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(±)-Epibatidine is a potent nicotinic agonist (Ki = 0.02 and 233 nM for α4β2 and α7 nicotinic receptors, respectively). Uses: Analgesic. Synonyms: Epibatidine; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane. CAS No. 140111-52-0. Molecular formula: C11H13ClN2. Mole weight: 208.69.
(±)-Epibatidine
High affinity nicotinic agonist (Ki values are 0.02 and 233 nM for α4β2 and α7 nicotinic receptors respectively). Analgesic. Uses: Analgesics, non-narcotic. Synonyms: (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane; 2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane. Grade: ≥99%. CAS No. 148152-66-3. Molecular formula: C11H13ClN2. Mole weight: 208.69.
(-)-Epibatidine dihydrochloride
(-)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (-)-Enantiomer of (±)-Epibatidine dihydrochloride. Synonyms: (3S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grade: 99%. CAS No. 152378-30-8. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
(+)-Epibatidine dihydrochloride
(+)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (+)-Enantiomer of (±)-Epibatidine dihydrochloride. Synonyms: 3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grade: 99%. CAS No. 166374-43-2. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
(±)-Epibatidine dihydrochloride
(±)-Epibatidine dihydrochloride is a highly potent nicotinic agonist used as a non-narcotic analgesic. Uses: Analgesic. Synonyms: (1R,3S,4S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grade: 99%. CAS No. 162885-01-0. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
A potent partial agonist selective for alpha7 nAChRs (EC50 = 34uM). Widely used in investigating the roles of alpha7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 501684-93-1. Pack Sizes: 5mg. Molecular Formula: C??H??ClN? 2HCl xH2O. US Biological Life Sciences.
2-Chloro-5-iodo-4-methylpyridine can be used as reactant/reagent of synthesis of conformationally constrained spirodi hydrofuropyridine analogs of epibatidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 550347-54-1. Pack Sizes: 500mg, 1g. Molecular Formula: C6H5ClIN, Molecular Weight: 253.47. US Biological Life Sciences.
Worldwide
AT 1001
AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor ( α3β4 nAChR ) ( K i =2.64 nM). AT 1001 reversibly blocks inward currents induced by Epibatidine (HY-101078) in HEK cells transfected with α3β4 nAChR. AT-1001 dose-dependently inhibits nicotine self-administration behavior in rats without affecting food-reinforced responding. AT 1001 can be utilized in the research of nicotine addiction and smoking cessation therapies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314801-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135783.
Epiboxidine hydrochloride
Epiboxidine is a potent nicotinic acetylcholine receptor agonist. An analog of epibatidine. Synonyms: exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane hydrochloride. CAS No. 188895-96-7. Molecular formula: C10H15ClN2O. Mole weight: 214.69.
Hemicholinium 3
Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a K i value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh) [1]. Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [ 3 H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hemicholinium dibromide. CAS No. 312-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B2152.
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