Glucuronosyltransferase Suppliers USA
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Product | Description | |
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1-Naphthyl b-D-glucuronide sodium salt Quick inquiry Where to buy Suppliers range | 1-Naphthyl b-D-glucuronide sodium salt, an invaluable biomedicine, is employed extensively in scientific research to explore the intricate process of glucuronidation, which plays a vital role in the metabolism and elimination of a diverse array of pharmaceuticals and endogenous compounds. Acting as a versatile substrate, it facilitates the activities of glucuronosyltransferases, crucial enzymes that mediate glucuronidation reactions. Demonstrating immense utility in in vitro experiments, this product enables scientists to unravel the profound impact of glucuronidation on drug pharmacokinetics, while simultaneously facilitating the evaluation of potential drug-drug interactions. Synonyms: 1-Nap-b-D-GlcA.Na. CAS No. 83833-12-9. Molecular formula: C16H15NaO7. Mole weight: 342.28. | |
1-Pyrenyl-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester Quick inquiry Where to buy Suppliers range | 1-Pyrenyl-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a compound primarily used in studying glucuronidation, a major phase II metabolic pathway. It can serve as a substrate in assays of UDP-glucuronosyltransferase, an enzyme increasingly targeted in drug development. Molecular formula: C29H26O10. Mole weight: 534.51. | |
3'-Azido-3'-deoxythymidine β-D-glucuronide sodium salt Quick inquiry Where to buy Suppliers range | 3'-Azido-3'-deoxythymidine β-D-glucuronide is a metabolite of the nucleoside reverse transcriptase inhibitor, zidovudine, formed by direct conjugation by UDP-glucuronosyltransferase 2B7. Synonyms: AZT glucuronide; Zidovudine glucuronide. Grades: ≥95%. CAS No. 133525-01-6. Molecular formula: C16H20N5O10·Na. Mole weight: 465.4. | |
4-Methylphenyl 2,3,4-tri-O-benzyl-b-D-thioglucuronide Quick inquiry Where to buy Suppliers range | 4-Methylphenyl 2,3,4-tri-O-benzyl-b-D-thioglucuronide is an eminent biomedical compound, efficaciously thwarting the functionality of glucuronosyltransferase enzymes. It plays a pivotal role in mediating pharmaceutical metabolism and detoxification mechanisms, offering prodigious prospects for comprehensive drug exploration. Synonyms: Toluoyl 1-thio-2,3,4-tri-O-benzyl-b-D-glucuronic acid. Molecular formula: C34H34O6S. Mole weight: 570.71. | |
5-Bromo-4-chloro-1H-indol-3-yl-b-D-glucuronide Quick inquiry Where to buy Suppliers range | 5-Bromo-4-chloro-1H-indol-3-yl-b-D-glucuronide is a notable glucuronide derivation of 5-Bromo-4-chloro-1H-indole, meticulously utilized as a probe within drug metabolism studies. This compound is commonly harnessed to evaluate the engagement of glucuronidation in the metabolic processes of specific medications, or to unlock the secrets pertaining to UDP-glucuronosyltransferase enzymes within drug elimination pathways. Synonyms: X-Glucuronide X-GlcA. CAS No. 18656-89-8. Molecular formula: C14H13BrClNO7. Mole weight: 422.61. | |
Diclofenac-acyl-beta-D-glucuronide Quick inquiry Where to buy Suppliers range | Diclofenac-acyl-beta-D-glucuronide is a vital metabolite in the biotransformation of diclofenac, an NSAID, undergoing formation predominantly via liver uridine 5'-diphospho-glucuronosyltransferase enzymes. Its participation in the metabolism and elimination of diclofenac profoundly influences its pharmacokinetics and therapeutic efficacy for studying diverse inflammatory conditions. Synonyms: 1-O-[2-[(2,6-Dichlorophenyl)amino]phenylacetyl]-b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 64118-81-6. Molecular formula: C20H19Cl2NO8. Mole weight: 472.27. | |
Ethyl 2-amino-b-D-glucuronide Quick inquiry Where to buy Suppliers range | Ethyl 2-amino-beta-D-glucuronide is a remarkable compound, used for studying glucuronidation-related disorders and drug metabolism. Its multifaceted role as a substrate for UDP-glucuronosyltransferase enzymes is crucial in facilitating the conjugation of drugs and xenobiotics. Molecular formula: C8H15NO6. Mole weight: 221.21. | |
Methyl b-D-glucuronide sodium salt Quick inquiry Where to buy Suppliers range | Methyl b-D-glucuronide sodium salt is a chemical compound used in the biomedical industry for its role in drug metabolism studies. It is commonly employed as a substrate to evaluate glucuronidation reactions mediated by glucuronosyltransferase enzymes. This product aids in understanding drug metabolism and its implications in treating various diseases by facilitating the study of drug elimination pathways. Synonyms: Methyl b-D-glucuronic acid sodium salt; 1-OMe-b-D-GlcA. Na. CAS No. 134253-42-2. Molecular formula: C7H11NaO7. Mole weight: 230.15. | |
Phenyl b-D-thioglucuronide Quick inquiry Where to buy Suppliers range | Phenyl b-D-thioglucuronide, an invaluable compound in the biomedical industry, stands at the forefront of drug metabolism studies and hepatic glucuronidation research. As a substrate for glucuronosyltransferase enzymes, this compound diligently unravels the intricate web of drug-drug interactions and illuminates the identities of drugs undergoing glucuronidation. Synonyms: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-phenylsulfanyloxane-2-carboxylic acid; Phenyl 1-thio-beta-D-glucopyranosiduronic acid; FYJ. CAS No. 26399-82-6. Molecular formula: C12H14O6S. Mole weight: 286.30. | |
Raltegravir Potassium Salt Quick inquiry Where to buy Suppliers range | Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents. Uses: Anti-hiv agents. Synonyms: MK-0518; MK 0518; MK0518; Raltegravir. Grades: 98%. CAS No. 871038-72-1. Molecular formula: C20H20FKN6O5. Mole weight: 482.514. |