Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Erlotinib | Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC 50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC 50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer [1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-358774; NSC 718781; OSI-774. CAS No. 183321-74-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-50896. |  |
| Erlotinib Carboxylic Acid | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grades: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. |  |
| Erlotinib-d6 | Erlotinib-d 6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: CP-358774-d6; NSC 718781-d6; OSI-774-d6. CAS No. 1034651-23-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-50896S. | |
| Erlotinib-d6 hydrochloride | Erlotinib-d 6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: CP-358774-d6 hydrochloride; NSC 718781-d6 hydrochloride; OSI-774-d6 hydrochloride. CAS No. 1189953-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12008S. | |
| Erlotinib-d6, Hydrochloride Salt (N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt) | Source: Synthetic. Group: Biochemicals. Alternative Names: N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Erlotinib hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H24ClN3O4. CAS No. 183319-69-9. Prepack ID 82977875-1g. Molecular Weight 429.9. See USA prepack pricing. |  |
| Erlotinib hydrochloride | Erlotinib hydrochloride. CAS No. 183319-69-9. Product ID: 2-08248. Molecular formula: C22H23N3O4.HCl. Mole weight: 429.9. |  |
| Erlotinib Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: [6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, OSI 774, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride, Erlotinib hydrochloride, Tarceva, CP 358774. |  |
| Erlotinib Hydrochloride | Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC 50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride. CAS No. 183319-69-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-12008. | |
| Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231) | A free base form of the EGFR inhibitor Erlotinib Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
| Erlotinib (Hydrochloride) (Standard) | Erlotinib (Hydrochloride) (Standard) is the analytical standard of Erlotinib (Hydrochloride). This product is intended for research and analytical applications. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC 50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 183319-69-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12008R. | |
| Erlotinib Hydroxy Metabolite | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grades: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
| Erlotinib impurity 1 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grades: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
| Erlotinib Impurity 11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grades: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Erlotinib Impurity 12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grades: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
| Erlotinib Impurity 13 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile. Grades: > 95%. CAS No. 236750-65-5. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Erlotinib Impurity 14 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-Amino-4,5-bis(2-methoxyethoxy)benzamide. Grades: > 95%. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.31. | |
| Erlotinib Impurity 15 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: ethyl 2-amino-3,4-bis(2-methoxyethoxy)benzoate. Grades: > 95%. Molecular formula: C15H23NO6. Mole weight: 313.35. | |
| Erlotinib Impurity 16 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((7,8-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzonitrile. Grades: > 95%. Molecular formula: C22H23N3O6. Mole weight: 393.45. | |
| Erlotinib impurity 2 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-Chloro-6-(2-Chloroethoxy)-7-(2-Methoxyethoxy)-Quinazoline. Grades: > 95%. CAS No. 183322-19-2. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib Impurity 2 (4-Chloro-7-(2-Chloroethoxy)-6-(2-Methoxyethoxy)-Quinazoline) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-7-(2-chloroethoxy)-6-(2-methoxyethoxy)quinazoline. Grades: > 95%. CAS No. 183322-20-5. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib impurity 3 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2,4-dichloro-6,7-bis(2-methoxyethoxy)quinazoline. Grades: > 95%. Molecular formula: C14H16Cl2N2O4. Mole weight: 347.20. | |
| Erlotinib Impurity 34 | Erlotinib Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-vinylaniline. CAS No. 15411-43-5. Molecular formula: C8H9N. Mole weight: 119.16. Catalog: APB15411435. | |
| Erlotinib impurity 4 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzoic acid. Grades: > 95%. Molecular formula: C21H23N3O6. Mole weight: 413.43. | |
| Erlotinib Impurity 5 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-methoxyethoxy)-N-phenylquinazolin-4-amine. Grades: > 95%. Molecular formula: C20H25N3O4. Mole weight: 369.42. | |
| Erlotinib impurity, 6-(2-chloroethoxy)-7-(2-methoxyethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 7-(2-chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-Quinazolinamine. Grades: > 95%. CAS No. 183321-85-9. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6-(2-methoxyethoxy)-7-(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)quinazolin-4-amine. Grades: > 95%. CAS No. 183321-83-7. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6,7-bis(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-chloroethoxy)-N-(3-ethynylphenyl)quinazolin-4-amine. Grades: > 95%. CAS No. 183321-82-6. Molecular formula: C20H17Cl2N3O2. Mole weight: 402.28. | |
| Erlotinib Impurity 7 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride. Grades: > 95%. CAS No. 183322-17-0. Molecular formula: C15H23NO6 HCl. Mole weight: 349.81. | |
| Erlotinib Impurity 74 | Erlotinib Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,5-bis(2-methoxyethoxy)-2-nitrobenzoic acid. CAS No. 1001416-73-4. Molecular formula: C13H17NO8. Mole weight: 315.28. Catalog: APB1001416734. | |
| Erlotinib Impurity 76 | Erlotinib Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. CAS No. 1241475-15-9. Molecular formula: C16H25N3O5. Mole weight: 339.39. Catalog: APB1241475159. | |
| Erlotinib Impurity 8 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib; N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine. Grades: > 95%. CAS No. 328528-74-1. Molecular formula: C20H22BrN3O4. Mole weight: 448.32. | |
| Erlotinib Impurity 9 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N-(3-cyanophenyl)acetamide. Grades: > 95%. Molecular formula: C24H25N3O5. Mole weight: 435.48. | |
| Erlotinib Impurity F | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib-3-vinyl Hydrochloride; 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine Hydrochloride; N-(3-Ethenylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride. Grades: > 95%. CAS No. 1624294-38-7. Molecular formula: C22H25N3O4. Mole weight: 395.46. | |
| Erlotinib mesylate | Erlotinib is an EGFR inhibitor. The drug follows Iressa (gefitinib), which was the first drug of this type. Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. By inhibiting the ATP, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. Synonyms: Tarceva; CP-358774; CP 358774; CP358774; OSI-774; OSI 774; OSI774; NSC 718781; NSC718781; NSC-718781; R 1415; R1415; R-1415. Grades: >98%. CAS No. 248594-19-6. Molecular formula: C23H27N3O7S. Mole weight: 489.54. | |
| Erlotinib metabolite M11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]acetic Acid. Grades: > 95%. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.40. | |
| Erlotinib metabolite M12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline; 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol; 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. CAS No. 183321-84-8. Molecular formula: C20H19N3O4. Mole weight: 365.389. | |
| Erlotinib O-Desmethyl Metabolite Isomer | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grades: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grades: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. | |
| Erlotinib (Standard) | Erlotinib (Standard) is the analytical standard of Erlotinib. This product is intended for research and analytical applications. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC 50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC 50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer [1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 183321-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50896R. | |
| 4-Methyl Erlotinib Hydrochloride | 4-Methyl Erlotinib Hydrochloride is an impurity of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-[(3-Ethynyl-4-methyl)phenyl]-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride. CAS No. 1346601-52-2. Molecular formula: C23H25N3O4. Mole weight: 407.46. | |
| Desethynyl Erlotinib | Desethynyl Erlotinib is an impurity of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-Bis(2-methoxyethoxy)-N-phenyl4-quinazolinamine. CAS No. 1145671-52-8. Molecular formula: C20H23N3O4. Mole weight: 369.41. | |
| Desmethyl Erlotinib | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol. Grades: > 95%. CAS No. 183321-86-0. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
| Desmethyl Erlotinib | Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420 free base; CP-373420. CAS No. 183321-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256A. | |
| Desmethyl erlotinib acetate | Desmethyl erlotinib acetate. Group: Biochemicals. Alternative Names: 6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)quinazoline; 2- [ [4- [ (3-Ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol 1-acetate; 2- [ [4- [ (3-ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol acetate ester. Grades: Highly Purified. CAS No. 183320-15-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H23N3O5. US Biological Life Sciences. | Worldwide |
| Desmethyl Erlotinib Acetate (6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline) | Desmethyl Erlotinib derivative. Group: Biochemicals. Alternative Names: 6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desmethyl erlotinib carboxylate acid | Desmethyl erlotinib carboxylate acid. Group: Biochemicals. Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]. Grades: Highly Purified. CAS No. 882172-60-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H19N3O5. US Biological Life Sciences. | Worldwide |
| Desmethyl erlotinib carboxylate acid | Desmethyl erlotinib carboxylate acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]. Product Category: Heterocyclic Organic Compound. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.39. Product ID: ACM882172603. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Desmethyl Erlotinib Carboxylate Acid | Cas No. 1170354-84-3. | |
| Desmethyl Erlotinib, Free Base | A metabolite of Erlotinib, an anti cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; OSI-420; CP 373420. Grades: Highly Purified. CAS No. 183321-86-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desmethyl Erlotinib hydrochloride | Desmethyl Erlotinib hydrochloride (OSI-420) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420; CP-373420 hydrochloride. CAS No. 183320-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256. | |
| Didesmethyl Erlotinib | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Didesmethyl Erlotinib Hydrochloride Salt; 2,2'-[[4-[(3-Ethynylphenyl)amino]-6,7-quinazolinediyl]bis(oxy)]bis-ethanol Monohydrochloride. Grades: > 95%. CAS No. 183320-12-9. Molecular formula: C21H23N3O4. Mole weight: 381.44. | |
| Didesmethyl erlotinib hydrochloride salt | Didesmethyl erlotinib hydrochloride salt. Group: Biochemicals. Alternative Names: 2, 2'-[[4-[ (3-Ethynylphenyl)amino]-6, 7-quinazolinediyl]bis (oxy)]bis-ethanol monohydrochloride. Grades: Highly Purified. CAS No. 183320-12-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H20ClN3O4. US Biological Life Sciences. | Worldwide |
| OSI-420-d4, Free Base (Desmethyl Erlotinib-d4) | A labeled metabolite of Erlotinib , an anti-cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl-d4) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; CP 373420. Grades: Highly Purified. CAS No. 1216420-11-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol | 2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol is an impurtiy in the synthesis of Desmethyl Erlotinib which is a metabolite of Erlotinib (E625000), an anti cancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H13ClN2O4. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester is an intermediate in the synthesis of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 179688-27-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23NO6, Molecular Weight: 313.35. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6 Hydrochloride | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6, is an intermediate in the synthesis of Erlotinib-d6 Hydrochloride, labeled Erlotinib (E625000), an Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C15H18D6ClNO6, Molecular Weight: 355.84. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of erlotinib (e625008), a egfr-targeted drug in the treatment of non-small cell lung cancer. egfr small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile; 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile. Grades: > 95 %. CAS No. 950596-58-4. Molecular formula: C13H18N2O4. Mole weight: 266.29. | |
| 3-Ethynylaniline | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: Reagent in the preparation of a metabolite of erlotinib (e625000), which is a selective epidermal growth factor receptor (egfr)-tyrosine kinase inhibitor and an antineoplastic. Synonyms: 3-ethynylaniline. Grades: > 95 %. CAS No. 54060-30-9. Molecular formula: C8H7N. Mole weight: 117.15. | |
| 3-Ethynylaniline | Reagent in the preparation of a metabolite of Erlotinib. Group: Biochemicals. Alternative Names: (3-Ethynylphenyl)amine; (m-Aminophenyl)acetylene; 1-Amino-3-ethynylbenzene; 3-Acetylenylaniline-d4; 3-Amino-1-ethynylbenzene; 3-Ethynylaniline; 3-Ethynylbenzenamine; m-Ethynylaniline. Grades: Highly Purified. CAS No. 54060-30-9. Pack Sizes: 10mg, 100mg, 1g, 5g. Molecular Formula: C8H7N, Form: Brown Oil. US Biological Life Sciences. | Worldwide |
| 4-Chloro-6,7-(2-chloroethoxy)-quinazoline | An intermediate in the synthesis of erlotinib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline | 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline (Compound 11 and 15) is a building block and synthetic intermediate, which can be used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer agents. 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline can also be used to synthesize EGFR inhibitors, including Erlotinib (HY-50896), with antiproliferative activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183322-18-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-W007977. | |
| 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline | 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline;4-Chloro-6,7-(2-methoxyethoxy)quinazoline;4-Chloro-6,7-bis(2-methoxyethoxy)quinazolin;6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline;Erlotinib Intermediate 1;4-chloro-6,7-di(2-methoxyethoxy)quinazoline;CP-335963;PF-508367. Product Category: Heterocyclic Organic Compound. CAS No. 183322-18-1. Molecular formula: C14H17ClN2O4. Mole weight: 312.75. Purity: 0.98. Density: 1.257. Product ID: ACM183322181. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline; 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline. Grades: > 95 %. CAS No. 183322-18-1. Molecular formula: C14H17ClN2O4. Mole weight: 312.75. | |
| 6,7-bis(2-Methoxyethoxy)-3,4-dihydroquinazolin-4-one | An intermediate in the synthesis of erlotinib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4(3H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-; 4(1H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-; 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone; 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one; 6,7-Bis(2-methoxyethoxy)-quinazoline-4(3H)-one; 6,7-Di(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one; CP380736; CP 380736; CP-380736; PF-00520893; PF00520893; PF 00520893. Grades: ≥95%. CAS No. 179688-29-0. Molecular formula: C14H18N2O5. Mole weight: 294.30. | |
| ALW-II-41-27 | ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule inhibitor ALW-II-41-27 decreased both survival and proliferation of erlotinib-resistant tumor cells and inhibited tumor growth in vivo. ALW-II-41-27 was also effective in decreasing viability of cells with acquired resistance to the third-generation EGFR TKI AZD9291. Collectively, these data define a role for EPHA2 in the maintenance of cell survival of TKI-resistant, EGFR-mutant lung cancer and indicate that EPHA2 may serve as a useful therapeutic target in TKI-resistant tumors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.7. Purity: >98%. IUPACName: N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(thiophen-2-yl)nicotinamide. Canonical SMILES: O=C(NC1=CC(C(NC2=CC=C(CN3CCN(CC)CC3)C(C(F)(F)F)=C2)=O)=CC=C1C)C4=CN=CC(C5=CC=CS5)=C4. Product ID: ACM1186206790. Alfa Chemistry ISO 9001:2015 Certified. | |
| Angiogenesis related Compound Library | A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries. |  |
| CH5164840 | CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations. Synonyms: CH5164840; CH-5164840; CH 5164840. Grades: 98%. CAS No. 1052645-73-4. Molecular formula: C19H23N5O2S. Mole weight: 385.49. | |
| Debio 0932 | Debio 0932, also known as CUDC-305, is a novel Hsp90 inhibitor with strong affinity for Hsp90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents. Debio 0932 potently inhibits tumour growth in subcutaneous xenograft models of a number of solid and haematological malignancies, including models of NSCLC which harbour mutations conferring acquired or primary erlotinib resistance. Furthermore, Debio 0932 is able to extend animal survival in models of brain metastasis due to its ability to cross the blood-brain barrier, and it enhances the activity of several standard-of-care agents in animal models of cancer. Synonyms: Debio0932; Debio 0932; CUDC-305; CUDC305; CUDC 305. Grades: >98%. CAS No. 1061318-81-7. Molecular formula: C22H30N6O2S. Mole weight: 442.58. | |
Our database is helping our users find suppliers everyday.
