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Ginkgobiloba extract a natural product isolated from Ginkgobiloba, and can be used for Atherosclerosis and cardiovascular study [1]. Uses: Scientific research. Group: Natural products. CAS No. 90045-36-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N12060.
GinkgoBiloba Extract
Ginkgobiloba extract is prepared from the leaves of Maidenhair Tree after Adiantum, which is a unique species of tree with no close living relatives. Ginkgobiloba leaf extract is used for the treatment of numerous conditions, many of which are under scientific investigation. The most powerful effect of ginkgobiloba extract is on the circulating system. Ginkgobiloba extract can be used to treat respiratory problems such as asthma and bronchitis. Group: Others. Mole weight: 408.4. GinkgoBiloba Extract; GinkgoBiloba Linn. Cat No: EXTC-009.
GinkgoBiloba Leaf Extract
1.Ginkgobiloba leaf extract is an effective anti-oxidant. 2.Ginkgobiloba leaf extract can be used for anti-cancer and preventing cancer. 3.Ginkgobiloba leaf extract can promot cerebral blood circulation and cellular metabolism. 4.Ginkgobiloba leaf extract has the function of lowering blood pressure and high blood fat. 5.Ginkgobiloba leaf extract is tonifying kidney and nourishing brain, whitening and anti-wrinkle. 6.Ginkgobiloba leaf extract is effective on dilating blood vessels, promoting blood circulation and enhancing immunity. Group: Material of cosmetics. Alternative Names: GinkgoBiloba Leaf Extract. CAS No. 90045-36-6. Appearance: Yellow brown fine powder. Catalog: ACM90045366.
3-O-{2-O-[6-O-(p-hydroxyl-E-coumaroyl)-glucosyl]-(1-2)rhamnosyl kaempferol is a flavonoid compound isolated from Ginkgobiloba L. Grades: > 98%. Molecular formula: C36H36O17. Mole weight: 740.66.
Amentoflavone
Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgobiloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone. Uses: Cytochrome p-450 cyp2c9 inhibitors. Synonyms: 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 3''',8-Biflavone, 4',4''',5,5'',7,7''-hexahydroxy-; 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Ginkgetin, didemethyl-; Amenthoflavone; I3',II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin. Grades: >98%. CAS No. 1617-53-4. Molecular formula: C30H18O10. Mole weight: 538.46.
beta-D-Fructopyranose
Fructose, isolated from the leaves of Ginkgobiloba L, is transported into neocortical cells, including nerve terminals, and that it is metabolized and thereby detoxified primarily through hexokinase activity. High-Fructose intake induces nonalcoholic fatty liver disease (NAFLD) and chronic intermittent hypobaric hypoxia (CIHH) has beneficial effects on the body. Synonyms: beta-D-fructopyranose; Fructopyranose; FRUCTOSE HPLC; S(-)-FRUCTOSE; FRUCTOPYRANOSE,BETA-D-; (2R,3S,4R,5R)-2-(Hydroxymethyl)oxane-2,3,4,5-tetrol; Fructosteril; Frutabs. Grades: >98%. CAS No. 7660-25-5. Molecular formula: C6H12O6. Mole weight: 180.16.
Bilobalide
Bilobalide, a sesquiterpene trilactone constituent of Ginkgobiloba , inhibits the NMDA-induced efflux of choline with an IC 50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Bilobalide. CAS No. 33570-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0076.
Bilobalide
Bilobalide, a sesquiterpene trilactone constituent of Ginkgobiloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons. Group: Inhibitors. Alternative Names: (-)-Bilobalide. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.3. Purity: 0.98. Canonical SMILES: CC (C) (C)[C@@]1 (C[C@H]2[C@@]3 ([C@]14[C@H] (C (=O)O[C@H]4OC3=O)O)CC (=O)O2)O. Catalog: ACM33570046.
Ginkbilobin
Ginkbilobin is a novel antifungal protein from Ginkgobiloba seeds with sequence similarity to embryo-abundant protein. The protein, designated ginkbilobin, exerted potent antifungal activity against a variety of fungi, including Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum, Rhizoctonia solani, and Coprinus comatus. Ginkbilobin exhibited a moderate antibacterial action against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. It suppressed the activity of HIV-1 reverse transcriptase and the proliferation of murine splenocytes.
Ginkgolide A
Ginkgolide A (BN-52020) is an extract from in Ginkgobiloba and a g-aminobutyric acid (GABA) antagonist. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52020. CAS No. 15291-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0355.
Ginkgolide B
Ginkgolide B (BN-52021), an important active terpenoid from Ginkgobiloba leaves, is reported to increase cell viability and decrease cell apoptosis.IC50 value:Target:In vitro: Ginkgolide B (0.2 or 0.4 μg/ml) was added to the culture medium in vitro led to increases in cell viability and decreases in the number of hippocampal cells undergoing AAPH-induced apoptosis. Ginkgolide B caused a dose-related protection against dysrhythmias; the antiarrhythmic effect of ginkgolide B was comparable to that of diltiazem and superior to the activity of metoprolol. Ginkgolide B can presumably prevent the re-entry mechanism involved in the development of ischemia-induced rhythm disturbances.In vivo: Oral administration of ginkgolide B (2 mg/kg/day, p.o.) caused a significant increase in cell viability and a highly significant decrease in the numbers of both spontaneously occurring and AAPH-induced apoptoses. Group: Inhibitors. Alternative Names: 7-Deoxyginkgolide C. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.4. Appearance: White powder. Purity: 0.98. IUPACName: (1R, 3R, 6R, 7S, 8S, 10R, 11R, 12R, 13S, 16S, 17R)-8-tert-butyl-6, 12, 17-trihydroxy-16-methyl-2, 4, 14, 19-tetraoxahexacyclo[8.7.2.01, 11.03, 7.07, 11.013, 17]nonadecane-5, 15, 18-trione. Canonical SMILES: C[C@@H]1C (=O)O[C@@H]2[C@]1 ([C@@]34C (=O)O[C@H]5[C@]3 ([C@H]2O)[C@@]6 ([C@@H] (C5)C (C) (C)C)[C@H] (C (=O)O[C@H]6O4)O)O. Catalog: ACM15291777.
Ginkgolide C
Ginkgolide C is a flavone isolated from Ginkgobiloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52022. CAS No. 15291-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0785.
Ginkgolide J
Ginkgolide J is extracted from the seed of Ginkgobiloba L. It reduces apoptotic damage in cultured chick embryonic neurons. It contributes to the antioxidant properties of G. biloba. It has the superoxide scavenging effect and neuroprotective effect. Synonyms: 7beta-hydroxyginkgolide a; BN 52024; GinkgolideA, 7-hydroxy-, (7β)-; J Ginkgoli. Grades: >98%. CAS No. 107438-79-9. Molecular formula: C20H24O10.
Isoginkgetin
Isoginkgetin isolated from the leaves of Ginkgobiloba L. Uses: Anti-tumor activity. Synonyms: 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-methoxy-5-(4-oxo-5,7-dihydroxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one. Grades: 0.975. CAS No. 548-19-6. Molecular formula: C32H22O10. Mole weight: 566.51.
Nitidine chloride
Nitidine chloride is a potent inducer of energy metabolism and has been shown to stimulate the growth of cells in tissue culture. It is also active against cancer cells, and has been shown to decrease cell proliferation, induce apoptosis, and inhibit angiogenesis. Nitidine chloride has been shown to be an inhibitor of protein synthesis by binding to the polymerase chain reaction (PCR) enzyme. Nitidine chloride can also affect cell nuclei by inhibiting DNA replication. The mechanism of action for nitidine chloride is not fully understood but may be due to its ability to bind with DNA or RNA in cells. This binding inhibits transcription and translation processes, leading to inhibition of protein synthesis and cell death. Nitidine chloride is found naturally in plants such as Ginkgobiloba and Acorus calamus. The compound can be synthesized from chloroacetamide, a natural compound that is produced by bacteria such as Corynebacterium glutamicum. Group: Other alkaloids. CAS No. 13063-04-2. Molecular formula: C21H18ClNO4. Mole weight: 383.82 g/mol. Canonical SMILES: C[N+]1=CC2=CC (=C (C=C2C3=C1C4=CC5=C (C=C4C=C3)OCO5)OC)OC. [Cl-]. Catalog: ACM13063042.
Pre-mRNA Splicing Inhibitor, Isoginkgetin
A cell-permeable, naturally isolated Ginkgobiloba biflavanoid that acts as a general pre-mRNA splicing inhibitor (ICmax=50uM in splicing assays using HeLa nuclear extract) by blocking the spliceosome-meidated splicing process at the prespliceosome/A complex stage. Isoginkgetin treatment is shown to result in growth arrest in HEK293-derived cultures in a reversible manner without affecting cell viability (33uM for 24h).217696 is a cell-permeable inhibitor of pre-mRNA splicing. Blocks spliceosome-mediated splicing process at the pre-spliceosome/A complex stage. Group: Biochemicals. Alternative Names: 8-(5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one. Grades: Highly Purified. CAS No. 548-19-6. Pack Sizes: 10mg. Molecular Formula: C??H??O??, Molecular Weight: 566.5. US Biological Life Sciences.
Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid compound isolated from Ginkgobiloba L. Grades: > 98%. Molecular formula: C36H36O18. Mole weight: 756.66.
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