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100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H10O5. CAS No. 446-72-0. Prepack ID 24388232-100mg. Molecular Weight 270.24. See USA prepack pricing.
Genistein
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H10O5. CAS No. 446-72-0. Prepack ID 24388232-1g. Molecular Weight 270.24. See USA prepack pricing.
Genistein
Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Inhibitor of mammalian DNA topoisomerase II. Anticancer agent, inducing cell cycle arrest and apoptosis. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers. Potent alpha-glucosidase inhibitor. Anthelmintic. Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities. Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Stimulator of autophagy vacuolization. Antioxidant. TRAIL sensitizer. Acts as an agonist at the GPR30 receptor. DNA methyltransferase inhibitor. Genistein exhibits synergistic antibacterial effects on MRSA. Group: Biochemicals. Alternative Names: NSC 36586; Baichanin A; Differenol A; 4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 446-72-0. Pack Sizes: 10mg, 50mg, 250mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Genistein
Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. Uses: Antitumor agent. Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; Differenol A. Grades: >98%. CAS No. 446-72-0. Molecular formula: C15H10O5. Mole weight: 270.24.
Genistein
Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR ) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis , the cell cycle, and angiogenesis and inhibiting metastasis. Uses: Scientific research. Group: Natural products. Alternative Names: NPI 031L. CAS No. 446-72-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14596.
Genistein
Genistein - Product ID: NST-10-7. Category: Flavonoids. Alternative Names: 4',5,7-Trihydroxyisoflavone. Purity: 98%. Test method: HPLC. CAS No. 446-72-0. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White to beige coloured Powder. Molecular formula: C15H10O5. Mole weight: 270.24. Storage: +2 +8 °C.
Genistein
Having property of female hormone and antiestrogenic Having oxidation resistance effect Control activity of PTK Control activity of topoisomeraseII. Alternative Names: Sophoricol. CAS No. 446-72-0. Molecular formula: C15H10O5. Mole weight: 270.24. Appearance: Off-white powder. Purity: 0.98. IUPACName: 5,7-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one. Canonical SMILES: C1=CC (=CC=C1C2=COC3=CC (=CC (=C3C2=O)O)O)O. Density: 1.2319 g/cm³. Catalog: ACM446720.
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50-2.6uM). Also i. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyisoflavone-2,3,5,6-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50-2.6uM). Also i. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyisoflavone-2,6-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Genistein (4',5,7-Trihydroxyisoflavone)
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50-2.6uM). Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyisoflavone. Grades: Highly Purified. CAS No. 446-72-0. Pack Sizes: 1g, 10g. US Biological Life Sciences.
Worldwide
Genistein 7,4'-di-O- β-D-glucopyranoside
Genistein 7,4'-di-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 36190-98-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Genistein 7,4'-di-O-β-D-glucopyranoside
Genistein 7,4'-di-O-β-D-glucopyranoside is a comopund of the flavonoid class found in the aerial parts of Lupinus hartwegi. Synonyms: Genistein 4',7-di-β-D-glucopyranoside; 7-(β-D-Glucopyranosyloxy)-3-[4-(β-D-glucopyranosyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one; Genistein 4',7-diglucoside. Grades: >98%. CAS No. 36190-98-4. Molecular formula: C27H30O15. Mole weight: 594.52.
A derivative of Genistein. Inhibitor. Isoflavone derivative found in soy-based food products. Group: Biochemicals. Alternative Names: Genistein 7-O-Glucoside; Genistein-7-b-O-Glucopyranoside;7-(b-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Genistoside; NSC 5112. Grades: Highly Purified. CAS No. 529-59-9. Pack Sizes: 25mg, 100mg. US Biological Life Sciences.
Worldwide
Genistein-7-sulfate 4- β-D-glucuronide Disodium Salt
Genistein-7-sulfate 4- β-D-glucuronide is a metabolite of Genistein (G350000), a compound that exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
2,3,4-Tri-O-acetyl-6-methyl- β-D-glucopyranuronosyl Genistein Glucuronide Methyl Ester Triacetate is the protected metabolite of Genistein (G350000) which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C41H42O23. US Biological Life Sciences.
Protected Genistein. Group: Biochemicals. Alternative Names: 5- (Acetyloxy) -3-[4- (acetyloxy) phenyl]-7-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-4H-1-Benzopyran-4-one. Grades: Highly Purified. CAS No. 470666-99-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
4',5-Di-O-acetyl genistein
4',5-Di-O-acetyl genistein. Group: Biochemicals. Alternative Names: 5-(acetyloxy)-3-[4-(acetyloxy)phenyl]-7-hydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 656229-81-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H14O7. US Biological Life Sciences.
Worldwide
4,5-Di-O-acetyl Genistein
Protected Genistein. Group: Biochemicals. Alternative Names: 5-(acetyloxy)-3-[4-(acetyloxy)phenyl]-7-hydroxy-. Grades: Highly Purified. CAS No. 656229-81-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
4'-O-tert-Butyldimethylsilyl genistein
4'-O-tert-Butyldimethylsilyl genistein. Group: Biochemicals. Alternative Names: 3- [4- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] phenyl] -5, 7-dihydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 470666-97-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C21H24O5Si. US Biological Life Sciences.
Worldwide
4-O-tert-Butyldimethylsilyl Genistein
Protected Genistein. Group: Biochemicals. Alternative Names: 3- [4- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] phenyl] -5, 7-dihydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 470666-97-8. Pack Sizes: 25mg. US Biological Life Sciences.
Benzyloxy Genistein 2,3,4-Triacetate- β-D-glucopyranuronic Acid Methyl Ester is an protected intermediate of Genistein (G350000) metabolite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2-hydroxyisoflavanone synthase
Requires cytochrome P-450. The reaction involves the migration of the 2-phenyl group of the flavanone to the 3-position of the isoflavanone. The 2-hydroxyl group is derived from the oxygen molecule. EC 4.2.1.105, 2-hydroxyisoflavanone dehydratase, acts on the products with loss of water and formation of genistein and daidzein, respectively. Group: Enzymes. Synonyms: CYP93C; IFS; isoflavonoid synthase. Enzyme Commission Number: EC 1.14.13.136. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0735; 2-hydroxyisoflavanone synthase; EC 1.14.13.136; CYP93C; IFS; isoflavonoid synthase. Cat No: EXWM-0735.
Negative control for genistein. Group: Biochemicals. Grades: Highly Purified. CAS No. 486-66-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Daidzein Diglucuronide
Daidzein Diglucuronide is a metabolite of Daidzein (D103500) which is an inactive analog of Genistein (G350000). Genistein blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 335591-27-0. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C27H26O16. US Biological Life Sciences.
Worldwide
flavonoid 4'-O-methyltransferase
The enzyme catalyses the 4'-methylation of naringenin. In vitro it catalyses the 4'-methylation of apigenin, quercetin, daidzein and genistein. Group: Enzymes. Synonyms: SOMT-2; 4'-hydroxyisoflavone methyltransferase. Enzyme Commission Number: EC 2.1.1.231. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1834; flavonoid 4'-O-methyltransferase; EC 2.1.1.231; SOMT-2; 4'-hydroxyisoflavone methyltransferase. Cat No: EXWM-1834.
Genistin
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside. CAS No. 529-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0595.
A heme-thiolate protein (P-450). Acts on daidzein, formononetin and genistein. EC 1.14.13.53, 4'-methoxyisoflavone 2'-hydroxylase, has the same reaction but is more specific as it requires a 4'-methoxyisoflavone. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Enzyme Commission Number: EC 1.14.13.89. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0897; isoflavone 2'-hydroxylase; EC 1.14.13.89; 110183-49-8; isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Cat No: EXWM-0897.
isoflavone 4'-O-methyltransferase
Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol. Group: Enzymes. Synonyms: 4'-hydroxyisoflavone methyltransferase; isoflavone methyltransferase; isoflavone O-methyltransferase. Enzyme Commission Number: EC 2.1.1.46. CAS No. 55071-80-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1950; isoflavone 4'-O-methyltransferase; EC 2.1.1.46; 55071-80-2; 4'-hydroxyisoflavone methyltransferase; isoflavone methyltransferase; isoflavone O-methyltransferase. Cat No: EXWM-1950.
isoflavone 7-O-glucosyltransferase
The 4'-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4'-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins. Group: Enzymes. Synonyms: uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.170. CAS No. 97089-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2395; isoflavone 7-O-glucosyltransferase; EC 2.4.1.170; 97089-62-8; uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Cat No: EXWM-2395.
isoflavone 7-O-methyltransferase
The enzyme from alfalfa can methylate daidzein, genistein and 6,7,4'-trihydroxyisoflavone but not flavones or flavanones. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.150. CAS No. 136111-54-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1746; isoflavone 7-O-methyltransferase; EC 2.1.1.150; 136111-54-1. Cat No: EXWM-1746.
kaempferol 4'-O-methyltransferase
The enzyme acts on the hydroxy group in the 4'-position of some flavones, flavanones and isoflavones. Kaempferol, apigenin and kaempferol triglucoside are substrates, as is genistein, which reacts more slowly. Compounds with an hydroxy group in the 3' and 4' positions, such as quercetin and eriodictyol, do not act as substrates. Similar to EC 2.1.1.75, apigenin 4'-O-methyltransferase and EC 2.1.1.83, 3,7-dimethylquercetin 4'-O-methyltransferase. Group: Enzymes. Synonyms: S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase; F 4'-OMT. Enzyme Commission Number: EC 2.1.1.155. CAS No. 80747-20-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1751; kaempferol 4'-O-methyltransferase; EC 2.1.1.155; 80747-20-2; S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase; F 4'-OMT. Cat No: EXWM-1751.
KM11060
KM11060 is a mutated F508del cystic fibrosis transmembrane conductance regulator (CFTR) corrector. KM11060 is an analog of sildenafil, which restores a function of the F508del mutated CFTR chloride channel. KM11060 appears to be more potent than sildenafil, forskolin, and genistein. Synonyms: KM11060; KM-11060; KM 11060. Grades: 98%. CAS No. 774549-97-2. Molecular formula: C19H17Cl2N3O2S. Mole weight: 422.324.
Kudzu Root Extract (Standard)
Kudzu root has been known for centuries in traditional Chinese medicine as ge-gen. The first written mention of the plant as a medicine is in the ancient herbal text of Shen Nong (about A.D.100). In traditional Chinese medicine, kudzu root is used in prescriptions for the treatment of thirst, headache, and stiff neck with pain due to high blood pressure. It is also recommended for allergies, migraine headaches, inadequate measles eruptions in children, and diarrhea It is also used in modern Chinese medicine as a treatment for angina pectoris. Applications: Kudzu root extract is used as remedy for diaphoretic,antispasmodic,muscle relaxant,antipyretic.kudzu root extract is also used for fevers caused by heat in colds and influenza and for stiff neck and shoulders. Group: Others. CAS No. Puerarin: 3681-99-0Genistein: 446-72-0Daidzin: 552-66-9Daidzein: 486-66-8. Purity: 40.0% Isoflavones UV/HPLC. Mole weight: Puerarin: 416.37Genistein: 270.23Daidzin: 416.38Daidzein: 254.23. Kudzu Root Extract (Standard); Puerarin: 3681-99-0Genistein: 446-72-0Daidzin: 552-66-9Daidzein: 486-66-8; Puerarin: C21H20O9Genistein: C15H10O5Daidzin: C21H20O9Daidzein: C10H15O4. Cat No: EXTW-008.
Sophoricoside
Sophoricoside. Group: Biochemicals. Alternative Names: Genistein 4?-glucoside. Grades: Plant Grade. CAS No. 152-95-4. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences.
Worldwide
Sophoricoside
Sophoricoside - Product ID: NST-10-40. Category: Flavonoids. Alternative Names: Genistein-4'-O-glucoside. Purity: 98%. Test method: HPLC. CAS No. 152-95-4. Pack Sizes: 10g, 20g, 50g, 100g. Appearance: White to beige coloured Powder. Molecular formula: C21H20O10. Mole weight: 432.38. Storage: +2 +8 °C.
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