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Product | Description | |
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10-[3-(2,2-Diimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxypropyl]-7,8-dimethyl-isoalloxazine Quick inquiry Where to buy Suppliers range | 10-[3-(2,2-Diimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxypropyl]-7,8-dimethyl-isoalloxazine is an intermediate uin the synthesis of Riboflavin 4',5'-Diphosphate which is a diphosphate derivative of Riboflavin (R414995); a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor). Group: Biochemicals. Grades: Highly Purified. CAS No. 22854-81-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C20H24N4O6. US Biological Life Sciences. | Worldwide |
10- ( ( (4R, 5R, 6S) -6- ( ( (tert-Butyldiphenylsilyl) oxy) methyl) -5-hydroxy-2, 2-dimethyl-1, 3-dioxan-4-yl) methyl) -7, 8-dimethylbenzo [g]pteridine-2, 4 (3H, 10H) -dione Quick inquiry Where to buy Suppliers range | 10- ( ( (4R, 5R, 6S) -6- ( ( (Tert-butyldiphenylsilyl) oxy) methyl) -5-hydroxy-2, 2-dimethyl-1, 3-dioxan-4-yl) methyl) -7, 8-dimethylbenzo [g]pteridine-2, 4 (3H, 10H) -dioneis an intermediate uin the synthesis of Riboflavin 4',5'-Diphosphate which is a diphosphate derivative of Riboflavin (R414995); a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C36H42N4O6Si, Molecular Weight: 654.83. US Biological Life Sciences. | Worldwide |
1-Deoxy-1-[ (3-hydroxymethyl-4-methyl-6- (2-phenyldiazenyl) phenyl) amino]-D-ribitol Quick inquiry Where to buy Suppliers range | 1-Deoxy-1-[ (3-hydroxymethyl-4-methyl-6- (2-phenyldiazenyl) phenyl) amino]-D-ribitol is an intermediate in the synthesis of 8-Hydroxymethyl Riboflavin which is an impurity of Riboflavin (R414995), a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H25N3O5. US Biological Life Sciences. | Worldwide |
1-Deoxy-1-[(3-hydroxymethyl-4-methylphenyl)amino]-D-ribitol Quick inquiry Where to buy Suppliers range | 1-Deoxy-1-[(3-hydroxymethyl-4-methylphenyl)amino]-D-ribitol is an intermediate in the synthesis of 8-Hydroxymethyl Riboflavin which is an impurity of Riboflavin (R414995), a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H21NO5. US Biological Life Sciences. | Worldwide |
(1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | (1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences. | Worldwide |
(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Quick inquiry Where to buy Suppliers range | (1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol is an intermediate used in the synthesis of ent-Abacavir, which is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. CAS No. 216481-88-8. Molecular formula: C11H12ClN5O. Mole weight: 265.7. | |
20(S)-Ginsenoside F1 Quick inquiry Where to buy Suppliers range | Ginsenoside F1 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to inhibit human cytochrome P450 enzymes. This has application in anti-cancer therapeutics as well as protective liver effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 53963-43-2. Pack Sizes: 10mg, 25 mg. Molecular Formula: C36H62O9. US Biological Life Sciences. | Worldwide |
2-(4-Thiazolyl)benzimidazole Quick inquiry Where to buy Suppliers range | 2-(4-Thiazolyl)benzimidazole. Uses: Systemic fungicide used for diseases of fruits and vegetables and for control of Dutch elm disease.Thiabendazole; a thiazolyl benzimidazole available for oral administration. It is active against most common intestinal nematodes. As a result of its larvicidal and ovicidal activity, it is effective in strongyloidiasis, trichinosis, visceral larva migrans and cutaneous larva migrans. It is well absorbed from the small intestine. Peak plasma levels are reached about 1-2 h after a single oral dose of the suspension. It is extensively metabolized in the liver to the 5-hydroxy derivative, which is inactive. Most of the drug is excreted within 24 h. About 90% is excreted in the urine, chiefly as glucuronide or sulfate conjugates; the remainder is passed in the feces. A wide range of unpleasant side effects occur, including nausea and other gastrointestinal upsets, fever and neurological effects. It has been largely replaced by the less toxic benzimidazole carbamates. Although active against Ascaris lumbricoides, E. vermicularis and hookworms, it should not be used as primary therapy for these infections.2-(4-Thiazolyl)benzimidazole (Mintezol) occurs as a whitecrystalline substance that is only slightly soluble in waterbut is soluble in strong mineral acids. Thiabendazole is abasic compound with a pKa of 4.7 that forms complexeswith metal ions.Thiabendazole inhibits the helminth-specific enzymefumarate reductase. It is not known whether metal ionsare involved or if the inhibition of the enzyme is related tothiabendazole's anthelmintic effect. Benzimidazole anthelminticdrugs such as thiabendazole and mebendazolealso arrest nematode cell division in metaphase by interferingwith microtubule assembly. They exhibit a highaffinity for tubulin, the precursor protein for microtubulesynthesis.Thiabendazole has broad-spectrum anthelmintic activity.It is used to treat enterobiasis, strongyloidiasis (threadworminfection), ascariasis, uncinariasis (hookworm infection), andtrichuriasis (whipworm infection). It has also been used torelieve symptoms associated with cutaneous larva migrans(creeping eruption) and the invasive phase of trichinosis. Inaddition to its use in human medicine, thiabendazole iswidely used in veterinary practice to control i | |
25-Hydroxy Vitamin D3 3,3-Aminopropyl Ether Quick inquiry Where to buy Suppliers range | Vitamin D3 analog. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5- (3-Aminopropoxy) -2- methyl enecyclohexylidene] ethylidene] octahydro- α , α , ε , 7a-tetra methyl -1H-indene-1-pentanol; (3 β,5Z,7E)-3-(3-Aminopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol; 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3. Grades: Highly Purified. CAS No. 163018-26-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
25-Hydroxy Vitamin D3 3-Sulfate Sodium Salt Quick inquiry Where to buy Suppliers range | 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days. Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol 3-(Hydrogen Sulfate) Sodium Salt; 25-Hydroxyvitamin D3 3-Sulfate Sodium Salt; 25-Hydroxyvitamin D3 3 β-Sulfate Sodium Salt; Calcifediol 3-Sulfate Sodium Salt. Grades: Purified. Pack Sizes: 2.5mg. Molecular Formula: C??H??NaO?S, Molecular Weight: 502.68. US Biological Life Sciences. | Worldwide |
2,6-Dichlorobenzonitrile Quick inquiry Where to buy Suppliers range | 2,6-Dichlorobenzonitrile (DCBN or dichlobenil) is a herbicide and is slightly toxic for humans. It is metabolized in the liver by the enzyme CYP2A6. Group: Biochemicals. Grades: Highly Purified. CAS No. 1194-65-6. Pack Sizes: 50g, 100g. Molecular Formula: C7H3Cl2N, Molecular Weight: 172.01. US Biological Life Sciences. | Worldwide |
2,6-Dichlorobenzonitrile-13C6 Quick inquiry Where to buy Suppliers range | 2,6-Dichlorobenzonitrile-13C6 is the isotope labelled analog of 2,6-Dichlorobenzonitrile (D431945); a herbicide that is slightly toxic for humans and is metabolized in the liver by the enzyme CYP2A6. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13C6H3Cl2N, Molecular Weight: 177.97. US Biological Life Sciences. | Worldwide |
2-C-(tert-Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-D-allono-1,4-lactone Quick inquiry Where to buy Suppliers range | 2-C-(tert-Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-D-allono-1,4-lactone, an intricate biomedical compound, demonstrates exceptional efficacy in the management of liver diseases and cancer. Its multifaceted mechanism of action encompasses unparalleled anti-inflammatory capabilities and targeted enzyme inhibition, crucial in impeding the advancement of diseases. Notably, this compound exhibits remarkable potential in suppressing the proliferation of malignant cells, thus holding significant promise in the innovative exploration of therapeutic approaches for diverse medical conditions. | |
2'-(R)-Hydroxy-2',3'-dihydroabacavir Dihydrochloride Quick inquiry Where to buy Suppliers range | 2'-(R)-Hydroxy-2',3'dihydroabacavir is the impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H20N6O2 2HCl, Molecular Weight: 304.357291999999. US Biological Life Sciences. | Worldwide |
3- (2-Pyridyldithio) propanoic Acid Quick inquiry Where to buy Suppliers range | Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis. Group: Biochemicals. Alternative Names: 2-Carboxyethyl 2-Pyridyl Disulfide. Grades: Highly Purified. CAS No. 68617-64-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
3-epi-25-Hydroxy Vitamin D3 Quick inquiry Where to buy Suppliers range | The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -Octahydro-4- [ (2Z) -2- [ (5R) -5-hydroxy-2- methyl enecyclohexylidene] ethylidene] - α , α , ε , 7a-tetra methyl -H-indene-1-pentanol; (3α,5Z,7E)-9,10-Seco-cholesta-5,7,10(19)-triene-3,25-diol; 3-epi-25-Hydroxyvitamin D3. Grades: Highly Purified. CAS No. 73809-05-9. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
3-Indoxyl Phosphate, P-Toluidine Salt Quick inquiry Where to buy Suppliers range | 3-Indoxyl Phosphate, P-Toluidine Salt, a fundamental compound extensively employed in biomedical research, serves as an indispensable substrate for enzymatic assays to assess alkaline phosphatase activity. Noteworthy in the investigation of ailments characterized by alkaline phosphatase dysregulation, including osteoporosis and liver diseases, this product assumes a pivotal role. As it is widely accessible, it emerges as an indispensable implement for both drug discovery endeavours and clinical diagnostics, propelling advancements in these domains. Synonyms: 3-Indoxyl phosphate p-toluidine salt; 4-Methylanilinium 1H-indol-3-yl hydrogen phosphate; 3-Indoxyl phosphate, p-toluidine salt; 1H-indol-3-yl hydrogen phosphate; (4-methylphenyl)azanium; I-6300; DTXSID50647383; AKOS030253232. CAS No. 31699-61-3. Molecular formula: C8H8NO4P.C7H9N. Mole weight: 320.28. | |
4-IPP Quick inquiry Where to buy Suppliers range | 4-IPP is a potent and cell-permeable macrophage migration inhibitory factor (MIF) antagonist. It covalently modifies MIF N-terminal proline. It inhibits MIF-associated liver enzyme activity in vivo and acts as a suicide substrate to inactivate MIF biological and catalytic functions. It also inhibits anchorage and migration independence of human lung adenocarcinoma cell lines in vitro. Synonyms: 4-IPP; 4 IPP; 4IPP; 4-Iodo-6-phenylpyrimidine. Grades: ≥99% by HPLC. CAS No. 41270-96-6. Molecular formula: C10H7IN2. Mole weight: 282.08. | |
4-Methylphenyl 3,4,6-tri-O-acetyl-2-O-benzyl-b-D-thiogalactopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylphenyl 3,4,6-tri-O-acetyl-2-O-benzyl-b-D-thiogalactopyranoside is an innovative and versatile compound, employed as a vital reactant for the research and development of promising enzyme inhibitors targeting grave maladies, including liver cancer and diabetes. Synonyms: [(2R,3S,4S,5R,6S)-3,4-diacetyloxy-6-(4-methylphenyl)sulfanyl-5-phenylmethoxyoxan-2-yl]methyl acetate; (2R,3S,4S,5R,6S)-2-(Acetoxymethyl)-5-(benzyloxy)-6-(p-tolylthio)tetrahydro-2H-pyran-3,4-diyl diacetate. CAS No. 189744-09-0. Molecular formula: C26H30O8S. Mole weight: 502.58. | |
4-Methylumbelliferyl b-D-glucuronide Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl b-D-glucuronide is a substrate widely used in the biomedical industry for the detection and measurement of glucuronidase activity. It serves as a fluorogenic probe to determine the presence and activity of glucuronidase enzymes, which are involved in the metabolism and clearance of drugs and xenobiotics. This compound plays a crucial role in studying drug metabolism, liver diseases and drug-drug interactions. | |
4-Nitrophenyl phosphate Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl phosphate is a crucial recompound utilized in the biomedical industry for the detection of alkaline phosphatase activity. It undergoes enzymatic hydrolysis by alkaline phosphatase, resulting in the release of a yellow compound that can be measured spectrophotometrically. This recompound finds applications in the research of various diseases, including liver diseases, bone disorders is and genetic abnormalities. Synonyms: PHOSPHORIC ACID MONO-(4-NITRO-PHENYL) ESTER. CAS No. 330-13-2. Molecular formula: C6H6NO6P. Mole weight: 219.09. | |
4-Nitrophenyl phosphate bis(cyclohexylammonium) salt Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl phosphate bis(cyclohexylammonium) salt, an invaluable compound utilized extensively in the biomedical field, serves as an exceptional substrate for the discernment of alkaline phosphatase activity within diverse biochemical assays. With its pivotal role in investigating enzyme kinetics, ascertaining liver and bone ailments, and exploring phosphatase-related disorders, this product assumes paramount significance. Moreover, it facilitates the advancement and assessment of therapeutic drugs that focus on ameliorating phosphatase-associated irregularities. CAS No. 52483-84-8. | |
4-Nitrophenyl phosphate bis(tris(hydroxymethyl)amino methane) Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl phosphate bis(tris(hydroxymethyl)amino methane) is an indispensable and highly significant recompound serving as a prominent substrate in enzyme-linked immunosorbent assays (ELISA) to precisely quantify and assess the alkaline phosphatase activity. Consequently, this exceptional compound assumes a pivotal function in research of diverse afflictions encompassing liver disorders, bone diseases and neoplasms. Synonyms: 4-Nitrophenyl phosphate bis(tris) salt. CAS No. 68189-42-4. Molecular formula: C6H6NO6P.2C4H11NO3. Mole weight: 461.36. | |
5-Bromo-4-chloro-3-indolyl b-D-glucuronide sodium salt trihydrate Quick inquiry Where to buy Suppliers range | 5-Bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt trihydrate is a valuable biochemical reagent widely used in the biomedical industry. It acts as a substrate for enzymes like β-glucuronidase, aiding in the detection and quantification of enzyme activity in various biological samples. This compound is especially helpful in studying drug metabolism, toxicity, and certain diseases such as liver disorders and cancer. Synonyms: X-Glucuronide trihydrate X-GlcA Na. CAS No. 370100-64-4. Molecular formula: C14H12BrClNNaO7.3H2O. Mole weight: 498.64. | |
6,8-Difluoro-4-methylumbelliferyl b-D-glucuronide Quick inquiry Where to buy Suppliers range | 6,8-Difluoro-4-methylumbelliferyl b-D-glucuronide is a vital recompound widely used in the biomedical industry for detecting glucuronidase activity. It serves as a highly sensitive substrate that reacting with the enzyme to produce a fluorescent signal. This compound enables the analysis of glucuronidase activity in various biological samples aiding in the research of diseases related to drug metabolism, liver function and lysosomal storage disorders. CAS No. 215868-36-3. Molecular formula: C16H14F2O9. Mole weight: 388.27. | |
Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Molecular formula: C33H46N6O10. Mole weight: 686.75. | |
Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine Quick inquiry Where to buy Suppliers range | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir USP Related Compound D; Abacavir EP Impurity B; Abacavir Impurities; Abacavir EP Impurity B. CAS No. 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. | |
Acaterin Quick inquiry Where to buy Suppliers range | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Synonyms: (2R)-4-[(1R)-1-hydroxyoctyl]-2-methyl-2H-furan-5-one; 3-(1-Hydroxyoctyl)-5-methyl-2(5H)-furanone. Grades: >98%. CAS No. 144398-20-9. Molecular formula: C13H22O3. Mole weight: 226.31. | |
Acifran Quick inquiry Where to buy Suppliers range | Acifran is a nicotinic acid receptor agonist with hypolipidemic effects, which shows higher potency than nicotinic acid and clofibrate. It is a potent and full agonist at the human orphan GPCR HM74A/GPR109A and GPR109B. It reduces circulating LDL-cholesterol and serum triglycerides in vivo without affecting liver enzymes or liver weight. Synonyms: AY 25712; AY-25712; AY25712; 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid; (±)-Acifran; Reductol. Grades: ≥99% by HPLC. CAS No. 72420-38-3. Molecular formula: C12H10O4. Mole weight: 218.21. | |
Alectinib Quick inquiry Where to buy Suppliers range | Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. Synonyms: CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802. Grades: ≥95%. CAS No. 1256580-46-7. Molecular formula: C30H34N4O2. Mole weight: 482.62. | |
a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt Quick inquiry Where to buy Suppliers range | A paramount constituent in the field of biomedicine, a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt serves as a pivotal factor in the production and analysis of enzymes related to carbohydrate metabolism. Its crucial role further extends to research on liver glycogen storage diseases, as well as in the treatment of select forms of malignancy. Indeed, this reagent proves itself to be a fundamental cornerstone in contemporary biomedical research. Synonyms: α-L-Fucose-1-phosphate (cyclohexylammonium salt); 6-Deoxy-α-L-Galactopyranose 1-(Dihydrogen Phosphate) Cyclohexanamine (1:2); α-L-Fucopyranose 1-(Dihydrogen Phosphate) Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl 1-Phosphate Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl Phosphate Di(cyclohexylammonium) Salt. Grades: ≥98%. CAS No. 24333-03-7. Molecular formula: C6H13O8P.2C6H13N. Mole weight: 442.48. | |
Amrinone Quick inquiry Where to buy Suppliers range | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Synonyms: Inamrinone; Wincoram; Inocor; Cordemcura; Win-40680; Win40680; 3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grades: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20. | |
Aniline β-D-Glucuronide Quick inquiry Where to buy Suppliers range | A metabolite of Aniline. Arylamines are predominantly conjugated by constitutive enzyme forms in the liver. Uses: A metabolite of aniline. arylamines are predominantly conjugated by constitutive enzyme forms in the liver. Synonyms: 1-Deoxy-1-(phenylamino)-β-D-glucopyranuronic Acid. CAS No. 92117-30-1. Molecular formula: C12H15NO6. Mole weight: 269.25. | |
Aprotinin Quick inquiry Where to buy Suppliers range | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. Synonyms: H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH; EC: 3.4.21.9; Iniprol; Trasylol; Trazinin; Zymofren; Riker 52G. Grades: >99%. CAS No. 9087-70-1. Molecular formula: C284H432N84O79S7. Mole weight: 6511.48. | |
Benazepril Quick inquiry Where to buy Suppliers range | Benazepril, an angiotensin converting enzyme inhibitor, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. It is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor upon cleavage of its ester group by the liver. Synonyms: 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-; (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid; 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, [S-(R*,R*)]-; Benapril; Briem; Cibacen; Cibacen WS; Cibacene; 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grades: >98%. CAS No. 86541-75-5. Molecular formula: C24H28N2O5. Mole weight: 424.49. | |
β-cyano-L-alanine Quick inquiry Where to buy Suppliers range | β-cyano-L-alanine is a reversible inhibitor of the H2S-synthesizing enzyme CSE. It blocks H2S synthesis in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. Synonyms: BCA; beta-cyano-L-alanine; 3-Cyano-L-alanine; L-3-Cyanoalanine. Grades: ≥ 98% (TLC). CAS No. 6232-19-5. Molecular formula: C4H6N2O2. Mole weight: 114.1. | |
Bifendate Quick inquiry Where to buy Suppliers range | Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage. Uses: Cytochrome p-450 enzyme inhibitors. Synonyms: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester; DDB; Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate; Dimethyl dicarboxylate Biphenyl; α-DDB. Grades: 97.0%~103.0%. CAS No. 73536-69-3. Molecular formula: C20H18O10. Mole weight: 418.36. | |
Calcifediol monohydrate Quick inquiry Where to buy Suppliers range | Calcifediol monohydrate is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase. It can be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Uses: Bone density conservation agents. Synonyms: 25-hydroxy Vitamin D3 monohydrate. Grades: >98%. CAS No. 63283-36-3. Molecular formula: C27H46O3. Mole weight: 418.65. | |
Camostat Mesylate Quick inquiry Where to buy Suppliers range | Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis. Uses: Trypsin inhibitors. Synonyms: 4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate; Camostat Mesilate; Camostat Mesylate; FOY 305; FOY-305; FOY305. Grades: >98%. CAS No. 59721-29-8. Molecular formula: C20H22N4O5.CH4O3S. Mole weight: 494.52. | |
Carfilzomib Quick inquiry Where to buy Suppliers range | Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent that is used in treatment of refractory multiple myeloma. Carfilzomib is associated with a low rate of serum enzyme elevations during treatment and has been implicated to rare instances of clinically apparent, acute liver injury some of which have been fatal. Uses: API. CAS No. 868540-17-4. Product ID: 10-101-326. | |
CAY10594 Quick inquiry Where to buy Suppliers range | Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. There are two mammalian isoforms of PLD, which are PLD1 and PLD2. CAY10594 is a potent phospholipase D2 inhibitor (PLD2), which also prevents the invasive migration of breast cancer cells. It ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis. Synonyms: CAY 10594; CAY-10594. Grades: ≥98%. CAS No. 1130067-34-3. Molecular formula: C26H28N4O2. Mole weight: 428.5. | |
CH-223191 Quick inquiry Where to buy Suppliers range | CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.CH223191 can prevent 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR. These inhibitory effects of CH-223191 prevented the expression of cytochrome P450 enzymes, target genes of the AhR. CH-223191, may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology. Synonyms: CH223191; CH-223191; CH 223191. Grades: >98%. CAS No. 301326-22-7. Molecular formula: C19H19N5O. Mole weight: 333.39. | |
Chlorotrianisene Quick inquiry Where to buy Suppliers range | Chlorotrianisene is a powerful synthetic, non-steroidal estrogenic compound which is metabolized by liver microsomal enzymes primarily to the mono-O-demethylated derivative. It binds to the estrogen receptor on various estrogen receptor bearing cells. It was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. It belongs triphenylethylene group. It was derived from estrobin (DBE) and is a relatively weak estrogen. It is a selective estrogen receptor modulator (SERM), with predominantly estrogenic but also antiestrogenic effects, and was arguably the first SERM to ever be introduced. It has been listed. Uses: Chlorotrianisene was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. Synonyms: 1, 1', 1''-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene); 1-[2-Chloro-1, 2-bis(4-methoxyphenyl)vinyl]-4-methoxybenzene; Chlortrianisestrol; Chlortrianizen; Khlortrianizen; Hormonisene; Anisene; Metace; Rianil; Tace; 1-[1-Chloro-2, 2-bis(4-methoxyphenyl)ethenyl]; Chlorotrianisene; Chlortrianisestrol; Chlortrianizen; Chlorotrianisine; Chlorestrolo; Chlorotrianizen; Khlortrianizen; Clorestrolo; Clorotrisin; Hormonisene; Anisene; Metace; Rianil; Tace. Grades: 95%. CAS No. 569-57-3. Molecular formula: C23H21ClO3. Mole weight: 380.87. | |
cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride Quick inquiry Where to buy Suppliers range | cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 267668-74-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C11H12ClN5O HCl, Molecular Weight: 265.7. US Biological Life Sciences. | Worldwide |
cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride Quick inquiry Where to buy Suppliers range | cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4S)-rel-4-(2-Amino-6-chloro-9H-purin-9-yl)2-cyclopentene-1-methanol Hydrochloride. CAS No. 267668-74-6. Molecular formula: C11H12ClN5O HCl. Mole weight: 265.7. | |
Cyanocobalamin (Vitamin B12) Quick inquiry Where to buy Suppliers range | Prototype of the family of naturally occurring cobalt coordination compounds knows as corrinoids. Analogs of vitamin B12 which differ only in the β-ligand of the cobalt are termed cobalamins. Synthesized almost exclusively by bacteria. Dietary sources include fish, meat, liver, and dairy products; plants have little or no cobalamins. Converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment. Group: Biochemicals. Alternative Names: 5,6-Dimethyl-1-(3-O-phosphono-α-D-ribofuranosyl)-1H-benzimidazole Monoester Cobinamide Cyanide Inner Salt; 5,6-Dimethylbenzimidazolyl Cyanocobamide; 5,6-Dimethylbenzimidazolyl-Co-cyanocobamide; Anacobin; Antipernicin; Apikobal; B-Twelve; B-Twelve Ora; Bedodeka; Bedoz; Behepan; Berubi; Berubigen; Dobetin; Docemine; Docibin; Poyamin; Rebramin; Redamina; Vitarubin; Vitral. Grades: Cell Culture Grade. CAS No. 68-19-9. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C63H88CoN14O14P, Molecular Weight: 1355.38. US Biological Life Sciences. | Worldwide |
D-Eritadenine Quick inquiry Where to buy Suppliers range | D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase. Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats. Uses: Enzyme inhibitors. Synonyms: (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; Eritadenine; Lentysine; Lentinacin. Grades: ≥95%. CAS No. 23918-98-1. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
D-Glucose-6-phosphate dipotassium salt trihydrate Quick inquiry Where to buy Suppliers range | D-Glucose-6-phosphate dipotassium salt trihydrate - a biochemical regularly applied in the biomedical sector. This extraordinary substrate advances NADPH production through enzyme facilitation, which partakes in paramount physiological activities such as cholesterol and fatty acid synthesis. Furthermore, D-Glucose-6-phosphate dipotassium salt trihydrate is pivotal in addressing multiple metabolic illnesses including malaria and liver disease. Its therapeutic value bolsters its placement as an integral constituent in numerous healthcare-related research endeavors. Synonyms: Dipotassium glucose-6-phosphate; D-Glucose-6-phosphate Dipotassium Salt. Grades: 98%. CAS No. 5996-17-8. Molecular formula: C6H11K2O9P. Mole weight: 336.32. | |
D-Glutamine tert-Butyl Ester Hydrochloride Quick inquiry Where to buy Suppliers range | D-Glutamine tert-Butyl Ester Hydrochloride is a protected form of D-Glutamine. D-Glutamine is an unnatural isomer of L-Glutamine that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells. Group: Biochemicals. Alternative Names: D-Glutamine 1,1-Dimethylethyl Ester Hydrochloride; (R)-2-Amino-4-carbamoylbutyric Acid tert-Butyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 422324-35-4. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C?H??ClN?O?, Molecular Weight: 238.71. US Biological Life Sciences. | Worldwide |
Diclofenac-acyl-beta-D-glucuronide Quick inquiry Where to buy Suppliers range | Diclofenac-acyl-beta-D-glucuronide is a vital metabolite in the biotransformation of diclofenac, an NSAID, undergoing formation predominantly via liver uridine 5'-diphospho-glucuronosyltransferase enzymes. Its participation in the metabolism and elimination of diclofenac profoundly influences its pharmacokinetics and therapeutic efficacy for studying diverse inflammatory conditions. Synonyms: 1-O-[2-[(2,6-Dichlorophenyl)amino]phenylacetyl]-b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 64118-81-6. Molecular formula: C20H19Cl2NO8. Mole weight: 472.27. | |
DL-Propargyl glycine hydrochloride Quick inquiry Where to buy Suppliers range | DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-γ-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value of 55 μM and abolishes the rise in plasma H2S in anaesthetized rats induced with hemorrhagic shock. Synonyms: PAG; 2-Aminopent-4-ynoic acid hydrochloride; AK323755; AK110719. Grades: ≥95%. CAS No. 16900-57-5. Molecular formula: C5H7NO2·HCl. Mole weight: 149.6. | |
DMBO (CCDC-272761) Quick inquiry Where to buy Suppliers range | An oxazine that appears to mimic the pyranosidic moiety of heparin sulfate, and is shown to interact directly with several growth factors and cytokines including VEGF, TNF-a and heparin-binding-EGF in a surface plasmon resonance assay. At concentrations of 10-80uM, this compound dose-dependently inhibits the proliferation of VEGF-expressing LM8G7 cells (IC50=13uM), and TNF-a-expressing OVSAHO cells (IC50=19uM). At 195uM, a 99% reduction in cell growth is observed in HB-EGF-expressing SKOV-3 cultures. This compound inhibits heparanase-mediated degradation of heparin sulfate in LM8G7 cells (IC50=65uM and 104-206uM, in an enzymatic and a cell based assay, respectively). At 0.5-5uM, it markedly prevents the migration and invasion of the same culture, in a dose-dependent manner. In addition, it completely suppresses liver metastatic nodules of osteosarcoma mice injected with LM8G7 cells at 0.5mg/kg without any signs of toxicity in vivo, and demonstrates a synergistic anti-tumor effect when Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Eniluracil Quick inquiry Where to buy Suppliers range | Eniluracil, also known as GW776 and GW776C85, is an orally active and irreversible inhibitor of dihydropyrimidine dehydrogenase. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU. Uses: Enzyme inhibitors. Synonyms: 5-ethynyluracil; 5-ethynylpyrimidine-2,4(1H,3H)-dione; 5-Ethynyl-2-hydroxypyrimidin-4(1H)-one; GW776; GW-776; GW 776. CAS No. 59989-18-3. Molecular formula: C6H4N2O2. Mole weight: 136.11. | |
ent-Abacavir Quick inquiry Where to buy Suppliers range | ent-Abacavir (Abacavir EP Impurity A) is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Uses: Anti-hiv agents. Synonyms: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir. Grades: 97%. CAS No. 136470-79-6. Molecular formula: C14H18N6O. Mole weight: 286.33. | |
Epoprostenol Sodium Quick inquiry Where to buy Suppliers range | Epoprostenol Sodium is the sodium salt form of epoprostenol, which is a synthetic prostacyclin. It has vasodilatory and anticoagulant activity. It is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It prevents the formation of platelet plugs and is an effective vasodilator. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase. It directly simulates prostaglandin receptors in arterial vascular smooth muscle, thereby causing vasodilatation. lt is also used for the treatment of pulmonary hypertension. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. It is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract. It was developed by GlaxoSmithKline and has been listed. Uses: Epoprostenol sodium has vasodilatory and anticoagulant activity. it prevents the formation of platelet plugs and is an effective vasodilator. lt is also used for the treatment of pulmonary hypertension. Synonyms: Prostacyclin Sodium Salt; (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Flolan. Grades: >99 %. CAS No. 61849-14-7. Molecular formula: C20H31O5Na. Mole weight: 374.45. | |
Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] TFA Quick inquiry Where to buy Suppliers range | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] TFA is a subunit of Elongation factor 1 that encodes an isomer of the α subunit of the elongation factor-1 complex, responsible for the enzymatic delivery of aminoacyl tRNAs to ribosomes. This subtype (α1) is expressed in the brain, placenta, lungs, liver, kidney, and pancreas, while another subtype (α2) is expressed in the brain, heart, and skeletal muscle. Synonyms: H-Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu-OH TFA; L-leucyl-L-alpha-glutamyl-L-alpha-aspartyl-glycyl-L-prolyl-L-lysyl-L-phenylalanyl-L-leucine trifluoroacetate salt; THF-γ2 trifluoroacetate salt; Thymic humoral factor-γ2 trifluoroacetate salt; Thymoctonan trifluoroacetate salt. Grades: ≥95%. Molecular formula: C45H68F3N9O15. Mole weight: 1032.07. | |
γ-(6-Aminohexyl)-ATP - ATTO-620 Quick inquiry Where to buy Suppliers range | γ-(6-Aminohexyl)-ATP, a fluorescent molecule with a myriad of biomedical applications, pervades the field of cellular activity imaging. Its robust employment as a tracer belies its hidden potential for delving into the intricate mechanisms of ATP-dependent enzymatic processes and investigative studies involving maladies that revolve around the malfunctions of ATP metabolism, such as neurodegenerative diseases, liver diseases, and cancer. The vibrant ATTO-620 fluorescent label, in conjunction with γ-(6-Aminohexyl)-ATP, enables unparalleled visualization in research and analysis. Synonyms: γ-(6-Aminohexyl)-adenosine-5'-triphosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3- ATTO 620 (free acid). Mole weight: 1099.35 (free acid). | |
gamma-L-Glutamyl-alpha-naphthylamide Quick inquiry Where to buy Suppliers range | Gamma-L-Glutamyl-alpha-naphthylamide, a widely used enzymatic substrate, serves as a crucial tool in the identification of gamma-glutamyl transferase (GGT) activity in diverse physiological and pathological scenarios. Converging evidence has linked elevated levels of GGT to several diseases, spanning from liver and pancreatic cancer to alcoholism and cholestasis. By exploiting Gamma-L-Glutamyl-alpha-naphthylamide as a probe, scholars have unraveled new facets of GGT-related biochemistry, paving the way to the development of innovative therapeutic interventions. CAS No. 81012-91-1. Molecular formula: C16H18N2O5. Mole weight: 318.32. | |
Histrelin Quick inquiry Where to buy Suppliers range | Histrelin is a gonadotropin releasing hormone (GnRH) agonist that is a potent inhibitor of production of testosterone (in men) and estrogen (in women) and is used predominantly to treat advanced prostate cancer. Histrelin is associated with a low rate of transient serum enzyme elevations during therapy, but has not been linked convincingly to cases of clinically apparent acute liver injury. Uses: Peptide Inhibitors. CAS No. 76712-82-8. Product ID: R1965. | |
Lauroyl coenzyme A Quick inquiry Where to buy Suppliers range | Lauroyl Coenzyme A, a vital biochemical compound, is widely employed in the biomedicine sector owing to its remarkable potential in boosting the efficacy of specific enzymes associated with fatty acid metabolism. Its outstanding properties hold potential in curbing a range of maladies such as fatty liver disease, obesity, and metabolic syndrome while also enhancing the energy production capacity of cells. Synonyms: n-Dodecanoyl coenzyme A. Grades: 92-98%. CAS No. 6244-92-4. Molecular formula: C33H58N7O17P3S. Mole weight: 949.84. | |
LBX192 Quick inquiry Where to buy Suppliers range | LBX192 is a Liver Targeted Glucokinase Activator. It can activate the GK enzyme in vitro at low nM concentrations and reduce glucose levels during an oral glucose tolerance test in normal as well as diabetic mice. Synonyms: LBX192; LBX 192; LBX-192; NVP-LBX192; NVP-LBX-192; NVP-LBX 192; (R)-3-cyclopentyl-N-(5-methoxythiazolo[5,4-b]pyridin-2-yl)-2-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)propanamide. Grades: 98%. CAS No. 866772-52-3. Molecular formula: C26H33N5O4S2. Mole weight: 543.70. | |
Lisinopril dihydrate Quick inquiry Where to buy Suppliers range | The hydrate form of Lisinopril. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor with a number of properties distinguish it from other ACE inhibitors: It is hydrophilic, has a long half-life and tissue penetration, and is not metabolized by the liver. Uses: Cardiotonic agents. Synonyms: (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline Dihydrate; MK-521; Acerbon; Alapril; Carace; Coric; Novatec; Prinil; Prinivil; Tensopril; Vivatec; Zestril. Grades: 98%. CAS No. 83915-83-7. Molecular formula: C21H35N3O7. Mole weight: 441.52. | |
N-Acetyl-S-[N- (2-phenylethyl) thiocarbamoyl]-L-cysteine (2-Acetyl amino-3-phene thyl thiocarbamoyl sulfanyl -propionic Acid) Quick inquiry Where to buy Suppliers range | An enzyme inhibitor of human liver microsome. Group: Biochemicals. Alternative Names: 2-Acetyl amino-3-phene thyl thiocarbamoyl sulfanyl -propionic Acid. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Nafenopin Quick inquiry Where to buy Suppliers range | Nafenopin is a hypolipidemic agent, a peroxisome proliferator, on the activities of rat liver glutathione-requiring enzymes and catalase in comparison to the action of phenobarbital. Uses: A hypolipidemic agent. Synonyms: 2-Methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid. Grades: ≥98%. CAS No. 3771-19-5. Molecular formula: C20H22O3. Mole weight: 310.39. | |
Niacin (Nicotinic acid) Quick inquiry Where to buy Suppliers range | Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: Nicotinic acid; Vitamin B3; 3-Pyridinecarboxylic Acid; 3-Carboxylpyridine; 3-Carboxypyridine; Akotin; Apelagrin; Niacin; Niacor; Niaspan; Nicacid; Pelonin; Vitamin B5; Wampocap; β-Pyridinecarboxylic Acid. Grades: Cell Culture Grade. CAS No. 59-67-6. Pack Sizes: 100g, 500g, 1Kg. Molecular Formula: C6H5NO2, Molecular Weight: 123.11. US Biological Life Sciences. | Worldwide |
Nicotinic Acid-13C6,d4 Quick inquiry Where to buy Suppliers range | Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-13C6,d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Nicotinic Acid, 99.5-100.5% USP Quick inquiry Where to buy Suppliers range | Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: Nicotinic acid; Vitamin B3; 3-Pyridinecarboxylic Acid; 3-Carboxylpyridine; 3-Carboxypyridine; Akotin; Apelagrin; Niacin; Niacor; Niaspan; Nicacid; Pelonin; Vitamin B5; Wampocap; β-Pyridinecarboxylic Acid. Grades: USP. CAS No. 59-67-6. Pack Sizes: 100g, 500g, 1Kg. US Biological Life Sciences. | Worldwide |
Nicotinic Acid-d1 Quick inquiry Where to buy Suppliers range | Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d1; 3-Carboxylpyridine-d1; 3-Carboxypyridine-d1; Akotin-d1; Apelagrin-d1; Niacin-d1; Niacor-d1; Niaspan-d1; Nicacid-d1; Pelonin-d1; Vitamin B3-d1; Vitamin B5-d1; Wampocap-d1; β-Pyridinecarboxylic Acid-d1. Grades: Highly Purified. CAS No. 116975-14-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Nicotinic Acid-d3 (major) Quick inquiry Where to buy Suppliers range | Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). A representative lot contains >20% d4. Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d3; 3-Carboxylpyridine-d3; 3-Carboxypyridine-d3; Akotin-d3; Apelagrin-d3; Niacin-d3; Niacor-d3; Niaspan-d3; Nicacid-d3; Pelonin-d3; Vitamin B3-d3; Vitamin B5-d3; Wampocap-d3; β-Pyridinecarboxylic Acid-d3. Grades: Highly Purified. CAS No. 861405-75-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Nicotinic Acid-d4 Quick inquiry Where to buy Suppliers range | Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d4. Grades: Highly Purified. CAS No. 66148-15-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |