Enzyme Disulfide Suppliers USA
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Product | Description | |
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3- (2-Pyridyldithio) propanoic Acid Quick inquiry Where to buy Suppliers range | Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis. Group: Biochemicals. Alternative Names: 2-Carboxyethyl 2-Pyridyl Disulfide. Grades: Highly Purified. CAS No. 68617-64-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
Aprotinin Quick inquiry Where to buy Suppliers range | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. Synonyms: H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH; EC: 3.4.21.9; Iniprol; Trasylol; Trazinin; Zymofren; Riker 52G. Grades: >99%. CAS No. 9087-70-1. Molecular formula: C284H432N84O79S7. Mole weight: 6511.48. | |
Captopril-cysteine Disulfide Quick inquiry Where to buy Suppliers range | Captopril-cysteine Disulfide is an impurity of Captopril, an orally active angiotensin-converting enzyme (ACE) inhibitor. Synonyms: Captopril-cysteine; 1-[(2S)-3-[[(2R)-2-Amino-2-carboxyethyl]dithio]-2-methyl-1-oxopropyl]-L-proline. CAS No. 75479-46-8. Molecular formula: C12H20N2O5S2. Mole weight: 336.43. | |
Captopril disulfide Quick inquiry Where to buy Suppliers range | A metabolite of Captopril, an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Synonyms: 1,1'-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS; SQ 14551; Captopril Imp. A (BP); Captopril EP Impurity A. Grades: > 95%. CAS No. 64806-05-9. Molecular formula: C18H28N2O6S2. Mole weight: 432.56. | |
Captopril-N-acetylcysteine Disulfide Quick inquiry Where to buy Suppliers range | Captopril-N-acetylcysteine Disulfide is a metabolite of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: 1-[(2S)-3-[[(2R)-2-(Acetylamino)-2-carboxyethyl]dithio]-2-methyl-1-oxopropyl]-L-proline; ((S)-3-(((R)-2-acetamido-2-carboxyethyl)disulfaneyl)-2-methylpropanoyl)-L-proline; 1-[(2S)-3-{[(2R)-2-Acetamido-2-carboxyethyl]disulfanyl}-2-methylpropanoyl]-L-proline; Captopril Related Compound 10. Grades: 95%. CAS No. 78636-31-4. Molecular formula: C14H22N2O6S2. Mole weight: 378.46. | |
Cystamine dihydrochloride Quick inquiry Where to buy Suppliers range | Cystamine dihydrochloride is the dihydrochloride salt of cystamine, which is an organic disulfide that inhibits tissue transglutaminase (TGM2) with an IC50 value of approximately 2.5 mM. It is orally available, and decreases aggregated and cross-linked huntingtin in transfected cells. It is neuroprotective in mouse models of Huntington's disease. It has exhibited suppressive effects against HIV replication in infected human cells. It could extend survival and improve motor performance in transgenic HD mice. It inhibits caspase 3, increases intracellular glutathione, and reduces inflammation in a rat model of inflammatory bowel disease. Uses: Enzyme inhibitors. Synonyms: 2-(2-aminoethyldisulfanyl)ethanamine; dihydrochloride. Grades: > 97 %. CAS No. 56-17-7. Molecular formula: C4H14Cl2N2S2. Mole weight: 225.20. | |
Dimethyl Disulfide-d6 Quick inquiry Where to buy Suppliers range | Dimethyl Disulfide-d6. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: DMDS-d6, Dimethyl Disulfide-d6,(Methyldithio)methane-d6, 2,3-Dithiabutane-d6, NSC 9370-d6, Dimethyl Disulphide-d6, Paladin-d6, Dithioether-d6, Sulfa-Hitech-d6. CAS No. 7282-94-2. Pack Sizes: 10MG. IUPAC Name: trideuterio-(trideuteriomethyldisulfanyl)methane. Molecular formula: C22H6S2. Mole weight: 100.24. Catalog: APS7282942. SMILES: [2H]C([2H])([2H])SSC([2H])([2H])[2H]. Format: Neat. Product Type: Stable Isotope Labelled. Shipping: Room Temperature. | |
DX600 Quick inquiry Where to buy Suppliers range | DX600 is an inhibitor of angiotensin-converting enzyme 2 (ACE2). Synonyms: DX-600; Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2 (Disulfide bridge: Cys6-Cys17); N-{ [ (6S, 9R, 14R, 17S, 20S, 23S, 25aS, 31S, 34S, 37S, 40S, 42aS) -9- [ (N-Acetylglycyl-L-α -aspartyl-L-tyrosyl-L-seryl-L-histidyl) amino] -17- (4-aminobutyl) -37- (3-carbamimidamidopropyl) -31, 34-bis (4-hydroxybenzyl) -6- (hydroxymethyl) -20, 23-bis (1H-indol-3-ylmethyl) -40-isobutyl-5, 8, 16, 19, 22, 25, 30, 33, 36, 39, 42-undecaoxooctatriacontahydro-1H, 13H-dipyrrolo [2, 1-p: 2', 1'-e1] [1, 2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35] dithiaundecaazacyclooctatriacontin-14-yl] carbonyl}-L-threonyl-L-tyrosyl-L-prolyl-L-α -aspartyl-L-prolyl-L-α -glutamylglycylglycylglycinamide; N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide. Grades: ≥95%. CAS No. 478188-26-0. Molecular formula: C141H185N35O40S2. Mole weight: 3074.32. | |
DX600 TFA Quick inquiry Where to buy Suppliers range | DX600 TFA is an inhibitor of angiotensin-converting enzyme 2 (ACE2) and does not cross-react with ACE. Synonyms: Glycinamide, N-acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycyl-, cyclic (6?17)-disulfide, trifluoroacetate salt (1:1); Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2.TFA (Disulfide bridge: Cys6-Cys17); N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide trifluoroacetic acid. Grades: ≥95%. Molecular formula: C123H169F3N32O39S2. Mole weight: 2841.01. | |
Lanreotide Quick inquiry Where to buy Suppliers range | Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Synonyms: Angiopeptin; Autogel; BIM 23014; DC 13-116; Dermopeptin; Ipstyl; L-Autogel; Lanreotide Autogel; Somatulin; Somatulin-Autogel; Somatuline Depot; L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2?7)-disulfide; H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2; 3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grades: 98%. CAS No. 108736-35-2. Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. | |
OBP-801 Quick inquiry Where to buy Suppliers range | OBP-801, also known YM753 and spiruchostatin A, is a novel cyclic-peptide-based HDAC inhibitor. YM753 is a bacteria-derived natural product containing a disulfide bond. It potently inhibited HDAC enzyme with an IC50 of 2.0 nM in the presence of dithiothreitol. YM753 was rapidly converted to a reduced form in tumor cells, and then induced accumulation of acetylated histones, followed by p21WAF1/Cip1 expression, tumor cell growth inhibition and tumor-selective cell death. In an in vitro washout study, YM753 showed prolonged accumulation of acetylated histones in WiDr human colon carcinoma cells. In vivo YM753 dosing of mice harboring WiDr colon tumor xenografts significantly inhibited the tumor growth via sustained accumulation of acetylated histones in the tumor tissue. In a pharmacokinetic study, YM753 rapidly disappeared from the plasma, but its reduced form remained in the tumor tissue. Moreover, the accumulation of acetylated histones induced by YM753 was tumor tissue selective compared to several normal tissues. YM753 has attractive pharmacodynamic and pharmacokinetic properties giving it potential as an antitumor agent. Synonyms: OBP 801; OBP801; spiruchostatin A; YM-753; YM 753; (1S,5S,6R,9S,20R,E)-5-hydroxy-6-isopropyl-20-methyl-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetraone. Grades: >98%. CAS No. 328548-11-4. Molecular formula: C20H31N3O6S2. Mole weight: 473.60. | |
Pseudo RACK1 Quick inquiry Where to buy Suppliers range | Pseudo RACK1 is an activator of protein kinase C which is a family of protein kinase enzymes involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. Molecular formula: C144H225N43O34S3. Mole weight: 3198.81. |