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| Product | Description | |
|---|---|---|
| Insulin aspart | Insulin aspart (B28Asp) is a fast-acting analog of human insulin. Insulin aspart provides more rapid absorption than regular human insulin after subcutaneous administration. Insulin aspart can be used for researching diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: B28Asp; B28-Asp-insulin; INA-X 14; Insulin X 14. CAS No. 116094-23-6. Pack Sizes: 100 U; 300 U. Product ID: HY-108767. |  |
| Insulin aspart | Insulin aspart is an insulin analog that functions faster and lasts for a shorter time than regular insulin. Insulin aspart has been indicated for the treatment of type 1 and type 2 diabetes. Synonyms: DL-phenylalanyl-DL-valyl-DL-asparagyl-DL-glutaminyl-DL-histidyl-DL-leucyl-DL-cysteinyl-glycyl-DL-seryl-DL-histidyl-DL-leucyl-DL-valyl-DL-alpha-glutamyl-DL-alanyl-DL-leucyl-DL-tyrosyl-DL-leucyl-DL-valyl-DL-cysteinyl-glycyl-DL-alpha-glutamyl-DL-arginyl-glycyl-DL-phenylalanyl-DL-phenylalanyl-DL-tyrosyl-DL-threonyl-DL-alpha-aspartyl-DL-lysyl-DL-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-DL-isoleucyl-DL-valyl-DL-alpha-glutamyl-DL-glutaminyl-DL-cysteinyl-DL-cysteinyl-DL-threonyl-DL-seryl-DL-isoleucyl-DL-cysteinyl-DL-seryl-DL-leucyl-DL-tyrosyl-DL-glutaminyl-DL-leucyl-DL-alpha-glutamyl-DL-asparagyl-DL-tyrosyl-DL-cysteinyl-DL-asparagine (6'->11')-disulfide; H-DL-Phe-DL-Val-DL-Asn-DL-Gln-DL-His-DL-Leu-DL-Cys(1)-Gly-DL-Ser-DL-His-DL-Leu-DL-Val-DL-Glu-DL-Ala-DL-Leu-DL-Tyr-DL-Leu-DL-Val-DL-Cys(2)-Gly-DL-Glu-DL-Arg-Gly-DL-Phe-DL-Phe-DL-Tyr-DL-xiThr-DL-Asp-DL-Lys-DL-xiThr-OH.H-Gly-DL-xiIle-DL-Val-DL-Glu-DL-Gln-DL-Cys(3)-DL-Cys(1)-DL-xiThr-DL-Ser-DL-xiIle-DL-Cys(3)-DL-Ser-DL-Leu-DL-Tyr-DL-Gln-DL-Leu-DL-Glu-DL-Asn-DL-Tyr-DL-Cys(2)-DL-Asn-OH. CAS No. 116094-23-6. Molecular formula: C256H381N65O79S6. Mole weight: 5825.53. |  |
| Insulin Aspart EP/USP | antagonist of histamine H1 and platelet-activating factor receptors. Grades: EP/USP. CAS No. 116094-23-6. Product ID: 8-04757. Molecular formula: C256H381N65O79S6. Mole weight: 5825.59. |  |
| Adropin (34-76) (human, mouse, rat) | Adropin, a secreted factor involved in energy homeostasis and lipid metabolism, is encoded by the energy homeostasis-related gene (Enho) and expressed in the liver and brain. In diet-induced obesity (DIO) mice, adropin (34-76) reduced hepatosteatosis and insulin resistance, regardless of obesity or food intake. In addition, adropin could be a regulator of endothelial function. Synonyms: H-Cys-His-Ser-Arg-Ser-Ala-Asp-Val-Asp-Ser-Leu-Ser-Glu-Ser-Ser-Pro-Asn-Ser-Ser-Pro-Gly-Pro-Cys-Pro-Glu-Lys-Ala-Pro-Pro-Pro-Gln-Lys-Pro-Ser-His-Glu-Gly-Ser-Tyr-Leu-Leu-Gln-Pro-OH (Disulfide bridge: Cys1-Cys23); L-Cysteinyl-L-histidyl-L-seryl-L-arginyl-L-seryl-L-alanyl-L-alpha-aspartyl-L-valyl-L-alpha-aspartyl-L-seryl-L-leucyl-L-seryl-L-alpha-glutamyl-L-seryl-L-seryl-L-prolyl-L-asparaginyl-L-seryl-L-seryl-L-prolylglycyl-L-prolyl-L-cysteinyl-L-prolyl-L-alpha-glutamyl-L-lysyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-glutaminyl-L-lysyl-L-prolyl-L-seryl-L-histidyl-L-alpha-glutamylglycyl-L-seryl-L-tyrosyl-L-leucyl-L-leucyl-L-glutaminyl-L-proline cyclic (1?23)-disulfide. Grades: ≥95%. CAS No. 1802086-30-1. Molecular formula: C190H293N55O68S2. Mole weight: 4499.82. | |
| Axltide | Axltide is based on mouse insulin receptor substrate 1 (amino acids 979-989). It is also a substrate for the kinases AXL, DDR2, MST1 and JAK2. Synonyms: Axl/Insulin Receptor Substrate Peptide; H-Lys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Met-Gln-Ile-Gly-OH; L-lysyl-L-lysyl-L-seryl-L-arginyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-methionyl-L-threonyl-L-methionyl-L-glutaminyl-L-isoleucyl-glycine. Grades: ≥98%. CAS No. 143364-95-8. Molecular formula: C63H107N19O20S2. Mole weight: 1514.77. | |
| CJC1295 Without DAC | CJC-1295 is a 30-amino acid peptide and a growth hormone releasing hormone (GHRH) analog. It prolongs stimulation of growth hormone (GH) and insulin-like growth factor I secretion. It also extends the half-life and bioavailability of growth-hormone-releasing hormone 1-29. Synonyms: CJC 1295; CJC1295; L-tyrosyl-D-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide. Grades: >98%. CAS No. 863288-34-0. Molecular formula: C152H252N44O42. Mole weight: 3367.9. | |
| C-Peptide 1 (rat) | C-Peptide 1 (rat) specifically binds to G-protein-coupled membrane receptors in the nanomolar concentration range, and subsequently activates Ca2+-dependent intracellular signaling pathways. This leads to a stimulation of the activity of both Na+-K+-ATPase, and endothelial nitric oxide synthase. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. Synonyms: Insulin 1 Precursor (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-prolyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-L-alpha-glutamyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine. Grades: ≥95%. CAS No. 41475-27-8. Molecular formula: C140H228N38O51. Mole weight: 3259.53. | |
| C-Peptide 2 (rat) | C-Peptide 2 (rat), a peptide composed of 31 amino acid residues, can effectively improve glucose utilization in streptozotocin induced diabetic rats. It is a component of proinsulin, and can inhibit glucose-induced insulin secretion. Synonyms: Preproinsulin 2 (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Ala-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-alanyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine; Insulin 2 Precursor (57-87) (rat); Proinsulin 2 (33-63) (rat). Grades: ≥95% by HPLC. CAS No. 41594-08-5. Molecular formula: C135H222N38O49. Mole weight: 3161.43. | |
| [D-Ala2]-GIP (human) | A highly potent GIP receptor agonist (EC50 = 630 ± 119 pM). Displays equivalent cAMP stimulating properties and improved resistance to enzymatic degradation compared to native GIP in cells expressing wild type GIP receptor. Improves glucose tolerance, insulin release and cognitive function in various animal models of obesity and diabetes. Displays neuroprotective effects in an MPTP model of PD. Synonyms: (D-Ala2)-Gastric Inhibitory Polypeptide (human); H-Tyr-D-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH; L-tyrosyl-D-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-isoleucyl-L-histidyl-L-glutaminyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-asparagyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-glycyl-L-lysyl-L-lysyl-L-asparagyl-L-alpha-aspartyl-L-tryptophyl-L-lysyl-L-histidyl-L-asparagyl-L-isoleucyl-L-threonyl-L-glutamine. Grades: ≥98% by HPLC. CAS No. 444073-04-5. Molecular formula: C226H338N60O66S. Mole weight: 4983.53. | |
| des-His1-[Glu9]-Glucagon (1-29) amide | A glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes) that displays no agonist activity. It binds to glucagon receptors to stimulate breakdown of inositol phospholipids by phospholipase C. It was shown to potentiate glucose-stimulated pancreatic insulin release in vitro. It blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats. Synonyms: (Des-His1,Glu9)-Glucagon (1-29) amide (human, rat, porcine); H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2; L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threoninamide. Grades: ≥95%. CAS No. 110084-95-2. Molecular formula: C148H221N41O47S. Mole weight: 3358.68. | |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, acetate (1:x); Exendin 4 (Heloderma suspectum), acetate; Exendin-4 acetate; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2.CH3CO2H. Grades: >98%. CAS No. 914454-01-6. Molecular formula: C184H282N50O60S.C2H4O2. Mole weight: 4246.61. | |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Synonyms: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. Grades: ≥95%. CAS No. 133514-43-9. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. | |
| Gastric Inhibitory Polypeptide (1-30) amide (porcine) | It is a fully glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42). It is a weak inhibitor of gastric acid secretion and a strong stimulator of insulin. The site responsible for insulinotropic activity is apparently located between residues 19 and 30 of GIP. Synonyms: Glucose-Dependent Insulinotropic Polypeptide (1-30) amide (porcine); H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-NH2; L-tyrosyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-asparagyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysinamide; GIP (1-30) amide, porcine. Grades: ≥95%. CAS No. 134846-93-8. Molecular formula: C162H245N41O47S. Mole weight: 3551.04. | |
| Gastric Inhibitory Polypeptide (3-42) (human) | Gastric Inhibitory Polypeptide (3-42) (human), the main physiological degradation product of gastric inhibitory polypeptide (GIP), is produced by proteolytic processing of GIP by dipeptidyl peptidase IV (DPP IV). It is a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist that regulates insulin secretion and GIP metabolism in vivo. Synonyms: GIP (3-42) (human); H-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH; L-Glutamine, L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-isoleucyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-histidyl-L-glutaminyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-asparaginyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysylglycyl-L-lysyl-L-lysyl-L-asparaginyl-L-α-aspartyl-L-tryptophyl-L-lysyl-L-histidyl-L-asparaginyl-L-isoleucyl-L-threonyl-. Grades: ≥95%. CAS No. 1802086-25-4. Molecular formula: C214H324N58O63S. Mole weight: 4749.35. | |
| Gastric Inhibitory Polypeptide (6-30) amide (human) | Gastric Inhibitory Polypeptide (6-30) amide (human), a porcine homolog, antagonizes the induction of cAMP production of gastric inhibitory polypeptide (human) (GIP human) in vitro. Competitive binding studies showed that it exhibited a receptor-binding affinity equivalent to the gastric inhibitory polypeptide (human) with an IC50 of 3.08±0.57 nM. Synonyms: GIP (6-30) amide (human); H-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-NH2; L-phenylalanyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-isoleucyl-L-histidyl-L-glutaminyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-asparagyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysinamide; glucose-dependent insulinotropic polypeptide (6-30) amide (human). Grades: ≥95% by HPLC. CAS No. 1139691-72-7. Molecular formula: C139H209N35O38S. Mole weight: 3010.42. | |
| GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat) | GLP-1 (1-36) amide is a promising peptide hormone unlocking avenues for type 2 diabetes mellitus research. Its extraordinary resemblance to the native GLP-1 facilitates heightened glucose-dependent insulin secretion. Synonyms: Preproglucagon (92-127) amide (human, bovine, guinea pig, mouse, rat); Glucagon-like peptide 1 (1-36) amide (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-argininamide. Grades: ≥95%. CAS No. 99658-04-5. Molecular formula: C184H273N51O57. Mole weight: 4111.44. | |
| GLP-1(7-37) | GLP-1 (7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1 (1-37). It is a potent stimulator of insulin secretion at concentrations as low as 5 X 10(-11) M and has no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M. It participates in the physiological regulation of insulin secretion. Uses: Glp-1 (7-37) acetate participates in the physiological regulation of insulin secretion. Synonyms: Proglucagon (78-108) (human, bovine, guinea pig, mouse, rat); Insulinotropin (human, bovine, guinea pig, mouse, rat); Glucagon-Like Peptide 1 (7-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (98-128) (human, bovine, guinea pig, mouse, rat); GLP-1 (7-37) human; Glucagon-like Peptide-1 (7-37); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grades: 98%. CAS No. 106612-94-6. Molecular formula: C151H228N40O47. Mole weight: 3355.67. | |
| Glucagon-like peptide 1 (1-37), human | Glucagon-like peptide 1 (1-37) is a pancreatic hormone synthesized by post-translational processing of proglucagon. It decreases plasma glucose level in high-fat-fed mice when administered at 25 nmol/kg. Glucagon-like peptide 1 (1-37) exhibits no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. Synonyms: HuGLP-1; GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (92-128) (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grades: ≥95%. CAS No. 87805-34-3. Molecular formula: C186H275N51O59. Mole weight: 4169.48. | |
| PACAP (6-27) | PACAP 6-27 is a potent PACAP receptor antagonist. It induces insulin secretion by pancreatic beta cells. Synonyms: H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2; L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucinamide; Pituitary Adenylate Cyclase-activating Peptide (6-27). Grades: ≥95%. CAS No. 136134-68-4. Molecular formula: C121H193N33O31S. Mole weight: 2638.09. | |
| Peptide YY (3-36) | Peptide YY (3-36) is a Y2/Y5 Neuropeptide Y receptor agonist (IC50= 0.11 nM for inhibition of 125I-PYY binding to Y2 receptor). Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. Synonyms: Peptide YY (PYY) (3-36), human; H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2; L-alanyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-seryl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-leucyl-L-asparagyl-L-leucyl-L-valyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide; PYY (3-36) (canine, mouse, porcine, rat). Grades: 98%. CAS No. 126339-09-1. Molecular formula: C176H272N52O54. Mole weight: 3980.42. | |
| Preptin (rat) | Preptin, a 34-amino acid peptide hormone, is co-secreted with insulin in β-cells of the pancreas in response to glucose stimulation. Preptin is osteogenic both in vitro and in vivo and may act synergistically with other β-cell hormones insulin and amylin to stimulate bone formation in hyperinsulinemic states such as obesity. Synonyms: H-Asp-Val-Ser-Thr-Ser-Gln-Ala-Val-Leu-Pro-Asp-Asp-Phe-Pro-Arg-Tyr-Pro-Val-Gly-Lys-Phe-Phe-Lys-Phe-Asp-Thr-Trp-Arg-Gln-Ser-Ala-Gly-Arg-Leu-OH; L-alpha-aspartyl-L-valyl-L-seryl-L-threonyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-leucyl-L-prolyl-L-alpha-aspartyl-L-alpha-aspartyl-L-phenylalanyl-L-prolyl-L-arginyl-L-tyrosyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-alpha-aspartyl-L-threonyl-L-tryptophyl-L-arginyl-L-glutaminyl-L-seryl-L-alanyl-glycyl-L-arginyl-L-leucine. Grades: ≥95%. CAS No. 315197-73-0. Molecular formula: C181H268N48O51. Mole weight: 3932.41. | |
| Proinsulin C-Peptide (55-89), human | It is a peptide fragment of the cleavage product of proinsulin. Synonyms: C-peptide; Insulin C chain; H-Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg-OH; L-arginyl-L-arginyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-glycyl-L-glutaminyl-L-valyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-seryl-L-leucyl-L-glutaminyl-L-lysyl-L-arginine. Grades: ≥95%. CAS No. 11097-48-6. Molecular formula: C153H259N49O52. Mole weight: 3616.98. | |
| Proinsulin C-peptide human | It is a peptide consisting of 31 amino acids that connects the A and B chains of proinsulin, ensuring that its correct folding, is biologically active and regulates cellular function. Synonyms: Insulin Precursor (57-87) (human); C-Peptide, Proinsulin; Human proinsulin C-peptide; H-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH; L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-glycyl-L-glutaminyl-L-valyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-seryl-L-leucyl-L-glutamine. Grades: 95%. CAS No. 33017-11-7. Molecular formula: C129H211N35O48. Mole weight: 3020.26. | |
| [pTyr1146] [pTyr1150] [pTyr1151]Insulin Receptor 1142-1153 | It binds to insulin and acts as a substrate for insulin receptor tyrosine kinase. Synonyms: L-Lysine, L-threonyl-L-arginyl-L-α-aspartyl-L-isoleucyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-threonyl-L-α-aspartyl-O-phosphono-L-tyrosyl-O-phosphono-L-tyrosyl-L-arginyl-; Thr-Arg-Asp-Ile-pTyr-Glu-Thr-Asp-pTyr-pTyr-Arg-Lys. Grades: ≥95%. CAS No. 141171-54-2. Molecular formula: C72H110N19O33P3. Mole weight: 1862.67. | |
| Semaglutide | Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide. Uses: The treatment of type 2 diabetes. Synonyms: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; BGM 134; NN 9535; NN 9536; NNC 0113-0217; Ozempic; Rybelsus; Wegovy; (3S, 9S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S, 36S, 39S, 45S, 48S, 51S, 54S, 81S)-54-(((6S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S)-21-(.. Grades: >98%. CAS No. 910463-68-2. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) | Serine substitution of alanine significantly improves the plasma stability of GLP-1(7-36) amide to DPP IV, but does not affect its insulinotropic activity. This may indicate that the modification can improve the potential of GLP-1 in the treatment of type 2 diabetes. Synonyms: (Ser79)-Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat); H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidyl-L-seryl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; (Ser8)-Glucagon-Like Peptide 1 (7-36) amide; 8-L-Serine-36-L-argininamide-7-36-glucagon-like peptide I (human). Grades: 95%. CAS No. 215777-46-1. Molecular formula: C149H226N40O46. Mole weight: 3313.68. | |
| Tranilast | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino] benzoic acid, 3,4-DAA, N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Rizaben, SB-252218. recombinant, biosynthetic, fast-acting insulin analogue helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It has a single amino acid substitution at position B28 where proline is replaced with aspartic acid. This substitution decreases its propensity to form hexamers and gives it a higher rate of absorption following subcutaneous administration compared to native insulin. CAS No. 53902-12-8. Product ID: 8-04754. Molecular formula: C18H17NO5. Mole weight: 327.33. | |
| (Tyr0)-C-Peptide (dog) | (Tyr0)-C-Peptide (dog) is a biomedical product used to mimic the action of endogenous C-peptide hormone in dogs. It can potentially study diabetes mellitus type 1 in canines by regulating blood sugar levels and promoting insulin synthesis. Synonyms: Tyr-C-Peptide, dog; H-Tyr-Glu-Val-Glu-Asp-Leu-Gln-Val-Arg-Asp-Val-Glu-Leu-Ala-Gly-Ala-Pro-Gly-Glu-Gly-Gly-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ala-Leu-Gln-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-alpha-aspartyl-L-valyl-L-alpha-glutamyl-L-leucyl-L-alanyl-glycyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-glycyl-glycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-alanyl-L-leucyl-L-glutamine; L-Glutamine, L-tyrosyl-L-α-glutamyl-L-valyl-L-α-glutamyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-α-aspartyl-L-valyl-L-α-glutamyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolylglycyl-L-α-glutamylglycylglycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-α-glutamylglycyl-L-alanyl-L-leucyl-. Grades: 95%. CAS No. 101135-67-5. Molecular formula: C146H234N38O51. Mole weight: 3337.69. | |
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