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Product | Description | |
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Erlotinib Carboxylic Acid Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grades: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. | |
Erlotinib-d6, Hydrochloride Salt (N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt) Quick inquiry Where to buy Suppliers range | Source: Synthetic. Group: Biochemicals. Alternative Names: N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Erlotinib hydrochloride Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H24ClN3O4. CAS No. 183319-69-9. Prepack ID 82977875-1g. Molecular Weight 429.9. See USA prepack pricing. | |
Erlotinib Hydrochloride Quick inquiry Where to buy Suppliers range | Erlotinib Hydrochloride. Group: Active Pharmaceutical Ingredients (APIs). Alternative Names: Tarceva. CAS No. 183319-69-9. Product ID: ACM183319699. Molecular formula: C22H24ClN3O4. Mole weight: 429.9. | |
Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231) Quick inquiry Where to buy Suppliers range | A free base form of the EGFR inhibitor Erlotinib Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
Erlotinib Hydroxy Metabolite Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grades: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
Erlotinib impurity 1 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grades: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
Erlotinib Impurity 11 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grades: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
Erlotinib Impurity 12 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grades: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
Erlotinib Impurity 13 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile. Grades: > 95%. CAS No. 236750-65-5. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
Erlotinib Impurity 14 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-Amino-4,5-bis(2-methoxyethoxy)benzamide. Grades: > 95%. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.31. | |
Erlotinib Impurity 15 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: ethyl 2-amino-3,4-bis(2-methoxyethoxy)benzoate. Grades: > 95%. Molecular formula: C15H23NO6. Mole weight: 313.35. | |
Erlotinib Impurity 16 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((7,8-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzonitrile. Grades: > 95%. Molecular formula: C22H23N3O6. Mole weight: 393.45. | |
Erlotinib impurity 2 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-Chloro-6-(2-Chloroethoxy)-7-(2-Methoxyethoxy)-Quinazoline. Grades: > 95%. CAS No. 183322-19-2. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
Erlotinib Impurity 2 (4-Chloro-7-(2-Chloroethoxy)-6-(2-Methoxyethoxy)-Quinazoline) Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-7-(2-chloroethoxy)-6-(2-methoxyethoxy)quinazoline. Grades: > 95%. CAS No. 183322-20-5. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
Erlotinib impurity 3 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2,4-dichloro-6,7-bis(2-methoxyethoxy)quinazoline. Grades: > 95%. Molecular formula: C14H16Cl2N2O4. Mole weight: 347.20. | |
Erlotinib impurity 4 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzoic acid. Grades: > 95%. Molecular formula: C21H23N3O6. Mole weight: 413.43. | |
Erlotinib Impurity 5 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-methoxyethoxy)-N-phenylquinazolin-4-amine. Grades: > 95%. Molecular formula: C20H25N3O4. Mole weight: 369.42. | |
Erlotinib impurity, 6-(2-chloroethoxy)-7-(2-methoxyethoxy) Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 7-(2-chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-Quinazolinamine. Grades: > 95%. CAS No. 183321-85-9. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
Erlotinib impurity, 6-(2-methoxyethoxy)-7-(2-chloroethoxy) Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)quinazolin-4-amine. Grades: > 95%. CAS No. 183321-83-7. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
Erlotinib impurity, 6,7-bis(2-chloroethoxy) Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-chloroethoxy)-N-(3-ethynylphenyl)quinazolin-4-amine. Grades: > 95%. CAS No. 183321-82-6. Molecular formula: C20H17Cl2N3O2. Mole weight: 402.28. | |
Erlotinib Impurity 7 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride. Grades: > 95%. CAS No. 183322-17-0. Molecular formula: C15H23NO6 HCl. Mole weight: 349.81. | |
Erlotinib Impurity 8 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib; N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine. Grades: > 95%. CAS No. 328528-74-1. Molecular formula: C20H22BrN3O4. Mole weight: 448.32. | |
Erlotinib Impurity 9 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N-(3-cyanophenyl)acetamide. Grades: > 95%. Molecular formula: C24H25N3O5. Mole weight: 435.48. | |
Erlotinib Impurity F Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib-3-vinyl Hydrochloride; 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine Hydrochloride; N-(3-Ethenylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride. Grades: > 95%. CAS No. 1624294-38-7. Molecular formula: C22H25N3O4. Mole weight: 395.46. | |
Erlotinib mesylate Quick inquiry Where to buy Suppliers range | Erlotinib is an EGFR inhibitor. The drug follows Iressa (gefitinib), which was the first drug of this type. Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. By inhibiting the ATP, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. Synonyms: Tarceva; CP-358774; CP 358774; CP358774; OSI-774; OSI 774; OSI774; NSC 718781; NSC718781; NSC-718781; R 1415; R1415; R-1415. Grades: >98%. CAS No. 248594-19-6. Molecular formula: C23H27N3O7S. Mole weight: 489.54. | |
Erlotinib metabolite M11 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]acetic Acid. Grades: > 95%. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.40. | |
Erlotinib metabolite M12 Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline; 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol; 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. CAS No. 183321-84-8. Molecular formula: C20H19N3O4. Mole weight: 365.389. | |
Erlotinib O-Desmethyl Metabolite Isomer Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grades: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl Quick inquiry Where to buy Suppliers range | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grades: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. | |
4-Methyl Erlotinib Hydrochloride Quick inquiry Where to buy Suppliers range | 4-Methyl Erlotinib Hydrochloride is an impurity of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-[(3-Ethynyl-4-methyl)phenyl]-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride. CAS No. 1346601-52-2. Molecular formula: C23H25N3O4. Mole weight: 407.46. | |
Desethynyl Erlotinib Quick inquiry Where to buy Suppliers range | Desethynyl Erlotinib is an impurity of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-Bis(2-methoxyethoxy)-N-phenyl4-quinazolinamine. CAS No. 1145671-52-8. Molecular formula: C20H23N3O4. Mole weight: 369.41. | |
Desmethyl Erlotinib Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol. Grades: > 95%. CAS No. 183321-86-0. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
Desmethyl erlotinib acetate Quick inquiry Where to buy Suppliers range | Desmethyl erlotinib acetate. Group: Biochemicals. Alternative Names: 6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)quinazoline; 2- [ [4- [ (3-Ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol 1-acetate; 2- [ [4- [ (3-ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol acetate ester. Grades: Highly Purified. CAS No. 183320-15-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H23N3O5. US Biological Life Sciences. | Worldwide |
Desmethyl Erlotinib Acetate (6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline) Quick inquiry Where to buy Suppliers range | Desmethyl Erlotinib derivative. Group: Biochemicals. Alternative Names: 6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Desmethyl erlotinib carboxylate acid Quick inquiry Where to buy Suppliers range | Desmethyl erlotinib carboxylate acid. Group: Biochemicals. Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]. Grades: Highly Purified. CAS No. 882172-60-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H19N3O5. US Biological Life Sciences. | Worldwide |
Desmethyl Erlotinib Carboxylate Acid Quick inquiry Where to buy Suppliers range | Cas No. 1170354-84-3. | |
Desmethyl Erlotinib, Free Base Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib, an anti cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; OSI-420; CP 373420. Grades: Highly Purified. CAS No. 183321-86-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Didesmethyl Erlotinib Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Didesmethyl Erlotinib Hydrochloride Salt; 2,2'-[[4-[(3-Ethynylphenyl)amino]-6,7-quinazolinediyl]bis(oxy)]bis-ethanol Monohydrochloride. Grades: > 95%. CAS No. 183320-12-9. Molecular formula: C21H23N3O4. Mole weight: 381.44. | |
Didesmethyl erlotinib hydrochloride salt Quick inquiry Where to buy Suppliers range | Didesmethyl erlotinib hydrochloride salt. Group: Biochemicals. Alternative Names: 2, 2'-[[4-[ (3-Ethynylphenyl)amino]-6, 7-quinazolinediyl]bis (oxy)]bis-ethanol monohydrochloride. Grades: Highly Purified. CAS No. 183320-12-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H20ClN3O4. US Biological Life Sciences. | Worldwide |
N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride Quick inquiry Where to buy Suppliers range | N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: N-(3-Desethynylphenyl)-N-(3-bromophenyl)erlotinib hydrochloride, Erlotinib impurity 3 hydrochloride, N-(3-Bromophenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride, N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib hydrochloride, N-(3-Bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride,4-Quinazolinamine, N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1). CAS No. 2055840-41-8. IUPAC Name: N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine;hydrochloride. Molecular formula: C20H22BrN3O4.ClH. Mole weight: 484.77. Catalog: APS2055840418. SMILES: Cl. COCCOc1cc2ncnc (Nc3cccc (Br)c3)c2cc1OCCOC. Format: Neat. | |
OSI-420-d4, Free Base (Desmethyl Erlotinib-d4) Quick inquiry Where to buy Suppliers range | A labeled metabolite of Erlotinib , an anti-cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl-d4) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; CP 373420. Grades: Highly Purified. CAS No. 1216420-11-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol Quick inquiry Where to buy Suppliers range | 2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol is an impurtiy in the synthesis of Desmethyl Erlotinib which is a metabolite of Erlotinib (E625000), an anti cancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H13ClN2O4. US Biological Life Sciences. | Worldwide |
2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester is an intermediate in the synthesis of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 179688-27-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23NO6, Molecular Weight: 313.35. US Biological Life Sciences. | Worldwide |
2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6 Hydrochloride Quick inquiry Where to buy Suppliers range | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester-d6, is an intermediate in the synthesis of Erlotinib-d6 Hydrochloride, labeled Erlotinib (E625000), an Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C15H18D6ClNO6, Molecular Weight: 355.84. US Biological Life Sciences. | Worldwide |
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of erlotinib (e625008), a egfr-targeted drug in the treatment of non-small cell lung cancer. egfr small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile; 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile. Grades: > 95 %. CAS No. 950596-58-4. Molecular formula: C13H18N2O4. Mole weight: 266.29. | |
3-Ethynylaniline Quick inquiry Where to buy Suppliers range | Reagent in the preparation of a metabolite of Erlotinib. Group: Biochemicals. Alternative Names: (3-Ethynylphenyl)amine; (m-Aminophenyl)acetylene; 1-Amino-3-ethynylbenzene; 3-Acetylenylaniline-d4; 3-Amino-1-ethynylbenzene; 3-Ethynylaniline; 3-Ethynylbenzenamine; m-Ethynylaniline. Grades: Highly Purified. CAS No. 54060-30-9. Pack Sizes: 10mg, 100mg, 1g, 5g. Molecular Formula: C8H7N, Form: Brown Oil. US Biological Life Sciences. | Worldwide |
3-Ethynylaniline Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: Reagent in the preparation of a metabolite of erlotinib (e625000), which is a selective epidermal growth factor receptor (egfr)-tyrosine kinase inhibitor and an antineoplastic. Synonyms: 3-ethynylaniline. Grades: > 95 %. CAS No. 54060-30-9. Molecular formula: C8H7N. Mole weight: 117.15. | |
4-Chloro-6,7-(2-chloroethoxy)-quinazoline Quick inquiry Where to buy Suppliers range | An intermediate in the synthesis of erlotinib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline Quick inquiry Where to buy Suppliers range | 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline. Group: Heterocyclic Organic Compound. Alternative Names: 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline;4-Chloro-6,7-(2-methoxyethoxy)quinazoline;4-Chloro-6,7-bis(2-methoxyethoxy)quinazolin;6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline;Erlotinib Intermediate 1;4-chloro-6,7-di(2-methoxyethoxy)quinazoline;CP-335963;PF-508367. Grades: 98%. CAS No. 183322-18-1. Molecular formula: C14H17ClN2O4. Mole weight: 312.75. Symbol: GHS05,GHS07. Melting Point: 105-107 °C. Density: 1.257. Safty Description: 26-39. Hazard statements: Xn. Supplemental Hazard Statements: H302-H318. | |
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline; 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline. Grades: > 95 %. CAS No. 183322-18-1. Molecular formula: C14H17ClN2O4. Mole weight: 312.75. | |
4-CHLORO-6,7-BIS-(2-METHOXY-ETHOXY)-QUINAZOLINE Quick inquiry Where to buy Suppliers range | 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline, 183322-18-1, Quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy)-, CP-335963, MFCD09751265, K44UPE46KJ, 4-Chloro-6,7-(2-methoxyethoxy)-quinazoline, 4-Chloro-6,7-bis-(2-methoxy-ethoxy)-quinazoline, 4-chloro-6,7-bis-(2-methoxyethoxy)quinazoline, PF-508367, 4-Chloro-6,7-(2-methoxyethoxy)quinazoline, Erlotinib Chloro Impurity, UNII-K44UPE46KJ, DI-N-OCTADECYLPHOSPHATE, SCHEMBL163465, DTXSID70461407, HMS3263I16, BCP26354, Tox21_501087, AKOS015851220, AC-6915, CCG-222391, CS-W007977, GS-4328, SB67325, NCGC00261772-01, SY017617, AM20090620, C2774, FT-0650149, 4-chloro-6,7-bis(2-methoxyethoxy) quinazoline, 4-chloro-6,7-di-(2-methoxyethoxy)quinazoline, 4-chloro-6,7-bis (2-methoxyethoxy) quinazoline, 4-chloro-6,7-bis (2-methoxyethoxy)-quinazoline, 4-chloro-6,7-bis-(2-methoxyethoxy)-quinazoline, 4-chloro-6,7-di-(2-methoxyethoxy) quinazoline, CP-335963, >=98% (HPLC), (6,7-bis(2-methoxyethoxy))-4-chloro-quinazoline, A812768, Q-101338. | |
6,7-bis(2-Methoxyethoxy)-3,4-dihydroquinazolin-4-one Quick inquiry Where to buy Suppliers range | An intermediate in the synthesis of erlotinib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4(3H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-; 4(1H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-; 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone; 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one; 6,7-Bis(2-methoxyethoxy)-quinazoline-4(3H)-one; 6,7-Di(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one; CP380736; CP 380736; CP-380736; PF-00520893; PF00520893; PF 00520893. Grades: ≥95%. CAS No. 179688-29-0. Molecular formula: C14H18N2O5. Mole weight: 294.30. | |
Angiogenesis related Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries. | |
CH5164840 Quick inquiry Where to buy Suppliers range | CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations. Synonyms: CH5164840; CH-5164840; CH 5164840. Grades: 98%. CAS No. 1052645-73-4. Molecular formula: C19H23N5O2S. Mole weight: 385.49. | |
Debio 0932 Quick inquiry Where to buy Suppliers range | Debio 0932, also known as CUDC-305, is a novel Hsp90 inhibitor with strong affinity for Hsp90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents. Debio 0932 potently inhibits tumour growth in subcutaneous xenograft models of a number of solid and haematological malignancies, including models of NSCLC which harbour mutations conferring acquired or primary erlotinib resistance. Furthermore, Debio 0932 is able to extend animal survival in models of brain metastasis due to its ability to cross the blood-brain barrier, and it enhances the activity of several standard-of-care agents in animal models of cancer. Synonyms: Debio0932; Debio 0932; CUDC-305; CUDC305; CUDC 305. Grades: >98%. CAS No. 1061318-81-7. Molecular formula: C22H30N6O2S. Mole weight: 442.58. | |
Ethyl 3,4-Bis(2-methoxyethoxy)benzoate Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: 3,4-bis(2-methoxyethoxy)benzoic acid ethyl ester is a compound used in the synthesis of erlotinib (e625008), a cancer treatment medicine. Synonyms: 3,4-bis(2-methoxyethoxy)benzoic acid ethyl ester; ethyl 3,4-bis(2-methoxyethoxy)benzoate. Grades: > 95 %. CAS No. 183322-16-9. Molecular formula: C15H22O6. Mole weight: 298.33. | |
Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate Quick inquiry Where to buy Suppliers range | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. it is also used to prepare erlotinib hydrochloride (e625000), a useful drug in treatment of non-small-cell lung cancer. Synonyms: 4,5-bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester; ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate. Grades: > 95 %. CAS No. 179688-26-7. Molecular formula: C15H21NO8. Mole weight: 343.33. | |
Gefitinib, Free Base (Iressa) Quick inquiry Where to buy Suppliers range | EGFR tyrosine kinase inhibitor that binds to the ATP-binding site of the enzyme. The functions of the EGFR tyrosine kinase in activating the Ras signal transduction cascade and malignant cell growth are thus inhibited. It has been shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating anti-apoptotic pathways in gefitinib-sensitive non-small cell lung cancers. These mutations tend to increase sensitivity to tyrosine kinase inhibitors including gefitinib and erlotinib. The adenocarcinoma subset of non-small cell lung cancer histologies often have these mutations, which are commonly found in Asians, women, and non-smokers. Group: Biochemicals. Grades: Highly Purified. CAS No. 184475-35-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
N- (3-Ethynylphenyl) [6, 7-bis (2-methoxyethoxy) quinazolin-4-yl]amine; 4-[ (3-Ethynylphenyl) amino]-6, 7-bis (2-methoxyethoxy) quinazoline Quick inquiry Where to buy Suppliers range | N- (3-Ethynylphenyl) [6, 7-bis (2-methoxyethoxy) quinazolin-4-yl]amine; 4-[ (3-Ethynylphenyl) amino]-6, 7-bis (2-methoxyethoxy) quinazoline. Group: Biochemicals. Alternative Names: N- (3-Ethynylphenyl) [6, 7-bis (2-methoxyethoxy) quinazolin-4-yl]amine; 4-[ (3-Ethynylphenyl) amino]-6, 7-bis (2-methoxyethoxy) quinazoline; Tarceva; Erlotinib. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C22H23N3O4. US Biological Life Sciences. | Worldwide |
OSI-413 Quick inquiry Where to buy Suppliers range | OSI-413 is an impurity of Erlotinib, a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Synonyms: OSI 413; OSI413; 7-(2'-Desmethyl) Erlotinib. Grades: >97%. CAS No. 183365-34-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.87. | |
PF-4989216 Quick inquiry Where to buy Suppliers range | PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently leads to inhibition in cell proliferation and xenograft tumor growth in NSCLCs harboring a PIK3CA mutation, including an erlotinib resistant line, NCI-H1975. Although PF-4989216 inhibits the phosphorylation of PI3K downstream molecules in the NSCLCs with PTEN loss (NCI-H1650), PF-4989216 does not sufficiently induce anti-tumor efficacy in NCI-H1650. PF-4989216 is a potential cancer drug candidate for erlotinib resistant non-small-cell lung cancer patients with PIK3CA mutation. Synonyms: PF-4989216; PF 4989216; PF4989216. CAS No. 1276553-09-3. Molecular formula: C18H13FN6OS. Mole weight: 380.401. | |
TD52 Quick inquiry Where to buy Suppliers range | TD52 is a potent CIP2A inhibitor with increased apoptosis in HCC cells compared to erlotinib (IC50 values of 0.9, 0.9, 0.8 and 1.2 μM in HA22T, Hep3B, PLC5 and Sk-Hep1 cell lines, respectively). CIP2A-dependent p-Akt downregulation modulates TD52-induced apoptosis in TNBC. TD52-induced tumor inhibition was associated with reactivation of PP2A and downregulation of CIP2A and p-Akt in vivo. Uses: Antitumor agent. Synonyms: N2,N3-bis(3-Ethynylphenyl)-2,3-quinoxalinediamine. Grades: 99%. CAS No. 1798328-24-1. Molecular formula: C24H16N4. Mole weight: 360.41. |