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| Product | Description | |
|---|---|---|
| Ellipticine | Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Group: Inhibitors. Alternative Names: 5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;ELLIPTICINE;3-b)carbazole,5,11-dimethyl-6h-pyrido(;icig770;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG). CAS No. 519-23-3. Molecular formula: C17H14N2. Mole weight: 246.31. Density: 1.257±0.06 g/cm³ (20 ºC 760 Torr). Catalog: ACM519233. |  |
| Ellipticine | Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795. CAS No. 519-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15753. |  |
| Ellipticine hydrochloride | Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795 hydrochloride. CAS No. 5081-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15753A. | |
| Ellipticine (NSC 71795) | Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in target tissues. Ellipticine has been shown to inhibit the proliferation of human breast adenocarcinoma MCF-7 cells, leukemia HL-60 and CCRF-CEM cells, neuroblastoma IMR-32, UKF-NB-3, and UKF-NB-4 cells, and U87MG glioblastoma cells with IC50 values ranging from 0.27-4.7uM. Group: Biochemicals. Alternative Names: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole, NSC 71795. Grades: Highly Purified. CAS No. 519-23-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14N2, Molecular Weight: 246.3. US Biological Life Sciences. |  Worldwide |
| Celiptium | Celiptium, also known as elliptinium acetate, a topoisomerase II inhibitor, is the acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis. Check for active clinical trials or closed clinical trials using this agent. Uses: Antineoplastic agents. Synonyms: Ellipticine acetate; Elliptinium acetate; Celiptium; 9-HME; HME; NMHE; 9-hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium acetate. Grades: 98%. CAS No. 58337-35-2. Molecular formula: C20H20N2O3. Mole weight: 336.39. |  |
| Datelliptium chloride | Datelliptium chloride, derived from ellipticine, is a DNA-intercalating agent with good activity in murine tumor models over a broad range of doses. Synonyms: 2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol;chloride; 2-(diethylamino-2-ethyl)-9-hydroxyellipticinium; 2-DEHE; datelliptium chloride; detalliptinium; detalliptinium acetate salt; detalliptinium chloride; detalliptium acetate; diethylaminoethyl-2-OH-9-ellipticinium; NSC 311152; NSC 626718X; NSC-311152; SR 95156A; SR 95156B; SR-95156A. CAS No. 105118-14-7. Molecular formula: C23H28ClN3O. Mole weight: 397.94. | |
| Datelliptium chloride | Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 105118-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00337. | |
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