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| Product | Description | |
|---|---|---|
| Entacapone | (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide. CAS No. 130929-57-6. Product ID: 8-01557. Molecular formula: C14H15N3O5. Mole weight: 305.29. Purity: 0.99. |  |
| Entacapone | Entacapone. Group: Biochemicals. Grades: Purified. CAS No. 130929-57-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Entacapone | Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC 50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC 50 s>50 μM). Entacapone can be used for the research of Parkinson's disease [1]. Entacapone serves as a inhibitor of FTO demethylation with an IC 50 of 3.5 μM, can be used for the research of metabolic disorders [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130929-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14280. |  |
| Entacapone | Entacapone is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) (IC50 = 151 nM), commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2E)-; Comtan; HSDB 8251; HSDB-8251; HSDB8251; OR-611; OR 611; OR611; (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (E)-; (E)-Entacapone; Comtess; Entacom; Parkicapone. Grades: >98%. CAS No. 130929-57-6. Molecular formula: C14H15N3O5. Mole weight: 305.29. |  |
| Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide) | Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3nm for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits alpha-synuclein aggregation in an in vitro assay; blocks alpha-synuclein-induced cell death in PC-12 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 130929-57-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide,. OR-611, Comtan, Comtess) | Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; OR-611; Comtan; Comtess. Grades: Highly Purified. CAS No. 130929-57-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Entacapone 3-b-D-glucuronide | Entacapone 3-b-D-glucuronide is a metabolite of Entacapone, which is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) used in combination with other medications for the treatment of Parkinson's disease. Synonyms: β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl; 5-[(1E)-2-Cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl; β-D-Glucopyranosiduronic acid, 5-[2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl, (E)-; Entacapone 3-β-D-glucuronide. Grades: ≥95%. CAS No. 158069-75-1. Molecular formula: C20H23N3O11. Mole weight: 481.41. | |
| Entacapone-3-sulfate Sodium Salt | Entacapone-3-sulfate Sodium Salt. Group: Biochemicals. Alternative Names: (E)-2-Cyano-N,N-diethyl-3-[4-hydroxy-3-nitro-5-(sulfooxy)phenyl]-2-propenamide Sodium Salt. Grades: Highly Purified. CAS No. 158069-72-8. Pack Sizes: 5mg. Molecular Formula: C14H14N3NaO8S, Molecular Weight: 407.33. US Biological Life Sciences. | Worldwide |
| Entacapone-d10 | (E)-Isomer of labeled Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-di-(ethyl-d5)-2-propenamide; OR-611-d10; Comtan-d10; Comtess-d10. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Entacapone EP Impurity A | Isomer of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: cis-Entacapone; (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; (Z)-Entacapone. Grades: > 95%. CAS No. 145195-63-7. Molecular formula: C14H15N3O5. Mole weight: 305.29. | |
| Entacapone EP Impurity B | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: Ethyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate. Grades: > 95%. Molecular formula: C12H10N2O6. Mole weight: 278.22. | |
| Entacapone EP Impurity C | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: 3,4-Dihydroxy-5-nitrobenzaldehyde. Grades: > 95%. CAS No. 116313-85-0. Molecular formula: C7H5NO5. Mole weight: 183.12. | |
| Entacapone EP Impurity D | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide. Grades: > 95%. CAS No. 857629-79-9. Molecular formula: C16H19N3O5. Mole weight: 333.35. | |
| Entacapone EP Impurity E | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: 3,5-Dinitrobenzene-1,2-diol ; 1,2-Dihydroxy-3,5-dinitrobenzene. Grades: > 95%. CAS No. 7659-29-2. Molecular formula: C6H4N2O6. Mole weight: 200.11. | |
| Entacapone EP Impurity F | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: Entacapone acid; (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoic acid; 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, (2E)-; (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-2-propenoic acid; 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, (E)-; AG 1290; Tyrphostin AG 1290. Grades: ≥95%. CAS No. 160391-70-8. Molecular formula: C10H6N2O6. Mole weight: 250.17. | |
| Entacapone EP Impurity G | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-prop-2-enamide. Grades: > 95%. CAS No. 1364322-41-7. Molecular formula: C11H9N3O5. Mole weight: 263.21. | |
| Entacapone EP Impurity H | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile. Grades: > 95%. CAS No. 1150310-15-8. Molecular formula: C15H15N3O5. Mole weight: 317.30. | |
| Entacapone EP Impurity I | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: Propyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate. Grades: > 95%. CAS No. 1364322-42-8. Molecular formula: C13H12N2O6. Mole weight: 292.25. | |
| Entacapone Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Entacapone sodium salt | Entacapone is a specific, potent catechol-O-methyl transferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. Synonyms: Entacapone sodium salt; 1047659-02-8; Entacapone (sodium salt); Entacapone Sodiumsodium; 4-[(E)-2-cyano-3-(diethylamino)-3-oxoprop-1-enyl]-2-hydroxy-6-nitrophenolate. Grades: >98%. CAS No. 1047659-02-8. Molecular formula: C14H14N3NaO5. Mole weight: 327.27. | |
| cis-Entacapone | cis-Entacapone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Entacapone Imp. A (EP), Entacapone USP Related Compound A, Entacapone USP RC A, (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide. CAS No. 145195-63-7. IUPAC Name: (Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide. Molecular formula: C14H15N3O5. Mole weight: 305.29. Catalog: APS145195637. SMILES: CCN(CC)C(=O)\C(=C/c1cc(O)c(O)c(c1)[N+](=O)[O-])\C#N. Format: Neat. | |
| cis-Entacapone | (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; (Z)-Entacapone. Grades: Highly Purified. CAS No. 145195-63-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| cis-Entacapone-3-sulfate Sodium Salt | cis-Entacapone-3-sulfate Sodium Salt. Group: Biochemicals. Alternative Names: (Z)-2-Cyano-N,N-diethyl-3-[4-hydroxy-3-nitro-5-(sulfooxy)phenyl]-2-propenamide Sodium Salt. Grades: Highly Purified. CAS No. 158069-74-0. Pack Sizes: 1mg. Molecular Formula: C14H14N3NaO8S, Molecular Weight: 407.33. US Biological Life Sciences. | Worldwide |
| cis-Entacapone-d10 | Labeled analogue of cis-Entacapone, the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide-d10; (Z)-Entacapone-d10. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (E)-3-O-Methyl entacapone | (E)-3-O-Methyl entacapone. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide; Entacapone 3-methyl ether. Grades: Highly Purified. CAS No. 857629-78-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H17N3O5. US Biological Life Sciences. | Worldwide |
| (E)-3-O-Methyl entacapone | (E)-3-O-Methyl entacapone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide; Entacapone 3-Methyl Ether. Product Category: Heterocyclic Organic Compound. CAS No. 857629-78-8. Molecular formula: C15H17N3O5. Mole weight: 319.31. Product ID: ACM857629788. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (E)-3-O-Methyl Entacapone | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide. Grades: > 95%. CAS No. 857629-78-8. Molecular formula: C15H17N3O5. Mole weight: 319.32. | |
| (E/Z)-3-O-Methyl entacapone | (E/Z)-3-O-Methyl entacapone. Group: Biochemicals. Alternative Names: 2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide; (E/Z)-Entacapone 3-methyl ether. Grades: Highly Purified. CAS No. 146698-91-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H17N3O5. US Biological Life Sciences. | Worldwide |
| 2, 4-Dicyano-3- (3, 4-dihydroxy-5-nitrophenyl) -N1, N1, N5, N5-tetraethylpentane diamide | 2, 4-Dicyano-3- (3, 4-dihydroxy-5-nitrophenyl) -N1, N1, N5, N5-tetraethylpentane diamide is a dimer impurity of Entacapone n (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H27N5O6, Molecular Weight: 445.47. US Biological Life Sciences. | Worldwide |
| 2, 4-Dicyano-3- (3, 4-dihydroxyphenyl) -N1, N1, N5, N5-tetraethylpentane diamide | 2, 4-Dicyano-3- (3, 4-dihydroxyphenyl) -N1, N1, N5, N5-tetraethylpentane diamide is a dimer impurity of Entacapone Vanillin (E558500) and (V097500) respectively. Entacapone acts as a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H28N4O4, Molecular Weight: 400.47. US Biological Life Sciences. | Worldwide |
| 2, 4-Dicyano-N1, N1, N5, N5-tetraethyl-3- (4-hydroxy-3-methoxy-5-nitrophenyl) pentanediamide | 2, 4-Dicyano-N1, N1, N5, N5-tetraethyl-3- (4-hydroxy-3-methoxy-5-nitrophenyl) pentanediamide is a dimer impurity of Entacapone Vanillin (E558500) and (V097500) respectively. Entacapone acts as a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H29N5O6, Molecular Weight: 459.5. US Biological Life Sciences. | Worldwide |
| 2-Cyano-3-(5-dihydroxyamino-3,4-dioxo-1-cyclohexa-1,5-dienyl)-n,n-diethyl-prop-2-enamide | 2-Cyano-3-(5-dihydroxyamino-3,4-dioxo-1-cyclohexa-1,5-dienyl)-n,n-diethyl-prop-2-enamide. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; OR-611; Comtan; Entacapone. Grades: Highly Purified. CAS No. 130929-57-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H15N3O5. US Biological Life Sciences. | Worldwide |
| (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide | (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. CAS No. 857629-79-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C16H19N3O5, Molecular Weight: 333.34. US Biological Life Sciences. | Worldwide |
| (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide-d5 | Isotope labelled (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide (C956047), an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H14D5N3O5, Molecular Weight: 338.37. US Biological Life Sciences. | Worldwide |
| 2-(Pivaloyloxy)acetic Acid | 2-(Pivaloyloxy)acetic Acid is a compound used in the synthesis and in-vitro/in-vivo evaluation of orally administered entacapone prodrugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 89941-82-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H12O4, Molecular Weight: 160.169999999999. US Biological Life Sciences. | Worldwide |
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