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1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: 1-Phenyl-2-oxo-3-oxabicyclo[3.1.0]hexane; Milnacipran Impurity 31. Grades: ≥95%. CAS No. 63106-93-4. Molecular formula: C11H10O2. Mole weight: 174.20.
(1R,2R)-rel-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenyl-cyclopropanecarboxamide is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: (1R,2R)-rel-2-(1,3-Dioxoisoindolin-2-yl)-N,N-diethyl-1-phenylcyclopropanecarboxamide; Cyclopropanecarboxamide, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenyl-, rel-(1R,2R)-. CAS No. 907205-34-9. Molecular formula: C23H24N2O3. Mole weight: 376.45.
(1R,2R)-rel-N,N-Diethyl-2-(hydroxymethyl)-1-phenyl-cyclopropanecarboxamide is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Cyclopropanecarboxamide, N,N-diethyl-2-(hydroxymethyl)-1-phenyl-, (1R,2R)-rel-. CAS No. 1797131-72-6. Molecular formula: C15H21NO2. Mole weight: 247.33.
(1R,2S)-rel-N,N-Diethyl-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-phenyl-cyclopropanecarboxamide is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: rel-((1R,2S)-2-(diethylcarbamoyl)-2-phenylcyclopropyl)methyl 4-methylbenzenesulfonate; Cyclopropanecarboxamide, N,N-diethyl-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-phenyl-, (1R,2S)-rel-; rel-(1R,2S)-N,N-Diethyl-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-phenylcyclopropanecarboxamide. CAS No. 923037-67-6. Molecular formula: C22H27NO4S. Mole weight: 401.52.
1-Trimethyl-(4-vinylbenzyl)aminium chloride
Trimethyl-(4-vinylbenzyl)aminium chloride, an essential biomaterial in gene therapy and delivery, serves as a key intermediate in the pharmaceutical industry for developing drugs against various ailments like cancer and cystic fibrosis. With potent molecular structures, it effectively mitigates diseases and ailments with minimal side effects, proving to be a widely applicable solution in the scientific community. Its versatile function makes it an ideal candidate for further research and potential breakthroughs in the field of biomedicine. Synonyms: (p-Vinylbenzyl)trimethylammonium chloride; (4-ethenylphenyl)methyl-trimethylazanium chloride; N,N,N-trimethyl-1-(4-vinylphenyl)methanaminium chloride. CAS No. 7538-38-7. Molecular formula: C12H18ClN. Mole weight: 211.73.
5-Nitro-2,4-bis(1,1-dimethylethyl)phenyl-carbonic Acid Methyl Ester-d10 is an intermediate used in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603), which is isotopically labeled form of Ivacaftor (I940600), that is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H13D10NO5, Molecular Weight: 319.42. US Biological Life Sciences.
Worldwide
2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers)
2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers) is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C16H23NO5. Mole weight: 309.36.
2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate. (Mixture of Regioisomers)
2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers) is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H23NO5 + C16H23NO5. US Biological Life Sciences.
Worldwide
2,4-Di-tert-butylphenol-d10
2,4-Di-tert-butylphenol-d10 is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. 2,4-Di-tert-butylphenol-d18 is the labelled analogue of 2,4-Di-tert-butylphenol (D429475). A chemical constituent of volatile oils from Catunaregam spinosa fruits. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-50-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C14H12D10O. US Biological Life Sciences.
Worldwide
2-(Aminomethyl)pyrazine
2-(Aminomethyl)pyrazine is a useful synthetic intermediate. It is used to synthesize pyrazolo[4,3-c]pyridinediones as orally bioavailable NADPH oxidase isoform 4 inhibitors for the treatment of idiopathic pulmonary fibrosis. It is also used to prepare pyrazolyl-indoles with the abilities to induce T-cell kinase inhibition. Group: Biochemicals. Grades: Highly Purified. CAS No. 20010-99-5. Pack Sizes: 1g, 5g. Molecular Formula: C5H7N3, Molecular Weight: 109.13. US Biological Life Sciences.
Worldwide
2-Bromo-4-(tert-butyl)-5-nitrophenyl Acetate
2-Bromo-4-(tert-butyl)-5-nitrophenyl Acetate is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C12H14BrNO4. Mole weight: 316.15.
2-Methoxy-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine is an intermediate used to prepare pyridine compounds as modulators of cystic fibrosis transmembrane conductance regulator (CFTR) useful in treatment of CFTR-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1083168-87-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H20BNO3, Molecular Weight: 249.11. US Biological Life Sciences.
3-Amino-4-(1,1-dimethylethyl)-6-[1,1-di(methyl-d3)ethyl-2,2,2-d3]phen-2-d-ol is an intermediate used in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603), which is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-53-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H13D10NO, Molecular Weight: 231.4. US Biological Life Sciences.
Worldwide
4-Hydroxyindole
4-Hydroxyindole is a type of hydroxyindole in which the 1H-indole at position 4 is substituted by a hydroxyl group. 4-Hydroxyindole serves as an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. 4-Hydroxyindole inhibits amyloid fibrillization and induces liver function impairment, thyroid abnormalities, and blood glucose fluctuations in mice. 4-Hydroxyindole holds potential for research in neurodegenerative diseases and metabolic disorders [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380-94-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-34596.
5-Amino-2,4-di-tert-butylphenol
5-Amino-2,4-di-tert-butylphenol is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 5-Amino-2,4-bis(1,1-dimethylethyl)phenol; 5-Amino-2,4-bis(2-methyl-2-propanyl)phenol; Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-. Grades: ≥95%. CAS No. 873055-58-4. Molecular formula: C14H23NO. Mole weight: 221.34.
5-Amino-2,4-di-tert-butylphenol-d9
5-Amino-2,4-di-tert-butylphenol-d9 is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-54-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H14D9NO. US Biological Life Sciences.
Worldwide
6-Amino-2,4-di-tert-butylphenyl Methyl Carbonate
6-Amino-2,4-di-tert-butylphenyl Methyl Carbonate is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 2-amino-4,6-di-tert-butylphenyl methyl carbonate; 2-Amino-4,6-bis(2-methyl-2-propanyl)phenyl methyl carbonate; Carbonic acid, 2-amino-4,6-bis(1,1-dimethylethyl)phenyl methyl ester. Molecular formula: C16H25NO3. Mole weight: 279.37.
6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: 6-Amino-5-(tert-butyl)-3,3-dimethylbenzofuran-2(3H)-one; 2(3H)-Benzofuranone, 6-amino-5-(1,1-dimethylethyl)-3,3-dimethyl-; 6-Amino-3,3-dimethyl-5-(2-methyl-2-propanyl)-1-benzofuran-2(3H)-one; 6-Amino-5-(tert-butyl)-3,3-dimethylbenzo[b]furan-2(3H)-one. Grades: ≥95%. CAS No. 1246213-40-0. Molecular formula: C14H19NO2. Mole weight: 233.31.
8-Methoxycarbonyloctanoyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside, an intricate and highly potent carbohydrate intermediate, holds immense significance in the realm of biomedicine. It serves as a pivotal component for synthesizing drugs that combat glycosylation-related ailments including gaucher disease, pompe disease, Fabry disease, and cystic fibrosis. Synonyms: 8-Methoxycarbonyloctanoyl-2',3',4',6-tetra-O-acetyl-beta-D-galactopyranoside; 93619-78-4; methyl 8-[(2R,5S)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoctanoate. CAS No. 93619-78-4. Molecular formula: C23H36O12. Mole weight: 504.52.
cis-N-Ethyl-2-(hydroxymethyl)-1-phenylcyclopropanecarboxamide is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Rel-(1R,2S)-N-ethyl-2-(hydroxymethyl)-1-phenylcyclopropane-1-carboxamide. CAS No. 69160-65-2. Molecular formula: C13H17NO2. Mole weight: 219.28.
D-Galactosamine-6-O-sulphate
D-Galactosamine-6-O-sulphate is a crucial intermediate compound used in biomedical field to study the therapeutic effects of various drugs. It is commonly employed in research related to liver diseases, particularly in investigating the research of hepatic fibrosand hepatocellular carcinoma. CAS No. 20257-10-7. Molecular formula: C6H13NO8S. Mole weight: 259.23.
Matrix Metalloproteinase-3 from Human, Recombinant
Matrix metalloproteinase-3 (MMP-3) also known as stromelysin-1 and transin (EC 3.4.24.17) cleaves a number of substrates including cartilage proteoglycan, collagen types II, III, IV, V and IX, fibronectin, laminin, and can activate MMP 1. MMP-3 is secreted as 57 and 59 kDa proenzymes and can be activated in vitro by organomercurials (e.g., 4 aminophenylmercuric acetate, APMA) and in vivo by proteases via intermediate forms to a 45 kDa active MMP 3 enzyme. Further autolysis to a 28 kDa form can also occur. MMP-3 is thought to play an important role in pathophysiological degradation processes associated with conditions such as rheumatoid arthritis and cancer cell invas...C 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Enzyme Commission Number: EC 3.4.24.17. CAS No. 79955-99-0. Purity: >95% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 57 kDa. Storage: < -70°C; Avoid freeze/thaw. Form: Lyophilized from 100 mM NaCl, 50 mM HEPES, pH 7.3. Species: Human. Stromelysin 1; EC 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Cat No: NATE-0861.
Methyl 2-(2-Acetoxy-5-(tert-butyl)-4-nitrophenyl)-2-methylpropanoate is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C17H23NO6. Mole weight: 337.37.
N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Carbonic Acid 5-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl Methyl Ester; 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate; 2,4-Bis(2-methyl-2-propanyl)-5-{[(4-oxo-1,4-dihydro-3-quinolinyl)carbonyl]amino}phenyl methyl carbonate. Grades: ≥95%. CAS No. 1246213-45-5. Molecular formula: C26H30N2O5. Mole weight: 450.53.
tert-Butyldimethylsilanol
Tert-Butyldimethylsilanol, a reactive intermediate of paramount importance in the biomedical industry, holds a plethora of applications for synthesizing diverse drugs and siloxane polymers. Its potential in treating liver fibrosis through the inhibition of hepatic stellate cell proliferation has also been probed meticulously. The compound's multifaceted role in medicine and biotechnology accentuates its relevance in scientific research and practical applications. Synonyms: t-Butyldimethylsilanol. Grades: 95%. CAS No. 18173-64-3. Molecular formula: C6H16OSi. Mole weight: 132.28.
Tetracaine EP Impurity A
4-Aminobenzoic acid, also known as PABA, is a B vitamin derivative with UV absorption and antifibrotic properties. 4-Aminobenzoic acid can be generated by some intestinal bacteria, and acts as an intermediate in the synthesis of folate (vitamin B9). It is used in the treatment of fibrotic skin disorder, also can be used as a supplement for fatigue, irritability, depression, etc. Nutritional supplement in health care products. Synonyms: Benzocaine EP Impurity G; p-Aminobenzoic Acid; Bacterial Vitamin H1; p-Carboxyaniline; p-Carboxyphenylamine; Actipol; Amben; PABA; Pabacyd; Pabafilm; Trichochromogenic Factor; Vitamin BX; Vitamin H'. Grades: ≥98.5% by assay. CAS No. 150-13-0. Molecular formula: C7H7NO2. Mole weight: 137.14.
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