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Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC 50 =16.65 μM) [1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells [2]. Idebenone quickly crosses the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. CAS No. 58186-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0303.
Idebenone
Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Synonyms: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. Grade: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44.
Idebenone
Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; Avan; CV 2619; Daruma; Idebenone; Mnesis. Grades: Highly Purified. CAS No. 58186-27-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Idebenone > 98%
Idebenone > 98%. CAS No. 58186-27-9.
CA, FL & NJ
Idebenone-d6
Idebenone-d6 is a labelled Idebenone. Idebenone is a synthetic analogue of coenzyme Q10. It is indicated for the treatment of Alzheimer's disease. Synonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione-d6. Grade: > 95%. Molecular formula: C19H24O5D6. Mole weight: 344.48.
Idebenone-D-Glucuronide
Idebenone-D-Glucuronide is a compound used for studying neurodegenerative ailments, most notably Alzheimer's and Parkinson's. Grade: > 95%. Molecular formula: C25H38O11. Mole weight: 514.58.
Idebenone Glucuronide
Idebenone Glucuronide is the glucuronoside conjugate of Idebenone, an ubiquinone derivative with protective effects against cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid; Avan Glucuronide; CV 2619 Glucuronide; Daruma Glucuronide; Mnesis Glucuronide; Idebenone β-D-Glucuronide. Molecular formula: C25H38O11. Mole weight: 514.56.
The isotope-labelled idebenone glucuronide is a glucuronide conjugate of idebenone. Idebenone is a ubiquinone derivative with protective effects on cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Molecular formula: C24[13C]H35D3O11. Mole weight: 518.57.
Idebenone Impurity8
Idebenone Impurity8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104967-07-9. Molecular formula: C22H34O6. Mole weight: 294.51. Catalog: APB104967079.
Idebenone Impurity9
Idebenone Impurity9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104966-92-9. Molecular formula: C21H32O6. Mole weight: 380.48. Catalog: APB104966929.
Idebenone Sulfate
Idebenone Sulfate is a potent biomedical product used to study the progression of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. It exhibits antioxidant and neuroprotective properties. Synonyms: 10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl hydrogen sulfate; 319906-76-8. Grade: > 95%. CAS No. 319906-76-8. Molecular formula: C19H30O8S. Mole weight: 418.51.
Idebenone Sulfate-13C,d3 Potassium Salt
Idebenone Sulfate-13C,d3 Potassium Salt. Group: Biochemicals. Alternative Names: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1813CH26D3KO8S, Molecular Weight: 460.6. US Biological Life Sciences.
Worldwide
Idebenone Sulfate-13C,d3 Potassium Salt
Isotope labelled Idebenone Sulfate is an analogue of Idebenone. It is an ubiquinone derivative with protective effects against cerebral ischemia. Idebenone Sulfate can be used for skin protection and regenerative purposes. Synonyms: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Molecular formula: C18[13C]H26D3KO8S. Mole weight: 460.6.
Mitochondria-Targeted Compound Library
A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries.
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