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Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 ( SGLT-2 ) inhibitor with an IC 50 of 3.1 nM for human SGLT-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 10773. CAS No. 864070-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15409.
Empagliflozin
Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Synonyms: BI10773; BI-10773; BI 10773; CE0108; CS0940; PB23119; VA10802; AJ93046; Empagliflozin; trade name Jardiance. Grades: >98%. CAS No. 864070-44-0. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin
Potent, selective and competitive inhibitor of sodium-glucose cotransporter SGLT2, which is implicated in renal glucose reabsorption. The compound increases urinary glucose excretion, helps decrease hyperglyceamia and maintains glucose homeostasis in diabetic individuals. It has been associated with weight loss, lower blood pressure and decreased glycated haemoglobin. Animal studies suggest that empagliflozin preserves regeneration of β-cells in pancreatic Langerhans islets. Group: Biochemicals. Alternative Names: (1S) -1, 5-Anhydro-1-C- [4-chloro-3- [ [4- [ [ (3S) -tetrahydro-3-furanyl] oxy] phenyl] methyl] phenyl] -D-glucitol. Grades: Highly Purified. CAS No. 864070-44-0. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C23H27ClO7, Molecular Weight: 450.91. US Biological Life Sciences.
Worldwide
Empagliflozin 6-O-b-D-glucuronide
Empagliflozin 6-O-b-D-glucuronide is a drug metabolite within the biomedical industry, acting as an invaluable role in the research of diabetes and concomitant metabolic maladies. Demonstrating remarkable efficacy, this compound effectively impedes the functional activity of the sodium-glucose cotransporter 2 (SGLT2). Molecular formula: C29H35ClO13. Mole weight: 627.03.
Empagliflozin α Isomer
Empagliflozin α Isomer is an isomer of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Empagliflozin α-Anomer; (2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1620758-33-9. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin-d4
Empagliflozin-d 4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BI 10773-d4. CAS No. 2749293-95-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15409S.
Empagliflozin Destetrahydrofuran Impurity
An impurity of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: O-Desethyl Dapagliflozin; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: 98%. CAS No. 864070-37-1. Molecular formula: C19H21ClNO6. Mole weight: 380.83.
Empagliflozin Impurity 107
Empagliflozin Impurity 107. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-tetrahydrofuran-3-yl formate. CAS No. 167979-56-8. Molecular formula: C5H8O3. Mole weight: 116.12. Catalog: APB167979568.
Empagliflozin Impurity 141
Empagliflozin Impurity 141. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dibromo-5-chlorobenzoic acid. CAS No. 150812-33-2. Molecular formula: C7H3Br2ClO2. Mole weight: 314.36. Catalog: APB150812332.
Empagliflozin Impurity 17
An impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol; Tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl). CAS No. 2452301-27-6. Molecular formula: C23H28O7. Mole weight: 416.46.
Empagliflozin Methyl Acetate is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: ((2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl Acetate. CAS No. 2452301-09-4. Molecular formula: C25H29ClO8. Mole weight: 492.95.
Empagliflozin Ortho Isomer
Empagliflozin Ortho Isomer is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2452301-30-1. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin R-Furanose
Empagliflozin R-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Canagliflozine Furanose Impurity; (2R,3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-31-7. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin S-Furanose
Empagliflozin S-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Jardiance Impurity C; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-32-8. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin Tetraacetoxy
Empagliflozin Tetraacetoxy is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl Triacetate. CAS No. 1620758-21-5. Molecular formula: C32H37ClO12. Mole weight: 649.08.
1,4-Anhydro-1,5-dihydroxy-1-methoxyempagliflozin
1,4-Anhydro-1,5-dihydroxy-1-methoxyempagliflozin is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C24H29ClO8, Molecular Weight: 480.94. US Biological Life Sciences.
Worldwide
1,4-Anhydro-1,5-dihydroxy-3-epi-empagliflozin
1,4-Anhydro-1,5-dihydroxy-3-epi-empagliflozin is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H27ClO7, Molecular Weight: 450.91. US Biological Life Sciences.
1,4-Anhydro-1,5-dihydroxy-3-epi-empagliflozin-d4 is labelled 1,4-Anhydro-1,5-dihydroxy-3-epi-empagliflozin (A637885), an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H23D4ClO7, Molecular Weight: 454.93. US Biological Life Sciences.
Worldwide
1,4-Anhydro-1,5-dihydroxy-empagliflozin
1,4-Anhydro-1,5-dihydroxy-empagliflozin is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H27ClO7, Molecular Weight: 450.91. US Biological Life Sciences.
Worldwide
1,4-Anhydro-1,5-dihydroxy-empagliflozin-d4
1,4-Anhydro-1,5-dihydroxy-empagliflozin-d4 is labelled 1,4-Anhydro-1,5-dihydroxy-empagliflozin (A637895), an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H23D4ClO7, Molecular Weight: 454.93. US Biological Life Sciences.
Worldwide
1-Hydroxy Empagliflozin
1-Hydroxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2). Group: Biochemicals. Grades: Highly Purified. CAS No. 1279691-35-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C23H27ClO8, Molecular Weight: 466.91. US Biological Life Sciences.
Worldwide
1-Hydroxy Empagliflozin
1-Hydroxy Empagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: 1-C-[4-Chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-α-D-glucopyranose; (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol. CAS No. 1279691-35-8. Molecular formula: C23H27ClO8. Mole weight: 466.91.
1-Methoxy Empagliflozin
1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2). Group: Biochemicals. Grades: Highly Purified. CAS No. 1279691-36-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H29ClO8, Molecular Weight: 480.94. US Biological Life Sciences.
Worldwide
(1R)-1,5-Dihydroxyempagliflozin
(1R)-1,5-Dihydroxyempagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1R) ?-1-C- [4-Chloro-3- [ [4- [ [ (3S) ?-tetrahydro-3-furanyl] ?oxy] ?phenyl] ?methyl] ?phenyl] ?-D-glucitol. Grades: > 95%. CAS No. 1620758-34-0. Molecular formula: C23H29ClO8. Mole weight: 468.92.
(1R)-1,5-Dihydroxyempagliflozin
(1R)-1,5,-Dihydroxyempagliflozin is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 1620758-34-0. Pack Sizes: 1mg. Molecular Formula: C23H29ClO8, Molecular Weight: 468.92. US Biological Life Sciences.
Worldwide
(1R)-1,5-Dihydroxyempagliflozin-d4
(1R)-1,5,-Dihydroxyempagliflozin-d4 is labelled (1R)-1,5,-Dihydroxyempagliflozin (D452715), an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H25D4ClO8, Molecular Weight: 472.95. US Biological Life Sciences.
Worldwide
Des(tetrahydrofuran) Empagliflozin Tetraacetate
Des(tetrahydrofuran) Empagliflozin Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, 2,3,4,6-tetraacetate D-Glucitol; (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 1079083-63-8. Molecular formula: C27H29ClO10. Mole weight: 548.97.
Hydroxy Empagliflozin
Hydroxy Empagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[hydroxy[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(hydroxy(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2137418-13-2. Molecular formula: C23H27ClO8. Mole weight: 466.91.
Methoxy Empagliflozin
Methoxy Empagliflozin is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate; 1,5-Anhydro-1-C-[4-chloro-3-[(4-methoxyphenyl)methyl]phenyl]-, 2,3,4,6-tetraacetate-D-glucitol. CAS No. 872980-38-6. Molecular formula: C28H31ClO10. Mole weight: 562.99.
Peracetyl Empagliflozin
Peracetyl Empagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Tetraacetate. CAS No. 915095-99-7. Molecular formula: C31H35ClO11. Mole weight: 619.06.
1,2:3,4:5,6-Tri-O-isopropylidene-D-gluconate
1,2:3,4:5,6-Tri-O-isopropylidene-D-gluconate, a crucial synthetic intermediate for various drugs including dapagliflozin, empagliflozin, and canagliflozin, among others, has gained significant spotlight in the pharmaceutical industry for its role in treating type 2 diabetes. Its usage as an intermediary has created a promising avenue for medical synthesis and research, thereby augmenting the application of this compound in diverse fields. CAS No. 52492-60-1. Molecular formula: C15H24O7. Mole weight: 316.35.
(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2-Chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methanone; (1S)-1,5-Anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydro-3-furanyloxy]benzoyl}phenyl)-D-glucitol. CAS No. 2125472-55-9. Molecular formula: C23H25ClO8. Mole weight: 464.89.
(2-Chloro-5-iodophenyl) [4- [ [ (3S) -tetrahydro-3-furanyl] oxy] phenyl] methanone is an intermediate of Empagliflozin (E521510) which is a potent and selective SGLT-2 inhibitor that improves glycaemic control syndrome in diabetic rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 915095-87-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H14ClIO3. US Biological Life Sciences.
Worldwide
(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone
(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone is a reagent in the synthesis of Empagliflozin (E521510); an inhibitor of SGLT-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 915095-86-2. Pack Sizes: 250mg, 1g. Molecular Formula: C13H7ClFIO. US Biological Life Sciences.
(2R,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. CAS No. 2452301-42-5. Molecular formula: C23H27ClO7. Mole weight: 450.91.
(2R,3R,4R,5S,6R)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. CAS No. 1620758-27-1. Molecular formula: C31H35ClO11. Mole weight: 619.06.
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone; 915095-85-1; (5-bromo-2-chlorophenyl)-(4-fluorophenyl)methanone; C13H7BrClFO; SCHEMBL2637828; AMY39947; MFCD12410140; AKOS005831751; 5-Bromo-2-Chloro-4'-Fluorobenzophenone; BS-17834; CS-0162265; D84028; (5-bromo-2-chlorophenyl)(4-fluorophenyl) methanone; Methanone, (5-bromo-2-chlorophenyl)(4-fluorophenyl)-. CAS No. 915095-85-1. Molecular formula: C13H7BrClFO. Mole weight: 313.55.
Methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-α-D-glucopyranoside is a remarkable compound, used in studying a myriad of ailments such as tumors. Synonyms: (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol; (2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methoxy empagliflozin; Methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-alpha-D-glucopyranoside; 1-Methoxy Empagliflozin; UCE3CY4NYM; (2S,3R,4S,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol; alpha-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-; (3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol. CAS No. 1279691-36-9. Molecular formula: C24H29ClO8. Mole weight: 480.93.
(R)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (3R)-3-[4-(5-Bromo-2-chlorobenzyl)phenoxy]tetrahydrofuran. CAS No. 915095-90-8. Molecular formula: C17H16BrClO2. Mole weight: 367.66.
(S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (3S) -3-[4-[ (5-Bromo-2-chlorophenyl) methyl]phenoxy]tetrahydrofuran; Empagliflozin Impurity I. CAS No. 915095-89-5. Molecular formula: C17H16BrClO2. Mole weight: 367.66.
(S)-(5-bromo-2-chlorophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (5-Bromo-2-chlorophenyl){4-[(3S)-tetrahydro-3-furanyloxy]phenyl}methanone. CAS No. 915095-84-0. Molecular formula: C17H14BrClO3. Mole weight: 381.65.
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