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| Product | Description | |
|---|---|---|
| glycosphingolipid deacylase | Does not act on sphingolipids such as ceramide. Not identical with EC 3.5.1.23 ceramidase. Group: Enzymes. Synonyms: glycosphingolipid ceramide deacylase. Enzyme Commission Number: EC 3.5.1.69. CAS No. 122544-53-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4459; glycosphingolipid deacylase; EC 3.5.1.69; 122544-53-0; glycosphingolipid ceramide deacylase. Cat No: EXWM-4459. |  |
| TLC neutral glycosphingolipid mixture | TLC neutral glycosphingolipid mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine and porcine. TLC neutral glycosphingolipid mixture; TLC; Neutral Glycosphingolipid Mixture (TLC)(qualmixture); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-122. | |
| 1,2,3,4-Tetra-O-benzoyl-D-glucopyranose-13C6 | Used in the preparation of α-Glycosphingolipids, important in the innate-type immune response to Gram-negative bacteria. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrabenzoate-D-glucopyranose. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. |  Worldwide |
| 1,3,4,6-Tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-a-D-glucopyranosyl)-b-D-galactopyranoside | 1,3,4,6-Tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-a-D-glucopyranosyl)-b-D-galactopyranoside is a specialized carbohydrate compound primarily used in biomedical research. It's often applied in the synthesis of glycosphingolipid analogues, which possess potential therapeutic relevance against numerous diseases such as cancer and Gaucher's disease. Synonyms: 1,3,4,6-Tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-a-D-glucopyranosyl)-b-D-galactopyranoside; (2R,3R,4S,5S,6R)-2,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)-3-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxyoxane; Benzyl 3,4,6-tri-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-alpha-D-glucopyranosyl)-beta-D-galactopyranoside; Benzyl 2-O-(2,3,4,6-tetra-O-benzyl-alpha-D-glucopyranosyl)- 3,4,6-tri-O-benzyl-beta-D-galactopyranoside; DTXSID30747138; Benzyl 2-O-(2,3,4,6-tetra-O-benzyl-|A-D-glucopyranosyl)- 3,4,6-tri-O-benzyl-|A-D-galactopyranoside; Benzyl 2-O-(2,3,4,6-tetra-O-benzyl-a-D-glucopyranosyl)- 3,4,6-tri-O-benzyl-b-D-galactopyranoside. CAS No. 64694-20-8. Molecular formula: C68H70O11. Mole weight: 1063.28. |  |
| 18:1 Ether Coenzyme A Ammonium salt | 18:1 Ether Coenzyme A Ammonium salt, a crucial ingredient in synthesizing glycosphingolipids and phospholipids, holds an instrumental position in the oxidative disposal of fatty acids while also being a vital agent for drug and toxin metabolism. It is a medically potent recourse for lipid abnormalities and certain inherited metabolic disorders, offering a path of primacy for therapeutic intervention. Synonyms: (9Z-octadecenyl) Coenzyme A (ammonium salt); triazanium (2R, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -4-hydroxy-2- ( ( ( ( ( ( (R) -3-hydroxy-2, 2-dimethyl-4- ( (3- ( (2- ( ( (Z) -octadec-9-en-1-yl) thio) ethyl) amino) -3-oxopropyl) amino) -4-oxobutoxy) oxidophosphoryl) oxy) oxidophosphoryl) oxy) methyl) tetrahydrofuran-3-yl hydrogen phosphate; 9H-Purin-6-amine, 9-[(2ξ)-5-O-[hydroxy[[hydroxy[(3R)-3-hydroxy-2,2-dimethyl-4-[[3-[[2-[(9Z)-9-octadecen-1-ylthio]ethyl]amino]-3-oxopropyl]amino]-4-oxobutoxy]phosphinyl]oxy]phosphinyl]-3-O-phosphono-β-D-threo-pentofuranosyl]-, triammonium salt. Grades: >99%. CAS No. 2260670-62-8. Molecular formula: C39H79N10O16P3S. Mole weight: 1068.46. | |
| 2,3,4,6-Tetra-O-acetyl-D-mannopyranose | 2,3,4,6-Tetra-O-acetyl-D-mannopyranose is a bioactive carbohydrate used in biomedical research. It is primarily instrumental in developing antiviral and anticancer drugs by stabilizing glycoprotein structures. Additionally, it's used in studying Mannose-type Glycosphingolipids related diseases. Synonyms: Tetra-O-acetyl-d-mannopyranose; [(2R,3R,4S,5S)-3,4,5-triacetyloxy-6-hydroxyoxan-2-yl]methyl acetate. Grades: 95%. CAS No. 140147-37-1. Molecular formula: C14H20O10. Mole weight: 348.304. | |
| 2-(Dimethylamino)-6-dodecanoylnaphthalene | 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine is a fluorescent membrane probe used in phospholipid multilamellar aggregates which distinguishes between phase transitions, phase fluctuations and the coexistence of phase domains. Studies indicate that the bulky and highly hydrated polar head groups of glycosphingolipids interact well with 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine. The fluorescence is derived from the naphthalene moiety, in which a small dipole moment exists due to a partial charge separation between the 2-dimethylamino and the 6-carbonyl residues. This fluorescent tag is ideal to study dipolar relaxation because this compound emits different light depending on the environment it is in. For instance, 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine emits red light in a polar solvent and blue light in an apolar solvent. Group: Biochemicals. Alternative Names: 1-[6-(Dimethylamino)-2-naphthalenyl]-1-dodecanone; 6-Lauroyl-2- (dimethylamino) naphthalene; N,N-Dimethyl-6-dodecanoyl-2-naphthylamine; Laurdan. Grades: Highly Purified. CAS No. 74515-25-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C??H??NO, Molecular Weight: 353.54. US Biological Life Sciences. | Worldwide |
| [2-Methoxy-4-(2-nitrovinyl)phenyl] b-D-galactopyranoside | [2-Methoxy-4-(2-nitrovinyl)phenyl] b-D-galactopyranoside, a chemical compound utilized in biomedical research, plays a fundamental role in efficiently detecting the β-galactosidase activity present in cells. Additionally, its employment in further exploring the glycosphingolipid metabolism in relation to Alzheimer's disease has propelled its importance even further. Synonyms: MNP-Gal. CAS No. 70622-78-5. Molecular formula: C15H19NO9. Mole weight: 357.31. | |
| 5-Hydroxy-1-tetralone | 5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples [1]. Uses: Scientific research. Group: Natural products. CAS No. 28315-93-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-76981. |  |
| α-D-Cellobiose Heptaacetate Trichloroacetimidate | α-D-Cellobiose Heptaacetate Trichloroacetimidate is an intermediate used in the preparation of glycosphingolipid analogs and their binding with HIV-1 recombinant Gp120. Synonyms: 4-O-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-α-D-glucopyranose 2,3,6-triacetate 1-(2,2,2-trichloroethanimidate). CAS No. 130703-21-8. Molecular formula: C28H36Cl3NO18. Mole weight: 780.94. | |
| α-Synuclein (34-45) (human) | The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity. Synonyms: α-syn (34-45) (human); H-Lys-Glu-Gly-Val-Leu-Tyr-Val-Gly-Ser-Lys-Thr-Lys-OH; L-Lysine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-leucyl-L-tyrosyl-L-valylglycyl-L-seryl-L-lysyl-L-threonyl-. Grades: ≥95%. CAS No. 2170181-52-7. Molecular formula: C59H101N15O18. Mole weight: 1308.52. | |
| α-Synuclein (67-78) (human) | The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity. Synonyms: α-syn (67-78) (human); H-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-OH; L-Alanine, glycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-L-threonyl-L-alanyl-L-valyl-. Grades: ≥95%. CAS No. 2243206-99-5. Molecular formula: C43H76N12O15. Mole weight: 1001.14. | |
| Benzyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-a-D-glucopyranoside | Benzyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-2-deoxy-α-D-glucopyranoside is an esteemed compound, exerting profound influence as a resplendent mimic of glycosphingolipids in the realms of immunology and oncology. Molecular formula: C29H39NO15. Mole weight: 641.62. | |
| C16 Galactosyl(α) Ceramide (d18:1/16:0) | It is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid. Synonyms: D-galactosyl-α-1,1'-N-palmitoyl-D-erythro-sphingosine; Hexadecanamide, N-[(1S,2R,3E)-1-[(α-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-; α C16 Galactosylceramide (d18:1/16:0); C16 α-D-galactosyl ceramide; N-(hexadecanoyl)-1-α-galactosyl-sphing-4-enine; N-((2S,3R,E)-3-hydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)palmitamide; N-[(2S,3R,4E)-1-(α-D-Galactopyranosyloxy)-3-hydroxy-4-octadecen-2-yl]hexadecanamide; α-GalCer(d18:1/16:0). Grades: >99%. CAS No. 2260795-77-3. Molecular formula: C40H77NO8. Mole weight: 700.04. | |
| C2 Adamantanyl Glucosylceramide (d18:1/2:0) | C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid. It increases levels of glycosphingolipids in Vero cells at low concentrations (≤20 μM) but decreases them at high concentrations (≥40 μM). Pretreatment of microsomes with AdaGluCer increases production of adamantanyl lactosylceramide (AdaLacCer) and reduces synthesis of LacCer from exogenous GlcCer. AdaGluCer inhibits glucocerebrosidase activity in vitro in a pH-dependent manner. Synonyms: N-(1-Adamantaneacetyl) Glucosylceramide; Adamantanyl GluCer(d18:1/2:0); Adamantanyl Glucosylceramide (d18:1/2:0); AdaGluCer(d18:1/2:0). Grades: ≥98%. Molecular formula: C36H61NO8. Mole weight: 635.87. | |
| ceramidase | Ceramidase (EC 3.5.1.23, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P). Group: Enzymes. Synonyms: acylsphingosine deacylase; glycosphingolipid ceramide deacylase. Enzyme Commission Number: EC 3.5.1.23. CAS No. 37289-06-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4413; ceramidase; EC 3.5.1.23; 37289-06-8; acylsphingosine deacylase; glycosphingolipid ceramide deacylase. Cat No: EXWM-4413. | |
| Cerebrosides (Brain) | Cerebrosides are glycosphingolipids with either glucose or galactose as a polar head group. Cerebrosides are amphipathic in nature. They comprise the major component of the myelin lipids. Cerebrosides are part of non-neural cells including the epithelial cells associated with skin and the digestive system. Synonyms: Total Cerebrosides (Brain, Porcine). Grades: >99%. CAS No. 383906-25-0. Molecular formula: C48H93NO8. Mole weight: Average: 781.953. | |
| Digalactosylceramide | Digalactosylceramide is a cutting-edge compound, demonstrating prodigious potential for studying a plethora of intricate neurologic afflictions. As a paramount glycosphingolipid, it adeptly augments myelin synthesis within the central nervous system, promulgating neuronal rejuvenation. Synonyms: Galabiosylceramide; 1-O-(4-O-a-D-Galactopyranosyl-b-D-galactopyranosyl)?-ceramide. Grades: 98%. CAS No. 217635-91-1. Molecular formula: C46H87NO13. Mole weight: 862.18. | |
| Endoglycoceramidase II from Rhodococcus sp., Recombinant | In enzymology, an endoglycosylceramidase (EC 3.2.1.123) is an enzyme that catalyzes the chemical reaction: oligoglycosylglucosylceramide + H2O<-> ceramide + oligoglycosylglucose. Thus, the two substrates of this enzyme are oligoglycosylglucosylceramide and H2O, whereas its two products are ceramide and oligoglycosylglucose. This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O-and S-glycosyl compounds. Applications: Endoglycoceramidase ii from rhod oc occus sp. has been used in a study to assess the differentiation of glycosphingolipid-derived glycan structural isomers by liquid chromatography and mass spectrometry. endoglycoceramidase ii from rhodococcus sp. has also been used in a study to investigate structural and mechanistic analyses of endoglycoceramidase ii. Group: Enzymes. Synonyms: EC 3.2.1.123, endoglycoceramidase; EGCase; glycosyl-. Enzyme Commission Number: EC 3.2.1.123. CAS No. 105503-61-5. EGCase. Storage: -20°C. Form: Solution in 20 mM sodium acetate buffer, pH 6.0, containing 0.2% BSA and 0.1% Lubrol PX. Source: E. coli. Species: Rhodococcus sp. EC 3.2.1.123, endoglycoceramidase; EGCase; glycosyl-N-acetyl-sphingosine 1,1-β-D-glucanohydrolase, oligoglycosylglucosylceramide glycohydrolase; oligoglycosylglucosyl (1<->1)ceramide glycohydrolase. Cat No: NATE-0210. | |
| endoglycosylceramidase | An enzyme from Rhodococcus sp. that degrades various acidic and neutral glycosphingolipids to oligosaccharides and ceramides, by cleaving a glucosyl bond. Does not act on monoglycosylceramides. cf. EC 3.2.1.62 glycosylceramidase. Group: Enzymes. Synonyms: endoglycoceramidase; EGCase; glycosyl-N-acetyl-sphingosine 1,1-β-D-glucanohydrolase, oligoglycosylglucosylceramide glycohydrolase; oligoglycosylglucosyl(1<->1)ceramide glycohydrolase. Enzyme Commission Number: EC 3.2.1.123. CAS No. 105503-61-5. EGCase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3806; endoglycosylceramidase; EC 3.2.1.123; 105503-61-5; endoglycoceramidase; EGCase; glycosyl-N-acetyl-sphingosine 1,1-β-D-glucanohydrolase, oligoglycosylglucosylceramide glycohydrolase; oligoglycosylglucosyl(1<->1)ceramide glycohydrolase. Cat No: EXWM-3806. | |
| galactosylceramide sulfotransferase | Also acts on lactosylceramide. Group: Enzymes. Synonyms: GSase; 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase. Enzyme Commission Number: EC 2.8.2.11. CAS No. 9081-6-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3370; galactosylceramide sulfotransferase; EC 2.8.2.11; 9081-06-5; GSase; 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase. Cat No: EXWM-3370. | |
| Ganglioside GD1b (Porcine Brain) Triammonium salt | Ganglioside GD1b (Porcine Brain) Triammonium salt, a crucial glycosphingolipid, exerts vital influence over cell signaling and adhesion in the human body. Given its emerging therapeutic implications in treating neurological ailments like Parkinson's disease and multiple sclerosis, and certain cancers, it remains the focus of extensive studies. Meanwhile, its potential for modulating immune cell function in the realm of autoimmune disorders is compelling scientists to explore its promising attributes further. Synonyms: Ganglioside GD1b (porcine brain, triammonium salt). Grades: >99%. CAS No. 2315262-17-8. Molecular formula: C84H154N6O39. Mole weight: 1872.14. | |
| Gangliosides | Gangliosides is a glycosphingolipid predominantly located within the nervous system. These multifaceted compounds assume a pivotal role in facilitating intercellular exchange, governing neural growth and modulating synaptic adaptability. Synonyms: GM1, GD1a, GD1b, GT1b gangliosides, mixed ammoinum salts. | |
| GD3-Ganglioside | GD3-Ganglioside, a glycosphingolipid, is an intricate modulator of cell growth, differentiation and apoptosis. Anti-cancer therapies utilizing GD3-Ganglioside as a therapeutic target have shown significant promise, making it a distinguished focus of research in the realm of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. In addition to the fascinating roles delineated above, GD3-Ganglioside has been extensively studied for its potential as an antiviral agent owing to its involvement in the immune response. Synonyms: disialoganglioside GD3; 62010-37-1; Ganglioside GD3 Sodium Salt; Ganglioside GD3 disodium salt; PD077037. CAS No. 62010-37-1. Molecular formula: C70H123N3Na2O29. Mole weight: 1516.7. | |
| Globoside | Globoside is a glycosphingolipid abundantly present in human erythrocytes and diverse tissues, exhibiting multifaceted roles as a microbial toxin receptor and a regulator of cell adhesion and signal transduction. Synonyms: Globotetraosylceramide; Cytolipins; GlcNAc (b1-3)Gal (a1-4) Gal (b1-4) Glc b1-1 Cer. CAS No. 11034-93-8. Molecular formula: C56H102N2O23. Mole weight: 1171.41. | |
| globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase | Globoside is a neutral glycosphingolipid in human erythrocytes and has blood-group-P-antigen activity. The enzyme requires a divalent cation for activity, with Mn2+ required for maximal activity. UDP-GalNAc is the only sugar donor that is used efficiently by the enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity. Lactosylceramide, globoside and gangliosides GM3 and GD3 are not substrates. For explanation of the superscripted '3' in the systematic name, see GL-5.3.4. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgalactosamine: globotriaosylceramide β-3-N-acetylgalactosaminyltransferase; galactosylgalactosylglucosylceramide β-D-acetylgalactosaminyltransferase; UDP-N-acetylgalactosamine: globotriaosylceramide β1,3-N-acetylgalactosaminyltrans. Enzyme Commission Number: EC 2.4.1.79. CAS No. 62213-46-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2619; globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase; EC 2.4.1.79; 62213-46-1; uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgala | |
| glucosylceramide β-1,4-galactosyltransferase | Involved in the synthesis of several different major classes of glycosphingolipids. Group: Enzymes. Synonyms: lactosylceramide synthase; uridine diphosphate-galactose:glucosyl ceramide β 1-4 galactosyltransferase; UDP-Gal:glucosylceramide β1?4galactosyltransferase; GalT-2 (misleading); UDP-galactose:β-D-glucosyl-(1<->1)-ceramide β-1,4-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.274. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2506; glucosylceramide β-1,4-galactosyltransferase; EC 2.4.1.274; lactosylceramide synthase; uridine diphosphate-galactose:glucosyl ceramide β 1-4 galactosyltransferase; UDP-Gal:glucosylceramide β1?4galactosyltransferase; GalT-2 (misleading); UDP-galactose:β-D-glucosyl-(1<->1)-ceramide β-1,4-galactosyltransferase. Cat No: EXWM-2506. | |
| GM3-Ganglioside labelled by NBD ammonium | GM3-Ganglioside labelled by NBD ammonium is a vital tool in the biomedical industry used for researching and diagnosing various diseases. This product plays a crucial role in studying and understanding the targeting and metabolism of GM3-Ganglioside, a glycosphingolipid involved in neurological disorders and cancer progression. Its NBD ammonium label allows for fluorescence-based detection and visualization in biological systems, enabling accurate analysis and potential therapeutic advancements. Synonyms: N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole. Grades: 95%. Molecular formula: C55H90N6O24·H3N. Mole weight: 1236.36. | |
| GM4-Ganglioside | GM4-Ganglioside is an essential glycosphingolipid exhibiting tremendous potential as a research for neurodegenerative ailments including Alzheimer's disease and Parkinson's disease. Through its remarkable neuroprotective properties, GM4-Ganglioside safeguard neurons from degeneration. CAS No. 66456-69-7. Molecular formula: C57H106N2O17 xNa. Mole weight: 1091.45 (free acid basis). | |
| Lactosyl-b-1,1-N-octanoyl-L-threo-sphingosine | Lactosyl-b-1,1-N-octanoyl-L-threo-sphingosine is a synthetic glycosphingolipid (GSL) with nonnatural stereochemistry. It is a caveolar uptake inhibitor, which blocks SV40 virus infection. Synonyms: C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0); D-lactosyl-β1-1'-N-octanoyl-L-threo-sphingosine; C8-threo-LacCer. Grades: >99%. CAS No. 939036-94-9. Molecular formula: C38H71NO13. Mole weight: 749.97. | |
| Lactosylceramide | Lactosylceramide, a vital glycosphingolipid molecule, plays an essential role in cell signaling, cell migration, and apoptosis, and is intricately involved in regulating inflammation and immune responses. Synonyms: Ceramide b-lactoside; Ceramide dihexoside (CDH); b-D-Galactosyl-(1-4)-D-glucosylceramide; Lactosyl-N-acylsphingosine; LacCer. CAS No. 4682-48-8. | |
| Lactosyl Ceramide, Bovine | Lactosyl Ceramide neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of ERK 1 (p44 MAP kinase). Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells. Applications: An inducer of ras-gtp loading, mek and raf kinases, p44 map kinase, c-fos expression. Group: Coenzymes. Synonyms: Ceramide β-lactoside. CAS No. 4682-48-8. Purity: ≥98%. Mole weight: 960.4. Form: Solid. Ceramide β-lactoside; Lactosyl Ceramide, Bovine; 4682-48-8. Cat No: COEC-107. | |
| Methyl 2,3,6-tri-O-benzoyl-a-D-galactopyranoside | Methyl 2,3,6-tri-O-benzoyl-a-D-galactopyranoside is an extensively utilized carbohydrate chemical employed in the synthesis of glycosphingolipids, demonstrating paramount significance in profiling glycosylation of proteins amidst various disease studies like cancer and autoimmune disorders, which is why it has been reckoned as an apt identification and labeling agent for conducting these clinical assessments. Synonyms: α-D-Galactopyranoside, methyl, 2,3,6-tribenzoate; Methyl D-galactopyranoside 2,3,6-tribenzoate; NSC 50742; (2S,3R,4S,5S,6R)-6-((benzoyloxy)methyl)-5-hydroxy-2-methoxytetrahydro-2H-pyran-3,4-diyl dibenzoate; Methyl 2-O,3-O,6-O-tribenzoyl-alpha-D-galactopyranoside. Grades: ≥98%. CAS No. 3601-36-3. Molecular formula: C28H26O9. Mole weight: 506.50. | |
| Methyl 2-acetamido-4-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-6-O-(a-L-fucopyranosyl)-b-D-glucopyranoside | Methyl 2-acetamido-4-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-6-O-(a-L-fucopyranosyl)-b-D-glucopyranoside is a medicinal entity functioning as a veritable semblance of glycosphingolipids. Uniquely, this compound possesses prospective applications in studying immune dysregulation and inflammatory afflictions. Synonyms: GlcNAc-b,1-4-[Fuc-a,1-6]GlcNAc-b-O-Me. CAS No. 97242-84-7. Molecular formula: C23H40N2O15. Mole weight: 584.57. | |
| Miglustat | Miglustat is an inhibitor of the ceramide-specific glycosyltransferase, which catalyzes the first step of glycosphingolipid biosynthesis and is currently approved for the oral treatment of type I Gaucher disease (GD1). Uses: Enzyme inhibitors. Synonyms: Zavesca; Miglustat; NB-DNJ. Grades: >98%. CAS No. 72599-27-0. Molecular formula: C10H21NO4. Mole weight: 219.28. | |
| Myriocin | Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin is a useful biochemical research tool for depleting cells of sphingolipids. Group: Biochemicals. Alternative Names: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; (+)-Myriocin; ISP-I; NSC 177379; Thermozymocidin; (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid. Grades: Highly Purified. CAS No. 35891-70-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-(2,4-Dinitrophenyl-deoxygalactonojirimycin | N-(2,4-Dinitrophenyl-deoxygalactonojirimycin is a remarkable pharmaceutical compound utilized for the research of lysosomal storage disorders, encompassing a spectrum of debilitating ailments such as Gaucher's, Fabry's and Pompe's disease. Its pivotal role as a potent glucosidase inhibitor facilitates the research of glycosphingolipid build-up. Synonyms: 1,5-dideoxy-N-(2,4-dinitrophenyl)-1,5-imino-D-galactitol; N-(2,4-dinitrophenyl DGJ. | |
| N-(4,4-Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-dodecanoyl)sphingosyl 1-b-D-galactopyranoside | N-(4,4-Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-dodecanoyl)sphingosyl 1-b-D-galactopyranoside is an experimental compound, enabling the exploration of intricate phenomena regarding cell membrane dynamics and lipid trafficking. As an illuminating fluorogenic compound, it possesses the remarkable ability to precisely mark sphingolipids and glycosphingolipids. Molecular formula: C47H78BF2N3O8. Mole weight: 861.95. | |
| N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin | N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin is a potent inhibitor used in the biomedical industry for studying diseases associated with glycosphingolipid metabolism. It specifically targets the activity of glucosylceramide synthase, inhibiting the production of glucosylceramide, which plays a vital role in conditions like Gaucher disease and Fabry disease. Synonyms: N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin; 383417-50-3; (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-[6-(2,2,2-TRIFLUOROETHOXY)HEXYL]PIPERIDINE-3,4,5-TRIOL; (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[6-(2,2,2-trifluoroethoxy)hexyl]-3,4,5-piperidinetriol; DTXSID201123508; W-202585. CAS No. 383417-50-3. Molecular formula: C13H24F3NO5. Mole weight: 331.33. | |
| (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase | This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively. Asialo-GM3 and lactosylceramide are also substrates, but glycoproteins and oligosaccharides are not substrates. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-α-neuraminyl)-(2?3)-O-β-D-galactopyranosyl-(1?4)-β-D-glucopyranosyl]-ceramide 1,4-β-N-acetyl-D-galactosaminyltransferase acetylgalactosa. Enzyme Commission Number: EC 2.4.1.92. CAS No. 67338-98-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2632; (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase; EC 2.4.1.92; 67338-98-1; uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-gal | |
| Native Pseudomonas sp. Sphingolipid ceramide N-deacylase | Sphingolipid ceramide N-deacylase (SCDase) is derived from Pseudomonas and hydrolyzes the N-acyl linkage between fatty acids and sphingosine bases in ceramides of various sphingolipids. The enzyme also catalyzes the reverse reaction and possesses transacylation activity. SCDase acts on various acidic and neutral glycosphingolipids and sphingomyelin; however, it exhibits low activity with ceramides. Applications: Hydrolysis of n-acyl linkages between fatty acids and sphingosine bases sphingolipid hydrolysis. Group: Enzymes. Synonyms: SCDase; Sphingolipid ceramide N-deacylase. SCDase. Storage: Store at -20°C until use. Store reconstituted solution in aliquots at -20°C. Avoid freeze-thaw. Form: Solution in 50 mM sodium acetate (pH 6.0) containing 0.1% Lubrol PX. Source: Pseudomonas sp. Species: Pseudomonas sp. SCDase; Sphingolipid ceramide N-deacylase. Cat No: NATE-0896. | |
| N-Dodecyldeoxynojirimycin | N-Dodecyldeoxynojirimycin, a highly potent inhibitor widely employed in the biomedical field, manifests immense potential for treating a multitude of diseases. Its mechanistic action involves targeting precise enzymes intricately linked to the intricate glycosphingolipid metabolism. Synonyms: 1,5-Dideoxy-N-dodecyl-1,5-imino-D-glucitol. CAS No. 79206-22-7. Molecular formula: C18H37NO4. Mole weight: 331.49. | |
| neolactotetraosylceramide α-2,3-sialyltransferase | This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. This enzyme participates in glycosphingolipid biosynthesis-neo-lactoseries and glycan structures-biosynthesis 2. Group: Enzymes. Synonyms: sialyltransferase; cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase; sialyltransferase 3; SAT-3; CMP-N-acetylneuraminate: neolactotetraosylceramide α-2,3-sialyltransferase; CMP-N-acetylneuraminate:β-D-galactosyl-(1?4)-N-acetyl-β-D-glucosaminyl-(1?3)-β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide α-(2?3)-sialyltransfer. Enzyme Commission Number: EC 2.4.99.10. CAS No. 83745-06-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2694; neolactotetraosylceramide α-2,3-sialyltransferase; EC 2.4.99.10; 83745-06-6; sialyltransferase; cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase; sialyltransferase 3; SAT-3; CMP-N-acetylneuraminate: neolactotetraosylceramide α-2,3-sialyltransferase; CMP-N-acetylneuraminate:β-D-galactosyl-(1?4)-N-acetyl-β-D-glucosaminyl-(1?3)-β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide α-(2?3)-sialyltransferase. Cat No: EXWM-2694. | |
| PDMP hydrochloride | PDMP is an inhibitor of glucosyl ceramide synthase that inhibits the synthesis and shedding of gangliosides. It reduces lysosomal activity, enhances lysosomal permeability and cytotoxicity in cells. PDMP has been used as a tool for studying various effects of endogenous glycosphingolipids. Synonyms: DL-threo-PDMP hydrochloride; DL-erythro/threo-PDMP hydrochloride; 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; (+/-)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride. Grades: ≥98%. CAS No. 73257-80-4. Molecular formula: C23H38N2O3·HCl. Mole weight: 427. | |
| Sphingolipid TLC mixture-51 | Sphingolipid TLC mixture-51. Group: Others. Appearance: Liquid. Sphingolipid TLC mixture-51; TLC; Glycosphingolipid TLC Mixtures; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-069. | |
| Sphingolipid TLC mixture-53 | Sphingolipid TLC mixture-53. Group: Others. Appearance: Liquid. Sphingolipid TLC mixture-53; TLC; Glycosphingolipid TLC Mixtures; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-070. | |
| Sphingolipid TLC mixture-54 | Sphingolipid TLC mixture-54. Group: Others. Appearance: Liquid. Sphingolipid TLC mixture-54; TLC; Glycosphingolipid TLC Mixtures; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-071. | |
| Sphingolipid TLC mixture-55 | Sphingolipid TLC mixture-55. Group: Others. Appearance: Liquid. Sphingolipid TLC mixture-55; TLC; Glycosphingolipid TLC Mixtures; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-072. | |
| Sphingolipid TLC mixture-56 | Sphingolipid TLC mixture-56. Group: Others. Appearance: Liquid. Sphingolipid TLC mixture-56; TLC; Glycosphingolipid TLC Mixtures; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-073. | |
| UDP-a-D-galactose | UDP-a-D-galactose is a pivotal nucleotide sugar molecule crucial for biosynthesizing carbohydrates and galactose-containing polysaccharides. Its active involvement in the biosynthesis of glycosphingolipids, the building blocks of cell membranes, makes it indispensable. Any impairment of this molecule might trigger galactosemia and other ailments, accentuating its contribution to cellular homeostasis. Synonyms: UDP-galactose; uridine diphosphate galactose; UDP-D-galactopyranose; Uridine pyrophosphogalactose; UDP-alpha-D-Galactose; Uridinediphosphogalactose; UDP-Gal; Uridine 5'-diphosphate galactose; Uridine 5'-(alpha-D-galactopyranosyl pyrophosphate); Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-galactopyranosyl ester; Uridine 5'-(trihydrogen pyrophosphate), mono-alpha-D-galactopyranosyl ester. Grades: ≥95%. CAS No. 2956-16-3. Molecular formula: C15H24N2O17P2. Mole weight: 566.30. | |
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