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| Product | Description | |
|---|---|---|
| Epothilone F | Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin. Synonyms: (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; epothilone F. Grade: >98%. CAS No. 208518-52-9. Molecular formula: C27H41NO7S. Mole weight: 523.69. |  |
| 1,4-Butanediol-13C4 | Isotope labelled 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 286012-95-1. Pack Sizes: 5mg, 10mg. Molecular Formula: 13C4H10O2. US Biological Life Sciences. |  Worldwide |
| 1,4-Butanediol-2,2,3,3-d4 | 1,4-Butanediol-2,2,3,3-d4 is the d4 labelled analogue of 1,4-Butanediol (B690005) which is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 38274-25-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C4H6D4O2, Molecular Weight: 94.15. US Biological Life Sciences. | Worldwide |
| 1,4-Butanediol-d8 | 1,4-Butanediol-d8 is the labelled d8 analogue of 1,4-Butanediol (B690005) which is a reagent used in organic synthesis including the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 74829-49-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C4H2D8O2. US Biological Life Sciences. | Worldwide |
| 1-Methyl-4- (tributylstannyl) imidazole | 1-Methyl-4- (tributylstannyl) imidazole is used as a reagent in the synthesis of methylthiopyrazole epothilone B which is a highly potent anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 446285-73-0. Pack Sizes: 500mg, 1g. Molecular Formula: C16H32N2Sn, Molecular Weight: 371.15. US Biological Life Sciences. | Worldwide |
| 4,5-Dihydro-2-methyl-4-thiazolecarboxylic Acid | 4,5-Dihydro-2-methyl-4-thiazolecarboxylic Acid, can be used as a chain-initiating methylthiazole ring in the synthesis of Epothilone derivatives. It can also be used for the synthesis of DL-cysteines. Synonyms: 2-Methyl-2-thiazoline-4-carboxylic Acid. Grade: > 95%. CAS No. 84184-18-9. Molecular formula: C5H7NO2S. Mole weight: 145.18. | |
| 4-Formyl-2-methoxyphenyl β-D-Glucopyranosiduronic Acid Triacetate Methyl Ester | Used in the preparation of epothilone-saccharide conjugates for the treatment of proliferative diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 704885-44-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Epothilon A | Epothilons A is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum. It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Synonyms: (-)-Epothilone A; Epo A; NSC-684362; (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione. Grade: >98%. CAS No. 152044-53-6. Molecular formula: C26H39NO6S. Mole weight: 493.65. | |
| Epothilon B | Epothilons B is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum, which is used as a microtubule stabilization agent (EC0.01 = 1.8 μM). It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Synonyms: Patupilone; (-)-Epothilone B. Grade: 98%. CAS No. 152044-54-7. Molecular formula: C27H41NO6S. Mole weight: 507.68. | |
| Epothilone A | Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A is under investigation as an antitumor agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-53-6. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Epothilone B | Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-54-7. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Epothilone B (synthetic) | Epothilone B (synthetic). Group: Biochemicals. Alternative Names: (1S, 3S, 7S, 10R, 11S, 12S, 16R)-7, 11-Dihydroxy-8, 8, 10, 12, 16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4, 17-dioxabicyclo[14. 1. 0]heptadecane-5, 9-dione; (-)-Epothilone B; EPO 906. Grades: Highly Purified. CAS No. 152044-54-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H41NO6S. US Biological Life Sciences. | Worldwide |
| Epothilone B (synthetic) (EpoB) | Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumors. Epothilone B is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division. Group: Biochemicals. Alternative Names: EpoB. Grades: Highly Purified. CAS No. 52044-54-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Epothilone C | Epothilone C is a novel microtubule inhibitor and acts as an antineoplastic agent. Epothilones are originally isolated from cellulose-degrading myxobacterium Sorangium cellulosum. Synonyms: (-)-Deoxyepothilone A; (-)-Desoxyepothilone A; Desoxyepothilone A. CAS No. 186692-73-9. Molecular formula: C26H39NO5S. Mole weight: 477.66. | |
| Epothilone D | Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility. Uses: Anti-neoplastic. Synonyms: (4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione; (-)-Desoxyepothilone B; (-)-Epothilone D; 12,13-Deoxyepothilone B; Desoxyepothilone B; Epo D; KOS 862; NSC 703147; Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-,(4S-(4R*,7S,8R*,9R*,1 3Z,16R*(E)))-; (3S,7S,14S,15S,16R)-3,15-Dihydroxy-2,2,10,14,16-pentamethyl-7-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-6-oxacyclohexadec-9-ene-1,5-dione. Grade: 98%. CAS No. 189453-10-9. Molecular formula: C27H41NO5S. Mole weight: 491.68. | |
| Epothilone D (synthetic) | Epothilone D (synthetic). Group: Biochemicals. Alternative Names: (4S, 7R, 8S, 9S, 13Z, 16S) -4, 8-Dihydroxy-5, 5, 7, 9, 13-pentamethyl-16- [ (1E) -1-methyl-2- (2-methyl-4-thiazolyl) ethenyl] oxacyclohexadec-13-ene-2, 6-dione; (-)-Desoxyepothilone B; (-)-Epothilone D. Grades: Highly Purified. CAS No. 189453-10-9. Pack Sizes: 1mg. Molecular Formula: C27H41NO5S. US Biological Life Sciences. | Worldwide |
| Ixabepilone | Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXABEPILONE;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,9,9-pentamethyl-14-[(E) -1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1.0]heptadecane-8,12-dione;Aza-epothilone B;Bms 247550-1;Ixempra;Ixempra kit;Unii-K27005np0a;Azi-epothilone B. Product Category: Inhibitors. Appearance: Solid. CAS No. 219989-84-1. Molecular formula: C27H42N2O5S. Mole weight: 506.7. Purity: 0.9984. Canonical SMILES: O=C([C@@H]([C@H]([C@H](CCC[C@]1(O[C@]1(C[C@H](N2)/C(C)=C/C3=CSC(C)=N3)[H])C)C)O)C)C(C)([C@H](CC2=O)O)C. Product ID: ACM219989841. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (?)-Epothilone A | from Sorangium cellulosum, >95% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
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