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| Product | Description | |
|---|---|---|
| Glutathione S-transferase | Glutathione S-transferase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 50812-37-8. Pack Sizes: 1 mg. Product ID: HY-P2961. |  |
| Glutathione S-Transferase Alpha 4 (GSTa4) Recombinant, Mouse, Positive Control Loading Buffer | Glutathione S-Transferase Alpha 4 (GSTa4) Recombinant, Mouse, Positive Control Loading Buffer. Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 1x1 vial. US Biological Life Sciences. |  Worldwide |
| Glutathione S-Transferase from E.coli, Recombinant | Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies:the cytosolic, mitochondrial, and microsomal--also known as MAPEG--proteins. Members of the GST superfamily are extremely diverse in amino acid sequence, and a large fraction of the sequences deposited in public databases are of unknown function. The Enzyme Function Initiative (EFI) is using GSTs as a model superfamily to iden...ferase. Mole weight: 26kDa. Activity: >20 units/mg. Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. Form: Sterile Filtered clear solution in Phosphate Buffered Saline pH 7.4. Source: E.coli. Species: E.coli. Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Cat No: NATE-1945. |  |
| Glutathione S-Transferase from equine liver | Synonyms: GST, Glutathione R-transferase, Glutathione S-alkenetransferase, Glutathione S-alkyltransferase, Glutathione S-aralkyltransferase, Glutathione S-aryltransferase, Glutathione S-epoxidetransferase. CAS No. 50812-37-8. |  |
| Glutathione S-Transferase from human placenta | lyophilized powder, 25-125 units/mg protein. Group: Fluorescence/luminescence spectroscopy. |  |
| Glutathione S-Transferase, Recombinant | Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies:the cytosolic, mitochondrial, and microsomalalso known as MAPEGproteins. Members of the GST superfamily are extremely diverse in amino acid sequence, and a large fraction of the sequences deposited in public databases are of unknown function. The Enzyme Function Initiative (EFI) is using GSTs as a model superfamily to identify new...erase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Enzyme Commission Number: EC 2.5.1.18. Purity: >90% (SDS-PAGE test). Mole weight: About 26kDa (SDS-PAGE detection). Activity: 30 u/mg. Appearance: White powder, lyophilized or colorless liquid. Storage: 4°C, store at -20°C for long-term preservation. Form: Freeze dried powder. Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Cat No: NATE-1141. | |
| isoprene-epoxide-glutathione S-transferase | The enzyme, characterized from the bacterium Rhodococcus sp. AD45, is involved in isoprene degradation. The enzyme can catalyse the glutathione-dependent ring opening of various epoxides, but the highest activity is with (3R)-3,4-epoxy-3-methylbut-1-ene, which is derived from isoprene by EC 1.14.13.69, alkene monooxygenase. Group: Enzymes. Synonyms: isoI (gene name). Enzyme Commission Number: EC 4.4.1.34. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5337; isoprene-epoxide-glutathione S-transferase; EC 4.4.1.34; isoI (gene name). Cat No: EXWM-5337. | |
| Microsomal glutathione S-transferase 1 isoform a (121-132) | Microsomal glutathione S-transferase 1 isoform a (121-132) is a peptide derived from Microsomal glutathione S-transferase 1 isoform a. Microsomal glutathione S-transferase 1 is a conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. And it has a wide substrate specificity. Synonyms: Microsomal GST-1 isoform a (121-132). | |
| Native Equine Glutathione S-Transferase | Glutathione S-transferases are a family of proteins that catalyze the conjugation of reduced glutathione with a variety of hydrophobic chemicals containing electrophilic centers. Group: Enzymes. Synonyms: EC 2.5.1.18; glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST; 50812-37-8. Enzyme Commission Number: EC 2.5.1.18. CAS No. 50812-37-8. Glutathione S-Transferase. Mole weight: mol wt 45-50 kDa. Activity: > 25 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing Tris and phosphate buffer salts, reduced glutathione and EDTA. Source: Equine liver. Species: Equine. EC 2.5.1.18; glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST; 50812-37-8. Cat No: NATE-0325. | |
| Native Human Glutathione S-Transferase | Glutathione S-transferases are a family of proteins that catalyze the conjugation of reduced glutathione with a variety of hydrophobic chemicals containing electrophilic centers. Group: Enzymes. Synonyms: EC 2.5.1.18; glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST; 50812-37-8. Enzyme Commission Number: EC 2.5.1.18. CAS No. 50812-37-8. Glutathione S-Transferase. Activity: 25-125 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing Tris buffer salts, reduced glutathione and EDTA. Source: Human placenta. Species: Human. EC 2.5.1.18; glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST; 50812-37-8. Cat No: NATE-0326. | |
| Native Rat Glutathione-S-Transferase | Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies:the cytosolic, mitochondrial, and microsomal--also known as MAPEG--proteins. Members of the GST superfamily are extremely diverse in amino acid sequence, and a large fraction of the sequences deposited in public databases are of unknown function. The Enzyme Function Initiative (EFI) is using GSTs as a model superfamily to identify new GST functions. Group: Enzymes. Synonyms: Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase;. Enzyme Commission Number: EC 2.5.1.18. CAS No. 50812-37-8. Purity: Purified. Glutathione S-Transferase. Activity: > 10 U/mg. Storage: -20°C. Form: Lyophilized. Source: Rat Liver. Species: Rat. Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Cat No: NATE-0327. | |
| 1,2-Dibenzoylethane | It is effective in inhibiting the in vivo mammary DMBA-DNA adduct formation. This inhibitory effect on mammary DNA adduct formation was associated with increased liver activities of glutathione S-transferase, QR, and 7-ethoxyresorufin-O-deethylase. Group: Biochemicals. Alternative Names: 1,4-Dioxo-1,4-diphenylbutane; 1,4-Diphenyl-1,4-butadione; 1,4-Diphenyl-1,4-butanedione; 2,2''-Biacetophenone; Biphenacyl; Dibenzoylethane; NSC 402168. Grades: Highly Purified. CAS No. 495-71-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 17-Chloro-androsta-5,16-dien-3 β-ol | 17-Chloro-androsta-5,16-dien-3 β-ol is a derivative of Dehydro Epiandrosterone (D229585), which is a major secretory steroidal product of the adrenal gland. Dehydro Epiandrosterone may have estrogen-or androgen-like effects depending on the hormonal milieu, and is used in the treatment of menopausal syndrome. 17-Chloro-androsta-5,16-dien-3 β-ol is also used in the synthesis of peptides and derivatives as inhibitors for Schistosoma japonica glutathione s-transferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 13592-95-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H27ClO, Molecular Weight: 306.87. US Biological Life Sciences. | Worldwide |
| 1-Chloro-2,4-dinitrobenzene | 1-Chloro-2,4-dinitrobenzene is a benzene derivative and is used in biochemical research as a substrate for glutathione S-transferase. Group: Biochemicals. Alternative Names: 1-Chloro-2,4-nitrobenzene; 2,4-Dinitro-1-chlorobenzene; 2,4-Dinitrochlorobenzene; 2,4-Dinitrophenyl chloride; 2-Chloro-1,5-dinitrobenzene; 4-Chloro-1,3-dinitrobenzene; 6-Chloro-1,3-dinitrobenzene; CDNB; DNCB; Dinitrochlorobenzene; NSC 6292; 1,3-Dinitro-4-chlorobenzene. Grades: Highly Purified. CAS No. 97-00-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminophenyl Sulfone | 2,4-Diaminophenyl Sulfone is obtained from 1-Chloro-2,4-dinitrobenzene (C365860) which is a benzene derivative and is used in biochemical research as a substrate for glutathione S-transferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 116435-84-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C12H12N2O2S, Molecular Weight: 248.3. US Biological Life Sciences. | Worldwide |
| 4-Bromoflavone | An aryl hydrocarbon hydroxylase inducer. Used as a phase II detoxifying enzymes, quninone reductase and glutathione S-transferase in cell culture and in different tissues of rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Anonaine | Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor [1]. Uses: Scientific research. Group: Natural products. CAS No. 1862-41-5. Pack Sizes: 1 mg. Product ID: HY-N7227. | |
| Brostallicin hydrochloride | Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Accordingly, brostallicin may be effective against MMR-defective tumors that are refractory to various anticancer agents. Synonyms: PNU-166196; PNU 166196; PNU166196; 4-(2-bromoacrylamido)-N-(5-(5-(5-(2-guanidinoethylcarbamoyl)-1-methyl- 1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H- pyrrol-3-yl)-1-methyl-1H-pyrrole-2-carboxamide. CAS No. 203258-38-2. Molecular formula: C30H36BrClN12O5. Mole weight: 760.05. | |
| Cafestol | Cafestol is a natural bioactive substance isolated from the unsaponifiable fraction of petroleum ether extract of coffee beans, it acts as a GST (glutathione S-transferase) inducer and exhibits chemoprotective activity. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Synonyms: cafestol; 469-83-0; cafesterol; CCRIS 1518; AC465T6Q6W; CHEBI:3291; (3bS,5aS,7R,8R,10aR,10bS)-7-(hydroxymethyl)-10b-methyl-3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-5a,8-methanocyclohepta[5,6]naphtho[2,1-b]furan-7-ol. Grades: ≥98%. CAS No. 469-83-0. Molecular formula: C20H28O3. Mole weight: 316.4. | |
| Canfosfamide | Canfosfamide hydrochloride is the hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation. S-transferase P1-1 is an enzyme that is overexpressed in many human malignancies. Synonyms: TELCYTA; TLK286; TLK 286; TLK-286. CAS No. 158382-37-7. Molecular formula: C26H40Cl4N5O10PS. Mole weight: 787.47. | |
| Canfosfamide Hydrochloride | Canfosfamide is a modified glutathione analogue as a small-molecule antineoplastic compound with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation. S-transferase P1-1 is an enzyme that is overexpressed in many human malignancies. Uses: Glutathione transferase inhibitor. Synonyms: Telcyta; TER 286; TLK 286; TER286; TLK286; TER-286; TLK-286; N5- ( ( (2- ( (bis (bis (2-chloroethyl) amino) phosphoryl) oxy) ethyl) sulfonyl) -D-alanyl) -N5- ( (R) -carboxy (phenyl) methyl) -L-glutamine hydrochloride. Grades: ≥98%. CAS No. 439943-59-6. Molecular formula: C26H41Cl5N5O10PS. Mole weight: 823.93. | |
| Curzerene | Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 ( GSTA1 ) mRNA and protein expression. Curzerene induces cell apoptosis [1]. Uses: Scientific research. Group: Natural products. CAS No. 17910-09-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1963. | |
| Ethacrynic acid | Ethacrynic acid has anti-inflammatory and anticancer activity. Ethacrynic acid is an orally active diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways. Ethacrynic acid is a radiosensitizer. Ethacrynic acid can inhibit airway smooth muscle (ASM) contraction in mice. Ethacrynic acid can increase the outflow of aqueous humor from the eye for the study of glaucoma [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Etacrynic acid. CAS No. 58-54-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1640. | |
| Ezatiostat | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Synonyms: Telintra; Gamma-Glu-S-BzCys-PhGly diethyl ester; TLK-199; TLK 199. CAS No. 168682-53-9. Molecular formula: C27H35N3O6S. Mole weight: 529.652. | |
| Ezatiostat hydroChloride | Ezatiostat hydrochloride is the hydrochloride salt form of Ezatiostat. Ezatiostat, also called as Telintra or TER 199, is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activi. Synonyms: ethyl (2S)-2-amino-5-[[(2R)-3-benzylsulfanyl-1-[[(1R)-2-ethoxy-2-oxo-1-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoate;hydrochloride ezatiotsat gamma-Glu-S-BzCys-PhGly diethyl ester gamma-glutamyl-S-(benzyl)cysteinyl-phenylglycine diethyl ester. CAS No. 286942-97-0. Molecular formula: C27H35N3O6S.HCl. Mole weight: 566.11. | |
| Galaxolide | Galaxolide can induce estrogenic activity ( Estrogen Receptor/ERR ), trigger oxidative stress and genotoxicity, and induce EROD and GST ( Glutathione S-transferase ) enzyme activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222-05-5. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W100026. | |
| glutathione transferase | A group of enzymes of broad specificity. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Also catalyses the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. Group: Enzymes. Synonyms: glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST. Enzyme Commission Number: EC 2.5.1.18. CAS No. 50812-37-8. Glutathione S-Transferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2754; glutathione transferase; EC 2.5.1.18; 50812-37-8; glutathione S-transferase; glutathione S-alkyltransferase; glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-aralkyltransferase; glutathione S-alkyl transferase; GST. Cat No: EXWM-2754. | |
| L-Glutathione, Reduced | L-Glutathione, Reduced. Synonyms: γ-L-Glutamyl-L-cysteinyl-glycine, GSH. CAS No. 70-18-8. Product ID: CDC10-0057. Molecular formula: C10H17N3O6S. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; L-Glutathione, Reduced; CDC10-0057; 70-18-8; C10H17N3O6Sl; γ-L-Glutamyl-L-cysteinyl-glycine, GSH; 200-725-4; MFCD00065939; 70-18-8. Purity: ≥98.0%. Color: White. EC Number: 200-725-4. Physical State: Powder. Solubility: H2O: 50 mg/mL. Quality Level: 300. Storage: 2-8°C. Application: L-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads. It has been used to prepare a standard curve for GSH analyses. Boiling Point: 754.5±60.0 °C(Predicted). Melting Point: 192-195 °C (dec.) (lit.). Density: 1.4482 g/mL(rough estimate). |  |
| Native E. coli PreScission Protease | PreScission Protease is a fusion protein of glutathione S-transferase (GST) and human rhinovirus (HRV) type 14 3C protease. The protease specifically recognizes a subset of sequences which include the core amino acid sequence Leu-Phe-Gln/Gly-Pro cleaving between the Gln and Gly residues. Substrate recognition and cleavage are likely to be dependent not only upon primary structural signals, but also upon the secondary and tertiary structures of the fusion protein as well. Applications: During cleavage reactions, it is recommended that samples be removed at various time points and analyzed by sds-page to estimate the yield, purity, and extent of digestion. the amount of prescission protease, temperature and length of incubation required for complete digestion of a given gst fusion partner may vary depending on the fusion partner. optimal conditions for each fusion should be determined in pilot experiments. digestion may be improved by adding triton x-100, tween 20, nonidet, or np40 to a concentration of 0.01%. concentrations of these detergents up to 1% do not inhibit prescission protease. Group: Enzymes. Synonyms: . Purity: >90% by SDS-PAGE. PSP. Activity: >10000 IU/mg. Appearance: Sterile colorless liquid. Storage: Should be stored in small aliquots at -20°C to -80°C for long term. Source: E. coli. PreScission Protease; PSP. Cat No: NATE-0877. | |
| PTACH | PTACH is a SAHA-based novel inhibitor of histone deacetylase (HDAC). It exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1.1 to 9.1 μM. It shows strong activity in cancer cell growth inhibition assay. It inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 μM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer. It could inhibit the cell growth of a variety of lymphoid malignant cells through apoptosis induction, more effectively than SAHA. It upregulated anti-oxidant molecules including peroxiredoxin 1 and 2 and glutathione S-transferase at the protein level. It exhibits cytotoxicity by sustaining ROS at the higher level greater than SAHA. Uses: Ptach exerts potent growth inhibition against various human cancer cells. it could inhibit the cell growth of a variety of lymphoid malignant cells through apoptosis induction. Synonyms: NCH-51; NCH 51; NCH51. PTACH;Cpd 51;S-(7-Oxo-7-((4-phenylthiazol-2-yl)amino)heptyl) 2-methylpropanethioate;S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate;2-Methylpropanethioicacid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl]ester. Grades: >98%. CAS No. 848354-66-5. Molecular formula: C20H26N2O2S2. Mole weight: 390.56. | |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Synonyms: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. | |
| S- (2-Hydroxyethyl) glutathione | A glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinylglycine; L-N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl) thio]ethyl]glutamine; N-[N-L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinyl]glycine; S-( β -Hydroxyethyl) glutathione. Grades: Highly Purified. CAS No. 28747-20-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| S- (2-Hydroxyethyl) glutathione-d4 Hydrochloride | A labeled glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl-d4)-L-cysteinylglycine Hydrochloride; N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl-d4) thio]ethyl]tamine Hydrochloride; S-( β-Hydroxyethyl-d4)glutathione Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| S-(2-Hydroxyethyl)glutathione-d4 Hydrochloride | A labelled glutathione derivative. It acts as an inhibitor of glutathione S-transferase. Synonyms: L-γ-Glutamyl-S-(2-hydroxyethyl-d4)-L-cysteinylglycine Hydrochloride; N-[1-[(Carboxymethyl)carbamoyl]-2-[(2-hydroxyethyl-d4)thio]ethyl]-L-glutamine Hydrochloride; S-(β-Hydroxyethyl-d4)glutathione Hydrochloride. Molecular formula: C12H18D4ClN3O7S. Mole weight: 391.86. | |
| S- (2-Hydroxyethyl) glutathione Hydrochloride | A glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinylglycine Hydrochloride; N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl) thio]ethyl]. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Senecionine | Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin. CAS No. 130-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2560. | |
| TA-3037A | TA-3037A is a glutathione S-transferase inhibitor isolated from the fermentation broth of Streptomyces sp. TA-3037. Synonyms: TA 3037A; (Z)-3,4-Dihydro-2-oxo-3-(phenylmethylene)-2H-1,4-benzoxazine-5-carboxylic acid. CAS No. 143651-44-9. Molecular formula: C16H11NO4. Mole weight: 281.26. | |
| tert-Butylhydroquinone | tBHQ is an antioxidant in induction of AP-1, NF-κB, and glutathione S-transferase gene expression. It also disrupts ability of Kelch-like ECH-associated protein 1(Keap1) to target Nrf2, a bZIP transcription factor, for proteasome-mediated degradation and promote nuclear accumulation of Nrf2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1948-33-0. Pack Sizes: 5g, 25g. Molecular Formula: C10H14O2. US Biological Life Sciences. | Worldwide |
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