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Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14407A.
Fosaprepitant dimeglumine
Fosaprepitant is a selective NK-1 receptor antahonist. It is a water-soluble phosphoryl prodrug for Aprepitant. Synonyms: MK-0517; MK 0517; MK0517. Grade: >98%. CAS No. 265121-04-8. Molecular formula: C23H22F7N4O6P.2C7H17NO5. Mole weight: 1004.83.
Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences.
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(1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine
(1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'R,2R,3R)-Fosaprepitant Dimeglumine
(1'R,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine
(1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine
(1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'R,2S,3R)-Fosaprepitant Dimeglumine
(1'R,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Uses: Antiemetics. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine
(1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'R,2S,3S)-Fosaprepitant Dimeglumine
(1'R,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine
(1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'S,2R,3R)-Fosaprepitant Dimeglumine
(1'S,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine
(1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'S,2R,3S)-Fosaprepitant Dimeglumine
(1'S,2R,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine
(1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'S,2S,3R)-Fosaprepitant Dimeglumine
(1'S,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
(1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine
(1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84.
(1'S,2S,3S)-Fosaprepitant Dimeglumine
(1'S,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
Defluoro Fosaprepitant Dimeglumine
Defluoro Fosaprepitant Dimeglumine is an extraordinary pharmaceutical compound, finding extensive application in the biomedical research with the potent blockade of central nervous system-associated substance P/neurokinin 1 receptors. Grade: > 95%. Molecular formula: C37H57F6N6O16P. Mole weight: 986.87.
ent-Defluoro Fosaprepitant Dimeglumine
ent-Defluoro Fosaprepitant Dimeglumine is an eminent biomedical compound, used in studying chemotherapy-induced nausea and vomiting. Its profound pharmacological mechanism as a neurokinin-1 receptor antagonist profoundly impedes the detrimental interaction between substance P and its specific receptor. Grade: > 95%. Molecular formula: C37H57F6N6O16P. Mole weight: 986.87.
Fosaprepitant-[d4] Dimeglumine
Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86.
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