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Eletriptan is Serotonin 1D receptor agonist originated by Pfizer. It is a second generation triptan drug. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan was approved by the FDA for the acute treatment of migraine with or without aura in adults in 2002. Uses: Menstrual migraine; migraine. Synonyms: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole; (R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole; Eletriptan; UK 116044; UK-116,044; UK-116,044-04 [as hydrobromide]; UNII-22QOO9B8KI; Relpax free amine. Grades: 98%. CAS No. 143322-58-1. Molecular formula: C22H26N2O2S. Mole weight: 382.52.
Eletriptan induces concentration-dependent contractions of meningeal artery, coronary artery, and saphenous vein. The potency of Eletriptan is higher in meningeal artery than in coronary artery (86-fold) or saphenous vein (66-fold). Synonyms: Eletriptan Hydrobromide; CHEBI:61176; M41W832TA3; UNII-M41W832TA3; eletriptan hydrobromide; Relpax; UK 166,044; UK 166044; UK-166,044; UK-166044. Grades: >98%. CAS No. 177834-92-3. Molecular formula: C22H26N2O2S.HBr. Mole weight: 463.43.
Eletriptan hydrobromide
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT 1B and 5-HT 1D receptor agonist with antimigraine activity, with K i of 0.92 nM and 3.14 nM, respectively [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eletriptan HBr; UK-116044 hydrobromide. CAS No. 177834-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0010.
Eletriptan hydrobromide
Eletriptan hydrobromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 177834-92-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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Eletriptan Impuirty 1
Eletriptan Impuirty 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153525-55-4. Molecular Formula: C21H24N2O2S. Mole Weight: 368.5. Catalog: APB153525554.
Eletriptan N-oxide
An impurity of Eletriptan. Synonyms: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole N Oxide. Grades: > 95%. CAS No. 1217641-89-8. Molecular formula: C22H26N2O3S. Mole weight: 398.53.
Eletriptan N-Oxide
An impurity of Eletriptan. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole N Oxide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A serotonin 5-HTIB/ID receptor agonist. Group: Biochemicals. Alternative Names: UK-116044, Relpax, 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ent-eletriptan
ent-eletriptan. Group: Biochemicals. Alternative Names: 3-[[(2S)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole. Grades: Highly Purified. CAS No. 1252673-29-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H26N2O2S. US Biological Life Sciences.
Worldwide
N-Acetyl-dehydro-Eletriptan
N-Acetyl-dehydro-Eletriptan. Group: Biochemicals. Alternative Names: 1-Acetyl-3-[[ (2R) -1-methyl-2-pyrrolidinyl]methyl]-5-[2- (phenylsulfonyl) ethenyl]-1H-indole; (R,E)-1-(3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indol-1-yl)ethanone. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C24H26N2O3S, Molecular Weight: 422.54. US Biological Life Sciences.
Worldwide
N-Acetyl-dehydro-Eletriptan
N-Acetyl-dehydro-Eletriptan is an impurity of Eletriptan, a serotonin 5-HTIB/ID receptor agonist used in the treatment of migraine. Synonyms: 1-Acetyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole. CAS No. 188113-71-5. Molecular formula: C24H26N2O3S. Mole weight: 422.54.
N-Desmethyl eletriptan hydrochloride
N-Desmethyl Eletriptan is the N-demethylated analogue of the serotonin 5-HT1 receptor agonist, Eletriptan. Synonyms: (R)-5-[2-(Phenylsulfonyl)ethyl]-3-(2-pyrrolidinylmethyl)-1H-indole Hydrochloride. Grades: > 95%. CAS No. 1391054-78-6. Molecular formula: C21H24N2O2S.HCl. Mole weight: 404.95.
1,2,3,5,10,10a-Hexahydro-4-methyl-8-[2-(phenylsulfonyl)ethyl]-pyrrolizino[3,2-b]indolium Bromide is a bromide form of 1,2,3,5,10,10a-Hexahydro-4-methyl-8-[2-(phenylsulfonyl)ethyl]-pyrrolizino[3,2-b]indolium which is an impurity of Tetracyclic Eletriptan and can be used as analyte in analytical study and synthetic preparation for synthesis of compounds related to antimigraine drug Eletriptan hydrobromide (impurity profile). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C22H25BrN2O2S. US Biological Life Sciences.
3-[[ (2S) -1-Methyl-2-pyrrolidinyl]methyl]-5-[ (1E) -2- (phenylsulfonyl) ethenyl]-1H-indole is an intermediate in the synthesis of ent-Eletriptan (E505005), an enantiomeric impurity of the serotonin 5-HTIB/ID receptor agonist Eletriptan (E505000). Group: Biochemicals. Grades: Highly Purified. CAS No. 362595-66-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H24N2O2S. US Biological Life Sciences.
5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole-d5. Group: Biochemicals. Alternative Names: Eletriptan Impurity-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C16H17D5N2, Molecular Weight: 242.36. US Biological Life Sciences.
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Relpax
A second generation triptan drug used in the treatment of migraine headaches. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole Hydrobromide; Eletriptan Hydrobromide; (R) -5-[2- (Benzenesulfonyl) ethyl]-3-[ (N-methylpyrrolidin-2-yl) methyl]-1H-indole Hydrobromide; Relert; UK 116044-04. Grades: Highly Purified. CAS No. 177834-92-3. Pack Sizes: 10mg. US Biological Life Sciences.