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Glutarimide is an important part of many compounds displaying biological activity. Glutarimide is promising for research of anemia, multiple myeloma and cycloheximide [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1121-89-7. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-I0466.
3,3-Pentamethylene glutarimide
3,3-Pentamethylene glutarimide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3-Pentamethylene-2-pyrrolidoinone; 3-azaspiro(5,5)undecan-2,4-dione. Product Category: Heterocyclic Organic Compound. Appearance: Solid. CAS No. 1130-32-1. Molecular formula: C10H15NO2. Mole weight: 181.23. Purity: 0.97. IUPACName: 3-azaspiro[5.5]undecane-2,4-dione. Canonical SMILES: C1CCC2(CC1)CC(=O)NC(=O)C2. Density: 1.14±0.1 g/cm3(Predicted). ECNumber: 214-459-1. Product ID: ACM1130321-1. Alfa Chemistry ISO 9001:2015 Certified.
3,3-Pentamethylene Glutarimide
Gabapentin intermediate. Group: Biochemicals. Alternative Names: 2,4-Dioxo-3-azaspiro[5.5]undecane; 1, 1-Cyclohexane diacetimide; 3-Azaspiro[5.5]undecane-2,4-dione; NSC 400093. Grades: Highly Purified. CAS No. 1130-32-1. Pack Sizes: 2.5g. US Biological Life Sciences.
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4, 4-Tetra methyl eneglutarimide
Buspirone intermediate. Group: Biochemicals. Alternative Names: 8-Azaspiro[4.5]decane-7,9-dione; 1, 1-Cyclopentane diacetimide; 3-Spirocyclopentane glutarimide; NSC 400092. Grades: Highly Purified. CAS No. 1075-89-4. Pack Sizes: 1g. US Biological Life Sciences.
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Phenglutarimide
Phenglutarimide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: phenglutarimide;GLUTARIMIDE,2-((2-DIETHYLAMINO)ETHYL)-2-PHENYL-;ATURBANE;3-[2-(Diethylamino)ethyl]-3-phenyl-2,6-piperidinedione;Aturban;Ciba-10870;Phenglutarimid;1674-96-0 (Hydrochloride). Product Category: Heterocyclic Organic Compound. CAS No. 1156-05-4. Molecular formula: C17H24N2O2. Mole weight: 288.389. Density: 1.072g/cm³. Product ID: ACM1156054. Alfa Chemistry ISO 9001:2015 Certified.
3-(2-Methyl-4-oxoquinazolin-3-yl)piperidine-2,6-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID63824, LS-72039, 2-(3,4-Dihydro-2-methyl-4-oxo-3-quinazolinyl)glutarimide, 2,6-Piperidinedione, 3-(2-methyl-4-oxo-3(4H)-quinazolinyl)-, Glutarimide, 2-(3,4-dihydro-2-methyl-4-oxo-3-quinazolinyl)-, 2-Methyl-3-(propan-1-yl-1,3-dicarboxylic acid imide)-4(3H)-quinazolinone, 69557-32-0. Product Category: Heterocyclic Organic Compound. CAS No. 69557-32-0. Molecular formula: C14H13N3O3. Mole weight: 271.271 g/mol. Purity: 0.96. IUPACName: 3-(2-methyl-4-oxoquinazolin-3-yl)piperidine-2,6-dione. Canonical SMILES: CC1=NC2=CC=CC=C2C(=O)N1C3CCC(=O)NC3=O. Density: 1.47g/cm³. Product ID: ACM69557320. Alfa Chemistry ISO 9001:2015 Certified.
3-amino-2,6-piperidinedione hydrochloride
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Synonyms: 3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl. Grades: > 99 %. CAS No. 24666-56-6. Molecular formula: C5H9ClN2O2. Mole weight: 164.59.
3-Bromopiperidin-2,6-dione
3-Bromopiperidin-2,6-dione was in reaction with sodium saccharin to synthesize glutarimides derivatives to observe their activities against Ehrlich ascites carcinoma in Swiss albino mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 62595-74-8. Pack Sizes: 5mg, 25mg. Molecular Formula: C5H6BrNO2, Molecular Weight: 192.01. US Biological Life Sciences.
4-(2-Hydroxy-5,7-dimethyl-4-oxodeca-6,8-dienyl)piperidine-2,6-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-Methylstreptimidone, Antibiotic TS 885, STREPTIMIDONE, (+)-9-METHYL, NSC 248958, CID73623, BRN 1545072, NSC248958, NCI60_001987, LS-115220, 5-21-13-00443 (Beilstein Handbook Reference), 3-(5,7-Dimethyl-4-oxo-2-hydroxy-6,8-decadienyl)glutarimide, 2,6-Piperidinedione, 4-(2-hydroxy-5,7-dimethyl-4-oxo-6,8-decadiennyl)-, 51867-94-8. Product Category: Heterocyclic Organic Compound. CAS No. 51867-94-8. Molecular formula: C17H25NO4. Mole weight: 307.385 g/mol. Purity: 0.96. IUPACName: 4-(2-hydroxy-5,7-dimethyl-4-oxodeca-6,8-dienyl)piperidine-2,6-dione. Canonical SMILES: CC=CC(=CC(C)C(=O)CC(CC1CC(=O)NC(=O)C1)O)C. Density: 1.095g/cm³. Product ID: ACM51867948. Alfa Chemistry ISO 9001:2015 Certified.
5-Hydroxy-9-methylstreptimidone
5-Hydroxy-9-methylstreptimidone is a glutarimide antibiotic produced by Streptomyces sp. HIL Y-9065403. It has a weak weeding effect. Molecular formula: C17H25NO5. Mole weight: 323.38.
9-Methylstreptimidone
9-Methylstreptimidone is a glutarimide antibiotic produced by Streptomyces sp. HIL Y-9065403. It has strong herbicidal activity. Synonyms: Antibiotic TS 885. Grades: >98%. CAS No. 51867-94-8. Molecular formula: C17H25NO4. Mole weight: 307.38.
Acetylglycinamide Impurity B
An impurity of Acetylglycinamide. Synonyms: Glutarimide; 2,6-Diketopiperidine. Grades: > 95%. CAS No. 1121-89-7. Molecular formula: C5H7NO2. Mole weight: 113.12.
Acetyloxycycloheximide
Acetyloxycycloheximide is originally isolated from Streptomyces albulus ACTT 12757. When the concentration was 0.05-0.25 mg/kg, it could inhibit sarcoma 180 in mice, and its antifungal and antiyeast activities were very weak. Synonyms: E-73 acetate; Acetoxycycloheximide; Streptovitacin E 73; NSC 32743; Antibiotic E-73; 3-(2-(5-Acetoxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide. Grades: >98%. CAS No. 2885-39-4. Molecular formula: C17H25NO6. Mole weight: 339.38.
Actiketal
Actiketal is a glutarimide antibiotic isolated from Streptomyces pulveraceus subsp. epiderstagenes. Actiketal can inhibit the incorporation of [3H] thymidine into Balb/MB cells activated by epidermal growth factor, with IC50 of 14.5 μmol/L, which is stronger than its analog Actiphenol (109.6 μmol/L), but better than epidermal statin (Epiderstatin) 3000 times weaker. CAS No. 133658-47-6. Molecular formula: C15H15NO5. Mole weight: 289.28.
Actiphenol
Actiphenol is a glutarimide antibiotic isolated from Streptomyces sp. ETH 7796. Actiphenol has an inhibitory effect on yeast. Synonyms: 3-(2-Hydroxy-3,5-dimethylphenacyl)glutarimide. CAS No. 526-02-3. Molecular formula: C15H17NO4. Mole weight: 275.30.
Benzofuran
Benzofuran is produced from coal tar. Found in tobacco smoke derived compounds, it is a carcinogen, seen to cause kidney damage. However it is also used in combination with phenolic antioxidants in meat curing. It has also recently been used in the synthesis of novel glutarimide antibiotics. Group: Biochemicals. Grades: Highly Purified. CAS No. 271-89-6. Pack Sizes: 5g, 25g. Molecular Formula: C8H6O. US Biological Life Sciences.
Worldwide
Cycloheximide
Actidione; 3-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; DL-2-Chloro Mandelic Acid, Naramycin A. histamine H1 -receptor antagonist. CAS No. 66-81-9. Product ID: 8-01585. Molecular formula: C15H23NO4. Mole weight: 281.4. Purity: >95%. Properties: white to off-white crystalline. Source :
Cycloheximide
Cycloheximide is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes, resulting in inhibition of protein synthesis leading to cell growth, cell arrest and cell death. CHX is widely used for selection of CHX resistant yeast and fungi strains; controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression; apoptosis induction or facilitation of apoptosis induction of death receptors. Group: Biochemicals. Alternative Names: 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione; 3- [2- (3, 5-Dimethyl-2-oxocyclohexyl) -2-hydroxyethyl] glutarimide; Naramycin A; Acti-Aid; Acti-dione; Acti-dione BR; Acti-dione PM; Acti-dione TGF; Actidion; CHX; Cicloheximide; FT 3422-2; NSC 185; Naramycin; Naramycin Microcapsule D 80; Naramycin NM-MCU 80; TZA; U 4527; β - [2- (3, 5-Dimethyl-2-oxocyclohexyl) -2-hydroxyethyl] glutarimide. Grades: Molecular Biology Grade. CAS No. 66-81-9. Pack Sizes: 500mg, 1g, 5g, 25g. Molecular Formula: C15H23NO4, Molecular Weight: 281.35. US Biological Life Sciences.
Worldwide
Cycloheximide Solution 50mg/ml
Cycloheximide is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes, resulting in inhibition of protein synthesis leading to cell growth, cell arrest and cell death. CHX is widely used for selection of CHX resistant yeast and fungi strains; controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression; apoptosis induction or facilitation of apoptosis induction of death receptors.Prepared from C8500 Cycloheximide. Group: Biochemicals. Alternative Names: 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione; 3- [2- (3, 5-Dimethyl-2-oxocyclohexyl) -2-hydroxyethyl] glutarimide; Naramycin A; Acti-Aid; Acti-dione; Acti-dione BR; Acti-dione PM; Acti-dione TGF; Actidion; CHX; Cicloheximide; FT 3422-2; NSC 185; Naramycin; Naramycin Microcapsule D 80; Naramycin NM-MCU 80; TZA; U 4527; β - [2- (3, 5-Dimethyl-2-oxocyclohexyl) -2-hydroxyethyl] glutarimide. Grades: Molecular Biology Grade. CAS No. 66-81-9. Pack Sizes: 20ml, 5x20ml. Molecular Formula: C15H23NO4, Molecular Weight: 281.35. US Biological Life Sciences.
Worldwide
Epiderstatin
Epiderstatin is a glutarimide antibiotic produced by Streptomyces pulveraceus sub sp. epiderstagenes. It has the activity of inhibiting the filamentous division induced by epidermal growth factor (EGF), but does not inhibit EGF-receptor kinase (EGF-receptor kinase). It has only weak antifungal activity and no antibacterial effect. Synonyms: 4-(3-(3,5-Dimethyl-2-oxopiperidin-6-ylidene)-2-oxopropyl)-2,6-piperidinedione. CAS No. 126602-16-2. Molecular formula: C15H20N2O4. Mole weight: 292.33.
Gabapentin Impurity 3
Gabapentin Impurity 3 is a chemical with potential use for biochemical research, especially in the field of neurobiology. It is Gabapentin intermediate. Synonyms: 3,3-Pentamethyleneglutarimide; 1,1-Cyclohexane diacetimide; 3,3-Pentamethylene Glutarimide; 2,4-Dioxo-3-azaspiro[5.5]undecane; 1,1-Cyclohexanediacetimide; 3-Azaspiro[5.5]undecane-2,4-dione; NSC 400093. Grades: > 95%. CAS No. 1130-32-1. Molecular formula: C10H15NO2. Mole weight: 181.24.
Glutamycin
It is produced by the strain of Aspergillus flavipes F-2090/7. It is a glutarimide antibiotic. It has anti-gram-positive bacteria, negative bacteria and fungi (individual) activity. Synonyms: Flavipucin; (-)-Flavipucin; 1-oxa-7-azaspiro[2.5]oct-5-ene-4,8-dione, 6-methyl-2-(3-methylbutanoyl)-, (2R,3R)-. CAS No. 38473-18-6. Molecular formula: C12H15NO4. Mole weight: 237.25.
Isocycloheximide
It is produced by the strain of Str. griseus. Isocycloheximide has antifungal effect, and its activity to Barbiturates is only 30% of that of actinomyces. Synonyms: D-Isocycloheximide; Caswell No. 504C; (+)-3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; Aktidion. CAS No. 6746-42-5. Molecular formula: C15H23NO4. Mole weight: 281.35.
maleimide hydrolase
Succinimide and glutarimide, and sulfur-containing cyclic imides, such as rhodanine, can also act as substrates for the enzyme from Blastobacter sp. A17p-4. The reverse, cyclization, reaction is also catalysed, but much more slowly. It has lower activity towards cyclic ureides, which are the substrates of EC 3.5.2.2, dihydropyrimidinase. Group: Enzymes. Synonyms: imidase; cyclic imide hydrolase; cyclic-imide amidohydrolase (decyclicizing) [misprint]; cyclic-imide amidohydrolase (decyclizing). Enzyme Commission Number: EC 3.5.2.16. CAS No. 9030-74-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4499; maleimide hydrolase; EC 3.5.2.16; 9030-74-4; imidase; cyclic imide hydrolase; cyclic-imide amidohydrolase (decyclicizing) [misprint]; cyclic-imide amidohydrolase (decyclizing). Cat No: EXWM-4499.
N-Acetyl-D-glutamic Acid
A glutarimide. Group: Biochemicals. Alternative Names: D-N-Acetyl Glutamic Acid. Grades: Highly Purified. CAS No. 19146-55-5. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N-Acetyl-D-Glutamic Acid
A glutarimide that shows anticonvulsant activity. Uses: A glutarimide. Synonyms: N-ACETYL-D-GLUTAMIC ACID; (R)-2-Acetamidopentanedioic acid; D-Glutamic acid, N-acetyl-; AC-D-GLU-OH; (2R)-2-acetamidopentanedioic acid; Glutamic acid, N-acetyl-; N-Acetyl-D-glutamic aicd; AC D GLU OH. Grades: ≥ 98% (HPLC). CAS No. 19146-55-5. Molecular formula: C7H11NO5. Mole weight: 189.17.
Thalidomide-OH is a ligand for E3 ligase used in PROTAC technology. Synonyms: 4-Hydroxy thalidomide; E3 ligase Ligand 2; Thalidomide-4-OH; 4-Hydroxy thalidomide, (+/-)-; 3-Hydroxythalidomide; 4-Hydroxy-thalidomide; α-(3-Hydroxy-phthalimido)-glutarimid; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione; 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione. Grades: > 95 %. CAS No. 5054-59-1. Molecular formula: C13H10N2O5. Mole weight: 274.23.
Inactone
Inactone is a bioactive molecule of 3-glutarimidyl group that inhibits large ribosomal subunit. CAS No. 487-34-3. Molecular formula: C15H21NO4. Mole weight: 279.33.
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