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Acts on blood group substance, and can use a number of 2-fucosyl-galactosides as acceptors. Group: Enzymes. Synonyms: UDP-galactose:O-α-L-fucosyl(1?2)D-galactose α-D-galactosyltransferase; UDPgalactose:glycoprotein-α-L-fucosyl-(1,2)-D-galactose 3-α-D-galactosyltransferase; [blood group substance] α-galactosyltransferase; blood-group substance B-dependent galactosyltransferase; glycoprotein-fucosylgalacto. Enzyme Commission Number: EC 2.4.1.37. CAS No. 37257-33-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2583; fucosylgalactoside 3-α-galactosyltransferase; EC 2.4.1.37; 37257-33-3; UDP-galactose:O-α-L-fucosyl(1?2)D-galactose α-D-galactosyltransferase; UDPgalactose:glycoprotein-α-L-fucosyl-(1,2)-D-galactose 3-α-D-galactosyltransferase; [blood group substance] α-galactosyltransferase; blood-group substance B-dependent galactosyltransferase; glycoprotein-fucosylgalactoside α-galactosyltransferase; histo-blood group B transferase; histo-blood substance B-dependent galactosyltransferase; UDP-galactose:α-L-fucosyl-1,2-D-galactoside 3-α-D-galactosyltransferase; UDP-galactose:α-L-fucosyl-(1?2)-D-galactoside 3-α-D-galactosyltransferase. Cat No: EXWM-2583.
Fucosyl-GM1 ganglioside
Fucosyl-GM1 ganglioside is an indispensable biomolecule with applicationa in the research of a myriad of afflictions encompassing neurodegenerative ailments, most notably Alzheimer's disease and Parkinson's disease. Synonyms: Fucosylated monosialoganglioside GM1. CAS No. 71812-11-8. Molecular formula: C79H141N3O35. Mole weight: 1692.96.
Fucosyl GM1 oligosaccharide
Fucosyl GM1 oligosaccharide is a multifaceted biomedical compound with immune response augmentation and neuroprotective potency. Fucosyl GM1 oligosaccharide has applications in research of Alzheimer's disease, Parkinson's disease and multiple sclerosis. Synonyms: Fuca1-2Galb1-3GalNAcb1-4(Neu5Aca2-3)Galb1-4Glc. Molecular formula: C43H71N2O33Na. Mole weight: 1167.01.
2'',3'',4''-Tri-O-benzylfucosyllactose
2'',3'',4''-Tri-O-benzylfucosyllactose, a complex carbohydrate, serves as an invaluable tool for deciphering the intricate interplay between pathogenic bacteria and their host cells. Researchers have extensively explored its potential as a therapeutic agent, particularly in the context of combatting devastating conditions like tuberculosis and pneumonia. In addition, this compound serves as an indispensable reference standard, enabling scientists to precisely investigate the role that fucosylated glycans play in cellular signaling and interactions. Grades: 90%. Molecular formula: C39H50O15. Mole weight: 758.81.
2'-Fucosyllactose
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 2'-FL. CAS No. 41263-94-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9965.
2'-Fucosyllactose
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines. Group: Inhibitors. Alternative Names: 5-O-DMT-thymidine 3'. CAS No. 41263-94-9. Molecular formula: C18H32O15. Mole weight: 488.44. Appearance: Off-white solid. Purity: 0.9. IUPACName: (2R,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,3,5,6-tetrahydroxyhexanal. Canonical SMILES: C[C@H]1[C@H] ([C@H] ([C@@H] ([C@@H] (O1)O[C@@H]2[C@H] ([C@H] ([C@H] (O[C@H]2O[C@H] ([C@@H] (CO)O)[C@@H] ([C@H] (C=O)O)O)CO)O)O)O)O)O. Density: 1.548 g/ml. Catalog: ACM41263949.
2-Fucosyllactose-APD-BSA
2-Fucosyllactose-APD-BSA is a vital compound in the biomedical industry utilized for drug development. It serving as a valuable tool for studying deciphering glycan recognition processes associated with fucosylated oligosaccharides. This compound aids in investigating therapeutic interventions for reserching diseases like cancer, inflammatory disorders, and viral infections involving fucosylation. Synonyms: Fuc-a-1,2-Gal-b-1,4-Glc-APD-BSA.
2'-Fucosyllactose-biotin
2'-Fucosyllactose-biotin, an oligosaccharide with biotin labeling, serves as an effective probe for identifying proteins that bind to fucosylated glycans in research studies. It also facilitates investigating the biological significance of fucosylation in diverse cells and tissues in laboratory settings, however, it doesn't have any therapeutic value in treating medical ailments. Synonyms: 2'FL-biotin. Molecular formula: C36H64N6O16S. Mole weight: 868.99.
2-Fucosyllactose-BSA
2'Fucosyllactose-BSA(2'FL-BSA) (3 atom spacer)
2'Fucosyllactose-BSA(2'FL-BSA) (3 atom spacer) is an unrivaled and invaluable instrument utilized in the biomedical discipline to scrutinize and gain comprehension of the association between fucosylated glycans and precise proteins, for instance, pathogen-binding proteins. Its utilization in the research of maladies entailing said connections, for instance, Hepatitis C and HIV, is widely adopted within the scientific community.
2-Fucosyllactose peracetate
2-Fucosyllactose peracetate is an invaluable biomedical substance, effectively utilized for studying a myriad of intricate gastrointestinal maladies encompassing the vexatious irritable bowel syndrome and the debilitating ulcerative colitis. Molecular formula: C38H52O25. Mole weight: 908.80.
2'-Fucosyllactose peracetate
2'-Fucosyllactose peracetate, an intriguing carbohydrate derivative, has sparked interest in biomedicine research, as its therapeutic potential in treating bacterial infections and inflammation within the gut is explored. Additionally, its application in managing neurodegenerative disorders displays a wealth of prospects. Grades: 90%. Molecular formula: C38H52O25. Mole weight: 908.80.
2-O-Fucosyllactulose
2-O-Fucosyllactulose is an essential compound functioning as a proficient prebiotic. It can adeptly kindle the proliferation of salutary bacteria within the gut. Synonyms: O-6-Deoxy-a-L-galactopyranosyl-(1?2)-O-b-D-galactopyranosyl-(1?4)-D-fructose. CAS No. 1672706-30-7. Molecular formula: C18H32O15. Mole weight: 488.44.
3-Fucosyllactose
3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Fucosyl-D-lactose. CAS No. 41312-47-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N10528.
3-Fucosyllactose
3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function. Group: Inhibitors. Alternative Names: 3-FUCOSYLLACTOSE;(2S,3S,4R,5S,6S)-2-[(2R,3R,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-oxan-4-yl]oxy-6-methyl-oxane-3,4,5-triol;3-FL,α-L-Fuc-(1-3)-[β-D-Gal-(1-4)]-D-Glc;3-Fucosyllactose (3FL);3-FL;α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-D-Glc. CAS No. 41312-47-4. Molecular formula: C18H32O15. Mole weight: 488.44. Appearance: Solid. Purity: ≥99.0%. Canonical SMILES: O[C@@H] ([C@@H] ([C@@H] ([C@@H] (O1)C)O)O)[C@@H]1O[C@H] ([C@@H] (O)C=O)[C@@H] ([C@H] (O)CO)O[C@@H]2O[C@@H] ([C@@H] ([C@@H] ([C@H]2O)O)O)CO. Catalog: ACM41312474.
3-Fucosyllactose
3-fucosyllactose is a trisaccharide that is lactose in which the hydroxy group at position 3 of the glucosyl moiety has undergone formal condensation with the anomeric hydroxy group of fucose (6-deoxy-L-galactose) to give the corresponding glycoside. It is one of the major fucosylated oligosaccharides found in human breast milkIt, and has a role as a human metabolite. It is functionally related to a lactose. Synonyms: 3FL; Galb-4(Fuca-3)Glc; O-6-Deoxy-α-L-galactopyranosyl-(1?3)-O-[β-D-galactopyranosyl-(1?4)]-D-glucose; 3-O-α-L-Fucopyranosyllactose; 3-O-Fucosyllactose; 6-deoxy-alpha-L-galactopyranosyl-(1->3)-[beta-D-galactopyranosyl-(1->4)]-D-glucopyranose. Grades: ≥95%. CAS No. 41312-47-4. Molecular formula: C18H32O15. Mole weight: 488.44.
3-Fucosyllactose-biotin
3-Fucosyllactose-biotin is a cutting-edge biomedical compound, emerging as an indispensable tool in the realm of research and diagnostics. By meticulously unraveling intricate fucosylation patterns and delving into the realm of disease biomarkers like cancer, inflammation is and autoimmune disorders, this extraordinary concoction assumes the role of a specific probe. Synonyms: 3FL-biotin. Molecular formula: C34H59N5O17S. Mole weight: 841.92.
This enzyme is the product of the Lewis blood group gene. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. Although it is a 4-fucosyltransferase, it has a persistent 3-fucosyltransferase activity towards the glucose residue in free lactose. This enzyme fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3, unlike EC 2.4.1.152, 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase, which fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4. Enzymes catalysing the 4-α-fucosylation of the GlcNAc in β-D-Gal-(1?3)-β-GlcNAc sequences (with some activity also as 3-α-fucosyltransferases) are present in plants, where the function in vivo is the modification of N-glycans. In addition, the fucTa gene of Helicobacter strain UA948 encodes a fucosyltransferase with both 3-α- and 4-α-fucosyltransferase activities. Group: Enzymes. Synonyms: (Lea)-dependent (α-3/4)-fucosyltransferase; α(1,3/1,4) fucosyltransferase III; α-(1?4)-L-fucosyltransferase; α-4-L-fucosyltransferase; β-acetylglucosaminylsaccharide fucosyltransferase; FucT-II; Lewis α-(1?3/4)-fucosyltransferase; Lewis blood group α-(1?3/4)-fucosyltransferase; Lewis(Le) blood . Enzyme Commi
3'-N-Acetylneuraminyl-3-fucosyllactose sodium salt
3-Sialyl-3-fucosyllactose is an esteemed compound employed in the biomedical sector, having been extensively investigated in the realm of therapeutic developments targeting a multitude of afflictions encompassing gastrointestinal maladies, respiratory contagions is and inflammatory syndromes alike. Armed with a distinctive architectural arrangement and endowed with an intricate orchestration of biological functionalities, the auspicious therapeutic prospects of 3-Sialyl-3-fucosyllactose emerge prominently in curbing the progression of numerous incapacitating pathologies. Synonyms: NeuNAc-a2-3-Gal-b1-4(Fuc-a1-3)Glc. Molecular formula: C29H49NO23. Mole weight: 779.71.
3'-Sialyl-3-fucosyllactose
3'-Sialyl-3-fucosyllactose is a profoundly impactful compound, holding immense potential for studying diverse diseases and conditions pervasive including viral and bacterial infections, autoimmune disorders. Synonyms: NeuNAc-a2-3-Gal-b1-4(Fuc-a1-3)Glc. Grades: 90%. CAS No. 122560-33-2. Molecular formula: C29H49NO23. Mole weight: 779.71.
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3. Group: Enzymes. Synonyms: Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fu. Enzyme Commission Number: EC 2.4.1.152. CAS No. 39279-34-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2378; 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase; EC 2.4.1.152; 39279-34-0; Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fucosyltransferase; GDP-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-α-L-fucosyltransferase. Cat No: EXWM-2378.
6-a-Fucosyl chitobiose
6-a-Fucosyl chitobiose is a compound used in the research of various diseases playing a crucial role in modulating immune responses and cell adhesion processes. This compound exhibits potent anti-inflammatory properties, making it an effective compound for studying autoimmune disorders such as rheumatoid arthritand multiple sclerosis. Furthermore, it shows promising potential in targeting cancer cells due to its ability to inhibit tumor growth and metastasis. Synonyms: GlcNb1-4{Fuca1-6}GlcN.
6-Fucosyllactose
6-Fucosyllactose is a bioactive oligosaccharide functioning as a prebiotic facilitating the proliferation of advantageous Bifidobacterium spp. Molecular formula: C18H32O15. Mole weight: 488.44.
6'-Fucosyllactose
6'-Fucosyllactose, an indispensable compound in the realm of biomedicine, has garnered considerable attention due to its profound therapeutic capabilities. By virtue of its remarkable capacity to modulate the gastrointestinal microbiota, it exhibits encouraging prospects in mitigating afflictions besieging the gastrointestinal tract and curtailing susceptibility to infections. Furthermore, its hypothesized immunomodulatory properties may offer viable avenues for the management and prophylaxis of specific maladies. Synonyms: (2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-((((2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal; 80756-86-1. Grades: 95%. CAS No. 80756-86-1. Molecular formula: C18H32O15. Mole weight: 488.44.
α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.65. CAS No. 37277-69-3. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter mustelae. Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Cat No: NATE-1484.
α-1-3,4 Fucosyltransferase, helicobacter pylori
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (EC 2.4.1.65) (Hp3/4FT) can be found in Helicobacter pylori. alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) catalyzes fucose transfer from donor GDP-beta-l-fucose to the GlcNAc [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-1-3,4 FucT; Hp3/4FT. CAS No. 37277-69-3. Pack Sizes: 1 U; 25 U; 5 U. Product ID: HY-E70058.
α-1,3-fucosyltransferase from Helicobacter pylori, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter pylori. glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha 1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Cat No: NATE-1483.
Asialo, galactosylated, fucosylated, biantennary (G1F) - a formidable glycan structure with therapeutic potential, capable of wrangling a plethora of diseases, ranging from the insidious grip of cancer to the fiery inflammation. Studies indicate that G1F galvanizes antibody-dependent cellular cytotoxicity (ADCC), augments pharmacokinetics and reinforces the stability of recombinant proteins. It is a versatile tool in glycoengineering, which can be exploited to optimize the therapeutic properties of therapeutic proteins. Molecular formula: C62H104N4O45. Mole weight: 1625.49.
Difucosyl-para-lacto-N-hexaose I
Difucosyl-para-lacto-N-hexaose I is an indispensable constituent forged from fucosylated oligosaccharides. Displaying an extraordinary configuration, Difucosyl-para-lacto-N-hexaose I finds applicability in the research of sundry afflictions such as cancer and autoimmune maladies. Synonyms: Lewis b octasaccharide linear; DFpLNH. Molecular formula: C53H91N2O38. Mole weight: 1364.28.
galactoside 2-α-L-fucosyltransferase
Free lactose can act as acceptor. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. The action on glycolipid was previously listed as EC 2.4.1.89. Group: Enzymes. Synonyms: blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fuco. Enzyme Commission Number: EC 2.4.1.69. CAS No. 56093-23-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2612; galactoside 2-α-L-fucosyltransferase; EC 2.4.1.69; 56093-23-3; blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fucose-lactose fucosyltransferase; guanosine diphospho-L-fucose-lactose fucosyltransferase; guanosine
The enzyme is involved in the biosynthesis of the O-polysaccharide repeating unit of the bacterium Escherichia coli serotype O86. Group: Enzymes. Synonyms: WbnK. Enzyme Commission Number: EC 2.4.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2543; GDP-Fuc:β-D-Gal-1,3-α-D-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,2-fucosyltransferase; EC 2.4.1.308; WbnK. Cat No: EXWM-2543.
glycoprotein 3-α-L-fucosyltransferase
Requires Mn2+. The enzyme transfers to N-linked oligosaccharide structures (N-glycans), generally with a specificity for N-glycans with one unsubstituted non-reducing terminal GlcNAc residue. This enzyme catalyses a reaction similar to that of EC 2.4.1.68, glycoprotein 6-α-L-fucosyltransferase, but transferring the L-fucosyl group from GDP-β-L-fucose to form an α1,3-linkage rather than an α1,6-linkage. The N-glycan products of this enzyme are present in plants, insects and some other invertebrates (e.g., Schistosoma, Haemonchus, Lymnaea). Group: Enzymes. Synonyms: GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamine (Fuc to (Fucα1?6GlcNAc)-Asn-peptide) α1?3-fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. α-fucosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2442; glycoprotein 3-α-L-fucosyltransferase; EC 2.4.1.214; 68247-53-0; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamin
glycoprotein 6-α-L-fucosyltransferase
This enzyme catalyses a reaction similar to that of EC 2.4.1.214, glycoprotein 3-α-L-fucosyltransferase, but transfers the L-fucosyl group from GDP-β-L-fucose to form an α1,6-linkage rather than an α1,3-linkage. Group: Enzymes. Synonyms: GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-link. Enzyme Commission Number: EC 2.4.1.68. CAS No. 9033-8-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2611; glycoprotein 6-α-L-fucosyltransferase; EC 2.4.1.68; 9033-08-3; GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?3)-[N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?6)]-β-D-mannosyl-(1?4)-N-acetyl-β-D-glucosaminyl-
Acts on blood group substance, and can use a number of 2-fucosyl-galactosides as acceptors. Group: Enzymes. Synonyms: A-transferase; histo-blood group A glycosyltransferase (Fucα1?2Galα1?3-N-acetylgalactosaminyltransferase); UDP-GalNAc:Fuc&. Enzyme Commission Number: EC 2.4.1.40. CAS No. 9067-69-0. α-1,3-N-acetyl-galactosaminyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2587; glycoprotein-fucosylgalactoside α-N-acetylgalactosaminyltransferase; EC 2.4.1.40; 9067-69-0; A-transferase; histo-blood group A glycosyltransferase (Fucα1?2Galα1?3-N-acetylgalactosaminyltransferase); UDP-GalNAc:Fucα1?2Galα1?3-N-acetylgalactosaminyltransferase; α-3-N-acetylgalactosaminyltransferase; blood-group substance α-acetyltransferase; blood-group substance A-dependent acetylgalactosaminyltransferase; fucosylgalactose acetylgalactosaminyltransferase; histo-blood group A acetylgalactosaminyltransferase; histo-blood group A transferase; UDP-N-acetyl-D-galactosamine:α-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine:glycoprotein-α-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase. Cat No: EXWM-2587.
Glycyl-2-fucosyllactose
Glycyl-2-fucosyllactose is an intriguing bioactive compound prevalent in the biomedical sector, used for studying diverse ailments encompassing cancer, inflammation and gastrointestinal disturbances. Molecular formula: C20H36N2O15. Mole weight: 544.50.
Glycyl-2'-fucosyllactose
Glycyl-2'-fucosyllactose, a remarkable biomedicine renowned for its miraculous therapeutic potential in the biomedical realm, exerts its profound impact upon the intricate treatment of sundry diseases. Through its praiseworthy attributes as an immunomodulator, it has been scientifically substantiated to augment immune responses while simultaneously mitigating the severity of infections. Synonyms: Glycyl-2'-fucosyllactose (2'-FL-gly); Fucα1-2Galβ1-4Glc-Gly-NH2. Grades: 95%. Molecular formula: C20H36N2O15. Mole weight: 544.50.
Glycyl-3-fucosyllactose
Glycyl-3-fucosyllactose is an extraordinary compound widely employed in the research of diverse gastrointestinal disorders. Synonyms: Glycyl-3-fucosyllactose (3-FL-gly); Fucα1-3Galβ1-4Glc-Gly-NH2. Grades: 95%. Molecular formula: C20H36N2O15. Mole weight: 544.50.
Glycyl-3'-fucosyllactose
Glycyl-3'-fucosyllactose is an intricate and multifaceted biomedical compound, used for studying inflammatory cascades and immune-mediated maladies. I. Molecular formula: C20H36N2O15. Mole weight: 544.50.
Glycyl-asialo, galactosylated fucosylated biantennary is an intricate compound, finding its applications in the research and exploration of cancer, autoimmune disorders, and infectious diseases. Molecular formula: C70H118N6O50. Mole weight: 1843.70.
Monofucosyl (1-3)-iso-lacto-N-octaose
Monofucosyl (1-3)-iso-lacto-N-octaose is an invaluable biomedicine product, extensively employed in scientific investigations to unravel the intricate roles of carbohydrates in diverse biological processes. This synthetic oligosaccharide serves as a remarkable molecular probe, facilitating the meticulous study of fucosylated glycans. Synonyms: O-beta-D-Galactopyranosyl-(1-3)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-3)-O-beta-D-galactopyranosyl-(1-4)-O-[6-deoxy-alpha-L-galactopyranosyl-(1-3)]-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-6)-O-[O-beta-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-3)]-O-beta-D-galactopyranosyl-(1-4)-D-glucose; MFiLNO (1-3). Grades: ≥95%. CAS No. 692776-59-3. Molecular formula: C60H101N3O45. Mole weight: 1584.44.
Monofucosyllacto-N-hexaose III
Monofucosyllacto-N-hexaose III, an imperative biomedicine, serves as a remarkable therapeutic solution within the biomedical domain. By selectively targeting distinct pharmaceuticals, this exquisite composition plays a vital role in combating an array of ailments comprising cancer, inflammation, and microbial infections. Synonyms: MFLNH III; fucosyllacto-N-hexaose III; alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc-(1->6)-[beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->3)]-beta-D-Galp-(1->4)-D-Glcp; 6-deoxy-alpha-L-galactopyranosyl-(1->3)-[beta-D-galactopyranosyl-(1->4)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->6)-[beta-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranosyl-(1->4)-D-glucopyranose; Galb1-4(Fuca1-3)GlcNAcb1-6(Galb1-3GlcNAcb1-3)Galb1-4Glc. Grades: ≥90%. CAS No. 96656-34-7. Molecular formula: C46H78N2O35. Mole weight: 1219.12.
Monofucosyl-para-lacto-N-hexaose IV
Monofucosyl-para-lacto-N-hexaose IV, a remarkable compound, serves as a pivotal asset within the biomedical realm. Embracing its inherent medicinal prowess, this extraordinary substance exhibits unparalleled capabilities in combatting a myriad of maladies. Synonyms: MFpLNH IV; fucosyl-p-lacto-N-hexaose IV; Fucosyl-para-lacto-N-hexaoseIV; β -Gal-(1?3)-β -GlcNAc-(1?3)-β -Gal-(1-4)(α -Fuc-[1?3])-β -GlcNAc-(1?3)-β -Gal-(1?4)-Glc; D-Glucose, O-6-deoxy-α -L-galactopyranosyl-(1->3)-O-[O-β -D-galactopyranosyl-(1->3)-O-2-(acetylamino)-2-deoxy-β -D-glucopyranosyl-(1->3)-β -D-galactopyranosyl-(1->4)]-O-2-(acetylamino)-2-deoxy-β -D-glucopyranosyl-(1->3)-O-β -D-galactopyranosyl-(1->4)-. Grades: ≥95%. CAS No. 115236-58-3. Molecular formula: C46H78N2O35. Mole weight: 1219.12.
N-Acetylneuraminyl-fucosyllacto-N-neo-tetraose from human milk
O-Fucosylpeptide 3-β-N-acetylglucosaminyltransferases are the products of fringe genes. O-linked fucose is an unusual form of glycosylation where the fucose is attached directly to proteins through the hydroxy groups of Ser or Thr residues. Group: Enzymes. Synonyms: O-fucosylpeptide β-1,3-N-acetylglucosaminyltransferase; fringe (ambiguous). Enzyme Commission Number: EC 2.4.1.222. CAS No. 299203-70-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2451; O-fucosylpeptide 3-β-N-acetylglucosaminyltransferase; EC 2.4.1.222; 299203-70-6; O-fucosylpeptide β-1,3-N-acetylglucosaminyltransferase; fringe (ambiguous). Cat No: EXWM-2451.
peptide-O-fucosyltransferase
Involved in the biosynthesis of O-fucosylated epidermal growth factor (EGF) and thrombospondin type 1 repeats. The attachment of O-linked fucose to serine or threonine occurs on EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys. Group: Enzymes. Synonyms: GDP-L-fucose:polypeptide fucosyltransferase; GDP-fucose protein O-fucosyltransferase; GDP-fucose:polypeptide fucosyltransferase. Enzyme Commission Number: EC 2.4.1.221. CAS No. 9033-8-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2450; peptide-O-fucosyltransferase; EC 2.4.1.221; 9033-08-3; GDP-L-fucose:polypeptide fucosyltransferase; GDP-fucose protein O-fucosyltransferase; GDP-fucose:polypeptide fucosyltransferase. Cat No: EXWM-2450.
1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-a-L-fucopyranose - an organic molecule possessing diverse biological activities, has been regarded as a promising candidate for developing new-generation therapeutic agents. The structural resemblance of this compound to fucose renders it an ideal candidate for targeting fucose-associated physiological processes that underlie pathological conditions like inflammation and tumor metastasis. Its potential as a therapeutic agent has been widely explored, primarily owing to its ability to modulate fucosylation-mediated interactions between cell surface glycoconjugates and their cognate ligands, thereby exhibiting encouraging results. Synonyms: 2-Fluoro-a-L-fucose triacetate; 1,3,4-Tri-O-acetyl-2,6-dideoxy-2-fluoro-a-L-galactopyranose. CAS No. 74554-12-4. Molecular formula: C12H17FO7. Mole weight: 292.26.
1,6-α-L-fucosidase
The enzyme from Aspergillus niger does not act on 1,2-, 1,3-, or 1,4-L-fucosyl linkages. Group: Enzymes. Synonyms: α-L-fucosidase; 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. Enzyme Commission Number: EC 3.2.1.127. CAS No. 102925-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3810; 1,6-α-L-fucosidase; EC 3.2.1.127; 102925-35-9; α-L-fucosidase; 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. Cat No: EXWM-3810.
2,3,4-Tri-O-acetyl-a-L-fucopyranosyl bromide
2,3,4-Tri-O-acetyl-a-L-fucopyranosyl bromide, a glycosylating agent utilized in organic synthesis, has considerable promise in medicinal chemistry. Its application in the fabrication of fucose-infused medications and inquiry on the correlation between fucosylation, cancer, and inflammation, substantiates its potential in this field. Synonyms: Acetobromofucose 2,3,4-Tri-O-acetyl-6-deoxy-L-galactopyranosyl bromide. CAS No. 16741-27-8. Molecular formula: C12H17BrO7. Mole weight: 353.16.
2,3,4-Tri-O-acetyl-b-L-fucopyranosyl dibenzyl phosphate, a derivative of phosphorylated fucoside, is often employed in the production of glycolipids and glycoproteins. This compound displays a remarkable ability to selectively suppress specific fucosylated glycoenzymes that fuel tumor growth and metastasis, marking it as an excellent candidate for potential cancer therapies. Synonyms: [(2S,3R,4R,5S,6R)-4,5-Diacetyloxy-6-bis(phenylmethoxy)phosphoryloxy-2-methyloxan-3-yl] acetate; 6-Deoxy-beta-L-galactopyranose 2,3,4-triacetate 1-[bis(phenylmethyl) phosphate]; (2R,3S,4R,5R,6S)-2-((bis(benzyloxy)phosphoryl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate; SCHEMBL9300189; |A-L-Galactopyranose, 6-deoxy-, 2,3,4-triacetate 1-[bis(phenylmethyl) phosphate]; A889013; beta-L-Galactopyranose, 6-deoxy-, 2,3,4-triacetate 1-[bis(phenylmethyl) phosphate]; (2R,3S,4R,5R,6S)-4,5-bis(acetyloxy)-2-{[bis(benzyloxy)phosphoryl]oxy}-6-methyloxan-3-yl acetate. CAS No. 128473-05-2. Molecular formula: C26H31O11P. Mole weight: 550.49.
2,6-Dideoxy-2-fluoro-L-galactopyranose (α, β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro- β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H11FO4, Molecular Weight: 166.15. US Biological Life Sciences.
2,6-Dideoxy-2-fluoro-L-galactopyranose (α,β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro-β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Synonyms: 2-Deoxy-2-fluoro-L-fucose. Molecular formula: C6H11FO4. Mole weight: 166.15.
2-Acetamido-2-deoxy-3-O-(α-L-fucopyranosyl)-D-glucopyranose is a highly significant compound within the biomedical sector, employed as a facilitator in the research and development of targeted drugs and therapeutic methodologies tailored to cellular receptors and signaling pathways. Synonyms: 3-Fucosyl GlcNAc 2-(Acetylamino)-2-deoxy-3-O-(6-deoxy-a-L-galactopyranosyl)-D-glucopyranose Fuc-a-1,3-GlcNAc. CAS No. 52630-68-9. Molecular formula: C14H25NO10. Mole weight: 367.35.
2-Amino-2-deoxy-D-fucose
2-Amino-2-deoxy-D-fucose is a highly significant constituent serving as an antecedent in the intricate amalgamation of polysaccharides acknowledged as fucosyl-glycans. These glycans, instrumental in cell identification, immunological retort, and inflammatory processes, assume a paramount status. Synonyms: D-Galactose, 2-amino-2,6-dideoxy-; 2-Amino-2,6-dideoxy-D-galactose; D-Fucose, 2-amino-2-deoxy-; Galactose, 2-amino-2,6-dideoxy-, D-; D-Fucosamine. Grades: ≥95%. CAS No. 6931-59-5. Molecular formula: C6H13NO4. Mole weight: 163.17.
2-Amino-2-deoxy-L-arabinose hydrochloride
2-Amino-2-deoxy-L-arabinose hydrochloride, a pharmacological compound, has gained attention for its antitumor and immunomodulatory properties. Through its potent inhibition of fucosyltransferase (FUT), a key enzyme involved in the formation of Lewis X antigen, it shows promise as a therapeutic agent for an array of malignancies and immunological conditions. The multifaceted mechanisms by which 2-Amino-2-deoxy-L-arabinose hydrochloride exerts its effects requires further study, but the potential for groundbreaking advancements in the field of oncology and immunotherapy cannot be denied. Synonyms: (2R,3R,4S)-2-Amino-3,4,5-trihydroxypentanal hydrochloride; 65982-16-3. CAS No. 65982-16-3. Molecular formula: C5H11NO4.HCl. Mole weight: 185.61.
2-Amino-2-deoxy-L-fucose
2-Amino-2-deoxy-L-fucose, a monosaccharide of paramount significance, intricately participates in the inherent complexity of glycan biosynthesis. Its versatile attributes serve as a substrate for fucosyltransferases, inducing the production of fucosylated glycans, a heterogeneous group of biomolecules, meticulously regulating critical biological processes, including cell adhesion and signal transduction. Researchers have also investigated its potential therapeutic applications in ameliorating cancer and inflammatory diseases. Synonyms: 2-Amino-2,6-dideoxy-L-galactose L-Fucosamine. CAS No. 7577-62-0. Molecular formula: C6H13NO4. Mole weight: 163.17.
2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)- β-D-glucopyranosyl azide 3,4,6-Triacetate is used to synthesize core fucosylated N-glycans and asparagine-linked glycan chains, stereoselectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 102816-24-0. Pack Sizes: 500mg, 5g. Molecular Formula: C20H20N4O9, Molecular Weight: 460.39. US Biological Life Sciences.
Worldwide
2-Deoxy-D-galactose
2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1949-89-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-131892.
2-Naphthyl a-L-fucopyranoside
2-Naphthyl a-L-fucopyranoside is a critical compound extensively used in biomedical research. It serves as a substrate for enzymes like fucosidase and alpha-L-fucosidase, enabling the analysis of their activity. Additionally, this product plays a vital role in studying diseases associated with abnormal fucosylation, such as cancer and congenital disorders. Synonyms: b-Nap-a-L-Fuc b-Naphthyl-a-L-fucopyranoside. CAS No. 63503-05-9. Molecular formula: C16H18O5. Mole weight: 290.31.
2-O-α-L-Fucopyranosyl-D-galactose
2-O-α-L-Fucopyranosyl-D-galactose is a compound used in the research of neurodegenerative disorders, such as Alzheimer's disease, by inhibiting the formation of beta-amyloid plaques. Uses: A new type of β-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan. Synonyms: 2-O-(6-Deoxy-α-L-galactopyranosyl)-D-galactose; Blood Group H Disaccharide; Fuc1-α-2Gal. Grades: 97%. CAS No. 24656-24-4. Molecular formula: C12H22O10. Mole weight: 326.3.
4,6-O-Benzylidene Lactosamine 6-Sulfate Pentaacetate Triethylamine Salt
An intermediate in the preparation of α1,3-L-Fucosyltransferase acceptors. Synonyms: 2-(Acetylamino)-2-deoxy-4-O-(4,6-O-benzylidene-di-o-acetyl-β-D-galactopyranosyl)-tri-O-acetyl-D-glucose 6-(Hydrogen Sulfate) Triethylamine Salt. Molecular formula: C35H51N2O18S. Mole weight: 819.85.
4-Nitrophenyl 2-O-(2,3,4-tri-O-acetyl-b-L-fucopyranosyl)-6-O-benzoyl-a-D-galactopyranoside is a compound used in biomedical research. It is commonly utilized as a substrate in enzymatic assays to study fucosyltransferase activity. This compound aids in the investigation of glycan biosynthesis and can be employed in the development of potential anti-cancer or anti-viral drugs targeting fucose-containing glycans. Molecular formula: C31H35NO16. Mole weight: 677.61.
4-Nitrophenyl 2-O-(b-L-fucopyranosyl)-b-D-galactopyranoside is a crucial compound employed in biomedicine. It acts as a substrate for fucosidase enzymes, facilitating the study of diseases associated with aberrant fucosylation. Additionally, it can be used in the development and evaluation of potential drugs targeting fucosidases and in the synthesis of novel carbohydrate-based therapeutics for various diseases. Synonyms: Fuc-b-1-2-Gal-b-PNP. CAS No. 77640-21-2. Molecular formula: C18H25NO12. Mole weight: 447.39.
4-Nitrophenyl b-D-fucopyranoside
4-Nitrophenyl b-D-fucopyranoside is a biochemical compound widely used in the biomedical industry acting as a substrate for enzymatic assays to study the activity of fucosyltransferases. It provides valuable insights into enzyme kinetics, drug development and understanding diseases related to alterations in fucose metabolism or glycosylation patterns. Synonyms: PNP-b-D-Fuc. CAS No. 1226-39-7. Molecular formula: C12H15NO7. Mole weight: 285.25.
A1F N-Glycan
A1F N-Glycan, the versatile biomolecule employed by the biomedical industry, is the key player in the in-depth scrutiny and diagnosis of diverse disorders - think cancer, Alzheimer's, and rheumatoid arthritis. Its multifaceted involvement in cell signaling pathways has made it a go-to diagnostic marker in countless clinical settings. Furthermore, the therapeutic potential of A1F N-Glycan has not gone unexploited; it forms the crux of several drug formulations aimed at combating these afflictions. Synonyms: Monosialo (2,6), fucosylated biantennary (A1F); A1F glycan; FA2G2S1 Glycan; Mono-sialylated, galactosylated, core-fucosylated, bi-antennary N-linked glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), mono-sialyl-bis(galactosyl-N-acetylglucosaminyl); NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2Fuc. Grades: ≥90%. CAS No. 571188-30-2. Molecular formula: C79H131N5O58. Mole weight: 2078.88.
A2FB N-Glycan
A2FB N-Glycan is an indispensable compound in the biomedical field, playing a significant role in elucidating and deciphering the intricate N-glycosylation profiles discernible in diverse pharmaceuticals and ailments. Synonyms: sialyl, fucosylated, bisected biantennary N-linked glycan.
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