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4-Fluorobenzylmagnesium chloride 0.25m&. Group: Salt. Alternative Names: 6-Methoxy-2-naphthylmagnesium bromide solution, 38046-82-1, 646946_ALDRICH, AKOS015916526, I14-51303, 6-Methoxy-2-naphthylmagnesium bromide 0.5 M in Tetrahydrofuran. CAS No. 38046-82-1. Product ID: magnesium; 6-methoxy-2H-naphthalen-2-ide; bromide. Molecular formula: 261.4. Mole weight: C11H9BrMgO. COC1=CC2=CC=[C-]C=C2C=C1. [Mg+2]. [Br-]. DMMNAMUAQVNNBC-UHFFFAOYSA-M. 96%.
BMS 961
BMS 961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist with an IC50 value of 30 nM. Synonyms: BMS961; BMS-961; 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid; Benzoic acid, 3-fluoro-4-[[2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]-. Grades: ≥97% by HPLC. CAS No. 185629-22-5. Molecular formula: C23H26FNO4. Mole weight: 399.45.
Fluorobexarotene
Fluorobexarotene is a RXR agonist (Ki = 12 nM; EC50 = 43 nM at RXRα receptors). Synonyms: 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid. Grades: ≥97% by HPLC. CAS No. 1190848-23-7. Molecular formula: C24H27FO2. Mole weight: 366.47.
Setipiprant
Setipiprant is a potent, orally available and selective CRTH2 antagonist, which is a G protein-coupled receptor for PGD2. It may be a promising target for the treatment of allergic disorders. It was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics at multiple oral doses. It is a drug originally developed by Actelion, but it failed to show sufficient advantages and was discontinued from further development in this application. Later it was developed as a novel treatment for baldness by Kythera. Uses: Setipiprant may be a promising target for the treatment of allergic disorders. Synonyms: ACT-129968; ACT 129968; ACT129968; 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid;ACT129968;2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid;8-Fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-acetic acid; KYTH-105; KYTH105; KYTH 105. Grades: >98 %. CAS No. 866460-33-5. Molecular formula: C24H19FN2O3. Mole weight: 402.42.
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