,8Z,11Z,14Z)-16-(3-ethyloxiran-2-yl)hexadeca-5,8,11,14-tetraenoic acid. Grades: ≥90%. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| Arachidonic acid | Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Synonyms: Arachidonate. Grades: 98 %. CAS No. 506-32-1. Molecular formula: C20H32O2. Mole weight: 304.47. | |
| Arachidonic acid-[13C20] | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Grades: > 98%. Molecular formula: [13C]20H32O2. Mole weight: 324.32. | |
| CAY10590 | Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, liberating arachidonic acid for subsequent eicosanoid synthesis. There are three primary types of PLA2 exist: secretory (sPLA2), calcium-dependent cytosolic (cPLA2), and calcium-independent cytosolic (iPLA2). CAY10590 is a selective and potent inhibitor of sPLA2. It exhibits 95% inhibition (XI(50) = 0.003) of sPLA2 at 0.091 mole fraction without affecting the activities of cPLA2 or iPLA2. Synonyms: CAY 10590; CAY-10590. Grades: ≥98%. CAS No. 1101136-50-8. Molecular formula: C21H33NO3. Mole weight: 347.5. | |
| Cyclooxygenase 1 from Human, Recombinant | COX-1 catalyzes the conversion of arachidonic acid to prostaglandin H2 (the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins). It is involved in the homeostatic role of eicosanoids and constitutively almost all animal tissues. Has an apparent KM of 8.3 μM for arachidonic acid. Group: Enzymes. Synonyms: COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. COX-1. Mole weight: ~70 kDa. Activity: >20,000 units/mg. Stability: > 6 months. Storage: -80°C (as supplied); avoid freeze/thaw cycles by aliquoting protein. Form: 80 mM Tris, pH 8.0, containing 0.1% polysorbate 20, 300 uM DDC, and 10% glycerol. Source: Sf21 cells. Species: Human. COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: NATE-1237. |  |
| Dihomo-γ-Linolenic acid methyl ester | Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 21061-10-9. Pack Sizes: 5 mg (312 mM * 50 μL in Ethanol); 10 mg (312 mM * 100 μL in Ethanol). Product ID: HY-116015. | |
| KT109 | KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-β (DAGLβ) with an IC 50 of 42 nM. KT109 has ~60-fold selectivity for DAGLβ over DAGL&alpha. KT109 shows inhibitory activity against PLA2G7 (IC 50 =1 μM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-arachidonoylglycerol (2-AG), arachidonic acid and eicosanoids in mouse peritoneal macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402612-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18540. | |
| Native Crotalus Phospholipase A2 | Phospholipases A2 (PLA2s) EC 3.1.1.4 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Upon downstream modification by cyclooxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as anti-inflammatory and inflammatory mediators. Phospholipase a2 is a member of the class of heat-stable, calcium-dependent enzymes catalyzing the hydrolysis of the 2-acyl bond of 3-n-phosphoglycerides. a chromatographically purified, dialyzed, lyophilized powder. Group: Enzymes. Synonyms: EC 3.1.1.4; Phospholipases A2; PLA2s. Enzyme Commission Number: EC 3.1.1.4. CAS No. 9001-86-9. Purity: chromatographically purified, dialyzed. PLA2. Mole weight: 30 kDa (Wells 1969). Activity: > 200 units per mg dry weight. Stability: The enzyme is stable at 90°C and pH 3.0 for at least five minutes. (Uthe 1971; Saito 1962). Storage: Store at 2-8°C. Form: lyophilized powder. Source: Crotalus adamanteus Venom. Species: Crotalus. EC 3.1.1.4; Phospholipases A2; PLA2s. Cat No: NATE-0591. | |
| Native Sheep Cyclooxygenase 1 | COX-1 catalyzes the conversion of arachidonic acid to prostaglandin H2 (the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins). It is involved in the homeostatic role of eicosanoids and constitutively almost all animal tissues. Has an apparent KM of 8.3 μM for arachidonic acid. Group: Enzymes. Synonyms: COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Enzyme Commission Number: EC 1.14.99.1. CAS No. 9055-65-6. Purity: > 95% (SDS-PAGE). COX-1. Mole weight: dimer subunit mol wt 70 kDa. Activity: > 40,000 units/mg protein. Storage: -70°C. Form: aqueous solution. Solution in 80 mM Tris-HCl, pH 8, with 0.1% TWEEN 20 and 300 μM diethyldithiocarbamate. Source: Sheep. COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: NATE-0149. | |
| Pranoprofen | Pranoprofen is a non-steroidal anti-inflammatory agent ( NSAID ) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52549-17-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0336. | |
| Prostaglandin D2 | Prostaglandin D2 (PGD2) is the major eicosanoid product found in mast cells and brain. It has been shown to induce inflammation such as allergic asthma. Synonyms: PGD2; 11-Dehydroprostaglandin F2-alpha; (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid. Grades: ≥95%. CAS No. 41598-07-6. Molecular formula: C20H32O5. Mole weight: 352.5. | |
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