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| Product | Description | |
|---|---|---|
| Gabapentin | Gabapentin. CAS No: 60142-96-3 |  Sarchem Laboratories New Jersey NJ |
| Gabapentin | Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60142-96-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-A0057. |  |
| Gabapentin 98+% | Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1- (Aminomethyl) cyclohexaneacetic Acid, Neurontin, GOE-3450. Grades: USP. CAS No. 60142-96-3. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. |  Worldwide |
| Gabapentin-d4 (1- (Aminomethyl) cyclohexaneacetic Acid-d4, Neurontin-d4, GOE-3450-d4) | Amino acid structurally related to g-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1- (Aminomethyl) cyclohexaneacetic Acid-d4;Neurontin-d4; GOE-3450-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Gabapentine Impurity 7 | Gabapentine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36269-57-5. Molecular Formula: C10H18O2. Mole Weight: 170.25. Catalog: APB36269575. |  |
| Gabapentine Impurity 8 | Gabapentine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103985-51-9. Molecular Formula: C10H18O2. Mole Weight: 170.25. Catalog: APB103985519. | |
| Gabapentine Impurity 9 | Gabapentine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 63562-01-6. Molecular Formula: C10H20ClNO2. Mole Weight: 221.73. Catalog: APB63562016. | |
| Gabapentin enacarbil | Gabapentin enacarbil (XP-13512) is a prodrug of Gabapentin (HY-A0057) designed to be absorbed throughout the intestine by high-capacity nutrient transporters. Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin enacarbil can be used for the study of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XP-13512. CAS No. 478296-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-16216. | |
| Gabapentin EP impurity A | Gabapentin EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64744-50-9. Molecular Formula: C9H15NO. Mole Weight: 153.23. Catalog: APB64744509. | |
| Gabapentin EP impurity B | Gabapentin EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133481-09-1. Molecular Formula: C9H13NO2. Mole Weight: 167.21. Catalog: APB133481091. | |
| Gabapentin EP impurity D | Gabapentin EP impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1076198-17-8. Molecular Formula: C18H29NO3. Mole Weight: 307.43. Catalog: APB1076198178. | |
| Gabapentin EP impurity E | Gabapentin EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67950-95-2. Molecular Formula: C9H14O4. Mole Weight: 186.21. Catalog: APB67950952. | |
| Gabapentin EP impurity G | Gabapentin EP impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1500558-49-5. Molecular Formula: C10H19NO2. Mole Weight: 185.27. Catalog: APB1500558495. | |
| Gabapentin Ethyl Ester Hydrochloride | Protected Gabapentin. Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-(Aminomethyl)-cyclohexaneacetic Acid Ethyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 60175-04-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Gabapentin hydrochloride | Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome. Synonyms: Gabapentin Hydrochloride; Gabapentin HCl; 60142-95-2; Gabapentin (hydrochloride); Gabarone; 1-(Aminomethyl)cyclohexaneacetic acid HCl; Cyclohexaneacetic acid, 1-(aminomethyl)-, hydrochloride; N0PY5N5AFW; 2-(1-(aminomethyl)cyclohexyl)acetic acid hydrochloride; 60142-95-2 (HCl); 2-[1-(aminomethyl)cyclohexyl]acetic acid hydrochloride; UNII-N0PY5N5AFW; 1-(Aminomethyl)cyclohexaneacetic acid hydrochloride; Neurontin HCl. Grades: >98%. CAS No. 60142-95-2. Molecular formula: C9H17NO2.HCl. Mole weight: 207.7. |  |
| Gabapentin hydrochloride | Gabapentin hydrochloride is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60142-95-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-A0057A. | |
| Gabapentin Impurity 1 | Gabapentin Impurity 1 is a piperidinedione derivative. Synonyms: 2,4-Dioxo-3-Azaspiro[5.5]Undecane-1,5-Dicarbonitrile; 8,10-Diketo-9-Azaspiro[5.5]Undecane-7,11-Dicarbonitrile; Nsc169442; α,α'-Dicyano-1,1-cyclohexanediacetamide; NSC 408757. Grades: > 95%. CAS No. 4355-15-1. Molecular formula: C12H13N3O2. Mole weight: 231.26. | |
| Gabapentin Impurity 2 | Gabapentin Impurity 2 is a pervasive compound employed in the realm of biomedicine. Its broad-spectrum utility manifests in navigating diverse neurological predicaments, embracing the likes of epilepsy and neuropathic pain. An augmenting agent, Gabapentin Impurity 2, intensifies the therapeutic prowess of its well-renowned counterpart, Gabapentin, extensively harnessed as an antiepileptic remedy. Synonyms: 3,3-Pentamethyleneglutaric Acid; Cyclohexane-1,1'-diacetic acid; 1,1-Cyclohexanediacetic acid; Cyclohexanediacetic acid; 1,1-Bis(carboxymethyl)cyclohexane; NSC 169443; NSC 39839. Grades: > 95%. CAS No. 4355-11-7. Molecular formula: C10H16O4. Mole weight: 200.24. | |
| Gabapentin Impurity 2 | Gabapentin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. CAS No. 4355-15-1. Molecular Formula: C12H13N3O2. Mole Weight: 231.25. Catalog: APB4355151. | |
| Gabapentin Impurity (2-(3-Oxobutyl)-2-Azaspiro-(4,5)-decan-3-one) | Grades: > 95%. Molecular formula: C13H21NO2. Mole weight: 223.32. | |
| Gabapentin Impurity 3 | Gabapentin Impurity 3 is a chemical with potential use for biochemical research, especially in the field of neurobiology. It is Gabapentin intermediate. Synonyms: 3,3-Pentamethyleneglutarimide; 1,1-Cyclohexane diacetimide; 3,3-Pentamethylene Glutarimide; 2,4-Dioxo-3-azaspiro[5.5]undecane; 1,1-Cyclohexanediacetimide; 3-Azaspiro[5.5]undecane-2,4-dione; NSC 400093. Grades: > 95%. CAS No. 1130-32-1. Molecular formula: C10H15NO2. Mole weight: 181.24. | |
| Gabapentin impurity 5 | Gabapentin impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1990449-64-3. Molecular Formula: C21H35NO11. Mole Weight: 477.51. Catalog: APB1990449643. | |
| Gabapentin Impurity G | Grades: > 95%. Molecular formula: C10H19NO2. Mole weight: 185.27. | |
| Gabapentin Lactam (3-Azaspiro-[4,5]-decan-2-one) | Gabapentin Lactam reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease. It opens mitochondrial ATP-dependent potassium channels. Group: Biochemicals. Alternative Names: 3-Azaspiro-[4,5]-decan-2-one. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Gabapentin Related Bis-nitrile | An intermediate in the synthesis of Gabapentin. Group: Biochemicals. Alternative Names: 1-Cyanocyclohexane acetonitrile; 1-Cyanomethyl-1-cyclohexanenitrile. Grades: Highly Purified. CAS No. 4172-99-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Gabapentin Related Compound A | Gabapentin Lactam (Gabapentin EP Impurity A; Gabapentin USP Related Compound A) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease. It opens mitochondrial ATP-dependent potassium channels. Group: Biochemicals. Alternative Names: 3-Azaspiro-[4,5]decan-3-one; Gabapentin lactam; USP Gabapentin Related Compound A; Gabapentin EP Impurity A; Gabapentin USP Related Compound A. Grades: Highly Purified. CAS No. 64744-50-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C?H??NO, Molecular Weight: 153.22. US Biological Life Sciences. | Worldwide |
| Gabapentin Related Compound B | A Gabapentin analogue for treatment of neurological disorders. Group: Biochemicals. Alternative Names: 1-Cyanocyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 133481-09-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gabapentin Related Compound D | A Gabapentin analogue. Group: Biochemicals. Alternative Names: [1- (3-Oxo-2-aza-spiro[4, 5]dec-2-ylmethyl) cyclohexyl]acetic Acid; 1- [ (3-oxo-2-azaspiro [4. 5] dec-2-yl) methyl] cyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 1076198-17-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Gabapentin related compound e | Gabapentin related compound e. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Carboxycyclohexaneacetic Acid;Gabapentin Related Compound E;NSC 9082;NSC 90823;Gabapentin USP RC E;1-(CarboxyMethyl)cyclohexane-1-carboxylic acid;Gabapentin iMpurity E;Gabapentin EP Impurity E. Product Category: Heterocyclic Organic Compound. CAS No. 67950-95-2. Molecular formula: C9H14O4. Mole weight: 0. Density: 1.246. Product ID: ACM67950952. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gabapentin Related Compound E | A Gabapentin analogue. Group: Biochemicals. Alternative Names: 1-Carboxycyclohexane acetic Acid; NSC 90823. Grades: Highly Purified. CAS No. 67950-95-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gabapentin Related Compound E | Gabapentin Related Compound E is a Gabapentin analogue. Synonyms: 1-Carboxycyclohexaneacetic acid; NSC 90823; Gabapentin USP RC E; 1-(CarboxyMethyl)cyclohexane-1-carboxylic acid. Grades: > 95%. CAS No. 67950-95-2. Molecular formula: C9H14O4. Mole weight: 186.21. | |
| Gabapentin Related Material B | Gabapentin Related Material B is a Gabapentin analogue for treatment of neurological disorders. Synonyms: (1-cyanocyclohexyl)acetic acid; 2-(1-Cyanocyclohexyl)acetic acid; Gabapentin USP RC B; 1-Cyanocyclohexaneacetic Acid; USP Gabapentin Related Compound B. Grades: > 95%. CAS No. 133481-09-1. Molecular formula: C9H13NO2. Mole weight: 167.21. | |
| Gabapentin Related Material D | Gabapentin Related Material D is a Gabapentin analogue. Synonyms: 1-[(3-Oxo-2-azaspiro[4.5]dec-2-yl)methyl]cyclohexaneacetic acid; [1-(3-Oxo-2-aza-spiro[4,5]dec-2-ylmethyl)cyclohexyl]acetic Acid; USP Gabapentin Related Compound D; Gabapentin USP RC D. Grades: > 95%. CAS No. 1076198-17-8. Molecular formula: C18H29NO3. Mole weight: 307.44. | |
| Boc-Gabapentin | Boc-Gabapentin. Group: Biochemicals. Alternative Names: Boc-Gpn; Boc-1-aminomethyl-cyclohexane acetic acid. Grades: Highly Purified. CAS No. 227626-60-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Boc-Gabapentin ≥95% (HPLC) | Boc-Gabapentin ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g, 5g. US Biological Life Sciences. | Worldwide |
| Fmoc-Gabapentin | Fmoc-Gabapentin. Group: Biochemicals. Alternative Names: Fmoc-Gpn; Fmoc-1-aminomethyl-cyclohexane acetic acid. Grades: Highly Purified. CAS No. 882847-19-0. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Fmoc-Gabapentin | Synonyms: 2-[1-[ (9H-fluoren-9-ylmethoxycarbonylamino) methyl]cyclohexyl]acetic acid; [1-((Fmoc-amino)methyl)cyclohexyl]acetic acid; [1-[(9h-fluoren-9-ylmethoxycarbonylamino)-methyl]-cyclohexyl]-acetic acid; Fmoc-1-aminomethyl-cyclohexane acetic acid. Grades: ≥ 95% (HPLC). CAS No. 882847-19-0. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
| Fmoc-Gabapentin ≥95% (HPLC) | Fmoc-Gabapentin ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| N-rt-Butyloxycarbonyl Gabapentin | Protected Gabapentin. Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-[[[ (1, 1-Dimethylethoxy) carbonyl]amino]methyl]-cyclohexaneacetic Acid; 2- [1- [ (tert-Butoxycarbonylamino) methyl] cyclohexyl] acetic Acid; [1- (tert-Butoxycarbonylamino methyl ) cyclohexyl] acetic Acid. Grades: Highly Purified. CAS No. 227626-60-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 1-(2-Aminoethyl)-cyclohexaneacetic Acid Acetic Acid Salt | 1-(2-Aminoethyl)-cyclohexaneacetic Acid Acetic Acid Salt is a Gabapentin (G117250) Impurity. Gabapentin EP Impurity G. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H23NO4, Molecular Weight: 245.32. US Biological Life Sciences. | Worldwide |
| 1- [ [ (2-Methyl-1-oxopropyl) amino] methyl] cyclohexaneacetic Acid | 1- [ [ (2-Methyl-1-oxopropyl) amino] methyl] cyclohexaneacetic Acid is derived from Gabapentin (G117250), which is an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Also, it is an impurity formed in the synthesis of [1-[[ (α -isobutanoyloxyethoxy) carbonyl]aminomethyl]-1-cyclohexane Acetic Acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1281568-83-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H23NO3, Molecular Weight: 241.33. US Biological Life Sciences. | Worldwide |
| 1- (3-Oxo-2-aza-spiro[4, 5]dec-2-ylmethyl) cyclohexaneethanol | Intermediate in the preparation of Gabapentin analogues. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1- (3-Oxo-2-aza-spiro[4, 5]dec-2-ylmethyl) cyclohexaneethanol Benzyl Ether | Intermediate in the preparation of Gabapentin analogues. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-butylpyrrolidin-2-one | 1-Butylpyrrolidin-2-one is a pharmaceutical intermediate used in the synthesis of drugs such as gabapentin and levetiracetam, which are used to treat neuropathic pain and epilepsy. Synonyms: 1-Butyl-2-pyrrolidinone; 1-Butyl-2-pyrrolidone. Grades: 95%. CAS No. 3470-98-2. Molecular formula: C8H15NO. Mole weight: 141.21. | |
| 1-cyanocyclohexaneacetic acid | 1-cyanocyclohexaneacetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Cyanocyclohexane acetic acid;Gabapentin related compound B. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 133481-09-1. Molecular formula: C9H13NO2. Mole weight: 167.21. Product ID: ACM133481091. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1-(Isobutyryloxy) Ethyl 3-Oxo-2-azaspiro[4,5]decane-2-carboxylate | 1-(Isobutyryloxy) Ethyl 3-Oxo-2-azaspiro[4,5]decane-2-carboxylate is derived from Gabapentin (G117250), which is an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C16H25NO5, Molecular Weight: 311.37. US Biological Life Sciences. | Worldwide |
| 1- (Nitromethyl) cyclohexaneacetic Acid-d4 Methyl Ester | Intermediate in the preparation of labeled Gabapentin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1- (Nitromethyl) cyclohexaneacetic Acid Ethyl Ester | Gabapentin Intermediate. Group: Biochemicals. Grades: Highly Purified. CAS No. 133938-45-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1- (Nitromethyl) cyclohexane-d6-acetic Acid Ethyl Ester | 1- (Nitromethyl) cyclohexane-d6-acetic Acid Ethyl Ester is the labeled analogue of 1- (Nitromethyl) cyclohexaneacetic Acid Ethyl Ester (N496585), a Gabapentin (G117250) Intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C11H13D6NO4, Molecular Weight: 235.31. US Biological Life Sciences. | Worldwide |
| 2-(3-Oxobutyl)-2-azaspiro[4.5]decan-3-one | 2-(3-Oxobutyl)-2-azaspiro[4.5]decan-3-one is a derivative of Gabapentin Lactam (G117275); a compound that reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease. Gabapentin Lactam also opens mitochondrial ATP-dependent potassium channels. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C13H21NO2, Molecular Weight: 223.31. US Biological Life Sciences. | Worldwide |
| 2-(3-Oxobutyl)-2-azaspiro[4.5]decan-3-one-d6 | 2-(3-Oxobutyl)-2-azaspiro[4.5]decan-3-one-d6 is the isotope labelled analog of 2-(3-Oxobutyl)-2-azaspiro[4.5]decan-3-one (O848400); a derivative of Gabapentin Lactam (G117275) which is a compound that reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease. Gabapentin Lactam also opens mitochondrial ATP-dependent potassium channels. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H15D6NO2, Molecular Weight: 229.35. US Biological Life Sciences. | Worldwide |
| 2-Cyano-2-cyclohexylideneacetic Acid Ethyl Ester | Used in the preparation of Gabapentin analogue. Group: Biochemicals. Alternative Names: Ethyl Cyanocyclohexylidene acetate; NSC 10726. Grades: Highly Purified. CAS No. 6802-76-2. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-? ( (Cyclohexanecarbony?l) ?oxy) ?acetic Acid | 2-? ( (Cyclohexanecarbony?l) ?oxy) ?acetic Acid (Gabapentin EP Impurity E; Gabapentin USP Related Compound E) is a metabolite of Gabapentin (G117250), amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 667465-00-1. Pack Sizes: 50mg, 500mg. Molecular Formula: C9H14O4, Molecular Weight: 186.21. US Biological Life Sciences. | Worldwide |
| 3,3-Pentamethylene Glutarimide | Gabapentin intermediate. Group: Biochemicals. Alternative Names: 2,4-Dioxo-3-azaspiro[5.5]undecane; 1, 1-Cyclohexane diacetimide; 3-Azaspiro[5.5]undecane-2,4-dione; NSC 400093. Grades: Highly Purified. CAS No. 1130-32-1. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 4,4-Pentamethylene-2-pyrrolidinone | Gabapentin Related Compound A, a cell permeable compound, has been reported to reduce oxygen glucose deprivation-induced [3H]glutamate release in rat ischemia hippocampal slices. It reduces protein aggregates and improves motor performance in a transgenic. Synonyms: 2-azaspiro[4.5]decan-3-one. Grades: 96 %. CAS No. 64744-50-9. Molecular formula: C9H15NO. Mole weight: 153.22. | |
| Gebapentine USP | (3-Methacryoyloxypropyl)-trimethoxysilane; 1-(Aminomethyl)cyclohexaneacetic acid; gabapentin; Neurontin. antidepressant. Grades: USP. CAS No. 60142-96-3. Product ID: 8-01590. Molecular formula: C9H17NO2. Mole weight: 171.23. Purity: ³98%. Reference: J. Clin. Psychiatry 63,:331, 2002. |  |
| Mirogabalin | This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which related to related to drugs such as gabapentin and pregabalin. Mirogabalin binds to the α2δ calcium channels (1 and 2) and was estimated to be much more potent than pregabalin. In Nov 2015, a Japanese company named Daiichi Sankyo plans a phase III trial for Postherpetic neuralgia and Neuropathic pain (in patients with diabetic peripheral neuropathy and renal impairment) in Japan. In May 2016, Pharmacokinetics and adverse data from a phase I trial in volunteers presented at the 35th Annual Scientific Meeting of the American Pain Society. Uses: Treatment of diabetic peripheral neuropathic pain. Synonyms: 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, DS-5565,CAS#1138245-21-2 ( Mirogabalin besylate). Grades: 98%. CAS No. 1138245-13-2. Molecular formula: C12H19NO2. Mole weight: 209.29. | |
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