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| Product | Description | |
|---|---|---|
| Endoxifen | Endoxifen. Group: Biochemicals. Grades: Purified. CAS No. 112093-28-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Endoxifen | Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 110025-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719E. |  |
| Endoxifen E-isomer hydrochloride | Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-Endoxifen hydrochloride. CAS No. 1197194-61-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-18719C. | |
| Endoxifen E-isomer hydrochloride | The hydrochloride salt form of E-isomer of Endoxifen which is a significant metamolite of Tamoxifen, could be a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Uses: The hydrochloride salt form of e-isomer of endoxifen which could be a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Synonyms: E-Endoxifen hydrochloride. Grades: 98%. CAS No. 1197194-61-8. Molecular formula: C25H28ClNO2. Mole weight: 409.95. |  |
| Endoxifen HCl | Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2. Endoxifen shows anti-estrogenic effects, and decreases the E2-induced PR expression in MCF-7 cells. In vivo, Endoxifen (8 mg/kg, ) inhibits growth of MCF-7 human mammary tumor xenografts in mice. Synonyms: Z-Endoxifen HCl; Z Endoxifen HCl; ZEndoxifen HCl; Z Endoxifen Hydrochloride; ZEndoxifen Hydrochloride. Grades: 98%. CAS No. 1032008-74-4. Molecular formula: C25H28ClNO2. Mole weight: 409.95. | |
| Endoxifen hydrochloride | Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197194-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719B. | |
| Endoxifen hydrochloride | Endoxifen hydrochloride is a metabolite of Tamoxifen and a selective estrogen receptor modulator (SERM) that inhibits the growth of estrogen-stimulated BT474 cells (IC50 = 54 nM). Endoxifen is used for the treatment of estrogen receptor (ER) positive breast cancer. Uses: Anticancer drug. Synonyms: 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-Phenol hydrochloride (1:1). Grades: 99%. CAS No. 1197194-41-4. Molecular formula: C25H28ClNO2. Mole weight: 409.95. | |
| (E/Z)-Endoxifen | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: > 95%. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.50. | |
| N-Desmethyl-4-hydroxytamoxifen (1:1 E/Z Mixture) (E/Z Endoxifen) | A metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: E/Z Endoxifen, 4OHNDtam, 4-[1-[4-[2- (methylamino) ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: Highly Purified. CAS No. 110025-28-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Desmethyl-4-hydroxytamoxifen-ethyl-d5 (1:1 E/Z Mixture) (E/Z Endoxifen-d5) | A labeled metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: E/Z Endoxifen-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (Z)-4-Hydroxy-N-Desmethyl Tamoxifen (Endoxifen) | Endoxifen, a significant metamolite of Tamoxifen, is a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. IC50: 1.6 μM. Uses: Endoxifen is a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Synonyms: 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol. Grades: >98 %. CAS No. 112093-28-4. Molecular formula: C25H27NO2. Mole weight: 373.49. | |
| (E/Z)-4,4-Dihydroxy-N-desmethyl Tamoxifen | A Tamoxifen analog. Group: Biochemicals. Alternative Names: (E/Z)-4-Hydroxy Endoxifen. Grades: Highly Purified. CAS No. 1217247-19-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Desmethyl-4-hydroxy tamoxifen(approx. 1:1 e/z mixture) | Heterocyclic Organic Compound. Alternative Names: 4-[1-[4-[2- (methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; 4OHNDtam; E/Z Endoxifen;N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture);4-hydroxy-N-desmethyltamoxifen;4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol;4-[(Z)-1-. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.493. Appearance: Brown Foam. Catalog: ACM110025280. |  |
| N-Desmethyl-4-hydroxy Tamoxifen-d5 β-D-Glucuronide (E/Z Mixture) | A novel active labeled metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: 4-[1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl-d5 β-D-Glucopyranosiduronic Acid; (E/Z)-Endoxifen Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Desmethyl-4-hydroxy Tamoxifen-d5 Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester (E/Z Mixture) | Protected, labeled Tamoxifen metabolite. Group: Biochemicals. Alternative Names: 4-[1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl-d5 Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester; (E/Z)-Endoxifen-d5 Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tamoxifen | Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. Group: Biochemicals. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; Mammaton; Novaldex; Tamoxifen; Z-Tamoxifen. Grades: Highly Purified. CAS No. 10540-29-1. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
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