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Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC 50 =16.65 μM) [1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells [2]. Idebenone quickly crosses the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. CAS No. 58186-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0303.
Idebenone
Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Synonyms: Idebenone; CV 2619; CV-2619; CV2619; Catena, Raxone, Sovrima. Grades: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44.
Idebenone
Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; Avan; CV 2619; Daruma; Idebenone; Mnesis. Grades: Highly Purified. CAS No. 58186-27-9. Pack Sizes: 100mg. US Biological Life Sciences.
Idebenone Sulfate-13C,d3 Potassium Salt. Group: Biochemicals. Alternative Names: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1813CH26D3KO8S, Molecular Weight: 460.6. US Biological Life Sciences.
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Mitochondria-Targeted Compound Library
A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries.
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