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It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1-Beta; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4'-C-isobutyrate, S-ester with N-acetyl-L-cysteine; L-Cysteine, N-acetyl-, (2-((2-(acetylamino)-2-carboxyethyl)thio)-1-carboxypropyl)carbamodithioate (ester), 1'-4'-ester with 5-(6-O-acetyl-3-O-(2,6-dideoxy-3-O-methyl-4-C-(1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid. CAS No. 101411-71-6. Molecular formula: C43H62N4O23S3. Mole weight: 1099.16.
Silane,[(1-ethoxy-2-methyl-1-propen-1-yl)oxy]trimethyl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-ethoxy-2-methyl-1-trimethylsiloxyprop-1-ene; trimethylsilyl enol ether of ethyl isobutyrate. Product Category: Siloxanes. Appearance: Transparent liquid. CAS No. 31469-16-6. Molecular formula: C9H20O2Si. Mole weight: 188.34. Purity: 95%+. IUPACName: (1-ethoxy-2-methylprop-1-enoxy)-trimethylsilane. Canonical SMILES: CCOC(=C(C)C)O[Si](C)(C)C. Density: 0.861 g/cm³. Product ID: ACM31469166. Alfa Chemistry ISO 9001:2015 Certified.
1-(Isobutyryloxy) Ethyl 3-Oxo-2-azaspiro[4,5]decane-2-carboxylate is derived from Gabapentin (G117250), which is an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C16H25NO5, Molecular Weight: 311.37. US Biological Life Sciences.
5-amino-3-((4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one is an imperative pharmaceutical compound, exhibiting remarkable applications in research of diverse ailments encompassing viral infections and cancer. Synonyms: (R)-2-(((R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate. CAS No. 1229414-16-7. Molecular formula: C9H12N6O4. Mole weight: 268.23.
It is produced by the strain of Streptomyces caelestis NRRL 2418. It has anti-gram-positive bacterial activity. Synonyms: Isobutyric acid 2-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-{(R)-2-methoxy-1-[(1-methyl-pyrrolidine-2-carbonyl)-amino]-propyl}-tetrahydro-pyran-2-ylsulfanyl)-ethyl ester. CAS No. 42715-01-5. Molecular formula: C21H38N2O8S. Mole weight: 478.60.
Corynecin III
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grade: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29.
dG(iBu)-3'-PS Phosphoramidite is a deoxyguanosine-derived phosphoramidite designed for oligonucleotide synthesis incorporating a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, providing enhanced nuclease resistance and improved biological stability for the resulting oligonucleotides. The guanine base is protected with an isobutyryl (iBu) group at the N2 position to prevent side reactions during synthesis while maintaining proper base-pairing properties. This phosphoramidite is widely used in therapeutic applications, such as antisense oligonucleotides and siRNA, where increased enzymatic resistance, stability, and prolonged activity are essential for performance. Synonyms: 5'-DMT-dG(iBu)-3'-PS-Phosphoramidite; dG(iBu) ThioPhosphamidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; S-(2-(((((2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate. Grade: ≥90%. CAS No. 178272-31-6. Molecular formula: C48H53N6O8PS2. Mole weight: 937.08.
Di-Methylated Fidaxomicin
Di-Methylated Fidaxomicin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dimethoxybenzoate. CAS No. 185248-68-4. Molecular formula: C54H78Cl2O18. Mole weight: 1084.46. Catalog: APB185248684.
Ethyl Isobutyrylacetate
Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences.
Guanosine, 3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-N-(2-methyl-1-oxopropyl)?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a pivotal constituent, emanates as a linchpin in the explicit domain of nucleic acid synthesis, intently within DNA and RNA exploration. It confers enhanced prospects for manufacturing modified nucleotides as well as derivatives pertaining to nucleic acids, necessitated for investigations encompassing the structural, functional and behavioral attributes pertinent to DNA and RNA molecules, rendering significant insights. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-ethoxy-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 2299279-11-9. Molecular formula: C45H57N8O7P. Mole weight: 852.96.
HMTase Inhibitor IX, MM-102 (Histone Methyltransferase Inhibitor IX, MM102, (S) -N- (bis (4-Fluoro phenyl ) methy l )-1- (2- (2-ethyl -2-isobutyramidobutanamid o)-5-guanidinopentanamido) cyclopentane carboxami de , TFA)
A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50 = 0.4nM). Shown to reduce HoxA9 and Meis-1 mRNA expression in myeloblasts derived from MLL1-AF9-transduced murine bone marrow cells (50uM for 96 h) and preferentially inhibit the growth of MLL1-AF4-harboring MV4;11 and MLL1-ENL-harboring KOPN8 leukemia cultures (GI50 in 7 days = 25uM) via apoptosis induction, while exhibiting much reduced potency against BCR-ABL-dependent K562 cells (GI50 in 7 days = 84uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O? · CF?CO?H. US Biological Life Sciences.
Worldwide
Ibopamine Hydrochloride
Ibopamine Hydrochloride, the prodrug of epinine, is a sympathomimetic drug used in ophthalmology. It induces mydriasis. It acts as an agonist on Dopamine receptor D1 and α-adrenergic receptors and has been studied for the treatment of congestive heart failure. Synonyms: 2-Methylpropanoic Acid 1,1'-[4-[2-(Methylamino)ethyl]-1,2-phenylene] Ester Hydrochloride; 3,4-Di-O-isobutyrylepinine Hydrochloride; Inopamil; Scandine. Grade: ≥95%. CAS No. 75011-65-3. Molecular formula: C17H26ClNO4. Mole weight: 343.85.
iBu-G-(S)-GNA phosphoramidite
Bz-G-(S)-GNA phosphoramidite: A Potent Anticancer and Antiviral Reagent for DNA Synthesis and Modification. This widely employed derivative is recognized for its high-purity and stability, enabling the synthesis of oligonucleotides with amplified efficacy and selectivity. Renowned for its use in drug discovery and development, the Bz-G-(S)-GNA nucleoside intermediate supports treatment of devastating conditions like HIV and cancer. Synonyms: 2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxytriphenyl)methyl-N2-isobutyryl-(S)-9-(2,3-dihydroxypropyl)guanine; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]methyl]ethyl 2-cyanoethyl ester; (S)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (S)-GNA-G(iBu) phosphoramidite; DMT-G(iBu)-(S)-GNA Phosphoramidite. Grade: ≥98%. CAS No. 182625-68-9. Molecular formula: C44H52N7O7P. Mole weight: 797.88.
(R)-2-(((S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate. Uses: Designed for use in research and industrial production. Product Category: Nucleosides. CAS No. 1120329-60-3. Molecular formula: C42H43N5O9. Mole weight: 761.83. Purity: 0.95. Product ID: PR1120329603. Alfa Chemistry ISO 9001:2015 Certified.
Sulbutiamine
Sulbutiamine (isobutyryl thiamine disulfide) is a lipophilic derivative of thiamine used for the treatment of asthenia and other related pathological conditions. Sulbutiamine is available over-the-counter in several countries as a component of nutritional supplements. Group: Biochemicals. Alternative Names: 2-Methylpropanoic Acid 1, 1'- [Dithiobis [3- [1- [ [ (4-amino-2-methyl-5-pyrimidinyl) methyl] formylamino] ethylidene] -3, 1-propanediyl] ] Ester; Bisibutiamine; O-Isobutyroylthiamine Disulfide; O-Isobutyrylthiamine Disulfide; Vitaberin. Grades: Highly Purified. CAS No. 3286-46-2. Pack Sizes: 1g. US Biological Life Sciences.
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