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Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences.
Worldwide
Eicosapentaenoic Acid
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grades: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46.
Eicosapentaenoic Acid
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA; Timnodonic acid. CAS No. 10417-94-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0660.
Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d 5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: EPA-d5; Timnodonic acid-d5. CAS No. 1197205-73-4. Pack Sizes: 1 mg (1.63 mM * 2 mL in Ethanol). Product ID: HY-B0660S.
Eicosapentaenoic acid ethyl ester
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0747.
18-Hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoic Acid is produced by non-enzymatic oxidation of Eicosapentaenoic Acid (E477800). Group: Biochemicals. Grades: Highly Purified. CAS No. 141110-17-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H30O3, Molecular Weight: 318.45. US Biological Life Sciences.
Worldwide
cis-5,8,11,14,17-Eicosapentaenoic acid
reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis. CAS No. 73167-03-0. Product ID: 1-01079. Molecular formula: C20H30O2. Mole weight: 302.46. Reference: Lancet., 15, 117, 1978; New Engl. J. Med., 314, 937, 1986.
cis-5,8,11,14,17-Eicosapentaenoic acidethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosapentaenoic acid ethyl ester. Product Category: Fatty Acids and Ester Homologs. Appearance: Solid. CAS No. 86227-47-6. Molecular formula: C22H34O2. Mole weight: 330.52. Purity: 99%+. Product ID: ACM86227476. Alfa Chemistry ISO 9001:2015 Certified. Categories: ethyl icosapentate.
cis-5,8,11,14,17-Eicosapentaenoic acidmethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EPA methyl ester. Product Category: Fatty Acids and Ester Homologs. Appearance: Colourless Oil. CAS No. 2734-47-6. Molecular formula: C21H32O2. Mole weight: 316.5. Purity: 99%+. Product ID: ACM2734476-1. Alfa Chemistry ISO 9001:2015 Certified.
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA. CAS No. 86282-92-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol); 50 μg (314.02 μM * 500 μL in Ethanol). Product ID: HY-130675A.
15(S)-HEPE
15(S)-HEPE is a polyunsaturated fatty acid that is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. Synonyms: 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid. Grades: ≥95%. CAS No. 86282-92-0. Molecular formula: C20H30O3. Mole weight: 318.45.
(±)17(18)-EpETE-Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. It is formed from the endocannabinoid eicosapentaenoic ethanolamide (EPEA) via cytochrome P450 (CYP) epoxygenases and hydrolyzed by soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH). Synonyms: 17,18-EEQ-EA; (±)17,18-EEQ-Ethanolamide; (±)17(18)-EpETE-EA; 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide. Grades: ≥98%. CAS No. 2123491-23-4. Molecular formula: C22H35NO3. Mole weight: 361.5.
(17R,18S)-Epoxyeicosatetraenoic acid
(17R,18S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EETeTr) is a cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid (HY-B0660). (17R,18S)-Epoxyeicosatetraenoic acid shows exerts negative chronotropic effects and protects neonatal rat cardiomyocytes against Ca 2+ overload. (17R,18S)-Epoxyeicosatetraenoic acid has the potential for the research of antiarrhythmic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17(R),18(S)-EETeTr. CAS No. 725246-18-4. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol). Product ID: HY-113040A.
(±)18-Hepe
(±)18-Hepe. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID;(+/-)18-HEPE. Product Category: Heterocyclic Organic Compound. Appearance: A solution in ethanol. CAS No. 141110-17-0. Molecular formula: C20H30O3. Mole weight: 318.45. Purity: 0.97. Canonical SMILES: CCC(O)\\\\C=C\\\\C=C\\\\C/C=C\\\\C/C=C\\\\C/C=C\\\\CCCC(=O)O. Product ID: ACM141110170. Alfa Chemistry ISO 9001:2015 Certified.
18-HEPE
18-HEPE (18-Hydroxy-5(Z), 8(Z), 11(Z), 14(Z), 16(E)-eicosapentaenoic acid) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 18-Hydroxy-5(Z), 8(Z), 11(Z), 14(Z), 16(E)-eicosapentaenoic acid. CAS No. 141110-17-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol). Product ID: HY-101495.
20-HEPE
20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. Grades: ≥95%. CAS No. 116477-57-7. Molecular formula: C20H30O3. Mole weight: 318.5.
5,6-DiHETE
5,6-DiHETE is an anti-inflammatory lipid mediator derived from eicosapentaenoic acid (EPA). 5,6-DiHETE has the ability to suppress vascular hyperpermeability during inflammation and is used in the research of inflammatory diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845673-97-4. Pack Sizes: 10 mM * 1 mL; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130138C.
Glycidyl Eicosapentaenoate-d5
A labeled monoacylglycerol used in the preparation of triacylglycerols acylated with n-3 polyunsaturated fatty acids for nutritional applications. Group: Biochemicals. Alternative Names: (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid Glycidyl-d5 Ester; EPA Glycidyl-d5 Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Leukotriene B5
Leukotriene B5 is a leukotriene generated from eicosapentaenoic acid (EPA). LTB5 exhibits less potent biological activity than LTB4, thus it can be identified as a LTB4 antagonist. Study showed that LTB5 inhibited LTB4-induced chemotaxis in vitro and LTB4-induced proliferation in cultured human epidermal keratinocytes. Synonyms: LTB5; 5,12-DiHEPE; 5S,12S-dihydroxy-6Z,8E,14Z,17Z-eicosapentanenoic acid. Grades: ≥98%. CAS No. 80445-66-5. Molecular formula: C20H30O4. Mole weight: 334.5.
Resolvin E1
Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: RvE1. CAS No. 552830-51-0. Pack Sizes: 10 μg (285.3 μM * 100 μL in Ethanol); 25 μg (285.3 μM * 250 μL in Ethanol). Product ID: HY-114041.
Stearidonic acid
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an intermediate fatty acid in the biosynthetic pathway from α-linolenic acid to VLC ω-3 PUFA. The conversion efficiency of stearidonic acid is higher than that of alpha-linolenic acid. Increasing the intake of stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can also be isolated from methanolic extracts of the brown alga Brachyphyllum gracilis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 6Z,9Z,12Z,15Z-Octadecatetraenoic acid. CAS No. 20290-75-9. Pack Sizes: 1 mg (36.18 mM * 100 μL in Ethanol); 5 mg (36.18 mM * 500 μL in Ethanol); 10 mg (36.18 mM * 1 mL in Ethanol). Product ID: HY-113120.
2-Eicosapentaenoyl-sn-glycerol-3-phosphocholine-d5 is labelled 2-Eicosapentaenoyl-sn-glycerol-3-phosphocholine (E477890) which is a poly unsaturated fatty acid derivative. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C28H43D5NO7P, Molecular Weight: 546.69. US Biological Life Sciences.
Worldwide
polyenoic fatty acid isomerase
The enzyme from the red alga Ptilota filicina catalyses the isomerization of skip dienes (methylene-interrupted double bonds) in a broad range of fatty acids and fatty-acid analogues, such as arachidonate and γ-linolenate, to yield a conjugated triene. Group: Enzymes. Synonyms: PFI; eicosapentaenoate cis-Δ5,8,11,14,17-eicosapentaenoate cis-Δ5-trans-Δ7,9-cis-Δ14,17 isomerase; (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Δ8,11-Δ7,8-isomerase (incorrect); (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Δ8,11-Δ7,9-isomerase (trans-double-bond-forming). Enzyme Commission Number: EC 5.3.3.13. CAS No. 159002-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5493; polyenoic fatty acid isomerase; EC 5.3.3.13; 159002-84-3; PFI; eicosapentaenoate cis-Δ5,8,11,14,17-eicosapentaenoate cis-Δ5-trans-Δ7,9-cis-Δ14,17 isomerase; (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Δ8,11-Δ7,8-isomerase (incorrect); (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate Δ8,11-Δ7,9-isomerase (trans-double-bond-forming). Cat No: EXWM-5493.
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