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| Product | Description | |
|---|---|---|
| inositol-1,4-bisphosphate 1-phosphatase | The enzyme acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar Vmax values for both substrates, but with a five-times higher affinity for the bisphosphate. Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate. Group: Enzymes. Synonyms: inositol-polyphosphate 1-phosphatase. Enzyme Commission Number: EC 3.1.3.57. CAS No. 111070-17-8, 111694-13-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3662; inositol-1,4-bisphosphate 1-phosphatase; EC 3.1.3.57; 111070-17-8, 111694-13-4; inositol-polyphosphate 1-phosphatase. Cat No: EXWM-3662. |  |
| inositol-phosphate phosphatase | Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo-inositol bearing more than one phosphate group. It also acts on adenosine 2'-phosphate (but not the 3'- or 5'- phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate. Two isoforms are known. Group: Enzymes. Synonyms: myo-inositol-1(or 4)-monophosphatase; inositol 1-phosphatase; L-myo-inositol-1-phosphate phosphatase; myo-inositol 1-phosphatase; inositol phosphatase; inositol monophosphate phosphatase; inositol-1(or 4)-monophosphatase; myo-inositol-1(or 4)-phosphate phosphohydrolase; myo-inositol monophosphatase; myo-inositol-1-phosphatase. Enzyme Commission Number: EC 3.1.3.25. CAS No. 37184-63-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3628; inositol-phosphate phosphatase; EC 3.1.3.25; 37184-63-7; myo-inositol-1(or 4)-monophosphatase; inositol 1-phosphatase; L-myo-inositol-1-phosphate phosphatase; myo-inositol 1-phosphatase; inositol phosphatase; inositol monophosphate phosphatase; inositol-1(or 4)-monophosphatase; myo-inositol-1(or 4)-phosphate phosphohydrolase; myo-inositol monophosphatase; myo-inositol-1-phosphatase. Cat No: EXWM-3628. | |
| inositol-polyphosphate 5-phosphatase | One mammalian isoform is known. This enzyme is distinguished from the family of enzymes classified under EC 3.1.3.36, phosphoinositide 5-phosphatase, by its inability to dephosphorylate inositol lipids. Group: Enzymes. Synonyms: type I inositol-polyphosphate phosphatase; inositol trisphosphate phosphomonoesterase; InsP3/Ins(1,3,4,5)P4 5-phosphatase; inosine triphosphatase; D-myo-inositol 1,4,5-triphosphate 5-. Enzyme Commission Number: EC 3.1.3.56. CAS No. 106283-14-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3661; inositol-polyphosphate 5-phosphatase; EC 3.1.3.56; 106283-14-1; type I inositol-polyphosphate phosphatase; inositol trisphosphate phosphomonoesterase; InsP3/Ins(1,3,4,5)P4 5-phosphatase; inosine triphosphatase; D-myo-inositol 1,4,5-triphosphate 5-phosphatase; D-myo-inositol 1,4,5-trisphosphate 5-phosphatase; L-myo-inositol 1,4,5-trisphosphate-monoesterase; inositol phosphate 5-phosphomonoesterase; inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase; Ins(1,4,5)P3 5-phosphatase; D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase; inositol 1,4,5-trisphosphate phosphatase; inositol polyphosphate-5-phosphatase; myo-inositol-1,4,5-trisphosphate 5-phosphatase; inositol-1,4,5-trisphosphate 5-phosphatase. Cat No: EXWM-3661. | |
| multiple inositol-polyphosphate phosphatase | This enzyme exists in two isoforms. It also acts on Ins(1,3,4,5)P4 to yield Ins(1,4,5)P3. Group: Enzymes. Synonyms: inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase; inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase; inositol tetrakisphosphate phosphomonoesterase; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase; MIPP. Enzyme Commission Number: EC 3.1.3.62. CAS No. 116958-30-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3667; multiple inositol-polyphosphate phosphatase; EC 3.1.3.62; 116958-30-6; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase; inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase; inositol tetrakisphosphate phosphomonoesterase; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase; MIPP. Cat No: EXWM-3667. | |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase | Requires Mg2+. Does not dephosphorylate inositol 4,5-bisphosphate. This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyses Ins(1,3,4,5)P4 to Ins(1,4,5)P3. Group: Enzymes. Synonyms: PTEN; MMAC1; phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase. Enzyme Commission Number: EC 3.1.3.67. CAS No. 210488-47-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3671; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase; EC 3.1.3.67; 210488-47-4; PTEN; MMAC1; phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase. Cat No: EXWM-3671. | |
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase | This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. The enzyme also shows activity toward (PtdIns(1,3,4,5)P4). The enzyme is involved in several signal transduction pathways in the immune system leading to an adverse range of effects. Group: Enzymes. Synonyms: SHIP1; SHIP2; SHIP; p150Ship. Enzyme Commission Number: EC 3.1.3.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3692; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; EC 3.1.3.86; SHIP1; SHIP2; SHIP; p150Ship. Cat No: EXWM-3692. | |
| phosphatidylinositol-3,4-bisphosphate 4-phosphatase | Mg2+-independent. This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyses Ins(1,3,4)P3 to Ins(1,3)P2. It also converts Ins(3,4)P2 into Ins-3-P. Group: Enzymes. Synonyms: inositol-3,4-bisphosphate 4-phosphatase; D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase; phosphoinositide 4-phosphatase; inositol polyphosphate 4-phosphatase; inositol polyphosphate 4-phosphatase type II. Enzyme Commission Number: EC 3.1.3.66. CAS No. 123644-80-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3670; phosphatidylinositol-3,4-bisphosphate 4-phosphatase; EC 3.1.3.66; 123644-80-4; inositol-3,4-bisphosphate 4-phosphatase; D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase; phosphoinositide 4-phosphatase; inositol polyphosphate 4-phosphatase; inositol polyphosphate 4-phosphatase type II. Cat No: EXWM-3670. | |
| phosphatidylinositol-4,5-bisphosphate 4-phosphatase | Two pathways exist in mammalian cells to degrade 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [PtdIns(4,5)P2]. One is catalysed by this enzyme and the other by EC 3.1.3.36, phosphoinositide 5-phosphatase, where the product is PtdIns4P. The enzyme from human is specific for PtdIns(4,5)P2 as substrate, as it cannot use PtdIns(3,4,5)P3, PtdIns(3,4)P2, PtdIns(3,5)P2, PtdIns5P, PtdIns4P or PtdIns3P. In humans, the enzyme is localized to late endosomal/lysosomal membranes. It can control nuclear levels of PtdIns5P and thereby control p53-dependent apoptosis. Group: Enzymes. Synonyms: phosphatidylinositol-4,5-bisphosphate 4-phosphatase I; phosphatidylinositol-4,5-bisphosphate 4-phosphatase II; type I PtdIns-4,5-P2 4-Ptase; type II PtdIns-4,5-P2 . Enzyme Commission Number: EC 3.1.3.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3683; phosphatidylinositol-4,5-bisphosphate 4-phosphatase; EC 3.1.3.78; phosphatidylinositol-4,5-bisphosphate 4-phosphatase I; phosphatidylinositol-4,5-bisphosphate 4-phosphatase II; type I PtdIns-4,5-P2 4-Ptase; type II PtdIns-4,5-P2 4-Ptase; IpgD; PtdIns-4,5-P2 4-phosphatase type I; PtdIns-4,5-P2 4-phosphatase type II; type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase; type 1 4-phosphatase. Cat No: EXWM-3683. | |
| 2,3-bisphosphoglycerate 3-phosphatase | This reaction is a shortcut in the Rapoport-Luebering shunt. It bypasses the reactions of EC 3.1.3.13/EC 5.4.2.12 [bisphosphoglycerate phosphatase/phosphoglycerate mutase (2,3-diphosphoglycerate-independent)] and directly forms 2-phospho-D-glycerate by removing the 3-phospho-group of 2,3-diphospho-D-glycerate. The MIPP1 protein also catalyses the reaction of EC 3.1.3.62 (multiple inositol-polyphosphate phosphatase). Group: Enzymes. Synonyms: MIPP1; 2,3-BPG 3-phosphatase. Enzyme Commission Number: EC 3.1.3.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3686; 2,3-bisphosphoglycerate 3-phosphatase; EC 3.1.3.80; MIPP1; 2,3-BPG 3-phosphatase. Cat No: EXWM-3686. | |
| 3-phytase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-hexakisphosphate 3-phosphohydrolase. Other names in common use include 1-phytase, phytase, phytate 1-phosphatase, and phytate 6-phosphatase. This enzyme participates in inositol phosphate metabolism. Group: Enzymes. Synonyms: 1-phytase; phytase; phytate 1-phosphatase; phytate 6-phosphatase. Enzyme Commission Number: EC 3.1.3.8. CAS No. 37288-11-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3685; 3-phytase; EC 3.1.3.8; 37288-11-2; 1-phytase; phytase; phytate 1-phosphatase; phytate 6-phosphatase. Cat No: EXWM-3685. | |
| 4-phytase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-hexakisphosphate 6-phosphohydrolase. Other names in common use include 6-phytase (name based on 1L-numbering system and not 1D-numbering), phytase, and phytate 6-phosphatase. This enzyme participates in inositol phosphate metabolism. Group: Enzymes. Synonyms: 6-phytase (name based on 1L-numbering system and not 1D-numbering); phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase (name based on 1L-numbering system and not 1D-numbering). Enzyme Commission Number: EC 3.1.3.26. CAS No. 9001-89-2. Phytase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3629; 4-phytase; EC 3.1.3.26; 9001-89-2; 6-phytase (name based on 1L-numbering system and not 1D-numbering); phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase (name based on 1L-numbering system and not 1D-numbering). Cat No: EXWM-3629. | |
| AR 244555 | AR 244555 is an inverse agonist of Mas G-protein signaling (IC50 values 186 and 348 nM in human and rat inositol phosphatase (IP) Gq coupling assays respectively). AR 244555 inhibited inositol 1,4,5-trisphosphate accumulation in AdMas-infected cells and attenuated the sarcomeric organization and cell enlargement observed in Mas overexpressing myocytes. AR 244555 caused an increase in coronary flow in rat hearts without causing arrhythmias, and provides protection from ischemia-reperfusion injury if administered either before ischemia or immediately before reperfusion. Synonyms: AR244555; AR 244555; AR-244555; (1'-but-3-enyl-5-chlorospiro[2H-indole-3,4'-piperidine]-1-yl)-(2,6-difluorophenyl)methanone. Grades: 99%. CAS No. 858350-62-6. Molecular formula: C23H23ClF2N2O. Mole weight: 416.89. |  |
| D-galactose 1-phosphate phosphatase | The human enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzyme has very low activity with L-galactose 1-phosphate (cf. EC 3.1.3.93, L-galactose 1-phosphate phosphatase). Group: Enzymes. Enzyme Commission Number: EC 3.1.3.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3701; D-galactose 1-phosphate phosphatase; EC 3.1.3.94. Cat No: EXWM-3701. | |
| diacylglycerol diphosphate phosphatase | The bifunctional enzyme catalyses the dephosphorylation of diacylglycerol diphosphate to phosphatidate and the subsequent dephosphorylation of phosphatidate to diacylglycerol (cf. phosphatidate phosphatase (EC 3.1.3.4)). It regulates intracellular levels of diacylglycerol diphosphate and phosphatidate, phospholipid molecules believed to play a signalling role in stress response. The phosphatase activity of the bifunctional enzyme is Mg2+-independent and N-ethylmaleimide-insensitive and is distinct from the Mg2+-dependent and N-ethylmaleimide-sensitive enzyme EC 3.1.3.4 (phosphatidate phosphatase).The diacylglycerol pyrophosphate phosphatase activity in Saccharomyces cerevisiae is induced by zinc depletion, by inositol supplementation, and when cells enter the stationary phase. Group: Enzymes. Synonyms: DGPP phosphatase; DGPP phosphohydrolase; DPP1; DPPL1; DPPL2; PAP2; pyrophosphate phosphatase. Enzyme Commission Number: EC 3.1.3.81. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3687; diacylglycerol diphosphate phosphatase; EC 3.1.3.81; DGPP phosphatase; DGPP phosphohydrolase; DPP1; DPPL1; DPPL2; PAP2; pyrophosphate phosphatase. Cat No: EXWM-3687. | |
| D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt | D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt is the octapotassium salt of D-myo-Inositol-1,3,4,5-tetrakisphosphate, which is the phosphorylation product of inositol 1,4,5-trisphosphate and the enantiomer of the naturally-occurring D-myo-inositol 1,3,4,5-tetrakisphosphate. It is a potent inhibitor of Ins (1,4,5)P3 5-phosphatase with IC50 value of ~150 nM. It facilitates Ca2+ influx by sensitizing Ins (1,4,5)P3-mediated activation of ICRAC. It is a useful intermediate. Synonyms: L-myo-Inositol 1,3,4,5-(tetrakis)phosphate potassium salt. Grades: ≥98% by HPLC. CAS No. 145843-69-2. Molecular formula: C6H8O18P4K8. Mole weight: 804.73. | |
| inositol-tetrakisphosphate 1-kinase | This enzyme also phosphorylates Ins(1,3,4)P3 on O-5 and O-6. The phosphotransfer from ATP to either inositol 1,3,4-trisphosphate or inositol 3,4,5,6-tetrakisphosphate appears to be freely reversible to the extent that the enzyme can act like an inositol polyphosphate phosphatase in the presence of ADP. It can also catalyse an isomerization between Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP. Group: Enzymes. Synonyms: 1D-myo-inositol-tetrakisphosphate 1-kinase; inositol-trisphosphate 6-kinase; 1D-myo-inositol-trisphosphate 6-kinase; ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase; inositol-trisphosphate 5-kinase; 1D-myo-inositol-trisphosphate 5-kinase; ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase. Enzyme Commission Number: EC 2.7.1.134. CAS No. 187175-98-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2966; inositol-tetrakisphosphate 1-kinase; EC 2.7.1.134; 187175-98-0; 1D-myo-inositol-tetrakisphosphate 1-kinase; inositol-trisphosphate 6-kinase; 1D-myo-inositol-trisphosphate 6-kinase; ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase; inositol-trisphosphate 5-kinase; 1D-myo-inositol-trisphosphate 5-kinase; ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase. Cat No: EXWM-2966. | |
| L-galactose 1-phosphate phosphatase | The enzyme from plants also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzymes have very low activity with D-galactose 1-phosphate (cf. EC 3.1.3.94, D-galactose 1-phosphate phosphatase). Group: Enzymes. Synonyms: VTC4 (gene name) (ambiguous); IMPL2 (gene name) (ambiguous). Enzyme Commission Number: EC 3.1.3.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3700; L-galactose 1-phosphate phosphatase; EC 3.1.3.93; VTC4 (gene name) (ambiguous); IMPL2 (gene name) (ambiguous). Cat No: EXWM-3700. | |
| Native Wheat Phytase | Phytase catalyzes the hydrolysis of phytic acid to inositol and free orthophosphate. Wheat phytase can degrade inositol phosphate-6 and 5 at a pH of 4 and 5. Phytase catalyzes the hydrolysis of phytic acid to inositol and free orthophosphate. Applications: Phytase has been used in a study to quantify the number of feedstuffs showing significant phytase activity. it has also been used in a study to investigate the effect of adjusting the ph to 5.0 (optimum for wheat phytase) during whole wheat bread making on phytase activity. Group: Enzymes. Synonyms: myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Enzyme Commission Number: EC 3.1.3.26. CAS No. 9001-89-2. Phytase. Activity: 0.01-0.04 unit/mg solid. Storage: -20°C. Source: Wheat. myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Cat No: NATE-0566. | |
| Native Yeast Phytase | Phytase catalyzes the hydrolysis of phytic acid to inositol and free orthophosphate. Wheat phytase can degrade inositol phosphate-6 and 5 at a pH of 4 and 5. Group: Enzymes. Synonyms: myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Enzyme Commission Number: EC 3.1.3.26. CAS No. 9001-89-2. Phytase. Activity: 5000 u/g. Storage: Store at -20°C. Form: Powder. Source: Yeast. myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Cat No: NATE-0565. | |
| phosphatidylinositol-3-phosphatase | This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyses Ins(1,3)P2 to Ins-1-P. Group: Enzymes. Synonyms: inositol-1,3-bisphosphate 3-phosphatase; inositol 1,3-bisphosphate phosphatase; inositol-polyphosphate 3-phosphatase; D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase; phosphatidyl-3-phosphate 3-phosphohydrolase. Enzyme Commission Number: EC 3.1.3.64. CAS No. 124248-47-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3669; phosphatidylinositol-3-phosphatase; EC 3.1.3.64; 124248-47-1; inositol-1,3-bisphosphate 3-phosphatase; inositol 1,3-bisphosphate phosphatase; inositol-polyphosphate 3-phosphatase; D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase; phosphatidyl-3-phosphate 3-phosphohydrolase. Cat No: EXWM-3669. | |
| phosphoinositide 5-phosphatase | These enzymes can also remove the 5-phosphate from Ins(1,4,5)P3 and/or Ins(1,3,4,5)P4. They are a diverse family of enzymes, with differing abilities to catalyse two or more of the four reactions listed. They are thought to use inositol lipids rather than inositol phosphates as substrates in vivo. All of them can use either or both of PtdIns(4,5)P2 and PtdIns(3,4,5)P3 as substrates; this is the main property that distinguishes them from EC 3.1.3.56, inositol-polyphosphate 5-phosphatase. Group: Enzymes. Synonyms: type II inositol polyphosphate 5-phosphatase; triphosp. Enzyme Commission Number: EC 3.1.3.36. CAS No. 9036-1-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3639; phosphoinositide 5-phosphatase; EC 3.1.3.36; 9036-01-5; type II inositol polyphosphate 5-phosphatase; triphosphoinositide phosphatase; IP3 phosphatase; PtdIns(4,5)P2 phosphatase; triphosphoinositide phosphomonoesterase; diphosphoinositide phosphatase; inositol 1,4,5-triphosphate 5-phosphomonoesterase; inositol triphosphate 5-phosphomonoesterase; phosphatidylinositol-bisphosphatase; phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase; phosphatidylinositol 4,5-bisphosphate phosphatase; polyphosphoinositol lipid 5-phosphatase; phosphatidyl-inositol-bisphosphate phosphatase. Cat No: EXWM-3639. | |
| PHYTASE | PHYTASE. Synonyms: PHYTASE CRUDE, FROM WHEAT;phytase from wheat;6-Phytase, myo-Inositol-hexakisphosphate 6-phosphohydrolase, Phytate 6-phosphatase;Phytase from wheat,6-Phytase, Phytate 6-phosphatase, myo-Inositol-hexakisphosphate 6-phosphohydrolase;Phosphatase, phytate 6-;6-PHYTASE;phylase;MYO-INOSITOLHEXAKISPHOSPHATE 3-PHOSPHOHYDROLASE. CAS No. 9001-89-2. Pack Sizes: 1 kg. Product ID: CDF4-0058. Molecular formula: NULL. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; PHYTASE; CDF4-0058; 9001-89-2; 629-845-9; 9001-89-2. Purity: 0.98. EC Number: 629-845-9. Storage: -20°C. Application: Phytase has been used in a study to quantify the number of feedstuffs showing significant phytase activity. It has also been used in a study to investigate the effect of adjusting the pH to 5.0 (optimum for wheat phytase) during whole wheat bread making on phytase activity. Density: 1.33-1.42g/cm3 at 20°C. Product Description: Phytase catalyzes the hydrolysis of phytic acid to inositol and free orthophosphate. |  |
| 3α-Aminocholestane | 3α-Aminocholestane is an inhibitor of SH2 domain-containing inositol-5'-phosphatase 1 (SHP-1; IC50=~2.5 μM). It is selective for SHP-1 over SHP-2 and phosphatase and tensin homolog (PTEN; IC50s=>20 μM). Synonyms: 3AC; 5alpha-Cholestane-3alpha-amine. Grades: ≥95%. CAS No. 2206-20-4. Molecular formula: C27H49N. Mole weight: 387.7. | |
| bpV(phen) potassium hydrate | BpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 38 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 343 nM and PTP-1β with IC50 of 920 nM. At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. Synonyms: Bisperoxovanadium(phen); Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Grades: ≥98%. CAS No. 171202-16-7. Molecular formula: C12H8N2O5V·K+(H2O)3. Mole weight: 404.3. | |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. |  |
| D-myo-Inositol-1,4,5-triphosphate hexasodium salt | IP3 analog, resistant to metabolic enzymes, features an extended duration of action. It resists IP3 kinase and potently inhibits 5-phosphatase. CAS No. 108340-81-4. Product ID: 3-00096. Molecular formula: C6H9O15P3. (IP3). Mole weight: 552. Purity: 0.99. Source : |  |
| guanidinodeoxy-scyllo-inositol-4-phosphatase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. Group: Enzymes. Synonyms: 1-guanidino-scyllo-inositol 4-phosphatase; 1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase. Enzyme Commission Number: EC 3.1.3.40. CAS No. 9055-28-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3644; guanidinodeoxy-scyllo-inositol-4-phosphatase; EC 3.1.3.40; 9055-28-1; 1-guanidino-scyllo-inositol 4-phosphatase; 1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase. Cat No: EXWM-3644. | |
| Potassium Bisperoxo (pyridine-2-carboxylato) oxovanadate | A novel Vanadium compound use as inhibitor of phosphatases, particularly inositol phosphatases. Used in the treatment of neurodegenerative diseases. Has antineoplastoc activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 68782-46-7. Pack Sizes: 250mg. US Biological Life Sciences. |  Worldwide |
| SHIP1 Inhibitor, 3AC (SH2-domain-containing inositol 5-phosphatase 1 (SHIP1) Inhibitor, 3AC, 3a-Aminocholestane) | A cell-permeable steroidal compound that acts as a highly selective SHIP1 activity inhibitor (IC50=10uM) over SHIP2 and PTEN (IC50>1mM in a phosphate release assay). Shown to boost the number of myeloid immunoregulatory cells and circulating granulocytes, and facilitate blood cell recovery in myelosuppressed hosts (60uM, i.p. in mice). Also, promotes apoptosis and reduces SHIP1-expressing KG1 and C1498 cell growth. SHIP2 Inhibitor, AS1938909 is also available. Group: Biochemicals. Grades: Highly Purified. CAS No. 2206-20-4. Pack Sizes: 10mg. Molecular Formula: C??H??N. US Biological Life Sciences. | Worldwide |
| SHIP2 Inhibitor, AS1938909 (3- (2, 4-Dichlorobenzyl) oxy]-N- (2, 6-difluorobenzyl) thiophene-2-carboxamide, SH2 Domain-containing Inositol 5-phosphatase 2 (SHIP2) Inhibitor) | A cell-permeable thiophenecarboxamide compound that is shown to increase glucose metabolism and activate intracellular insulin signaling. Acts as a potent, competitive and reversible inhibitor of SHIP2 activity (Ki=0.44uM for hSHIP2) with moderate to excellent selectivity over SHIP1 and other related phosphatases (IC50=0.18, 0.57, 21, >50, >50 and >50uM for mSHIP2, hSHIP2, hSHIP1, hPTEN, h-synaptojanin and h-myotubularin, respectively). Elevates insulin-induced pAkt-Ser473 levels and enhances glucose transporter GLUT1 mRNA expression in L6 myotubes. SHIP1 Inhibitor, 3AC is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SHIP2 Inhibitor II, CPDA | A cell-permeable aminopyridine acetamide based compound that acts as an inhibitor of SH2 domain-containing inositol 5-phosphatase 2 (SHIP2) that can overcome insulin resistance in 3T3-L1 adipocytes. Enhances insulin-stimulated Akt phosphorylation (Thr308) in TNFa-treated 3T3-L1 adipocytes (~10uM) and in primary cultured neurons from rat cerebral cortex. Improves glucose tolerance in db/db mice (~300mg/kg b.i.d) without affecting their fasting glucose levels. Also reduces the expression levels of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?O?, Primary Target: SHIP2. US Biological Life Sciences. | Worldwide |
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