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| Product | Description | |
|---|---|---|
| Farnesyl pyrophosphate ammonium | Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Farnesyl diphosphate ammonium. CAS No. 116057-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113037C. |  |
| Farnesyl Pyrophosphate ammonium salt | Cas No. 116057-57-9. |  |
| Farnesyl Pyrophosphate Triammonium Salt | Isoprenoid from the intracellular mevalonate pathway used for prenylation of several low molecular mass G proteins, including Ras. Group: Biochemicals. Alternative Names: Diphosphoric Acid P-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester Ammonium Salt; (E,E)-Diphosphoric Acid Mono(3,7,11-trimethyl-2,6,10-dodecatrienyl) Ester Triammonium Salt. Grades: Highly Purified. CAS No. 116057-57-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| (2E,6E)-farnesyl diphosphate synthase | Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. The enzyme will not accept larger prenyl diphosphates as efficient donors. Group: Enzymes. Synonyms: farnesyl-diphosphate synthase; geranyl transferase I; prenyltransferase; farnesyl pyrophosphate synthetase; farnesylpyrophosphate synthetase; geranyltranstransferase. Enzyme Commission Number: EC 2.5.1.10. CAS No. 37277-79-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2715; (2E,6E)-farnesyl diphosphate synthase; EC 2.5.1.10; 37277-79-5; farnesyl-diphosphate synthase; geranyl transferase I; prenyltransferase; farnesyl pyrophosphate synthetase; farnesylpyrophosphate synthetase; geranyltranstransferase. Cat No: EXWM-2715. |  |
| (2Z,6Z)-farnesyl diphosphate synthase | This enzyme, originally characterized from wild tomato, specifically forms (2Z,6Z)-farnesyl diphosphate via neryl diphosphate and isopentenyl diphosphate. In wild tomato it is involved in the biosynthesis of several sesquiterpenes. See also EC 2.5.1.68 [(2Z,6E)-farnesyl diphosphate synthase] and EC 2.5.1.10 [(2E,6E)-farnesyl diphosphate synthase]. Group: Enzymes. Synonyms: cis,cis-farnesyl diphosphate synthase; Z,Z-FPP synthase; zFPS; Z,Z-farnesyl pyrophosphate synthase. Enzyme Commission Number: EC 2.5.1.92. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2831; (2Z,6Z)-farnesyl diphosphate synthase; EC 2.5.1.92; cis,cis-farnesyl diphosphate synthase; Z,Z-FPP synthase; zFPS; Z,Z-farnesyl pyrophosphate synthase. Cat No: EXWM-2831. | |
| 5-epiaristolochene synthase | Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium. Group: Enzymes. Synonyms: 5-epi-aristolochene synthase; tobacco epiaristolochene synthase; farnesyl pyrophosphate cyclase (ambiguous); EAS; TEAS. Enzyme Commission Number: EC 4.2.3.61. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5222; 5-epiaristolochene synthase; EC 4.2.3.61; 5-epi-aristolochene synthase; tobacco epiaristolochene synthase; farnesyl pyrophosphate cyclase (ambiguous); EAS; TEAS. Cat No: EXWM-5222. | |
| all-trans-decaprenyl-diphosphate synthase | This enzyme catalyses the condensation reactions resulting in the formation of all-trans-decaprenyl diphosphate, the isoprenoid side chain of ubiquinone-10 and menaquinone-10. The enzyme adds seven isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: decaprenyl-diphosphate synthase; decaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-prenyltransferase. Enzyme Commission Number: EC 2.5.1.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2830; all-trans-decaprenyl-diphosphate synthase; EC 2.5.1.91; decaprenyl-diphosphate synthase; decaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-prenyltransferase. Cat No: EXWM-2830. | |
| all-trans-octaprenyl-diphosphate synthase | This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate, the isoprenoid side chain of ubiquinone-8 and menaquinone-8. The enzyme adds five isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: octaprenyl-diphosphate synthase; octaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-heptaprenyltranstransferase; trans-prenyltransferase. Enzyme Commission Number: EC 2.5.1.90. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2829; all-trans-octaprenyl-diphosphate synthase; EC 2.5.1.90; octaprenyl-diphosphate synthase; octaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-heptaprenyltranstransferase; trans-prenyltransferase. Cat No: EXWM-2829. | |
| α-Hydroxy farnesyl phosphonic acid | α-Hydroxy farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). Synonyms: Hydroxyfarnesyl phosphate; [(2E,6E)-1-hydroxy-3,7,11-trimethyldodeca-2,6,10-trienyl]phosphonic acid. Grades: ≥98%. CAS No. 148796-53-6. Molecular formula: C15H27O4P. Mole weight: 302.4. | |
| dimethylallyltranstransferase | This enzyme will not accept larger prenyl diphosphates as efficient donors. Group: Enzymes. Synonyms: geranyl-diphosphate synthase; prenyltransferase; dimethylallyltransferase; DMAPP:IPP-dimethylallyltransferase; (2E,6E)-farnesyl diphosphate synthetase; diprenyltransferase; geranyl pyrophosphate synthase; geranyl pyrophosphate synthetase; trans-farnesyl pyrophosphate synthetase. Enzyme Commission Number: EC 2.5.1.1. CAS No. 9032-79-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2714; dimethylallyltranstransferase; EC 2.5.1.1; 9032-79-5; geranyl-diphosphate synthase; prenyltransferase; dimethylallyltransferase; DMAPP:IPP-dimethylallyltransferase; (2E,6E)-farnesyl diphosphate synthetase; diprenyltransferase; geranyl pyrophosphate synthase; geranyl pyrophosphate synthetase; trans-farnesyl pyrophosphate synthetase. Cat No: EXWM-2714. | |
| ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] | Undecaprenyl pyrophosphate synthase catalyses the consecutive condensation reactions of a farnesyl diphosphate with eight isopentenyl diphosphates, in which new cis-double bonds are formed, to generate undecaprenyl diphosphate that serves as a lipid carrier for peptidoglycan synthesis of bacterial cell wall. Group: Enzymes. Synonyms: di-trans,poly-cis-undecaprenyl-diphosphate synthase; undecaprenyl-diphosphate synthase; bactoprenyl-diphosphate synthase; UPP synthetase; undecaprenyl diphosphate synthetase; undecaprenyl pyrophosphate synthetase; di-trans,poly-cis-decaprenylcistransferase. Enzyme Commission Number: EC 2.5.1.31. CAS No. 52350-87-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2769; ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]; EC 2.5.1.31; 52350-87-5; di-trans,poly-cis-undecaprenyl-diphosphate synthase; undecaprenyl-diphosphate synthase; bactoprenyl-diphosphate synthase; UPP synthetase; undecaprenyl diphosphate synthetase; undecaprenyl pyrophosphate synthetase; di-trans,poly-cis-decaprenylcistransferase. Cat No: EXWM-2769. | |
| drimenol cyclase | Drimenol cyclase (EC 3.1.7.7, farnesyl pyrophosphate:drimenol cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase (drimenol-forming). Group: Enzymes. Synonyms: farnesyl pyrophosphate:drimenol cyclase. Enzyme Commission Number: EC 3.1.7.7. CAS No. 146838-17-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3767; drimenol cyclase; EC 3.1.7.7; 146838-17-7; farnesyl pyrophosphate:drimenol cyclase. Cat No: EXWM-3767. | |
| (+)-epicubenol synthase | Requires Mg2+. In the bacteria Streptomyces and the liverwort Heteroscyphus the (+)-isomer is formed in contrast to higher plants where the (-)-isomer is formed. Group: Enzymes. Synonyms: farnesyl pyrophosphate cyclase (ambiguous). Enzyme Commission Number: EC 4.2.3.64. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5225; (+)-epicubenol synthase; EC 4.2.3.64; farnesyl pyrophosphate cyclase (ambiguous). Cat No: EXWM-5225. | |
| farnesyl-diphosphate kinase | ADP can also act as donor. Group: Enzymes. Synonyms: farnesyl pyrophosphate kinase. Enzyme Commission Number: EC 2.7.4.18. CAS No. 50936-43-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3199; farnesyl-diphosphate kinase; EC 2.7.4.18; 50936-43-1; farnesyl pyrophosphate kinase. Cat No: EXWM-3199. | |
| FTase Inhibitor II | FTase Inhibitor II is a cell-permeable analog of farnesyl pyrophosphate (FPP) that potently inhibits FTase with an IC50 of 50-75 nM, and it does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 μM). FTase Inhibitor II is a possible cancer therapeutic agent. Synonyms: Farnesyltransferase Inhibitor II; FTI-II; N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-L-methionine. Grades: ≥80%. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. | |
| geranylgeranyl diphosphate synthase | Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors. Group: Enzymes. Synonyms: geranylgeranyl-diphosphate synthase; geranylgeranyl pyrophosphate synthetase; geranylgeranyl-PP synthetase; farnesyltransferase; geranylgeranyl pyrophosphate synthase; farnesyltranstransferase (obsolete). Enzyme Commission Number: EC 2.5.1.29. CAS No. 9032-58-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2766; geranylgeranyl diphosphate synthase; EC 2.5.1.29; 9032-58-0; geranylgeranyl-diphosphate synthase; geranylgeranyl pyrophosphate synthetase; geranylgeranyl-PP synthetase; farnesyltransferase; geranylgeranyl pyrophosphate synthase; farnesyltranstransferase (obsolete). Cat No: EXWM-2766. | |
| heptaprenyl diphosphate synthase | This enzyme catalyses the condensation reactions resulting in the formation of all-trans-heptaprenyl diphosphate, the isoprenoid side chain of ubiquinone-7 and menaquinone-7. The enzyme adds four isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: all-trans-heptaprenyl-diphosphate synthase; heptaprenyl pyrophosphate synthase; heptaprenyl pyrophosphate synthetase; HepPP synthase; HepPS; heptaprenylpyrophosphate synthetase. Enzyme Commission Number: EC 2.5.1.30. CAS No. 74506-59-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2768; heptaprenyl diphosphate synthase; EC 2.5.1.30; 74506-59-5; all-trans-heptaprenyl-diphosphate synthase; heptaprenyl pyrophosphate synthase; heptaprenyl pyrophosphate synthetase; HepPP synthase; HepPS; heptaprenylpyrophosphate synthetase. Cat No: EXWM-2768. | |
| hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] | The enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate. Group: Enzymes. Synonyms: HexPS (ambiguous); hexaprenyl pyrophosphate synthetase (ambiguous); hexaprenyl diphosphate synthase (ambiguous). Enzyme Commission Number: EC 2.5.1.83. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2821; hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]; EC 2.5.1.83; HexPS (ambiguous); hexaprenyl pyrophosphate synthetase (ambiguous); hexaprenyl diphosphate synthase (ambiguous). Cat No: EXWM-2821. | |
| hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] | The enzyme prefers geranylgeranyl diphosphate to farnesyl diphosphate as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate. Requires Mg2+. Group: Enzymes. Synonyms: HexPS(ambiguous); (all-E) hexaprenyl diphosphate synthase; (all-trans) hexaprenyl diphosphate synthase; hexaprenyl pyrophosphate synthase (ambiguous); HexPPs (ambiguous); hexaprenyl diphosphate synthase (ambiguous). Enzyme Commission Number: EC 2.5.1.82. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2820; hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]; EC 2.5.1.82; HexPS(ambiguous); (all-E) hexaprenyl diphosphate synthase; (all-trans) hexaprenyl diphosphate synthase; hexaprenyl pyrophosphate synthase (ambiguous); HexPPs (ambiguous); hexaprenyl diphosphate synthase (ambiguous). Cat No: EXWM-2820. | |
| Manumycin A | Antibiotic. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50= 30nM). Does not affect geranyl geranyl transferase (IC50=180uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Neutral sphingomyelinase inhibitor. Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Manumycin A (NSC-622141, UFC 1C) | An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50 = 30nM). Does not affect geranyl geranyl transferase (GGTase) (IC50 = 180uM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM).uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| prenyl-diphosphatase | Farnesyl diphosphate is the best substrate tested to date. Group: Enzymes. Synonyms: prenyl-pyrophosphatase; prenol pyrophosphatase; prenylphosphatase. Enzyme Commission Number: EC 3.1.7.1. CAS No. 37288-33-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3760; prenyl-diphosphatase; EC 3.1.7.1; 37288-33-8; prenyl-pyrophosphatase; prenol pyrophosphatase; prenylphosphatase. Cat No: EXWM-3760. | |
| Risedronic acid | Risedronic acid (Risedronate), a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid inhibits blood stages of Plasmodium falciparum ( IC 50 of 20.3 μM). Risedronic acid inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Risedronate. CAS No. 105462-24-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0148. | |
| Risedronic acid sodium | Risedronic acid (Risedronate) sodium, a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid sodium inhibits blood stages of Plasmodium falciparum ( IC 50 of 20.3 μM). Risedronic acid sodium inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Risedronate sodium. CAS No. 115436-72-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0119. | |
| vetispiradiene synthase | The initial internal cyclization produces the monocyclic intermediate germacrene A. Group: Enzymes. Synonyms: vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Enzyme Commission Number: EC 4.2.3.21. CAS No. 192465-18-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5178; vetispiradiene synthase; EC 4.2.3.21; 192465-18-2; vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Cat No: EXWM-5178. | |
| (Z)-2-Hexyl-3-methylmaleic Acid Disodium Salt | A derivative of Chaetomellic acids which are a class of alkyl dicarboxylic acids that were isolated from Chaetomella acutiseta. They are potent and highly specific farnesyl-pyrophosphate (FPP) mimic inhibitors of Ras farnesyl-protein transferase. Group: Biochemicals. Alternative Names: (2Z)-2-Hexyl-3-methyl-2-butenedioic Acid Disodium Salt. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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