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| Product | Description | |
|---|---|---|
| Eosin B | Eosin B (Acid Red 91) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 91. CAS No. 548-24-3. Pack Sizes: 5 g; 25 g. Product ID: HY-D1198. |  |
| Eosin B certified | Eosin B certified. Group: Biochemicals. Alternative Names: 4',5'-Dibromo-2',7'-dinitrofluorescein disodium salt; Saffrosine; CI 454. Grades: Highly Purified. CAS No. 548-24-3. Pack Sizes: 100g, 250g, 500g, 1kg. US Biological Life Sciences. |  Worldwide |
| Eosin B, Certified | Eosin B, Certified. Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin B (C.I. 45400) | 25g Pack Size. Group: Stains & Indicators. Formula: C20H6Br2N2Na2O9. CAS No. 548-24-3. Prepack ID 48164504-25g. Molecular Weight 624.06. See USA prepack pricing. |  |
| Eosin B, high purity biological stain | Dyeing wool, cotton, and paper. In histology as a stain for epithelia, muscular fibers, nuclei, etc. Group: Heterocyclic organic compound. Alternative Names: EOSIN RED; SAFFROSINE; Eosine BN; Eosine BA; CAESAR RED; SAFROSIN; Nophalin G; EOSIN B. CAS No. 548-24-3. Molecular formula: C20H6Br2N2Na2O9. Mole weight: 624. Appearance: red to purple crystalline powder. Purity: Disodium Salt. IUPACName: disodium 4,5-dibromo-2,7-dinitro-3-oxospiro[2-benzofuran-1,9-xanthene]-3,6-diolate. Catalog: ACM548243. |  |
| Eosin B, high purity biological stain | Eosin B, high purity biological stain. Uses: Dyeing wool, cotton, and paper. in histology as a stain for epithelia, muscular fibers, nuclei, etc. Group: Xanthene dyes. Alternative Names: EOSIN RED; SAFFROSINE; Eosine BN; Eosine BA; CAESAR RED; SAFROSIN; Nophalin G; EOSIN B. CAS No. 548-24-3. Product ID: disodium 4,5-dibromo-2,7-dinitro-3-oxospiro[2-benzofuran-1,9-xanthene]-3,6-diolate. Molecular formula: 624. Mole weight: C20H6Br2N2Na2O9. QGAYMQGSQUXCQO-UHFFFAOYSA-L. Disodium Salt. |  |
| Eosin Bluish, Laboratory Grade, 25 g | Notes: For freshwater teleosts; ready-to-use solution. Formula: C20H6Br2N2Na2O9. Formula Wt: 624. 09. Storage Code: Green; general chemical storage. Group: chem-category ph-indicators. Alternative Names: Eosin B. Grades: chem-grade laboratory. CAS No. 548-24-3. Product ID: 859500. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Eosin B Spirit Soluble | Eosin B Spirit Soluble. Group: Biochemicals. Grades: Reagent Grade. CAS No. 56360-46-4. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin y bis(tetrabutylammonium salt) | Heterocyclic Organic Compound. Alternative Names: Eosin Y bis(tetrabutylammonium salt), 123333-95-9. CAS No. 123333-95-9. Molecular formula: C52H78Br4N2O5. Mole weight: 1130.8. Purity: 0.96. IUPACName: 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate;tetrabutylazanium. Canonical SMILES: CCCC[N+] (CCCC) (CCCC)CCCC. CCCC[N+] (CCCC) (CCCC)CCCC. C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. Catalog: ACM123333959. | |
| Eosin Yellowish, 1% Solution, Laboratory Grade, 100 mL | Formula: C20H6Br4Na2O5. Formula Wt: 691. 8. Characteristic: Red-brown crystalline powder. Storage Code: Green; general chemical storage. Group: chem-category biological stains. Alternative Names: Eosin Y, acid red 87. Grades: chem-grade laboratory. CAS No. 17372-87-1. Product ID: 859632. -- SOLD FOR EDUCATIONAL USE ONLY -- | |
| 15-deoxy-Δ12,14-Prostaglandin D2 | 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2), a metabolite of PGD2 (HY-101988), is an agonist of prostaglandin receptor 2 (DP2). 15-deoxy-Δ12,14-Prostaglandin D2 binds to DP2 (Ki=50 nM) and induces eosinophil activation ( EC 50 =8 nM). 15-deoxy-Δ12,14-Prostaglandin D2 also stimulates the recruitment of steroid receptor coactivator-1 ( SRC-1 ) to peroxisome proliferator-activated receptor γ ( PPARγ ), inducing PPARγ-mediated transcription. 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is cytotoxic to L1210 murine leukemia cells ( IC 50 =0.3 μg/ml) and inhibits ADP-induced platelet aggregation ( IC 50 =320 ng/mL). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15-Deoxy-Δ12,14-PGD2. CAS No. 85235-11-6. Pack Sizes: 1 mg (2.99 mM * 1 mL in Methyl acetate). Product ID: HY-116028. | |
| 16:0 Lyso PE | 16:0 Lyso PE is a naturally occurring lysophospholipid. 16:0 Lyso PE inhibits the growth of L. donovani promastigotes. It has been used to degranulate human eosinophils. Synonyms: 16:0 LPE; 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; 1-Palmitoyl-2-hydroxy-sn-glycero-3-Phosphoethanolamine. Grades: ≥98%. CAS No. 53862-35-4. Molecular formula: C21H44NO7P. Mole weight: 453.55. |  |
| 5-Maleimido-eosin for fluorescence | 5-Maleimido-eosin for fluorescence. Group: Biochemicals. Grades: Highly Purified. CAS No. 150322-02-4. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| 7-Bromo Epinastine | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H1 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 3-Amino-7-bromo-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine; 7-Bromo-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine. Grades: > 95%. CAS No. 1217052-16-8. Molecular formula: C16H14BrN3. Mole weight: 328.21. | |
| 7-Chloro Epinastine Hydrochloride | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H2 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 7-Chloro-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine Hydrochloride. Grades: > 95%. CAS No. 80012-45-9. Molecular formula: C16H14ClN3.HCl. Mole weight: 319.82. | |
| 9-Oxo Epinastine HBr | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H3 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 3-Amino-1,13b-dihydro-9H-dibenz[c,f]imidazo[1,5-a]azepin-9-one. Grades: > 95%. CAS No. 745761-19-7. Molecular formula: C16H13N3O. HBr. Mole weight: 263.30 80.91. | |
| Acidic Mammalian Chitinase Inhibitor, Bisdionin F | A cell-permeable, competitive Acidic Mammalian Chitinase (AMCase) Inhibitor (IC50=0.92uM and Ki=0.42uM for hAMCase, and IC50=2.2uM for mAMCase, in vitro) that demonstrates 20-fold selectivity for hAMCase over hCHIT1. It is shown to decrease chitinase enzymatic activity (5mg/kg, i.p.) in the lungs of control PBS- and OVA-challenged mice. Furthermore, it attenuates lung chitinase activity, reduces eosinophil influx, and improves ventilatory function, in vivo, in a murine model of allergic inflammation. It also causes neutrophilia in the lungs of OVA-challenged mice. Group: Biochemicals. Alternative Names: AMCase Inhibitor, 3,7-dimethyl-1-(3-(3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl)-1H-purine-2,6(3H,7H)-dione. Grades: Highly Purified. CAS No. 917877-86-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AhR Agonist V, VAF347 | A cell-permeable pyrimidinylphenylamine compound that directly and reversibly targets aryl hydrocarbon receptor (AhR) with high-affinity, and induces AhR signaling. Reported to act as an immunomodulator with anti-inflammatory properties. Potently suppresses IgE secretion in B-cells with an IC50 of ~2nM, and inhibits dendritic cells-mediated T-cell proliferation and cytokine production. Further, decreases lung eosinophilia in B-cell-deficient mice, and allergic inflammation. Downregulates PU.1 transcription factor, and impairs human monocytes and Langerhans dendritic cells differentiation. Group: Biochemicals. Alternative Names: ((4-(3-Chloro-phenyl)-pyrimidin-2-yl)-(4-trifluoromethyl-phenyl)-amine). Grades: Highly Purified. CAS No. 574759-62-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?, Molecular Weight: 349.7. US Biological Life Sciences. | Worldwide |
| Amthamine dihydrobromide | Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and has no activity at H1 receptors. It decreases myogenic tone and induces vasodilation of cerebral arteries in vitro. It can be used in the suppression of the release of serotonin and H2 receptor-mediated eosinophil peroxidase (EPO). It has been used to study the effect of mast cells on T regulatory cell function. Synonyms: 5-(2-Aminoethyl)-4-methylthiazol-2-amine Dihydrobromide; A 4730 Dihydrobromide; 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide; 2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide. Grades: ≥99% by HPLC. CAS No. 142457-00-9. Molecular formula: C6H13N3SBr2. Mole weight: 319.06. | |
| AP4A | AP4A is a signal molecule for DNA replication in mammalian cells. AP4A is used as a primer for oligoadenylate synthesis catalyzed by interferon-inducible 2-5A synthetase. AP4A is an inhibitor of eosinophil-derived neurotoxin (EDN). Uses: Ap4a is an inhibitor of eosinophil-derived neurotoxin (edn). Synonyms: (AppppA); P1-(5'-Adenosyl) P4-(5'-adenosyl) tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 5542-28-9. Molecular formula: C20H28N10O19P4 (free acid). Mole weight: 836.39 (free acid). | |
| AS-35 | AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation. Uses: As-35 is used as an antiallergic drug. Synonyms: AS 35; AS35; AS-35; 3-(1H-Tetrazol-5-yl)-9-[[[2-propyl-3-hydroxy-4-(methylcarbonyl)phenyl]oxy]methyl]-4H-pyrido[1,2-a]pyrimidin-4-one;AS35;4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-;9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one. Grades: >98%. CAS No. 108427-72-1. Molecular formula: C21H20N6O4. Mole weight: 420.42. | |
| AZ11665362 | AZ11665362 is a potent CRTH2 antagonist. It blocks the migration of eosinophils and basophils, and the rapid mobilization of eosinophils from bone marrow. It might be useful for the treatment of allergic diseases. Uses: Az11665362 might be useful for the treatment of allergic diseases. Synonyms: AZ-11665362; AZ 11665362; AZ11665362; (2,5-Dimethyl-3-(8-methyl-4-quinolinyl)-1H-indol-1-yl)acetic acid. Grades: 98%. CAS No. 629645-40-5. Molecular formula: C22H20N2O2. Mole weight: 344.41. | |
| AZD1981 | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. Synonyms: AZD1981; AZD 1981; AZD-1981. Grades: 98%. CAS No. 802904-66-1. Molecular formula: C19H17ClN2O3S. Mole weight: 388.866. | |
| Azure II Eosinate | Azure II Eosinate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences. | Worldwide |
| Benralizumab | Benralizumab (MEDI-563) is an interleukin-5 receptor α ( IL-5Rα )-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-563; BIW-8405. CAS No. 1044511-01-4. Pack Sizes: 1 mg; 2 mg. Product ID: HY-P9923. | |
| Benralizumab (anti-IL5RA ) | Benralizumab (anti-IL5RA ) (MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )) is an interleukin-5 receptor α ( IL-5Rα )-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA ). CAS No. 1044511-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9923A. | |
| BMS639623 | BMS639623 is a CCR3 antagonist with picomolar inhibition potency against eosinophil chemotaxis. It may be used for the treatment of asthma. Uses: Bms639623 may be used for the treatment of asthma. Synonyms: BMS-639623; BMS 639623; Urea, N-((1R,2S)-3-((3S)-3-((4-fluorophenyl)methyl)-1-piperidinyl)-2-hydroxy-1-methylpropyl)-N'-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)-. Grades: 98%. CAS No. 675122-44-8. Molecular formula: C25H32FN7O2. Mole weight: 481.57. | |
| BMS 688521 | BMS 688521 is a small molecule antagonist of leukocyte function associated antigen-1 (LFA-1). It has provided proof-of-concept for LFA-1 as an immunological target. BMS 688521 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 2.5 and 78 nM in HUVEC adhesion and mouse specific adhesion assays respectively), which inhibits eosinophil accumulation in the lungs in a mouse allergic eosinophilic lung inflammation model. Synonyms: 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid; BMS-688521; BMS688521; SCHEMBL5392413. Grades: ≥98%. CAS No. 893397-44-9. Molecular formula: C26H19Cl2N5O4. Mole weight: 536.37. | |
| bromide peroxidase | Bromoperoxidases of red and brown marine algae (Rhodophyta and Phaeophyta) contain vanadate. They catalyse the bromination of a range of organic molecules such as sesquiterpenes, forming stable C-Br bonds. Bromoperoxidases also oxidize iodides. Group: Enzymes. Synonyms: bromoperoxidase; haloperoxidase (ambiguous); eosinophil peroxidase. Enzyme Commission Number: EC 1.11.1.18. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0499; bromide peroxidase; EC 1.11.1.18; bromoperoxidase; haloperoxidase (ambiguous); eosinophil peroxidase. Cat No: EXWM-0499. |  |
| Cendakimab | Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC 50 s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RPC 4046; ABT 308; CC-93538. CAS No. 2151032-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99496. | |
| Cetirizine | Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine. It is a racemic selective H1 receptor inverse agonist. It is used in cutaneous mastocytosis. It is used in the treatment of allergies, hay fever, angioedema, and urticaria. It crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. Uses: Cetirizine used in the treatment of allergies, hay fever, angioedema, and urticaria. it crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. it has also been shown to inhibit eosinophil chemotaxis and ltb4 release. Synonyms: Virlix;Cetirizina;Cetryn;2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid. Grades: 95%. CAS No. 83881-51-0. Molecular formula: C21H25ClN2O3. Mole weight: 388.89. | |
| Cyanosin | Heterocyclic Organic Compound. Alternative Names: Cyanosin, Acid red 92, Cyanosine, Eosine bluish, Eosine Blue, Cyanosin B, Eosin Blue, Phloxine P, Phloxin B, Food Red No. 104, Cyanosine WS, Water Pink 2, D & C Red no. 28, Daiwa Red 45, Cyanosin (acid dye), Magdala Red Technical, Japan Red 104, Orient Water Pink 2, Eosin 10 B, Food Red 104. CAS No. 12777-84-3. Molecular formula: C20H2O5Na2Cl4Br4. Mole weight: 829.64. Purity: 0.96. IUPACName: disodium;2,4,5,7-tetrabromo-4,5,6,7-tetrachloro-3-oxospiro[2-benzofuran-1,9-xanthene]-3,6-diolate. Canonical SMILES: C1=C2C (=C (C (=C1Br)[O-])Br)OC3=C (C (=C (C=C3C24C5=C (C (=C (C (=C5Cl)Cl)Cl)Cl)C (=O)O4)Br)[O-])Br. [Na+]. [Na+]. Catalog: ACM12777843. | |
| Dehydro Epinastine | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H6 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 9H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine. Grades: > 95%. Molecular formula: C16H13N3. Mole weight: 247.30. | |
| Dehydro Epinastine HCl | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H4 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 9H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine Hydrochloride. Grades: > 95%. CAS No. 141342-70-3. Molecular formula: C16H13N3.HCl. Mole weight: 283.76. | |
| [Des-Arg9]-Bradykinin | [Des-Arg9]-Bradykinin is a selective Bradykinin(B1) receptor agonist and increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine; 9-De-arg-bradykinin; 9-Des-arg-BK; Des-arg(9)-bradykinin; 9-de-L-Argininebradykinin; 1-8-Bradykinin. Grades: ≥95%. CAS No. 15958-92-6. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
| [Des-Arg9]-Bradykinin TFA | [Des-Arg9]-Bradykinin TFA is a selective Bradykinin(B1) receptor agonist and increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Synonyms: 1-8-Bradykinin, mono(trifluoroacetate) (salt); H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH.TFA; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine trifluoroacetic acid. Grades: ≥95%. CAS No. 199433-70-0. Molecular formula: C44H61N11O10.C2HF3O2. Mole weight: 1018.05. | |
| DP2 Antagonist I (CRTH2 Antagonist I, GPR44 Antagonist I, (4-Chloro-2- ( (2-methyl-5- (propylsulfonyl) phenyl) ethynyl) phenoxy) acetic Acid) | A cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 2.0 and 2.4nM against 1.5nM PGD2 for human & murine DP2 binding, respectively), exhibiting much reduced potency against DP1 (Ki = 1.58uM; IC50 = 10uM), PGE receptor EP2 (54% inhibition at 10uM), and little or no activity toward 49 other receptors and ion channels. Effectively inhibits PGD2-induced cellular activation (IC50 = 32 and 80nM, respectively, using CHO-CRTH2 or human whole blood) in vitro and is efficacious in alleviating airway eosinophil infiltration in OVA-sensitized mice (30mg/kg; p.o.) in vivo with good oral bioavailability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??ClO?S. US Biological Life Sciences. | Worldwide |
| DP2 Antagonist II (CRTH2 Antagonist II, GPR44 Antagonist II, (R)-(5-Chloro-1'-(5-chloro-2-fluorobenzyl)-2,2',5'-trioxospiro(indole-3,3?-pyrrolidin)-1(2H)-yl)acetic Acid) | The (R) enantiomer of a cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 5.3 and 5.0nM against human & murine DP2, respectively), exhibiting much reduced potency against a panel of more than 50 other receptors and ion channels. Effectively inhibits DP2-dependent chemotaxis of primary human eosinophils (IC50 = 100nM). Exhibits higher Caco-2 permeability than DP2 Antagonist I, but less oral bioavailability in mice. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??Cl?FN?O?. US Biological Life Sciences. | Worldwide |
| D(+)-Raffinose pentahydrate | D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA ( K d = 32 μM) and GtfC. D(+)-Raffinose pentahydrate reduces cyclic diguanylate (c-di-GMP) by increased activity of a c-di-GMP specific phosphodiesterase. D(+)-Raffinose pentahydrate interferes with GTF function. D(+)-Raffinose pentahydrate decreases IL-4 and IL-5 mRNA. D(+)-Raffinose pentahydrate exhibits biofilm-inhibitory activity against Pseudomonas aeruginosa and Streptococcus mutans and inhibits allergic airway eosinophilia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Raffinose pentahydrate. CAS No. 17629-30-0. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-N1938. | |
| Eosin 5-isothiocyanate | Eosin 5-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60520-47-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0805. | |
| Eosine-5-isothiocyanate | Eosine-5-isothiocyanate. Group: Biochemicals. Grades: Highly Purified. CAS No. 60520-47-0. Pack Sizes: 25mg, 50mg, 100mg, 200mg, 500mg. Molecular Formula: C21H7Br4NO5S. US Biological Life Sciences. | Worldwide |
| Eosin Y | Eosin Y (Acid Red 87 free base) is a soluble acid red dye molecule. Eosin Y has a wide application in organic synthesis as a photoredox catalyst [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 87 free base. CAS No. 15086-94-9. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-D0505. | |
| Eosin Y | Eosin Y. Group: Biochemicals. Alternative Names: Acid red 87; C.I. 45380. Grades: Highly Purified. CAS No. 17372-87-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C20H6Br4Na2O5. US Biological Life Sciences. | Worldwide |
| Eosin Y | Eosin Y. Synonyms: 2',4',5',7'-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43. CAS No. 15086-94-9. Pack Sizes: 5, 25 g in glass bottle. Product ID: CDC10-0151. Molecular formula: C20H8Br4O5. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Eosin Y; CDC10-0151; 15086-94-9; C20H8Br4O5; 2',4',5',7'-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43; MFCD00036189; 15086-94-9. Purity: ~99 %. Physical State: Powder. Solubility: ethanol: 1 mg/mL. Quality Level: 200. Storage: room temp. Boiling Point: 640.3±55.0 °C(Predicted). Melting Point: 300 °C. Density: 1.02 g/mL at 20 °C. |  |
| Eosin Y disodium salt, Certified ≥93% (Dye content) | Eosin Y disodium salt, Certified ≥93% (Dye content). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin Y disodium salt, dye content 85%, indicator | Anti Septic. Group: Acid dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Molecular formula: C20H6Br4Na2O5. Mole weight: 691.859g/mol. IUPACName: disodium;2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Canonical SMILES: C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. ECNumber: 241-409-6. Catalog: ACM17372871. | |
| Eosin Y disodium salt, dye content 85%, indicator | Eosin Y disodium salt, dye content 85%, indicator. Uses: Anti septic. Group: Xanthene dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Product ID: disodium; 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Molecular formula: 691.859g/mol. Mole weight: C20H6Br4Na2O5. C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. InChI=1S/C20H8Br4O5. 2Na/c21-11-5-9-13 (7-3-1-2-4-8 (7)20 (27)28)10-6-12 (22)17 (26)15 (24)19 (10)29-18 (9)14 (23)16 (11)25; ; /h1-6, 25H, (H, 27, 28); ; /q; 2*+1/p-2. SEACYXSIPDVVMV-UHFFFAOYSA-L. | |
| Eosin Y free acid ≥96% (Dye content) | Eosin Y free acid ≥96% (Dye content). Group: Biochemicals. Grades: Reagent Grade. CAS No. 15086-94-9. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin Y solution | Eosin Y solution. Synonyms: 2',4',5',7'-Tetrabromofluorescein disodium salt, Acid red 87, Eosin yellowish solution. CAS No. 17372-87-1. Pack Sizes: 500 mL in glass bottle. Product ID: CDC10-0152. Molecular formula: C20H6Br4Na2O5. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Eosin Y solution; CDC10-0152; 17372-87-1; C20H6Br4Na2O5; 2',4',5',7'-Tetrabromofluorescein disodium salt, Acid red 87, Eosin yellowish solution; MFCD00005040; 17372-87-1. Purity: 5 wt. % in H2O. Physical State: Liquid. Solubility: H2O: 0.1 g/mL, dark red. Quality Level: 100. Storage: room temp. Application: Eosin Y is suitable for use in hematoxylin and eosin (H&E) staining procedures for various tissue samples like lung nodule and kidney sections. Melting Point: >300°C. Density: 1.015 g/mL at 25 °C. Product Description: Eosin Y, also known as Eosin yellowish is a widely used xanthene dye. It is a counterstain that is used to distinguish between various connective tissue fibers & matrices, and the cytoplasm of different types of cells. Eosin in combination with hematoxylin is useful to demonstrate the general histological architecture of a tissue. | |
| Ethyl Eosin certified | Ethyl Eosin certified. Group: Biochemicals. Alternative Names: Solvent Red 45; CI 45386; 2',4',5',7'-Tetrabromoeosin ethyl ester potassium salt. Grades: Highly Purified. CAS No. 6359-3-5. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Ethyl Eosin, Certified (Solvent Red 45) | Ethyl Eosin, Certified (Solvent Red 45). Group: Biochemicals. Alternative Names: C.I. 45386. Grades: Certified Dye. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Fenoterol Hydrobromide | A β2-adrenergic agonist. Bronchodilator; tocolytic. Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema.[1] Fenoterol administration might be linked to liver damage.[2] It has anti-inflammatory effects on eosinophil function.[3] Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).[4]. Group: Biochemicals. Alternative Names: 2-(3,5-Dihydroxyphenyl)-2-hydroxy-2?-(4-hydroxyphenyl)-1?-methyldiethylamine hydrobromide; 5- [1-Hydroxy-2- [ [2- (4-hydroxyphenyl) -1-methylethyl] amino] ethyl] -1, 3-benzenediol Hydrobromide; 1- (3, 5-Dihydroxyphenyl) -2-[2- (3-p-hydroxyphenyl) propylamino]ethanol Hydrobromide; Airum; Berotec; Dosberotec; Fenoterol Bromide; Partusisten; Phenoterol Hydrobromide; Th 1165a. Grades: Highly Purified. CAS No. 1944-12-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??BrNO?, Molecular Weight: 384.26. US Biological Life Sciences. | Worldwide |
| Fevipiprant | Fevipipran is a reversible competitive CRTh2 antagonist with IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. Now it is in Phase III clinical trials for the treatment of asthma. Uses: Allergic asthma; atopic dermatitis. Synonyms: NVP-QAW039; NVP-QAW 039; NVP-QAW-039 QAW-039; QAW039; QAW 039; Fevipiprant; 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid. Grades: 98%. CAS No. 872365-14-5. Molecular formula: C19H17F3N2O4S. Mole weight: 426.41. | |
| Flunisolide | Flunisolide is a corticosteroid, which is an orally active glucocorticoid receptor activator with anti-inflammatory activity. Flunisolide can induce eosinophil apoptosis , and is used for the research of asthma or rhinitis, and inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3385-3-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1121. | |
| Fosinopril sodium salt | Fosinopril sodium salt. Group: Biochemicals. Alternative Names: (4S) -4-Cyclohexyl-1-[[ (R) -[ (1S) -2-methyl-1- (1-oxopropoxy) propoxy] (4-phenylbutyl) phosphinyl]acetyl]-L-proline sodium salt; Acecor; Eosinopril. Grades: Highly Purified. CAS No. 88889-14-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C30H45NNaO7P. US Biological Life Sciences. | Worldwide |
| Imetit dihydrobromide | Imetit dihydrobromide is a potent and high affinity agonist at histamine H3 and H4 receptors (Ki = 0.3 and 2.7 nM, respectively). It induces an eosinophil shape change (EC50 = 25 nM). Synonyms: 5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide. Grades: ≥98% by HPLC. CAS No. 32385-58-3. Molecular formula: C6H10N4S.2HBr. Mole weight: 332.06. | |
| Jenner Stain Certified | Jenner Stain Certified. Group: Biochemicals. Alternative Names: Eosin-Methylene blue. Grades: Highly Purified. CAS No. 62851-42-7. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| JNJ 10191584 maleate | The maleate salt form of JNJ 10191584, which has been found to be a selective histamine H4 receptor silent antagonist and could restrain mast cell and eosinophil chemotaxis in vitro. Synonyms: VUF6002; VUF 6002; VUF-6002; JNJ-10191584 maleate; JNJ 10191584 maleate; JNJ10191584 maleate; 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate. Grades: ≥99% by HPLC. CAS No. 869497-75-6. Molecular formula: C13H15ClN4O.C4H4O4. Mole weight: 394.81. | |
| Leishman's Stain | Heterocyclic Organic Compound. Alternative Names: LEISHMAN'S EOSINE METHYLENE BLUE;LEISHMAN'S EOSINE METHYLENE BLUE SOLUTION;LEISHMAN'S STAIN;LEISHMAN STAIN;LEISHMAN STAIN SOLUTION;METHYLENE BLUE-EOSIN LEISHMAN;EOSIN-POLYCHROME METHYLENE BLUE;EOSIN METHYLENE BLUE ACCORDING TO LEISHMAN. CAS No. 12627-53-1. Molecular formula: n.a. Appearance: powder. Purity: biological stain. Catalog: ACM12627531. | |
| Leishman Stain | Leishman Stain. Group: Biochemicals. Alternative Names: Eosin Methylene blue according to Leishman; Methylene blue-eosin Leishman. Grades: Highly Purified. CAS No. 12627-53-1. Pack Sizes: 100g. US Biological Life Sciences. | Worldwide |
| Lirentelimab | Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 ( SIGLEC8 ). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK002; Antolimab. CAS No. 2283348-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99371. | |
| LIT-927 | LIT-927 is an orally available neutraligand of CXCL12. It reduces eosinophil recruitment in a murine model of allergic airway hypereosinophilia, displaying anti-inflammatory effects. Synonyms: 4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one. CAS No. 2172879-52-4. Molecular formula: C17H13ClN2O3. Mole weight: 328.75. | |
| LY255283 | This active molecular is a competitive leukotriene B4 receptor antagonist and IC50 value is about 100 nM. LY 255283 is selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM. It also inhibits the binding of radiolabeled LTB4 to eosinophil membranes and IC50 value is 260 nM. LY255283 reduces airway obstruction in animal models of asthma. However, clinical trials for asthma had been discontinued. Uses: Asthma. Synonyms: LY 255283; LY255283; LY-255283; (1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone). Grades: 98%. CAS No. 117690-79-6. Molecular formula: C19H28N4O3. Mole weight: 360.45. | |
| LY 255283 | LY255283, a competitive leukotriene B4 receptor antagonist, is used in leukotriene receptor research along with other selective leukotriene receptor agonists and antagonist to identify and differentiate the physiological and cell signaling effects of the leukotriene B4 receptor on processes such as paclitaxel resistance in MCF-7/DOX breast cancer cells, monocyte-derived dendritic cell chemotaxis, and 5-lipoxygenase activity and interleukin-8 production in human neutrophils. LY255283 may be used to help verify that an observed process or cell event is leukotriene B4 receptor-dependent.Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years.1,2 The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100nM.3 LY255283 exhibits IC50 values of ~950nM and >10uM at human recombinant BLT2 and BLT1 receptors, respectively.4 LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10uM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260nM.1. Group: Biochemicals. Alternative Names: 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]-ethanone. Grades: Highly Purified. CAS No. 117690-79-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H28N4O3, Molecular Weight: 360.5. US Biological Life Sciences. | Worldwide |
| Lyn peptide inhibitor acetate | Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. It can be used for the study of asthma, allergic, and other eosinophilic disorders. Synonyms: stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2.CH3CO2H; N-stearoyl-L-tyrosyl-glycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparagyl-L-prolinamide acetic acid; N-(1-Oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolinamide acetate. Grades: ≥95%. CAS No. 2918771-52-3. Molecular formula: C117H188N30O26. Mole weight: 2430.98. | |
| Mepolizumab | Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 ( IL-5 ), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SB 240563. CAS No. 196078-29-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9945. | |
| Mepolizumab (anti-IL5) | Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 ( IL-5 ), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 196078-29-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9945A. | |
| Mometasone | Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 105102-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0629. | |
| Montelukast | Montelukast (MK0476 free base) is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT 1 ). Montelukast can be used for the reseach of asthma and liver injury. Montelukast also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast decreases eosinophil infiltration into the asthmatic airways. Montelukast can also be used for COVID-19 research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK0476 free base. CAS No. 158966-92-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13315A. | |
| Nα-Boc-L-tryptophan | Nα-Boc-L-tryptophan is an N-Boc-protected form of L-Tryptophan. L-Tryptophan is an essential amino acid that is important for cell proliferation and the biosynthesis of proteins. It is a precursor to Serotonin, a neurotransmitter that aids in sleep and mental state. L-Tryptophan is also thought to cause eosinophilia-myalgia syndrome. Synonyms: Boc-L-Trp-OH; N-[(tert-Butoxy)carbonyl]-L-tryptophan; N-(tert-Butoxycarbonyl)-L-tryptophan; (S)-2-((tert-Butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoic acid; (2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid; Nalpha-Boc-L-Tryptophane; N-Boc-L-tryptophan. Grades: ≥ 99% (HPLC). CAS No. 13139-14-5. Molecular formula: C16H20N2O4. Mole weight: 304.30. | |
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