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Glucosaminesulfate (D-Glucosaminesulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosaminesulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes [1]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Glucosaminesulfate. CAS No. 29031-19-4. Pack Sizes: 500 mg. Product ID: HY-N0487.
Glucosaminesulfate EP impurity B
Glucosaminesulfate EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13185-73-4. Molecular Formula: C12H20N2O8. Mole Weight: 320.3. Catalog: APB13185734.
Glucosaminesulfate EP impurity C
Glucosaminesulfate EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 17460-13-8. Molecular Formula: C12H20N2O7. Mole Weight: 304.3. Catalog: APB17460138.
GlucosamineSulfate Potassium
GlucosamineSulfate Potassium - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
It appears as a component of heparin and heparin sulfate. Synonyms: D-Glucosamine-2-N-sulfate sodium salt; D-Glucosamine 2-sulfate sodium salt; 2-Deoxy-2-sulfamino-D-glucopyranose sodium salt; GlcN-2S sodium salt; 2-Deoxy-2-sulfoamino-D-glucose Sodium Salt; N-Sulfoglucosamine Sodium Salt. Grades: ≥95%. CAS No. 38899-05-7. Molecular formula: C6H12NNaO8S. Mole weight: 281.22.
D-Glucosamine-2-N,3-O,6-O-trisulfate sodium salt
It is the predominant 3-O-sulfated unit found in the antithrombin binding site in porcine mucosal heparin. Synonyms: 2-Deoxy-2-(sulfoamino)-D-glucose 3,6-bis(hydrogen sulfate) trisodium salt; D-Glucosamine N2,3,6-trisulfate sodium salt. CAS No. 157297-02-4. Molecular formula: C6H10NNa3O14S3. Mole weight: 485.31.
D-Glucosamine 6-sulfate has been shown as an activator of ribozyme GlmS. Applications: A ribozyme glms activator. Group: Coenzymes. Synonyms: GlcN-6S; D-Glucosamine-6-O-sulphate. CAS No. 91674-26-9. Purity: ≥99%. Mole weight: 259.23. Appearance: Powder. Form: Solid. GlcN-6S; D-Glucosamine-6-O-sulphate; D-Glucosamine 6-sulfate; 91674-26-9. Cat No: COEC-112.
D-Glucosaminesulfate
Glucosaminesulfate is present in mucopolysaccharides and in polysaccharides found in bacteria, fungi, higher plants. Glucosaminesulfate has environmental antibacterial activity. Uses: Antiarthritic/antibacterial. Synonyms: Chitosamine Sulphate; 2-Amino-2-deoxy-D-glucose sulphate. Grades: >98%. CAS No. 29031-19-4. Molecular formula: C6H13NO5 H2SO4. Mole weight: 277.25.
D-Glucosaminesulfate 2NaCl
Cas No. 38899-05-07.
Glucosamine 6-sulfate
Glucosamine 6-sulfate (GlcN6P) is an organic cofactor that splits phosphodiester bonds. Glucosamine 6-sulfate plays a variety of catalytic roles in glmS ribozymes [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: GlcN6P; D-Glucosamine-6-sulfate. CAS No. 91674-26-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W009439.
This enzyme differs from the other [heparan sulfate]-glucosamine 3-sulfotransferases [EC 2.8.2.29 ([heparan sulfate]-glucosamine 3-sulfotransferase 2) and EC 2.8.2.30 ([heparan sulfate]-glucosamine 3-sulfotransferase 3)] by being the most selective for a precursor of the antithrombin-binding site. It has a minimal acceptor sequence of: ? GlcNAc6S? GlcA? GlcN2S*+/-6S? IdoA2S? GlcN2S?, the asterisk marking the target (symbols as in 2-Carb-38) using +/- to mean the presence or absence of a substituent, and > to separate a predominant structure from a minor one. Thus Glc(N2S > NAc) means a residue of glucosamine where the N carries a sulfo group mainly but occasionally a...sulfotransferase; glucosaminyl 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase; isoform/isozyme 1 (3-OST-1, HS3ST1). Enzyme Commission Number: EC 2.8.2.23. CAS No. 183257-54-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3382; [heparan sulfate]-glucosamine 3-sulfotransferase 1; EC 2.8.2.23; 183257-54-7; heparin-glucosamine 3-O-sulfotransferase; 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase; glucosaminyl 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase; isoform/isozyme 1 (3-OST-1, HS3ST1). Cat No: EXWM-3382.
This enzyme sulfates the residues marked with an asterisk in sequences containing at least ? IdoA2S? GlcN*? or ? GlcA2S? GlcN*? (symbols as in 2-Carb-38). Preference for GlcN2S vs. unmodified GlcN has not yet been established. Additional structural features are presumably required for substrate recognition, since the 3-O-sulfated residue is of low abundance, whereas the above IdoA-containing sequence is quite abundant. This enzyme differs from the other [heparan sulfate]-glucosamine 3-sulfotransferases by modifying selected glucosamine residues preceded by GlcA2S; EC 2.8.2.23 ([heparan sulfate]-glucosamine 3-sulfotransferase 1) prefers GlcA or IdoA, whereas EC 2.8.2.30 ([heparan sulfate]-glucosamine 3-sulfotransferase 3) prefers IdoA2S. Group: Enzymes. Synonyms: glucosaminyl 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase; isoform/isozyme 2 (3-OST-2, HS3ST2). Enzyme Commission Number: EC 2.8.2.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3388; [heparan sulfate]-glucosamine 3-sulfotransferase 2; EC 2.8.2.29; glucosaminyl 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase; isoform/isozyme 2 (3-OST-2, HS3ST2). Cat No: EXWM-3388.
Two major substrates contain the tetrasaccharides: ? undetermined 2-sulfo-uronic acid? GlcN2S? IdoA2S? GlcN*? and ? undetermined 2-sulfo-uronic acid? GlcN2S? IdoA2S? GlcN6S*? (symbols as in 2-Carb-38) with modification of the N-unsubstituted glucosamine residue (shown with an asterisk). Modification of selected sequences containing N-sulfo-glucosamine residues cannot yet be excluded. The 3-O-sulfated heparan sulfate can be utilized by Herpes simplex virus type 1 as an entry receptor to infect the target cells. There are two isozymes, known as 3-OST-3A and 3-OST-3B, which have identical catalytic domains but are encoded by different mammalian genes. The specificity of this enzyme differs from that of the other [heparan sulfate]-glucosamine 3-sulfotransferases. It is inefficient at modifying precursors of the antithrombin binding site [in contrast to EC 2.8.2.23 ([heparan sulfate]-glucosamine 3-sulfotransferase 1)] and it does not modify glucosamine preceded by GlcA2S [unlike EC 2.8.2.29 ([heparan sulfate]-glucosamine 3-sulfotransferase 2)]. Group: Enzymes. Enzyme Commission Number: EC 2.8.2.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3390; [heparan sulfate]-glucosamine 3-sulfotransferase 3; EC 2.8.2.30. Cat No: EXWM-3390.
[heparan sulfate]-glucosamine N-sulfotransferase
The enzyme also catalyses the sulfation of chondroitin 4-sulfate and dermatan sulfate, but to a much more limited extent. Group: Enzymes. Synonyms: heparin N-sulfotransferase; 3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase; PAPS:N-desulfoheparin sulfotransferase; PAPS:DSH sulfotransferase; N-HSST; N-heparan sulfate sulfotransferase; heparan sulfate N-deacetylase/N-sulfotransferase; heparan sulfate 2-N-sulfotransferase; heparan sulfate N-sulfotransferase; heparan sulfate. Enzyme Commission Number: EC 2.8.2.8. CAS No. 9026-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3402; [heparan sulfate]-glucosamine N-sulfotransferase; EC 2.8.2.8; 9026-75-9; heparin N-sulfotransferase; 3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase; PAPS:N-desulfoheparin sulfotransferase; PAPS:DSH sulfotransferase; N-HSST; N-heparan sulfate sulfotransferase; heparan sulfate N-deacetylase/N-sulfotransferase; heparan sulfate 2-N-sulfotransferase; heparan sulfate N-sulfotransferase; heparan sulfate sulfotransferase; N-desulfoheparin sulfotransferase; desulfoheparin sulfotransferase; 3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase; heparitin sulfotransferase; 3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase. Cat No: EXWM-3402.
N-Acetyl-D-glucosamine-3-6-di-O-sulfate sodium salt
It is a mixed anomer. Synonyms: Disodium 2-acetamido-2-deoxy-3,6-di-O-sulfonato-D-glucose; D-Glucose, 2-(acetylamino)-2-deoxy-, 3,6-bis(hydrogen sulfate), sodium salt (1:2). Grades: ≥95%. CAS No. 481649-96-1. Molecular formula: C8H13NNa2O12S2. Mole weight: 425.30.
N-Acetyl-D-Glucosamine (Glucosaminesulfate EP impurity A)
N-Acetyl-D-Glucosamine (Glucosaminesulfate EP impurity A). Uses: For analytical and research use. Group: Impurity standards. CAS No. 7512-17-6. Molecular Formula: C8H15NO6. Mole Weight: 221.21. Catalog: APB7512176.
2-Acetamido-2-deoxy-D-glucopyranose 6-sulphate sodium salt
It also occurs in heparin and glycoproteins. Synonyms: N-Acetyl-D-glucosamine-6-O-sulfate sodium salt; 2-(Acetylamino)-2-deoxy-D-glucose 6-(Hydrogen Sulfate) Monosodium Salt; GlcNAc-6S sodium salt. Grades: ≥95%. CAS No. 108321-79-5. Molecular formula: C8H14NNaO9S. Mole weight: 323.25.
D-Glucosamine-2-N,3-O-disulphate disodium salt
It is the residue found in the antithrombin binding site in heparin. Synonyms: D-Glucosamine N2,3-disulfate disodium salt; 2-Deoxy-2-sulfamino-D-glucopyranose-3-sulfate disodium salt; [(3R,4R,5R,6R)-2,5-dihydroxy-6-(hydroxymethyl)-3-(sulfonatoamino)oxan-4-yl] sulfate disodium. Grades: ≥95%. CAS No. 112898-34-7. Molecular formula: C6H11NO11S2Na2. Mole weight: 383.25.
D-Glucosamine-3,4,6-tri-O-sulphate trisodium salt
It is a mixed anomer. Synonyms: D-glucosamine 3,4,6-trisulfate sodium; 2-Amino-2-deoxy-D-glucose 3,4,6-tris(hydrogen sulfate) sodium salt; Sodium (2R,3R,4R,5R)-5-amino-2-hydroxy-6-oxohexane-1,3,4-triyl tris(sulfate); Trisodium 2-amino-2-deoxy-3,4,6-tri-O-sulfonato-D-glucopyranose. Grades: ≥95%. CAS No. 157297-03-5. Molecular formula: C6H10NO14S3Na3. Mole weight: 485.31.
D-Glucosamine-3-O-sulphate
It's part of the heparin antithrombin binding site. Synonyms: 3-O-Sulfateglucosamine; glucosamine 3-O-sulfate; D-Glucose, 2-amino-2-deoxy-, 3-(hydrogen sulfate); D-Glucosamine 3-sulfate; 2-Amino-2-deoxy-D-glucose 3-sulfate. Grades: ≥95%. CAS No. 76330-20-6. Molecular formula: C6H13NO8S. Mole weight: 259.23.
D-Glucosamine-6-O-sulphate
It is a component of heparin, heparin sulfate, keratin sulfate, and cell surface glycoconjugates. Synonyms: D-Glucosamine 6-Sulfate; GLCN-6S; {[(2R,3S,4R,5R)-5-amino-2,3,4-trihydroxy-6-oxohexyl]oxy}sulfonic acid; 2-Amino-2-deoxy-6-O-sulfo-D-glucose; D-Glucose, 2-amino-2-deoxy-, 6-(hydrogen sulfate). Grades: ≥95%. CAS No. 91674-26-9. Molecular formula: C6H13NO8S. Mole weight: 259.23.
Brings about the acetylation of glucosamine groups of heparan sulfate and heparin from which the sulfate has been removed. Also acts on heparin. Not identical with EC 2.3.1.3 glucosamine N-acetyltransferase or EC 2.3.1.4 glucosamine-phosphate N-acetyltransferase. Group: Enzymes. Synonyms: acetyl-CoA:α-glucosaminide N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.78. CAS No. 79955-83-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2258; heparan-α-glucosaminide N-acetyltransferase; EC 2.3.1.78; 79955-83-2; acetyl-CoA:α-glucosaminide N-acetyltransferase. Cat No: EXWM-2258.
heparanase
Heparanase cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Heparanase-1 cuts macromolecular heparin into fragments of 5000-20000 Da. The enzyme cleaves the heparan sulfate glycosaminoglycans from proteoglycan core proteins and degrades them to small oligosaccharides. Inside cells, the enzyme is important for the normal catabolism of heparan sulfate proteoglycans, generating glycosaminoglycan fragments that are then transported to lysosomes and completely degraded. When secreted, heparanase degrades basement membrane heparan sulfate glycosaminoglycans at sites of injury or inflammation, allowing extravasion of immune cells into nonvascular spaces and releasing factors that regulate cell proliferation and angiogenesis. Group: Enzymes. Synonyms: Hpa1 heparanase; Hpa1; heparanase 1; heparanase-1; C1A heparanase; HPSE. Enzyme Commission Number: EC 3.2.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3848; heparanase; EC 3.2.1.166; Hpa1 heparanase; Hpa1; heparanase 1; heparanase-1; C1A heparanase; HPSE. Cat No: EXWM-3848.
Heparinase III
The enzyme cleaves 1-4 linkages between N-acetylated or N-sulphated glucosamine and glucuronic acid residues. It is only active towards heparan sulfate in the low sulphated zone and does not cleave heparin or low molecular weight heparins. Highly sulfated zones are resistant to it and activity towards iduronic acid is very low. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Heparinase III from Flavobacterium heparinum; Heparin Lyase III; Heparitinase I; Heparan monosulfate lyase; Heparin sulfate eliminase; Heparin-sulfate lyase. CAS No. 37290-86-1. Mole weight: 70.8 kDa.
Heparin derived disaccharide sodium salt
Heparin derived disaccharide sodium salt is a biomedical product used in the research of blood clotting disorders. This sodium salt compound is derived from heparin, a drug commonly used to prevent and study deep vein thrombosand pulmonary embolism. Synonyms: 2-Deoxy-2-sulfoamino-6-O-sulfo-4-O-(2-O-sulfo-a-L-idopyranuronosyl)-a-D-glucopyranose; 4-O-(a-L-Idopyranosyluronic acid 2-sulfate)-D-glucosamine 2,6-disulfate. CAS No. 98797-50-3. Molecular formula: C12H15NO19S3 Na4. Mole weight: 665.4.
Heparin Sodium
Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosaminesulfate, in the human body is secreted by mast cells and naturally exists in the blood. Heparin sodium Chemicalbook can prevent platelet aggregation and destruction, inhibit the transformation of fibrinogen into fibrin monomer, inhibit the formation of thrombin and counter the already formed thrombin, prevent the transformation of prothrombin into thrombin and antithrombin. Synonyms: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. CAS No. 9041-8-1. Product ID: PAP-0071. Molecular formula: (C12H16NS2Na3)20. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Heparin Sodium; PAP-0071; Cardiovascular; (C12H16NS2Na3)20; 9041-08-1. Standard: CP. Chemical Name: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. Grade: Pharmaceutical Grade. Solubility: H2O: 50 mg/mL, clear, faintly yellow. Storage: 2-8°C. Melting Point: >181°C (dec.). Product Description: Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosaminesulfate, in the human body is secreted by ma
heparin-sulfate lyase
Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Group: Enzymes. Synonyms: heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II. Enzyme Commission Number: EC 4.2.2.8. CAS No. 37290-86-1. Heparinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5107; heparin-sulfate lyase; EC 4.2.2.8; 37290-86-1; heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II. Cat No: EXWM-5107.
Heparin-sulfate lyase from Bacteroides thetaiotaomicron, Recombinant
Heparin-sulfate lyase is an enzyme from Bacteroides thetaiotaomicron that acts on linkages between acetyl-glucosamine and uronate. Group: Enzymes. Synonyms: heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; EC 4.2.2.8. Enzyme Commission Number: EC 4.2.2.8. CAS No. 37290-86-1. Purity: >90% as judged by SDS-PAGE. Heparinase. Mole weight: 76.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides thetaiotaomicron. heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; EC 4.2.2.8. Cat No: NATE-1550.
heparosan-N-sulfate-glucuronate 5-epimerase
The enzyme acts on D-glucosyluronate residues in N-sulfated heparosan polymers, converting them to L-iduronate, thus modifying the polymer to heparan-N-sulfate. The enzyme requires that at least the N-acetylglucosamine residue linked to C-4 of the substrate has been deacetylated and N-sulfated, and activity is highest with fully N-sulfated substrate. It does not act on glucuronate residues that are O-sulfated or are adjacent to N-acetylglucosamine residues that are O-sulfated at the 6 position. Thus the epimerization from D-glucuronate to L-iduronate occurs after N-sulfation of glucosamine residues but before O-sulfation. Not identical with EC 5.1.3.19 chondroitin-glucuronate 5-epimerase or with EC 5.1.3.36, heparosan-glucuronate 5-epimerase. Group: Enzymes. Synonyms: heparosan epimerase; heparosan-N-sulfate-D-gl. Enzyme Commission Number: EC 5.1.3.17. CAS No. 112567-86-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5402; heparosan-N-sulfate-glucuronate 5-epimerase; EC 5.1.3.17; 112567-86-9; heparosan epimerase; heparosan-N-sulfate-D-glucuronosyl 5-epimerase; C-5 uronosyl epimerase; polyglucuronate epimerase; D-glucuronyl C-5 epimerase; poly[(1,4)-β-D-glucuronosyl-(1,4)-N-sulfo-α-D-glucosaminyl] glucurono-5-epimerase. Cat No: EXWM-5402.
Keratanase II from Bacillus circulans, Recombinant
Keratansae II hydrolyzes 1, 3-beta-glucosaminidic linkages to galactose in keratan sulfate. On cleavage, the enzyme requires the sulfate at 6-0 position of the participating glucosamine, but acts independently of the sulfate at 6-0 position of the galactose linked to the glucosamine. Applications: Used in the screening and diagnosis of morquio a syndrome (mps iva). validation of an lc-ms/ms assay for detecting relevant disaccharides from keratan sulfate as a biomarker for morquio a syndrome. Group: Enzymes. Purity: >90%. Endo-β-galactosidase. Storage: Reconstituted protein can be stored at 4°C or in small aliquots at -20°C or below. Avoid repeated freeze-thaw cycles. Form: Powder. Source: E. coli. Species: Bacillus circulans. Endo-β-galactosidase; endo-β-galactosidase; keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase; Keratanase II. Cat No: NATE-1618.
Native Bovine β-N-Acetylglucosaminidase
This enzyme, sometimes called β-N-acetylhexosaminidase, is reported to liberate terminal β-linked N-acetylglucosamine and N-acetylgalactosamine from a variety of substrates. The activity of β-N-actylglucosaminidase may be determined with the chromogenic substrate p-nitrophenyl-N-acetyl-β-D-glucosaminide. β-N-actylglucosaminidase hydrolyzes the terminal nonreducing N-acetyl-D-hexosamine residues. This enzyme contains two predominant isozymes, Hex A, a heterodimer, and Hex B, a homodimer. N-acetylglucosamine, acetamide, N-2-acetamido-2-deoyglucosylamine, N-acetylnojirimycin, and N-acetyldeoxynojirmycin are known inhibitors. Applications: Bovine ki...idase A; N-acetylhexosaminidase; β-D-hexosaminidase; 9012-33-3; EC 3.2.1.52. Enzyme Commission Number: EC 3.2.1.52. CAS No. 9012-33-3. β-N-Acetylhexosaminidase. Activity: 10-50 units/mg protein. Storage: 2-8°C. Form: ammonium sulfate suspension. Suspension in 3.2 M (NH4)2SO4, pH approx. 6.0. Source: Bovine kidney. Species: Bovine. hexosaminidase; β-acetylaminodeoxyhexosidase; N-acetyl-β-D-hexosaminidase; N-acetyl-beta-hexosaminidase; β-hexosaminidase; β-acetylhexosaminidinase; β-D-N-acetylhexosaminidase; β-N-acetyl-D-hexosaminidase; β-N-acetylglucosaminidase; hexosaminidase A; N-acetylhexosaminidase; β-D-hexosaminidase;
This enzyme, sometimes called β-N-acetylhexosaminidase, is reported to liberate terminal β-linked N-acetylglucosamine and N-acetylgalactosamine from a variety of substrates. The activity of β-N-actylglucosaminidase may be determined with the chromogenic substrate p-nitrophenyl-N-acetyl-β-D-glucosaminide. β-N-actylglucosaminidase hydrolyzes the terminal nonreducing N-acetyl-D-hexosamine residues. This enzyme contains two predominant isozymes, Hex A, a heterodimer, and Hex B, a homodimer. N-acetylglucosamine, acetamide, N-2-acetamido-2-deoyglucosylamine, N-acetylnojirimycin, and N-acetyldeoxynojirmycin are known inhibitors. At ph 4.0, p-nit...ta;-acetylaminodeoxyhexosidase; N-acetyl-β-D-hexosaminidase; N-acetyl-beta-hexosaminidase; β-hexosaminidase; β-acetylhexosaminidinase; β-D-N-acetylhexosaminidase; β-N-acetyl-D-hexosaminidase; β-N-acetylglucosaminidase; hexosaminidase A; N-acetylhexosaminidase; β-D-hexosaminidase; EC 3.2.1.52; 9012-33-3. Enzyme Commission Number: EC 3.2.1.52. CAS No. 9012-33-3. β-N-Acetylhexosaminidase. Activity: > 15 units/mg protein. Storage: 2-8°C. Form: ammonium sulfate suspension. Suspension in 2.5 M (NH4)2SO4, pH 7.0. Source: Canavalia ensiformis. hexosaminidase; β-acetylaminodeoxyhexosidase; N-acetyl-β-D-hexosaminidase; N-ac
Native Flavobacterium heparinum Heparinase III
Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. In enzymology, a heparin-sulfate lyase (EC 4.2.2.8) is an enzyme that catalyzes the chemical reaction:Elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. Group: Enzymes. Synonyms: EC 4.2.2.8; Heparinase III; 37290-86-1; heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; heparin-sulfate lyase. Enzyme Commission Number: EC 4.2.2.8. CAS No. 37290-86-1. Heparinase. Mole weight: mol wt 70.8 kDa. Activity: > 100 units/mg protein (enzyme + BSA). Storage: -20°C. Source: Flavobacterium heparinum. EC 4.2.2.8; Heparinase III; 37290-86-1; heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; heparin-sulfate lyase. Cat No: NATE-0340.
Native Human β-N-Acetylglucosaminidase
This enzyme, sometimes called β-N-acetylhexosaminidase, is reported to liberate terminal β-linked N-acetylglucosamine and N-acetylgalactosamine from a variety of substrates. The activity of β-N-actylglucosaminidase may be determined with the chromogenic substrate p-nitrophenyl-N-acetyl-β-D-glucosaminide. β-N-actylglucosaminidase hydrolyzes the terminal nonreducing N-acetyl-D-hexosamine residues. This enzyme contains two predominant isozymes, Hex A, a heterodimer, and Hex B, a homodimer. N-acetylglucosamine, acetamide, N-2-acetamido-2-deoyglucosylamine, N-acetylnojirimycin, and N-acetyldeoxynojirmycin are known inhibitors. Applications: Β-n-...etylhexosaminidase; β-D-hexosaminidase; 9012-33-3; EC 3.2.1.52. Enzyme Commission Number: EC 3.2.1.52. CAS No. 9012-33-3. β-N-Acetylhexosaminidase. Activity: 6-20 units/mg protein. Storage: 2-8°C. Form: ammonium sulfate suspension. Suspension in 2.4 M (NH4)2SO4 containing 0.15 M NaCl and 0.1 M sodium phosphate, pH 6.0. Source: Human placenta. Species: Human. hexosaminidase; β-acetylaminodeoxyhexosidase; N-acetyl-β-D-hexosaminidase; N-acetyl-beta-hexosaminidase; β-hexosaminidase; β-acetylhexosaminidinase; β-D-N-acetylhexosaminidase; β-N-acetyl-D-hexosaminidase; β-N-acetylglucosaminidase; hexosaminidase A; N-acetylhexosaminidase
Native Pseudomonas sp. N-Acylhexosamine Oxidase
In enzymology, a N-acylhexosamine oxidase (EC 1.1.3.29) is an enzyme that catalyzes the chemical reaction:N-acetyl-D-glucosamine + O2<-> N-acetyl-D-glucosaminate + H2O2. Thus, the two substrates of this enzyme are N-acetyl-D-glucosamine and O2, whereas its two products are N-acetyl-D-glucosaminate and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. Group: Enzymes. Synonyms: N-acylhexosamine oxidase; EC 1.1.3.29; N-acyl-D-hexosamine oxidase; N-acyl-β-D-hexosamine:oxygen 1-oxidoreductase; N-acyl-D-hexosamine:oxygen 1-oxidoreductase. Enzyme Commission Number: EC 1.1.3.29. CAS No. 121479-58-1. N-Acylhexosamine Oxidase. Activity: > 20 units/mg protein. Storage: 2-8°C. Form: Suspension in 80% saturated ammonium sulfate. Source: Pseudomonas sp. N-acylhexosamine oxidase; EC 1.1.3.29; N-acyl-D-hexosamine oxidase; N-acyl-β-D-hexosamine:oxygen 1-oxidoreductase; N-acyl-D-hexosamine:oxygen 1-oxidoreductase. Cat No: NATE-0469.
N-Methyl-D-glucosamine
N-Methyl-D-glucosamine is a crucial compound in the biomedical sector, serving as a precursor molecule in the synthesis of chondroitin sulfate, an indispensable constituent of connective tissues. Synonyms: 2-Deoxy-2-(methylamino)-D-glucose. CAS No. 3329-30-4. Molecular formula: C7H15NO5. Mole weight: 193.20.
N-sulfoglucosamine-3-sulfatase
The enzyme from Flavobacterium heparinum also hydrolyses N-acetyl-D-glucosamine 3-O-sulfate; the mammalian enzyme acts only on the disulfated residue. Group: Enzymes. Synonyms: chondroitinsulfatase. Enzyme Commission Number: EC 3.1.6.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3748; N-sulfoglucosamine-3-sulfatase; EC 3.1.6.15; chondroitinsulfatase. Cat No: EXWM-3748.
N-Sulfo-glucosamine Potassium salt
N-Sulfo-glucosamine Potassium salt is a valuable biomedical product with potent anti-inflammatory properties used in the research of various diseases such as inflammatory disorders and joint diseases, including osteoarthritand rheumatoid arthritis. Synonyms: Potassium N-sulfoglucosamine; Potassium ((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)sulfamate; Potassium 2-deoxy-2-sulfoamino-D-glucose; Glucosamine N-sulfate potassium salt; BWD7N48R1I; D-Glucose, 2-deoxy-2-(sulfoamino)-, potassium salt (1:1); potassium; N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]sulfamate; D-Glucose, 2-deoxy-2-(sulfoamino)-, monopotassium salt; UNII-BWD7N48R1I; C6H12KNO8S; glucosaminesulfate potassium; DTXSID80185203; AKOS016009807; AS-69554; CS-0158491; 38899-05-7; GLUCOSAMINE N-SULFATE POTASSIUM [WHO-DD]; A875974; Q27274928; Potassium((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)sulfamate; POTASSIUM (2R,3R,4S,5R)-3,4,5,6-TETRAHYDROXY-2-(SULFONATOAMINO)HEXANAL; 2-Deoxy-2-sulfoamino-D-glucose potassium salt; 2-Deoxy-2-(sulfoamino)-D-glucose monopotassium salt; D-Glucose, 2-deoxy-2-(sulfoamino)-, monopotassium salt (8CI,9CI); Potassium 2-deoxy-2-sulfoamino-D-glucose. CAS No. 31284-96-5. Molecular formula: C6H12KNO8S. Mole weight: 297.33.
4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside-6-sulfate potassium salt
4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside-6-sulfate potassium salt is an indispensable compound, serving as a pivotal substrate for precise detection and quantification of sulfatase enzyme efficacy. Synonyms: 4MU-a-N-sulpho-D-glucosaminide. CAS No. 154639-35-7. Molecular formula: C18H20KNO11S. Mole weight: 497.52.
4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt
It is a fluorescent substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). Synonyms: 4-Methylumbelliferyl N-acetyl-b-D-glucosaminide-6-sulfate sodium salt; 4-Methylumbelliferyl 2-acetamido-2-deoxy-6-sulphate-b-D-glucopyranoside sodium salt; 4MU-b-D-galactoside-6-sulphate sodium salt; 4-Methylumbelliferyl-b-D-galactoside-6-sulphate sodium salt; 7-[[2-(Acetylamino)-2-deoxy-6-O-sulfo-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one Monosodium Salt. Grades: ≥95%. CAS No. 142439-99-4. Molecular formula: C18H20NNaO11S. Mole weight: 481.41.
chondroitin AC lyase
Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less well on hyaluronate. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycan source. Group: Enzymes. Synonyms: chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5104; chondroitin AC lyase; EC 4.2.2.5; 9047-57-8; chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Cat No: EXWM-5104.
chondroitin B lyase
This is the only lyase that is known to be specific for dermatan sulfate as substrate. The minimum substrate length required for catalysis is a tetrasaccharide. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycansource. Group: Enzymes. Synonyms: chondroitinase B; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5094; chondroitin B lyase; EC 4.2.2.19; 52227-83-5; chondroitinase B; ChonB; ChnB. Cat No: EXWM-5094.
D-Glucosamine-2-N,6-O-disulphate disodium salt
It is the predominant aminosugar component in heparin. Synonyms: 2-Deoxy-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) disodium salt; Disodium [ ({ (2R, 3S, 4R, 5R) -2, 3, 4-trihydroxy-6-oxo-5-[ (sulfonatooxy) amino]hexyl}peroxy) sulfonyl]oxidanide. CAS No. 202266-99-7. Molecular formula: C6H11NO11S2Na2. Mole weight: 383.26.
D-Glucosamine-3,6-di-O-sulphate sodium salt
It's part of the heparin antithrombin binding site. Synonyms: Sodium (2R,3R,4R,5R)-5-amino-2,3-dihydroxy-6-oxohexane-1,4-diyl bis(sulfate); 2-Amino-2-deoxy-D-glucose 3,6-bis(hydrogen sulfate) disodium salt. CAS No. 536741-53-4. Molecular formula: C6H11NNa2O11S2. Mole weight: 383.25.
disulfoglucosamine-6-sulfatase
May be identical with EC 3.1.6.14 N-acetylglucosamine-6-sulfatase. Group: Enzymes. Synonyms: N-sulfoglucosamine-6-sulfatase; 6,N-disulfoglucosamine 6-O-sulfohydrolase; N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Enzyme Commission Number: EC 3.1.6.11. CAS No. 37288-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3744; disulfoglucosamine-6-sulfatase; EC 3.1.6.11; 37288-32-7; N-sulfoglucosamine-6-sulfatase; 6,N-disulfoglucosamine 6-O-sulfohydrolase; N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Cat No: EXWM-3744.
keratan-sulfate endo-1,4-β-galactosidase
Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to 1,3-N-acetyl-α-D-glucosaminyl residues. Also acts on some non-sulfated oligosaccharides, but only acts on blood group substances when the 1,2-linked fucosyl residues have been removed (cf. EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase). Group: Enzymes. Synonyms: endo-β-galactosidase (ambiguous); keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.103. CAS No. 55072-01-0. Endo-β-galactosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3786; keratan-sulfate endo-1,4-β-galactosidase; EC 3.2.1.103; 55072-01-0; endo-β-galactosidase (ambiguous); keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase. Cat No: EXWM-3786.