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Idarubicin Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Synonyms: IMI30; IMI-30; IMI 30; NSC256439; NSC-256439; NSC 256439; 4-DMDR; IDA; 4-Demethoxydaunomycin; (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 4-Demethoxydaunorubicin; Idarubicine; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-92-9. Molecular formula: C26H27NO9. Mole weight: 497.50. BOC Sciences 2
Idarubicin United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Idarubicin-13C, d3 Idarubicin-13C, d3 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C25H24NO9[13C]D3. Mole weight: 501.51. BOC Sciences 8
Idarubicin-d3. Readily exchangeable deuterium labels in protic solvents Labelled Idarubicin, an orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug, 1mg. Molecular Formula: C26H24D3NO9. US Biological Life Sciences. USBiological 5
Worldwide
Idarubicin-d4 Idarubicin-d4 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C26H23NO9D4. Mole weight: 501.53. BOC Sciences 8
Idarubicin Dioxolane Hydrochloride Idarubicin Dioxolane Hydrochloride is a possible impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: (7S,9S)-7-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-9-(2-methyl-1,3-dioxolan-2-yl)-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride. Molecular formula: C28H31NO10.HCl. Mole weight: 578.01. BOC Sciences 8
Idarubicin hydrochloride 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-10mg. Molecular Weight 497.49. See USA prepack pricing. Molekula Americas
Idarubicin hydrochloride 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-25mg. Molecular Weight 497.49. See USA prepack pricing. Molekula Americas
Idarubicin hydrochloride Idarubicin hydrochloride is an anthracycline antileukemic agent. It inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin hydrochloride inhibits the growth of bacteria and yeasts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin hydrochloride. CAS No. 57852-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381. MedChemExpress MCE
Idarubicin hydrochloride solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Idarubicin Hydrochloride Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Uses: Antibiotics, antineoplastic. Synonyms: (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione Hydrochloride; 4-DMD HCl; 4-Demethoxydaunorubicin Hydrochloride; Idamycin; NSC 256439; Zavedos; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: >98%. CAS No. 57852-57-0. Molecular formula: C26H28ClNO9. Mole weight: 533.95. BOC Sciences 8
Idarubicin Hydrochloride Orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Alternative Names: (7S,9S)-Hydrochloride; Idamycin; NSC 256439; Zavedos. Grades: Highly Purified. CAS No. 57852-57-0. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
Idarubicin Impurity 2 Idarubicin Impurity 2 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Molecular formula: C28H31NO10. Mole weight: 541.55. BOC Sciences 8
Idarubicin Impurity 4 Idarubicin Impurity 4 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,12-dihydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,9-dihydroxy-7-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (7S-cis)-. CAS No. 85440-44-4. Molecular formula: C28H26F3NO9. Mole weight: 577.51. BOC Sciences 8
Idarubicin Isomer Idarubicin Isomer is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-; 4-Demethoxydaunorubicin, beta; 4-Demethoxy-7,9-di-epi-daunorubicin, beta; 7-O-β-Daunosaminyl-4-demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-93-0. Molecular formula: C26H27NO9. Mole weight: 497.49. BOC Sciences 8
Idarubicin Isomer hydrochloride Idarubicin Isomer hydrochloride is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (7S,9S)-9-Acetyl-7-(((2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Idarubicin Impurity 6; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside hydrochloride; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-, hydrochloride (1:1); 7-O-β-Daunosaminyl-4-demethoxydaunomycinone hydrochloride; Daunomycinone, 7-O-β-daunosaminyl-4-demethoxy-, hydrochloride. CAS No. 60660-72-2. Molecular formula: C26H27NO9.HCl. Mole weight: 533.96. BOC Sciences 8
Idarubicinol Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grade: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52. BOC Sciences 8
Idarubicinol-13C, d3 Idarubicinol-13C, d3 is a labelled nalogue of Idarubicinol. Grade: > 95%. Molecular formula: C26H26NO9D3. Mole weight: 503.53. BOC Sciences 8
Idarubicinol-d4 Idarubicinol-d4 is a labelled Idarubicinol. Synonyms: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grade: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55. BOC Sciences 8
Idarubicinol (Mixture of Diastereomers) Idarubicinol (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (7S,9S)-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-Naphthacenedione; [7S-[7α, 9α, 9(R*)]]-7-[(3-amino-2, 3, 6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7, 8, 9, 10-tetrahydro-6, 9, 11-trihydroxy-9-(1-hydroxyethyl)-5, 12-Naphthacenedione; 13-Dihydroidarubicin; 4-Demethoxydaunorubicino l; Antibiotic FCE 22723. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H29NO9, Molecular Weight: 499.51. US Biological Life Sciences. USBiological 3
Worldwide
Idarubicinone Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grade: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. BOC Sciences 8
Dianhydro Idarubicinaglycone Dianhydro Idarubicinaglycone is a key intermediate for the improved synthesis of 4-demethoxydaunomycinone and daunomycinone, which are metabolites of Daunorubicin. Daunorubicin is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,11-dihydroxy-5,12-tetracenedione; Bisanhydrous Idarubicin Aglycone; Idarubicin Impurity 1; 5,12-Naphthacenedione, 8-acetyl-6,11-dihydroxy-. Grade: ≥95%. CAS No. 84499-12-7. Molecular formula: C20H12O5. Mole weight: 332.31. BOC Sciences 7
4-Demethoxy-11-deoxydaunorubicin 4-Demethoxy-11-deoxydaunorubicin is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9-dihydroxy-5,12-naphthacenedione; 4-Demethoxy-11-deoxydaunomycin; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9-dihydroxy-, (7S,9S)-; (1S,3S)-3-Acetyl-3,12-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Dehydroxy Idarubicin. CAS No. 77312-66-4. Molecular formula: C26H27NO8. Mole weight: 481.49. BOC Sciences 4
4-Demethoxy-11-deoxydaunorubicin hydrochloride 4-Demethoxy-11-deoxydaunorubicin hydrochloride is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (7S,9S)-9-Acetyl-7-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9-dihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Dehydroxy Idarubicin hydrochloride; Idarubicin Impurity 5; (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9-dihydroxy-5,12-naphthacenedione hydrochloride; 4-Demethoxy-11-deoxydaunomycin hydrochloride; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9-dihydroxy-, (7S,9S)-, hydrochloride (1:1); (1S,3S)-3-Acetyl-3,12-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride. Grade: ≥95%. CAS No. 85440-46-6. Molecular formula: C26H27NO8.HCl. Mole weight: 517.96. BOC Sciences 4
8-Acetyl-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione 8-Acetyl-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione is used as a reactant in the synthesis of idarubicinone-7-β-D-glucuronides via glucuronidation of idarubicinone with D-glucuronic acid as a key step. Synonyms: NSC 164869; 4-demethoxy-7,9-bisdeoxydaunomycinone; (+/-)-4-demethoxy-7,9-dideoxydaunomycinone; 9-acetyl-6,11-dihydroxy-7,8,9,10-tetrahydronaphthacen-5,12-dione; 9-Acetyl-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,11-dihydroxy-, (±)-; 2-Acetyl-1,2,3,4,6,11-hexahydro-5,12-dihydroxynaphthacene-6,11-quinone; NSC 164869. CAS No. 67122-26-3. Molecular formula: C20H16O5. Mole weight: 336.34. BOC Sciences 5
aclacinomycin-T 2-deoxy-L-fucose transferase The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564. Creative Enzymes

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