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Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others [1]. Uses: Scientific research. Group: Peptides. CAS No. 8001-27-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2813.
Hirudin
Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 8001-27-2. Molecular formula: C287H440N80O110S6. Mole weight: 7027. Product ID: ACM8001272. Alfa Chemistry ISO 9001:2015 Certified.
Hirudin (54-65)
Hirudin (54-65) is a naturally occurring peptide in the salivary glands of blood-sucking leeches that has a blood anticoagulant property. Uses: Hirudin (54-65) is a peptide extracted from leeches, a natural anticoagulant found in the saliva of the medicinal leech. this specific sequence refers to amino acids 54 to 65 in the larger hirudin molecule.one of the main uses of hirudin (54-65) is its potent anticoagulant activity. by inhibiting thrombin, an essential enzyme in the blood coagulation cascade, hirudin (54-65) can prevent blood. Synonyms: L-Glutamine, glycyl-L-α-aspartyl-L-phenylalanyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-tyrosyl-L-leucyl-; L-Glutamine, N2-[N-[N-[N-[N-[1-[N-[N-[N-[N-(N-glycyl-L-α-aspartyl)-L-phenylalanyl]-L-α-glutamyl]-L-α-glutamyl]-L-isoleucyl]-L-prolyl]-L-α-glutamyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-; Glycyl-L-α-aspartyl-L-phenylalanyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-. Grade: 95%. CAS No. 113274-56-9. Molecular formula: C66H93N13O25. Mole weight: 1468.52.
Acetyl-Hirudin (54-65) (sulfated). Synonyms: Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH; acetyl-[tyr(so3h)63]-hirudin fragment 54-65. Grade: 95%. CAS No. 125441-00-1. Molecular formula: C68H95N13O29S. Mole weight: 1590.62.
Acetyl-hirudin(55-65)(sulfated)
Acetyl-hirudin(55-65)(sulfated). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACETYL-[TYR(SO3H)63]-HIRUDIN FRAGMENT 55-65;AC-HIRUDIN (55-65) (SULFATED);ACETYL-HIRUDIN (55-65) (SULFATED);AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN;AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR (SO3H)-LEU-GLN-OH;N-acetyl-(tyr(so3H)63)-hirudin *frag. Product Category: Heterocyclic Organic Compound. CAS No. 125441-01-2. Molecular formula: C66H92N12O28S. Mole weight: 1533.57. Product ID: ACM125441012. Alfa Chemistry ISO 9001:2015 Certified.
Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). It is a synthetic congener of the naturally occurring drug hirudin. It is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. It is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. It has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. It does not require a binding cofactor such as antithrombin and does not activate platelets. Synonyms: Hirulog; Hirulog I; Angiomax; Hirulog-1; Hirulog1; Hirulog 1; BG8967; BG 8967; BG-8967; LS-172701; LS172701; LS 172701. Grade: > 95%. CAS No. 128270-60-0. Molecular formula: C98H138N24O33. Mole weight: 2180.32.
Hirullin
Hirullin is originally isolated from the leech Hirudinaria manillensis. It is a hirudin-based fibrinogen recognition peptide inhibitor, which binds efficiently to thrombin (IC50= 4.2 μM, in bovine). Synonyms: H-SER-ASP-PHE-GLU-GLU-PHE-SER-LEU-ASP-ASP-ILE-GLU-GLN-OH. Grade: 95%. CAS No. 131147-81-4. Molecular formula: C68H96N14O29. Mole weight: 1573.57.
Lepirudin
Lepirudin is an anticoagulant that acts as a direct thrombin inhibitor. Lepirudin binds to both free and clot-bound thrombin. Lepirudin is approved for the treatment of heparin-induced thrombocytopenia (HIT). Uses: The treatment of heparin-induced thrombocytopenia (hit). Synonyms: (Leu1,Thr2)-Hirudin (desulfated); Lepirudin; Refludan; Refludin; Hbw 023; Hbw-023; Hbw023. CAS No. 138068-37-8. Molecular formula: C287H440N80O111S6. Mole weight: 6979.41.
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 μM. Synonyms: Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated). Grade: 95%. CAS No. 131791-98-5. Molecular formula: C64H86N10O25S. Mole weight: 1427.48.
venombin AB
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin. Group: Enzymes. Synonyms: gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Enzyme Commission Number: EC 3.4.21.55. CAS No. 104003-74-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4147; venombin AB; EC 3.4.21.55; 104003-74-9; gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Cat No: EXWM-4147.
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