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| Product | Description | |
|---|---|---|
| Imatinib | Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL , v-Abl , PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively [1] [2] [3] [4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-15463. |  |
| Imatinib-D3 | Imatinib-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-18-1. Molecular Formula: C29H28D3N7O. Mole Weight: 496.63. Catalog: APB1134803181. |  |
| Imatinib-D4 | Imatinib-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-16-9. Molecular Formula: C29H27D4N7O. Mole Weight: 497.64. Catalog: APB1134803169. | |
| Imatinib-d8 | Imatinib-d8 is a deuterated tyrosine kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092942-82-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C29H23D8N7O. US Biological Life Sciences. |  Worldwide |
| Imatinib-d8 Methanesulfonate (STI-571-d8, CGP-57148B-d8) | A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Biochemicals. Alternative Names: Imatinib-d8 Methanesulfonate, STI-571-d8, CGP-57148B-d8, Glivec-d8. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Imatinib Dimer Impurity | Imatinib Dimer Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365802-18-1. Molecular Formula: C52H48N12O2. Mole Weight: 873.04. Catalog: APB1365802181. | |
| Imatinib EP Impurity B HCl | Imatinib EP Impurity B HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 581076-67-7. Molecular Formula: C21H29ClN6O. Mole Weight: 416.95. Catalog: APB581076677. | |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1, 4-bis[4-[ (4-methyl-3-[[4- (pyridin-3-yl) pyrimidin-2-yl]amino]phenyl) carbamoyl]benzyl]piperazin-1-ium chloride. Grades: > 95%. CAS No. 1821122-73-9. Molecular formula: C53H51ClN12O2. Mole weight: 923.50. |  |
| Imatinib EP Impurity D | Imatinib EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1821122-73-9. Molecular Formula: C53H51N12O2. Mole Weight: 888.07. Catalog: APB1821122739. | |
| Imatinib EP Impurity F | Cas No. 152460-10-1. | |
| Imatinib EP Impurity H | Imatinib EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 350-03-8. Molecular Formula: C7H7NO. Mole Weight: 121.14. Catalog: APB350038. | |
| Imatinib EP Impurity J | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: Imatinib (Piperidine)-N-oxide; 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 71422; CGP71422; CGP-71422. Grades: > 95%. CAS No. 571186-91-9. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib free base | Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within tyrosine kinases (TK), thereby inhibiting ATP binding and preventing phosphorylation and the subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene as well as receptor TKs encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Imatinib was approved for medical use in the United States in 2001. Group: Inhibitors. Alternative Names: CGP 57148; CGP57148; CGP-57148; CGP57148B; CGP-57148B; CGP 57148B; STI571; STI-571; STI 571. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.62. Appearance: White to off-white to brownish or yellowish tinged crystalline powder. Purity: >98%. IUPACName: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. Canonical SMILES: O=C (NC1=CC=C (C)C (NC2=NC=CC (C3=CC=CN=C3)=N2)=C1)C4=CC=C (CN5CCN (C)CC5)C=C4. Catalog: ACM152459955. |  |
| Imatinib, Free base | An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100ug, 1g. US Biological Life Sciences. | Worldwide |
| Imatinib Guanidine Impurity | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: N-(3-Guanidino-4-methylphenyl)-4-(methylpiperazine-1-yl-methyl)benzamide; N-[3-[(Aminoiminomethyl)amino]-4-methylphenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; N- [2-Methyl-5- [ [4- [ (4-methylpiperazin-1-yl) methyl] benzoyl] amino] phenyl] guanidine. Grades: > 95%. CAS No. 581076-65-5. Molecular formula: C21H28N6O. Mole weight: 380.50. | |
| Imatinib Imidazole Impurity | Imatinib Imidazole Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256080-10-0. Molecular Formula: C32H31N9O2. Mole Weight: 573.66. Catalog: APB1256080100. | |
| Imatinib Impurity 1 | an impurity of Imatinib. Synonyms: Imatinib Diamine N1-Formyl N3-Methyl Impurity; 6-Methyl-N1-formyl-N3-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine. Grades: > 95%. Molecular formula: C18H17N5O. Mole weight: 319.37. | |
| Imatinib Impurity 11 | Imatinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 796738-71-1. Molecular Formula: C16H13N5O2. Mole Weight: 307.31. Catalog: APB796738711. | |
| Imatinib Impurity 12 | Imatinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 112696-91-0. Molecular Formula: C16H15N5. Mole Weight: 277.33. Catalog: APB112696910. | |
| Imatinib Impurity 16 | Imatinib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152460-09-8. Molecular Formula: C16H13N5O2. Mole Weight: 307.31. Catalog: APB152460098. | |
| Imatinib Impurity 17 | Imatinib Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802325-93-4. Molecular Formula: C20H22N2O4. Mole Weight: 354.41. Catalog: APB1802325934. | |
| Imatinib Impurity 18 | Imatinib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 404844-11-7. Molecular Formula: C24H20ClN5O. Mole Weight: 429.91. Catalog: APB404844117. | |
| Imatinib Impurity 2 | an impurity of Imatinib. Synonyms: Imatinib N-Acetyl Impurity; 4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]-N-acetyl-amino}phenyl)benzamide. Grades: > 95%. Molecular formula: C31H33N7O2. Mole weight: 535.65. | |
| Imatinib Impurity 2 | Imatinib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1384131-91-2. Molecular Formula: C7H11NO. Mole Weight: 125.17. Catalog: APB1384131912. | |
| Imatinib Impurity 26 | Imatinib Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 74231-65-5. Molecular Formula: C8H5Cl2N. Mole Weight: 186.04. Catalog: APB74231655. | |
| Imatinib Impurity 27 | Imatinib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67013-55-2. Molecular Formula: C8H5Br2N. Mole Weight: 274.94. Catalog: APB67013552. | |
| Imatinib Impurity 29 | Imatinib Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21900-30-1. Molecular Formula: C8H6Cl2O. Mole Weight: 189.04. Catalog: APB21900301. | |
| Imatinib Impurity 3 | an impurity of Imatinib. Synonyms: 4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide; compound with methanesulfonic acid. Grades: > 95%. Molecular formula: C25H25N5O4S. Mole weight: 491.58. | |
| Imatinib Impurity 3 | Imatinib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152459-96-6. Molecular Formula: C24H21N5O. Mole Weight: 395.47. Catalog: APB152459966. | |
| Imatinib Impurity 30 | Imatinib Impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36747-64-5. Molecular Formula: C8H5Cl3O. Mole Weight: 223.48. Catalog: APB36747645. | |
| Imatinib Impurity 31 | Imatinib Impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1356565-47-3. Molecular Formula: C17H17N7. Mole Weight: 319.37. Catalog: APB1356565473. | |
| Imatinib Impurity 32 | Imatinib Impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16156-50-6. Molecular Formula: C7H16O3S. Mole Weight: 180.26. Catalog: APB16156506. | |
| Imatinib impurity 35 (Hydrochloride) | Imatinib impurity 35 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((4-methylpiperazin-1-yl)methyl)benzoic acid hydrochloride. Molecular Formula: C13H18N2O2·HCl. Mole Weight: 361.31. Catalog: APB01554. | |
| Imatinib impurity 36 | Imatinib impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-methyl-4- (4- ( (4-methyl-3- ( (4- (pyridin-3-yl) pyrimidin-2-yl) amino) phenyl) carbamoyl) benzyl) piperazine 1,4-dioxide. CAS No. 571186-93-1. Molecular Formula: C29H31N7O3. Mole Weight: 525.6. Catalog: APB571186931. | |
| Imatinib Impurity 36 | Imatinib Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106261-48-7. Molecular Formula: C13H18N2O2. Mole Weight: 234.3. Catalog: APB106261487. | |
| Imatinib Impurity 38 | Imatinib Impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5973-83-1. Molecular Formula: C7H8N2O. Mole Weight: 136.15. Catalog: APB5973831. | |
| Imatinib Impurity 4 | an impurity of Imatinib. Synonyms: N-[4-Methyl-3-(4-methyl-6-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide. Grades: > 95%. Molecular formula: C30H33N7O. Mole weight: 507.64. | |
| Imatinib Impurity 4 | Imatinib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 942514-62-7. Molecular Formula: C30H33N7O. Mole Weight: 507.64. Catalog: APB942514627. | |
| Imatinib Impurity 40 | Imatinib Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 581076-66-6. Molecular Formula: C24H19Cl2N5O. Mole Weight: 464.35. Catalog: APB581076666. | |
| Imatinib Impurity 41 | Imatinib Impurity 41. Uses: For analytical and research use. Group: Impurity standards. CAS No. 870459-88-4. Molecular Formula: C8H10N4O2. Mole Weight: 194.19. Catalog: APB870459884. | |
| Imatinib Impurity 5 | an impurity of Imatinib. Synonyms: 4-Methyl-N3-(4-methyl-6-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine. Grades: > 95%. Molecular formula: C17H17N5. Mole weight: 291.36. | |
| Imatinib Impurity 5 | Imatinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1032314-73-0. Molecular Formula: C17H17N5. Mole Weight: 291.36. Catalog: APB1032314730. | |
| Imatinib Impurity 53 | Imatinib Impurity 53. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1356565-46-2. Molecular Formula: C42H47N9O2. Mole Weight: 709.9. Catalog: APB1356565462. | |
| Imatinib Impurity 59 | Imatinib Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 796738-72-2. Molecular Formula: C8H10N4O2. Mole Weight: 194.19. Catalog: APB796738722. | |
| Imatinib Impurity 6 | Imatinib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1349250-06-1. Molecular Formula: C29H31N7O. Mole Weight: 493.61. Catalog: APB1349250061. | |
| Imatinib Impurity 6 | Intermediate in the preparation of Imatinib impurities. Synonyms: N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine; 3-Methyl-4-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline; 2-Methyl-N1-[4-(3-pyridinyl)-2-pyrimidinyl]-1,4-benzenediamine. Grades: > 95%. CAS No. 112696-91-0. Molecular formula: C16H15N5. Mole weight: 277.33. | |
| Imatinib Impurity 62 | Imatinib Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 314268-40-1. Molecular Formula: C14H20N2O2. Mole Weight: 248.33. Catalog: APB314268401. | |
| Imatinib Impurity 67 | Imatinib Impurity 67. Uses: For analytical and research use. Group: Impurity standards. CAS No. 7115-89-1. Molecular Formula: C8H7BrO2. Mole Weight: 215.05. Catalog: APB7115891. | |
| Imatinib Impurity 7 | Imatinib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 581076-64-4. Molecular Formula: C8H12N4. Mole Weight: 164.21. Catalog: APB581076644. | |
| Imatinib Impurity 7 | Intermediate in the preparation of Imatinib impurities. Synonyms: N-(5-Amino-2-methylphenyl)guanadine. Grades: > 95%. CAS No. 581076-64-4. Molecular formula: C8H12N4. Mole weight: 164.21. | |
| Imatinib Impurity 8 | an impurity of Gleevec. Synonyms: Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde; N-(2-Methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenyl)-4-((4-methylpiperazin-1-yl)methyl)-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide. Grades: > 95%. CAS No. 1356565-46-2. Molecular formula: C42H47N9O2. Mole weight: 709.90. | |
| Imatinib Impurity 8 | Imatinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1407229-73-5. Molecular Formula: C21H25N2O4+. Mole Weight: 369.44. Catalog: APB1407229735. | |
| Imatinib Impurity 9 | Intermediate in the preparation of Imatinib impurities. Synonyms: 1,4-Bis-(4-carboxy-benzyl)-1-methyl-piperazin-1-ium. Grades: > 95%. Molecular formula: C21H25N2O4. Mole weight: 369.44. | |
| Imatinib impurity A | Imatinib impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-guanidino-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. CAS No. 581076-65-5. Molecular Formula: C21H28N6O. Mole Weight: 380.49. Catalog: APB581076655. | |
| Imatinib Impurity A | an impurity of Imatinib (Gleevec). Synonyms: N-[4-Methyl-3-[[4-(1-oxido-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; CGP 72383. Grades: > 95%. CAS No. 571186-92-0. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib impurity B | Imatinib impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide. CAS No. 404844-02-6. Molecular Formula: C28H29N7O. Mole Weight: 479.58. Catalog: APB404844026. | |
| Imatinib impurity C | Imatinib impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-methyl-1, 4-bis (4- ( (4-methyl-3- ( (4- (pyridin-3-yl) pyrimidin-2-yl) amino) phenyl) carbamoyl) benzyl) piperazin-1-ium. Molecular Formula: C53H51N12O2+. Mole Weight: 888.05. Catalog: APB02181. | |
| Imatinib Impurity C | an impurity of Imatinib (Gleevec). Synonyms: Imatinib (Piperidine)-1-oxide; 4-[(4-Methyl-1-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 938082-57-6. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib impurity D | Imatinib impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine. CAS No. 152460-10-1. Molecular Formula: C16H15N5. Mole Weight: 277.32. Catalog: APB152460101. | |
| Imatinib Impurity E | an impurity of Imatinib (Gleevec). Synonyms: Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity; 4,4'-(piperazine-1,4-diylbis(methylene))bis(N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide). Grades: > 95%. CAS No. 1365802-18-1. Molecular formula: C52H48N12O2. Mole weight: 873.04. | |
| Imatinib Impurity H | an impurity of Imatinib, a tyrosine kinase inhibitor. Synonyms: Imatinib para-Diaminomethylbenzene; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 1026753-54-7. Molecular formula: C29H31N7O. Mole weight: 493.62. | |
| Imatinib impurity I | Imatinib impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-methyl-4- (4- ( (4-methyl-3- ( (4- (pyridin-3-yl) pyrimidin-2-yl) amino) phenyl) carbamoyl) benzyl) piperazine 1-oxide. CAS No. 571186-91-9. Molecular Formula: C29H31N7O2. Mole Weight: 509.6. Catalog: APB571186919. | |
| Imatinib impurity J | Imatinib impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one. CAS No. 123367-26-0. Molecular Formula: C10H12N2O. Mole Weight: 176.22. Catalog: APB123367260. | |
| Imatinib Impurity K | Imatinib Impurity K. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2410195-20-7. Molecular Formula: C17H15N5O. Mole Weight: 305.34. Catalog: APB2410195207. | |
| Imatinib Impurity M | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: 1,4-Bis(4-carboxybenzyl)-1-methylpiperazin-1-ium (Imatinib Impurity); 1,4-BIS(4-CARBOXYBENZYL)-1-METHYLPIPERAZIN-1-IUM; Imatinib Impurity M; SCHEMBL14646970; CS-0255288; F83280. CAS No. 1407229-73-5. Molecular formula: C21H25N2O4+. Mole weight: 369.44. | |
| Imatinib Impurity X | Imatinib Impurity X. Uses: For analytical and research use. Group: Impurity standards. CAS No. 75415-01-9. Molecular Formula: C10H12N2O. Mole Weight: 176.22. Catalog: APB75415019. | |
| Imatinib Intermediate 1 | Imatinib Intermediate 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125743-63-7. Molecular Formula: C13H17N3. Mole Weight: 215.3. Catalog: APB125743637. | |
| Imatinib Intermediate 2 | Imatinib Intermediate 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106261-49-8. Molecular Formula: C13H20Cl2N2O2. Mole Weight: 307.22. Catalog: APB106261498. | |
| Imatinib Intermediate 3 | Imatinib Intermediate 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1407124-83-7. Molecular Formula: C16H13N5O. Mole Weight: 291.31. Catalog: APB1407124837. | |
| Imatinib Intermediate 4 | Imatinib Intermediate 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 86620-81-7. Molecular Formula: C13H18N2O2. Mole Weight: 234.3. Catalog: APB86620817. | |
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