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| Product | Description | |
|---|---|---|
| C2 Adamantanyl Glucosylceramide (d18:1/2:0) | C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid. It increases levels of glycosphingolipids in Vero cells at low concentrations (≤20 μM) but decreases them at high concentrations (≥40 μM). Pretreatment of microsomes with AdaGluCer increases production of adamantanyl lactosylceramide (AdaLacCer) and reduces synthesis of LacCer from exogenous GlcCer. AdaGluCer inhibits glucocerebrosidase activity in vitro in a pH-dependent manner. Synonyms: N-(1-Adamantaneacetyl) Glucosylceramide; Adamantanyl GluCer(d18:1/2:0); Adamantanyl Glucosylceramide (d18:1/2:0); AdaGluCer(d18:1/2:0). Grades: ≥98%. Molecular formula: C36H61NO8. Mole weight: 635.87. |  |
| D-threo-PDMP hydrochloride | D-threo-PDMP hydrochloride is a glucosylceramide (GlcCer) synthase inhibitor that inhibits glucosylceramide (GlcCer) and lactosylceramide (LacCer) levels in B16 melanoma cells. D-threo-PDMP hydrochloride lacks reactivity to the other two surface antigens anti-melanoma monoclonal antibodies M562 and M622 and the major histocompatibility antigen anti-H-2KbDb monoclonal antibody, so it is specific for B16 melanoma sex [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 139889-62-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116392F. |  |
| Galactosylceramide | Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation. Uses: Scientific research. Group: Signaling pathways. CAS No. 85305-88-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151240. | |
| Glucosyl-C18-sphingosine | Glucosyl-C18-sphingosine is a cytotoxic compound. Accumulation of Glucosyl-C18-sphingosine in brain and other tissues occurs in patients with Gaucher disease, which is an inherited deficiency of lysosomal glucocerebrosidase, which converts glucosylsphingosine to glucose and sphingosine. Synonyms: glucosylsphingosine; Lyso GlcCer; lyso-GlcCer; D-Glucosylsphingosine; Glucosyl sphingosine; beta-D-glucosylsphingosine; 1-glucosyl-sphing-4-enine; Glucosyl(β) Sphingosine (d18:1); (2S,3R,4E)-1-O-beta-(D-glucopyranosyl)-4-sphingenine. Grades: >99%. CAS No. 52050-17-6. Molecular formula: C24H47NO7. Mole weight: 461.63. | |
| glucosylceramidase | Also acts on glucosylsphingosine (cf. EC 3.2.1.62 glycosylceramidase). Group: Enzymes. Synonyms: psychosine hydrolase; glucosphingosine glucosylhydrolase; GlcCer-β-glucosidase; β-D-glucocerebrosidase; glucosylcerebrosidase; β-glucosylceramidase; ceramide glucosidase; glucocerebrosidase; glucosylsphingosine β-glucosidase; glucosylsphingosine β-D-glucosidase. Enzyme Commission Number: EC 3.2.1.45. CAS No. 37228-64-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3908; glucosylceramidase; EC 3.2.1.45; 37228-64-1; psychosine hydrolase; glucosphingosine glucosylhydrolase; GlcCer-β-glucosidase; β-D-glucocerebrosidase; glucosylcerebrosidase; β-glucosylceramidase; ceramide glucosidase; glucocerebrosidase; glucosylsphingosine β-glucosidase; glucosylsphingosine β-D-glucosidase. Cat No: EXWM-3908. |  |
| Glucosylceramide (Soy) | Glucosylceramide is synthesised enzymatically, by the glucosylceramide synthase-catalysed with the addition of a glucose residue to ceramide. They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species, where they comprise 5-30% of total lipids in the plant plasma membrane, and in fungi. Synonyms: Cerebroside (Soy); GlcCer(d18:2/16:0). Grades: >99%. CAS No. 497155-61-0. Molecular formula: C40H75NO9. Mole weight: 714.03. | |
| N- (n-Butyl ) deoxygalactono jirimycin | An extremely potent and selective a-D-galactosidase inhibitor. A selective inhibitior of GlcCer synthesis. Group: Biochemicals. Alternative Names: (2R,3S,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol; NBDGJ. Grades: Highly Purified. CAS No. 141206-42-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?, Molecular Weight: 219.28. US Biological Life Sciences. |  Worldwide |
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