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1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (HCl); an antiplatelet agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1100905-45-0. Pack Sizes: 100mg, 1g. Molecular Formula: C11H11FO2. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391194-36-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C33H33FN2O5, Molecular Weight: 556.62. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences.
2-Hydroxy-2-(4-fluorophenyl)ethylamine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-1-(4-FLUORO-PHENYL)-ETHANOL HYDROCHLORIDE;2-HYDROXY-2-(4-FLUOROPHENYL)ETHYLAMINE HYDROCHLORIDE;alpha-aminomethyl-p-fluoro-benzylalcohohydrochloride;alpha-aminomethyl-p-fluorobenzylalcoholhydrochloride;2-azanyl-1-(4-fluorophenyl)ethanol hydrochlor. Product Category: Heterocyclic Organic Compound. CAS No. 403-28-1. Molecular formula: C8H10FNO.HCl. Mole weight: 191.63. Purity: 0.96. IUPACName: 2-amino-1-(4-fluorophenyl)ethanol hydrochloride. Canonical SMILES: C1=CC(=CC=C1C(CN)O)F.Cl. Product ID: ACM403281. Alfa Chemistry ISO 9001:2015 Certified.
(2R)-3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid is the R-isomer of 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid (F595620); an impurity of Bicalutamide (B382000) which is a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal). Group: Biochemicals. Grades: Highly Purified. CAS No. 890658-79-4. Pack Sizes: 100mg, 1g. Molecular Formula: C10H11FO5S, Molecular Weight: 262.25. US Biological Life Sciences.
(2S)-3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid is the S-isomer of 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid (F595620); an impurity of Bicalutamide (B382000) which is a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C10H11FO5S, Molecular Weight: 262.25. US Biological Life Sciences.
(2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl) (hydroxy)methyl)-4-methylphenyl)-6-(hydroxymethyl) tetrahydro-2H-pyran-3,4,5-triol is an impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: Tetrahydro-2H-pyran-3,4,5-triol, (2S,3R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-4-methylphenyl)-6-(hydroxymethyl); Canagliflozin impurity 08. CAS No. 1951467-29-0. Molecular formula: C24H25FO6S. Mole weight: 460.52.
3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid is an impurity of Bicalutamide (B382000); a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal). Group: Biochemicals. Grades: Highly Purified. CAS No. 151262-57-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C10H11FO5S, Molecular Weight: 262.25. US Biological Life Sciences.
3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid-d4 is the isotope labelled analog of 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid (F595620); an impurity of Bicalutamide (B382000) which is a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H7D4FO5S, Molecular Weight: 266.279999999999. US Biological Life Sciences.
3-((4-Fluorophenyl)thio)-2-hydroxy-2-methylpropanoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(4-FLUOROPHENYLTHIO)-2-HYDROXY-2-METHYLPROPANOIC ACID;3-(4-Fluobenzenesulfhydryl)-2-;3-(4-Fluorobenzensulfydryl)-2-hydroxyl-2-methylpropionic acid(ForBicalutamide). Product Category: Heterocyclic Organic Compound. CAS No. 339530-91-5. Molecular formula: C10H11FO3S. Mole weight: 230.25. Product ID: ACM339530915. Alfa Chemistry ISO 9001:2015 Certified.
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185883-04-2. Pack Sizes: 5mg. Molecular Formula: C33H30F2N2O5, Molecular Weight: 572.6. US Biological Life Sciences.
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(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: Pitavastatin-3-Oxo Sodium Salt. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H21FNNaO4, Molecular Weight: 441.43. US Biological Life Sciences.
Worldwide
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt is one of pitavastatin derivatives. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: sodium (S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-3-oxohept-6-enoate; sodium (E,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-5-hydroxy-3-oxo-hept-6-enoate. Molecular formula: C25H21FNNaO4. Mole weight: 441.43.
Used as an antiandrogen, antineoplastic (hormonal). Group: Biochemicals. Alternative Names: ICI-176334-d4; Casodex-d4; N-[4-Cyano-3-trifluoromethyl) phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl Hydroxy Cerivastatin, Sodium Salt (M-24 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-5-hydroxymethyl-2-isopropylpyrid-3-yl}-3,5dihydroxyhept-6-enoate)
A metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: M-24 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-5-hydroxymethyl-2-isopropylpyrid-3-yl}-3,5dihydroxyhept-6-enoate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
(-)-Nebivolol intermediate. Group: Biochemicals. Alternative Names: (2E)-3-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-1-(5-fluoro-2-hydroxyphenyl)-2-propen-1-one. Grades: Highly Purified. CAS No. 797054-17-2. Pack Sizes: 500mg. US Biological Life Sciences.
(+)-Nebivolol intermediate. Group: Biochemicals. Alternative Names: (2E)-3-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-1-(5-fluoro-2-hydroxyphenyl)-2-propen-1-one. Grades: Highly Purified. CAS No. 797054-16-1. Pack Sizes: 500mg. US Biological Life Sciences.
Antidyskinetic; antipsychotic. Group: Biochemicals. Alternative Names: 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone; R-1625; Aloperidin; Bioperidolo; Brotopon; Dozic; Einalon S. Grades: Highly Purified. CAS No. 52-86-8. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Hydroxy Cerivastatin, Sodium Salt (M-23 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-2-isopropyl-5-methoxymethylpyrid-3-yl}-3,5-dihydroxyhept-6-enoate)
A metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: M-23 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-2-isopropyl-5-methoxymethylpyrid-3-yl}-3,5-dihydroxyhept-6-enoate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Rosuvastatin intermediate. Group: Biochemicals. Alternative Names: N-[4-(4-Fluorophenyl)-5-[(1E)-3-hydroxy-1-propen-1-yl]-6-isopropyl-2-pyrimidinyl]-N-methyl-methanesulfonamide. Grades: Highly Purified. CAS No. 910867-08-2. Pack Sizes: 100mg. US Biological Life Sciences.
An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 1-Propanesulfonamide, N-[4-(4-fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-2-hydroxy-N,2-dimethyl-; Rosuvastatin Impurity 37. Grades: >95%. CAS No. 2101546-09-0. Molecular formula: C19H24FN3O4S. Mole weight: 409.48.
It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-[4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]phenyl]-; Cabozantinib Impurity 06. CAS No. 1628530-42-6. Molecular formula: C27H22FN3O5. Mole weight: 487.48.
It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-(4-((6-hydroxy-7-methoxy-4-quinolinyl)oxy)phenyl)-; Dimethyl cabozantinib; Cabozantinib Impurity 05. Grades: 99% by HPLC. CAS No. 1628530-47-1. Molecular formula: C27H22FN3O5. Mole weight: 487.48.
One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: 2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-; Dacomitinib Impurity WYQJ. Grades: ≥95%. CAS No. 2190490-31-2. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81.
1-Hydroxymidazolam
1-Hydroxymidazolam. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RO 21-6347;ALPHA-HYDROXYMIDAZOLAM;8-CHLORO-6-(2-FLUOROPHENYL)-1-HYDROXYMETHYL-4H-IMIDAZO[1,5A][1,4]BENZODIAZEPINE;A-HYDROXYMIDAZOLAM;1-HYDROXY MIDAZOLAM;1-HYDROXYMIDAZOLAM;1Hydroxymidazolame;alpha-Hydroxymidazolame. Product Category: Heterocyclic Organic Compound. CAS No. 59468-90-5. Molecular formula: C18H13ClFN3O. Mole weight: 341.77. Product ID: ACM59468905. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1'-hydroxymidazolam.
An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: 2-(1-Amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-. Grades: Highly Purified. CAS No. 518048-03-8. Pack Sizes: 10mg. US Biological Life Sciences.
An labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: 2-(1-Amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-(methyl-d3)-6-oxo-4-pyrimidinecarboxamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(2E)-2,3-Dehydroxy Atorvastatin
(2E)-2,3-Dehydroxy Atorvastatin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic acid, Atorvastatin Eliminate. CAS No. 1105067-93-3. IUPAC Name: (E,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-5-hydroxyhept-2-enoic acid. Molecular Formula: C33H33FN2O4. Mole Weight: 540.62. Catalog: APS1105067933. SMILES: CC (C)c1c (C (=O)Nc2ccccc2)c (c3ccccc3)c (c4ccc (F)cc4)n1CC[C@@H] (O)C\C=C\C (=O)O. Format: Neat.
2-Fluoro-4-Desfluoro Bicalutamide
Synonyms: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(2-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; Bicalutamide EP Impurity B. Grades: > 95%. CAS No. 1159977-36-2. Molecular formula: C18H14F4N2O4S. Mole weight: 430.38.
2-Fluoro-α - [ (trimethylsilyl) oxy] benzeneacetonitrile is an intermediate in synthesizing 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone (C989465), a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 82128-76-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C11H14FNOSi. US Biological Life Sciences.
2-Hydroxy atorvastatin lactone. Group: Biochemicals. Alternative Names: 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide. Grades: Highly Purified. CAS No. 163217-74-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C33H33FN2O5. US Biological Life Sciences.
Worldwide
3-Fluoro-4-desfluoro Bicalutamide
3-Fluoro-4-desfluoro Bicalutamide. Group: Biochemicals. Alternative Names: N-[4-Cyano-3-trifluoromethyl) phenyl]-3-[ (3-fluorophenyl) sulfonyl]-2-hydroxy-2-methylpropanamide. Grades: Highly Purified. CAS No. 1166228-30-3. Pack Sizes: 2.5mg. Molecular Formula: C18H14F4N2O4S, Molecular Weight: 430.37. US Biological Life Sciences.
Worldwide
3-Oxo Atorvastatin tert-Butyl Ester
3-Oxo Atorvastatin tert-Butyl Ester is a Boc-protected oxo-derivative of Atorvastatin. Synonyms: (δR)-2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-β-oxo-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester; (R)-2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-β-oxo-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-hepta. Grades: > 95%. CAS No. 134394-98-2. Molecular formula: C37H41FN2O5. Mole weight: 612.75.
3-Oxo Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 3-Oxo Rosuvastatin SodiuM Salt;-7-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-5-pyriMidinyl]-5-hydroxy-3-oxo-. Grades: > 95%. CAS No. 1346606-28-7. Molecular formula: C22H25FN3O6S. Na. Mole weight: 501.51.
(3R,5R)-Rosuvastatin lactone
(3R,5R)-Rosuvastatin lactone. Group: Biochemicals. Alternative Names: N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide; Rosuvastatin-5R-lactone. Grades: Highly Purified. CAS No. 503610-43-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C22H26FN3O5S. US Biological Life Sciences.
Worldwide
(3R)-Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity
An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity; (3R)-4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Cyclic 6-Hydroxy Impurity. Grades: 90%. Molecular formula: C33H34FN2NaO7. Mole weight: 612.62.
(3'S,3R,4S)-Desfluoro Ezetimibe
An stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-2-azetidinone. Grades: > 95%. CAS No. 190595-66-5. Molecular formula: C24H22FNO3. Mole weight: 391.45.
(3S,3R,4S)-Desfluoro Ezetimibe
(3S,3R,4S)-Desfluoro Ezetimibe. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-2-azetidinone; [3R-[3α(S*),4 β]]-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-hydroxy-3-phenylpropyl)-2-azetidinone. Grades: Highly Purified. CAS No. 190595-66-5. Pack Sizes: 10mg. Molecular Formula: C24H22FNO3, Molecular Weight: 391.43. US Biological Life Sciences.
A metabolite of Paroxetine. Group: Biochemicals. Alternative Names: 5-[[(3S,4R)-4-(4-Fluorophenyl)-3-piperidinyl]methoxy]-2-methoxy-phenol; BRL 36583A; (-)-trans 4-(4-Fluorophenyl)-3-(3-hydroxy-4-methoxyphenoxymethyl) piperidine. Grades: Highly Purified. CAS No. 112058-89-6. Pack Sizes: 1mg, 2mg. US Biological Life Sciences.
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